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Journal Articles

Updated Efficacy and Safety Results of Patients Receiving Selected 100mg Bezuclastinib Dose and Participating in the Open-Label Extension of Summit: A Randomized, Double-Blind, Placebo Controlled Phase 2 Clinical Trial of Bezuclastinib in Adult Patients with Nonadvanced Systemic Mastocytosis

Lindsay A.M. Rein, Daniel J. DeAngelo, Brian Modena, Stephen Oh, Bulai Livideanu Cridtina, Celalettin Ustun, Nathan Boggs, Michael Manning, Anthony M. Hunter, Cem Akin, Arnold Kirshenbaum, Ingunn Dybedal, Cecilia Y. Arana Yi, Richard Herrscher, Mariana Castells, Frederick Lansigan, Tracy I. George, Jay Patel, Lei Sun, Nisha Shah, Jenna Zhang, Amanda Pilla, Priya Singh, Marcus Carden, Frank Siebenhaar, Prithviraj Bose
Journal: Blood
Blood (2024) 144 (Supplement 1): 4556.
https://doi.org/10.1182/blood-2024-194551
Published: 2024
Journal Articles

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L Uy, Edmund K. Waller, Sumithira Vasu, Melhem M. Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Heather Wittsack, Adam Mendizabel, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 973.
https://doi.org/10.1182/blood-2023-177929
Published: 2023
Journal Articles

Gold is gold even in mud: NPM1 mutations in T-AML

Celalettin Ustun
Journal: Blood
Blood (2023) 141 (15): 1784–1785.
https://doi.org/10.1182/blood.2022019295
Published: 2023
Journal Articles

Preliminary Safety and Efficacy from Apex, a Phase 2 Study of Bezuclastinib (CGT9486), a Novel, Highly Selective, Potent KIT D816V Tyrosine Kinase Inhibitor, in Adults with Advanced Systemic Mastocytosis (AdvSM)

Daniel J. DeAngelo, Vinod A. Pullarkat, Miguel Piris-Villaespesa, Tracy I. George, Jay L. Patel, Celalettin Ustun, Prithviraj Bose, Mark L Heaney, Jessica Sachs, Lei Sun, Amanda Pilla, Benjamin Exter, Hina A. Jolin, Tsewang Tashi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1512–1513.
https://doi.org/10.1182/blood-2022-156311
Published: 2022
Journal Articles

Phase 2 Results of Urinary-Derived Human Chorionic Gonadotropin/Epidermal Growth Factor As Treatment for Life-Threatening Acute Gvhd

Shernan G Holtan, Celalettin Ustun, Andrea Hoeschen, Julianne Feola, Qing Cao, Parth Gandhi, Wes Mosher, Chi Chen, Arne Slungaard, Armin Rashidi, Erica D. Warlick, Mukta Arora, Veronika Bachanova, Fiona He, Brian C. Betts, Gregory M. Vercellotti, Claudio G. Brunstein, Najla H El Jurdi, Ashish O. Gupta, Murali Janakiram, Joseph E. Maakaron, Angela Panoskaltsis-Mortari, Daniel J. Weisdorf, Margaret L. MacMillan
Journal: Blood
Blood (2021) 138 (Supplement 1): 261.
https://doi.org/10.1182/blood-2021-145008
Published: 2021
Journal Articles

The Incidence and Impact of Clostridioides Difficile Infection (CDI) on Outcomes after Allogeneic Hematopoietic Cell Transplant (alloHCT) - a CIBMTR Study

Muthalagu Ramanathan, Bipin B. Savani, Naya He, Soyoung Kim, Min Chen, Roy Chemaly, Christopher E Dandoy, Miguel-Angel Perales, Marcie L. Riches, Celalettin Ustun
Journal: Blood
Blood (2021) 138 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2021-145774
Published: 2021
Journal Articles

The Impact of Non-Clinical Factors in Clinical Trial Enrollments of Patients with Hematologic Malignancies

Jamile M. Shammo, Anne Timmermann, Deborah A. Katz, Agne Paner, Seo-Hyun Kim, Irene dehghan-Paz, Melissa L. Larson, Parameswaran Venugopal, Celalettin Ustun, Ankur Varma, Sunita Nathan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1914.
https://doi.org/10.1182/blood-2021-148135
Published: 2021
Journal Articles

Outcomes of COVID-19 Infection in Patients with Hematologic Malignancies

Elizabeth Behrens, MD, Anne Timmermann, Alexander Yerkan, Deborah A. Katz, MD, Agne Paner, MD, Melissa C. Larson, MD, Seo-Hyun Kim, MD, Shivi Jain, MDMBBS, Sefer Gezer, MD, Parameswaran Venugopal, MD, Irene Dehghan-Paz, Yoona Rhee, Celalettin Ustun, MD, Ankur Varma, Jamile M. Shammo, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-141063
Published: 2020
Journal Articles

Non-Infectious Pulmonary Toxicity after Allogeneic Hematopoietic Cell Transplantation (HCT): A Center for International Blood and Marrow Transplant Research (CIBMTR) Study

Sagar S. Patel, MD, Kwang Woo Ahn, PhD, Manoj Khanal, BS, MS, Caitrin Fretham, MPH, Celalettin Ustun, MD, Betty K. Hamilton, MD, Navneet S. Majhail, MD MS, Shin Mineishi, MD, Bipin N. Savani, MD, Mohamed Sorror, MD MSc, Edward A. Stadtmauer, MD FACP, Brent Logan, PhD, Marcelo C. Pasquini, MDMS, Saurabh Chhabra, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-140503
Published: 2020
Journal Articles

Evaluation of Patients with PNH Treated By Eculizumab: Real World Data from Turkey

