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Mark Litzow
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Journal Articles

A randomized study of conventional chemotherapy +/- uproleselan in older adults with Acute Myeloid Leukemia eceiving intensive induction chemotherapy (Alliance A041701)

Free
Geoffrey Uy, Jun Yin, Shira Dinner, Meagan Jacoby, Daniel Deangelo, Jane Liesveld, Jonathan Kolitz, Adam Asch, Olatoyosi Odenike, Oudom Kour, Korrie Skogen, Ken Byrd, Richard Little, Steven Gore, Andrew Carroll, Krzysztof Mrózek, John Byrd, Ann-Kathrin Eisfeld, Anthony Jaslowski, Harry Erba, Mark Litzow, Wendy Stock, Richard Stone
Journal: Blood
Blood (2025) 146 (Supplement 1): 3415.
https://doi.org/10.1182/blood-2025-3415
Published: 2025
Journal Articles

Identifying fusions in AML/MDS: An experience from first 400 patients enrolled into myelomatch

Free
Shahanawaz Jiwani, Min Fang, Cecilia Yeung, Xiaoyu QU, Xueyan Chen, Brent Wood, Andrea Zak, Srikrishna Narava, Ting-Chia Chang, Celso Baldivieso, Megha Kamath, Megan Othus, Bhanumati Ramineni, Harry Erba, Mark Litzow, James Doroshow, Lyndsay Harris, Jerald Radich, Richard Little
Journal: Blood
Blood (2025) 146 (Supplement 1): 340.
https://doi.org/10.1182/blood-2025-340
Published: 2025
Journal Articles

Prospective study of patient-reported depression, and cognitive and functional impairment, and impact on survival and induction mortality in fit adults age ≥60 years receiving intensive chemotherapy (IC) for Acute Myeloid Leukemia (AML): Prospective geriatric assessment (GA) report from ECOG-ACRIN (EA) E2906 randomized study

Free
James Foran, Li Chen, Selina Luger, Zhuoxin Sun, Heidi Klepin, Catherine Lai, David Claxton, Hillard Lazarus, Daniel Arber, Jacob Rowe, Elisabeth Paietta, Janis Racevskis, Francine Garrett-Bakelman, Yanming Zhang, Jessica Altman, Aref Al-Kali, Hong Zheng, Keith Pratz, Kristen O'Dwyer, Edward Broun, Bayard Powell, John Godwin, Yishai Ofran, Efrat Dotan, Mark Litzow, Martin Tallman, Lynne Wagner
Journal: Blood
Blood (2025) 146 (Supplement 1): 882.
https://doi.org/10.1182/blood-2025-882
Published: 2025
Journal Articles

Blast clearance dynamics and time to response across IDH1- and IDH2-mutated AML

Free
Mohamad Sheikh Najeeb, Oudai Alkabbani, Rong He, Dragan Jevremovic, Patricia Greipp, Aasiya Matin, Mehrdad Hefazi Torghabeh, Abhishek Mangaonkar, Mrinal Patnaik, Naseema Gangat, William Hogan, Mark Litzow, Cecilia Arana Yi, James Foran, Mithun Shah, Kebede Begna, Hassan Alkhateeb, Tariq Kewan, Antoine Saliba, Aref Al-Kali
Journal: Blood
Blood (2025) 146 (Supplement 1): 7045.
https://doi.org/10.1182/blood-2025-7045
Published: 2025
Journal Articles

Acute Myeloid Leukemia (AML) with TP53 alteration and outcomes after allogeneic hematopoietic stem cell transplantation: A CIBMTR registry study

Free
Alexandra Gomez-Arteaga, Rory Shallis, Mariam Nawas, Landi Guo, Temitope Oloyede, Kwang Woo Ahn, Veronika Bachanova, Michael Byrne, Sergio Giralt, Lohith Gowda, Ann Jakubowski, Mark Litzow, Filippo Milano, Kristin Page, Wael Saber, Nelli Bejanyan, Larisa Broglie, Xinjie Xu, Jean Yared
Journal: Blood
Blood (2025) 146 (Supplement 1): 1060.
https://doi.org/10.1182/blood-2025-1060
Published: 2025
Journal Articles

Time from AML diagnosis to HCT and pre-HCT FLT3 inhibition impact pre-transplant MRD and benefit from post-HCT gilteritinib

Free
Mark Levis, Mehdi Hamadani, Brent Logan, Richard Jones, Anurag Singh, Mark Litzow, John Wingard, Esperanza Papadopoulos, Alexander Perl, Robert Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey Uy, Edmund Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori Muffly, Heeje Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Caroline Chen, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven Devine, Mary Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 1058.
https://doi.org/10.1182/blood-2025-1058
Published: 2025
Journal Articles

Choice of hypomethylating agent for newly diagnosed TP53-mutant Acute Myeloid Leukemia: A command registry study

Free
Talha Badar, Omer Jamy, Chenyu Lin, Anand Patel, Yu-Hung Wang, Rory Shallis, Kendall Diebold, Alex Coltoff, Aaron Goldberg, Jan Philipp Bewersdorf, Kenneth Zabel, Charles Foucar, Yasmin Abaza, Guru Subramanian Guru Murthy, Neil Palmisiano, Adam Duvall, Vamsi Kota, Shyam Patel, Amer Zeidan, Ehab Atallah, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 874.
https://doi.org/10.1182/blood-2025-874
Published: 2025
Journal Articles

Bone marrow biopsy characteristics at nadir after intensive induction therapy do not predict outcomes in acute myeloid leukemia (AML): An analysis of ECOG-ACRIN clinical trials

Free
Douglas Tremblay, Li Chen, Zhuoxin Sun, Chezi Ganzel, Hugo Fernandez, James Foran, Daniel Arber, Hillard Lazarus, Yanming Zhang, Elisabeth Paietta, John Bennett, Jacob Rowe, Mark Litzow, Martin Tallman, Ehab Atallah, Selina Luger
Journal: Blood
Blood (2025) 146 (Supplement 1): 871.
https://doi.org/10.1182/blood-2025-871
Published: 2025
Journal Articles

SWOG 1318: Combination of dasatinib, prednisone, and blinatumomab for older patients with Philadelphia chromosome positive acute lymphoblastic leukemia:  longer follow up and predictors of outcomes

Free
Anjali Advani, Anna Moseley, Kristen O'Dwyer, Cecilia Yeung, Olga Sala Torra, Brent Wood, Jae Park, Matthew Wieduwilt, Deepa Jeyakumar, George Yaghmour, Ehab Atallah, Aaron Gerds, Susan O'Brien, Jane Liesveld, Megan Othus, Mark Litzow, Richard Stone, Jerald Radich, Harry Erba
Journal: Blood
Blood (2025) 146 (Supplement 1): 3343.
https://doi.org/10.1182/blood-2025-3343
Published: 2025
Journal Articles

Inferior survival in black AML patients treated with intensive chemotherapy in ECOG-ACRIN clinical trials is independent of cytogenetic profiles

Free
Shella Saint Fleur-Lominy, Li Chen, Zhuoxin Sun, Francine Garrett-Bakelman, Mihir Shukla, Hugo Fernandez, James Foran, Larry Cripe, Hillard Lazarus, Peter Wiernik, Jacob Rowe, Martin Tallman, Mark Litzow, Yanming Zhang, Selina Luger, Irum Khan
Journal: Blood
Blood (2025) 146 (Supplement 1): 290.
https://doi.org/10.1182/blood-2025-290
Published: 2025
Journal Articles

Sparse whole genome sequencing and machine learning of AML genomes reveals novel, clinically relevant genetics.

Free
Timour Baslan, Pascal Belleau, Astrid Deschênes, Yanming Zhang, Zhuoxin Sun, Francine Garrett-Bakelman, Maria Kleppe, Elisabeth Paietta, Larry Cripe, Hugo Fernandez, Martin Tallman, Jacob Rowe, Hillard Lazarus, Ari Melnick, Mark Litzow, Ross Levine, Nevenka Dimitrova, Selina Luger, Alexander Krasnitz, Scott Lowe
Journal: Blood
Blood (2025) 146 (Supplement 1): 5263.
https://doi.org/10.1182/blood-2025-5263
Published: 2025
Journal Articles

Risk-adjusted comparison of survival in chronic myelomonocytic leukemia with and without allogeneic stem cell transplant: Mayo Clinic experience in 775 consecutive patients

Free
Ali Alsugair, Saubia Fathima, Mohammad Alhousani, Estefania Gauto Mariotti, Priyansh Faldu, Muhammad Yousuf, Abiola Bolarinwa, Clifford Csizmar, James Foran, Abhishek Mangaonkar, Mark Litzow, Hemant Murthy, Lisa Sproat, Jeanne Palmer, Aasiya Matin, Ernesto Ayala, James Slack, Luis Porrata, Madiha Iqbal, Nandita Khera, Nathan Punwani, Saad Kenderian, Saurabh Chhabra, Kebede Begna, Animesh Pardanani, William Hogan, Mithun Shah, Hassan Alkhateeb, Naseema Gangat, Mrinal Patnaik, Ayalew Tefferi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5636.
https://doi.org/10.1182/blood-2025-5636
Published: 2025
Journal Articles

Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR:ABL-1 negative acute lymphoblastic leukemia

Free
Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2025-5120
Published: 2025
Journal Articles

Acute leukemia during pregnancy: A three-decade Mayo Clinic experience

Free
Brittany Kimball, Antoine Saliba, Mahsa Rezasoltani, Kristen McCullough, William Hogan, Mrinal Patnaik, Isla Johnson, Clifford Csizmar, Aldo Acosta Medina, Aref Al-Kali, Hassan Alkhateeb, Kebede Begna, Animesh Pardanani, Nandita Khera, Mark Litzow, Ayalew Tefferi, Naseema Gangat
Journal: Blood
Blood (2025) 146 (Supplement 1): 6408.
https://doi.org/10.1182/blood-2025-6408
Published: 2025
Journal Articles

Clinical outcomes in adult AML with KMT2A rearrangements: A comparative analysis with R/R KMT2Ar and NPM1-mutated AML from the Mayo Clinic

Free
Mahmood Aldapt, Kin Fentie, Joseph Parker, Hemant Murthy, James Foran, Naseema Gangat, Mohamed Kharfan-Dabaja, Jennifer Jiang, Yao-Shan Fan, Aref Al-Kali, Antoine Saliba, Cecilia Arana Yi, Nathan Punwani, Lisa Sproat, Mark Litzow, Mrinal Patnaik, Talha Badar
Journal: Blood
Blood (2025) 146 (Supplement 1): 7030.
https://doi.org/10.1182/blood-2025-7030
Published: 2025
Journal Articles

Phase II Results of ECOG-ACRIN EA9152: A multicenter study of liposomal vincristine (L-VCR) or vincristine sulfate (VCR) and venetoclax (VEN) in relapsed or refractory acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL)

Free
Neil Palmisiano, Juwhei Lee, David Claxton, Elisabeth Paietta, Nikolai Podoltsev, Jae Park, Dale Schaar, Jonathan Webster, Selina Luger, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1577.
https://doi.org/10.1182/blood-2025-1577
Published: 2025
Journal Articles

Impact of therapy delays on outcomes in adults with BCR::ABL1 negative b-lineage acute lymphoblastic leukemia (ALL) in the ECOG-ACRIN E1910 trial randomized to conventional chemotherapy +/- blinatumomab

Free
Bhavana Bhatnagar, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2025-1549
Published: 2025
Journal Articles

Effect of FLT3 maintenance in older FLT3-ITD+ adults undergoing allogeneic HCT. a post hoc analysis of BMT CTN 1506

Free
Sameem Abedin, Victor Baidoo, Aniko Szabo, Richard Jones, Anurag Singh, Mark Litzow, John Wingard, Esperanza Papadopoulos, Alexander Perl, Robert Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey Uy, Edmund Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori Muffly, Heeje Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Caroline Chen, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven Devine, Mary Horowitz, Yi-Bin Chen, Mark Levis, Mehdi Hamadani
Journal: Blood
Blood (2025) 146 (Supplement 1): 170.
https://doi.org/10.1182/blood-2025-170
Published: 2025
Journal Articles

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

Free
Victoria Heigh, Maymona Abdelmagid, Laura Ongie, Kristen McCullough, Jenna Fernandez, Terra Lasho, Christy Finke, Anand Srinivasan, Mira Kohorst, Asmaa Ferdjallah, William Hogan, Ronald Go, David Dingli, Naseema Gangat, Aref Al-Kali, Kebede Begna, Hassan Alkhateeb, Mithun Shah, Mark Litzow, Mehrdad Hefazi Torghabeh, Aasiya Matin, Kaaren Reichard, Joanna Dalland, Yael Kusne, James Foran, Alejandro Ferrer, Mrinal Patnaik, Abhishek Mangaonkar
Journal: Blood
Blood (2025) 146 (Supplement 1): 6750.
https://doi.org/10.1182/blood-2025-6750
Published: 2025
Journal Articles

The need for re-induction based on D14-residual acute myeloid leukemia in patients achieving complete remission predicts higher relapse rate and inferior post-remission survival

Free
Abiola Bolarinwa, Mohammad Yousuf, Aref Al-Kali, Hassan Alkhateeb, Abhishek Mangaonkar, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, Michelle Elliott, Mark Litzow, William Hogan, Mithun Shah, Mrinal Patnaik, Animesh Pardanani, Dong Chen, Kaaren Reichard, Rong He, Naseema Gangat, Ayalew Tefferi, Kebede Begna
Journal: Blood
Blood (2025) 146 (Supplement 1): 1605.
https://doi.org/10.1182/blood-2025-1605
Published: 2025