Fatma Keklik Karadag, MD, Mustafa Nuri Yenerel, MD, Yılmaz Mehmet, MD, Hava uskudar Teke, MD, Vildan Ozkocaman, MD, Tulin Tuglular, MD, Fuat Erdem, MD, Ali Unal, MD, Orhan Ayyildiz, MD, Gulsum Ozet, MD, Melda Ozkan, MD, Emin Kaya, MD, Mesut Ayer, MD, Ozan Salim, MD, Birol Güvenç, MD, Hakan Ozdogu, MD, Özgür Mehtap, MD, Mehmet Sönmez, MD, Nil Güler, MD, Sibel Kabukcu Hacioglu, MD, Ismet Aydogdu, MD, Ozlen Bektas, MD, Selami Kocak Toprak, MD, Lale Kaynar, MD, Munci Yagci, MD, Salih Aksu, MDPROF., Anil Tombak, MD, Volkan Karakus, MD, Irfan Yavasoglu, MD, Birgül Öneç, MD, Mehmet Ali Özcan, MD, Levent Ündar, MD, Rıdvan Ali, MD, Celalettin Ustun, MD, Osman Ilhan, MD, Guray Saydam, MD, Fahri Sahin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4805.
https://doi.org/10.1182/blood-2019-128743
Published: 2019
Journal Articles

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Shernan G. Holtan, MD, Andrea Hoeschen, Qing Cao, MS, Mukta Arora, MD, Veronika Bachanova, MD PhD, Claudio G Brunstein, MD PhD, Sarah Cooley, MD, Jeffrey S. Miller, MD, Arne Slungaard, MD, Celalettin Ustun, MD, Armin Rashidi, MD PhD, Gregory M Vercellotti, MD FACP, Erica D. Warlick, MD, Todd E. DeFor, MS, John E. Wagner, MD, Bruce R. Blazar, MD, Pamala A. Jacobson, PharmD, Angela Panoskaltsis-Mortari, PhD, Margaret L. MacMillan, MD, Daniel J. Weisdorf, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 71.
https://doi.org/10.1182/blood-2018-99-113564
Published: 2018
Journal Articles

Allogeneic Hematopoietic Cell Transplantation (HCT) Vs. Non-HCT Consolidation Therapies in Acute Myeloid Leukemia (AML) Patients 60-75 Years of Age in First Complete Remission (CR1): An Alliance (A151509), SWOG, ECOG-ACRIN and CIBMTR Study

Celalettin Ustun, MD, Jennifer Le-Rademacher, PhD, Hai-Lin Wang, MPH, Megan Othus, Zhuoxin Sun, PhD, Brittny Major, Mei-Jie Zhang, PhD, Elizabeth Storrick, Jacqueline M Lafky, Selina Chow, Krzysztof Mrózek, MD PhD, Eyal C. Attar, MD, Clara D. Bloomfield, MD, Larry D Cripe, MD, Richard A. Larson, MD, Guido Marcucci, Gail J. Roboz, MD, Geoffrey L. Uy, MD, Richard M. Stone, MD, Aminah Jatoi, Thomas C. Shea, MD, Marcos de Lima, MD, James M. Foran, MD, Brenda M. Sandmaier, MD, Mark R. Litzow, MD, Harry P. Erba, MD PhD, Arti Hurria, MD, Daniel J. Weisdorf, MD, Andrew S Artz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2170.
https://doi.org/10.1182/blood-2018-99-118383
Published: 2018
Journal Articles

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Clinical Trials & Observations
Rizwan Romee, Sarah Cooley, Melissa M. Berrien-Elliott, Peter Westervelt, Michael R. Verneris, John E. Wagner, Daniel J. Weisdorf, Bruce R. Blazar, Celalettin Ustun, Todd E. DeFor, Sithara Vivek, Lindsey Peck, John F. DiPersio, Amanda F. Cashen, Rachel Kyllo, Amy Musiek, András Schaffer, Milan J. Anadkat, Ilana Rosman, Daniel Miller, Jack O. Egan, Emily K. Jeng, Amy Rock, Hing C. Wong, Todd A. Fehniger, Jeffrey S. Miller
Journal: Blood
Blood (2018) 131 (23): 2515–2527.
https://doi.org/10.1182/blood-2017-12-823757
Published: 2018
Includes: Supplemental data
Journal Articles

Reduced Intensity Conditioning for Allogeneic Transplantation: Modified Fludarabine Dose Plus Cyclophosphamide/Total Body Irradiation Yields Promising Outcomes

Erica D. Warlick, MD, Todd E. DeFor, MS, Celalettin Ustun, MD, Nelli Bejanyan, MD, Claudio G Brunstein, MD PhD, Margaret L. MacMillan, MD, Daniel J. Weisdorf, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5465.
https://doi.org/10.1182/blood.V130.Suppl_1.5465.5465
Published: 2017
Journal Articles

Final Results of the Chrysalis Trial: A First-in-Human Phase 1/2 Dose-Escalation, Dose-Expansion Study of Gilteritinib (ASP2215) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)

Alexander E. Perl, MD, Jessica K. Altman, MD, Jorge E. Cortes, MD, Catherine C. Smith, MD, Mark Litzow, MD, Maria R. Baer, MD, David F. Claxton, MD, Harry P. Erba, MD PhD, Stanley C. Gill, PhD, Stuart L. Goldberg, MD, Joseph G. Jurcic, MD, Richard A. Larson, MD, Charles Liu, PhD, Ellen K. Ritchie, MD, Gary J. Schiller, MD, Alexander I. Spira, MD PhD, Stephen A. Strickland, Raoul Tibes, MD PhD, Celalettin Ustun, MD, Eunice S. Wang, MD, Robert K. Stuart, MD, Christoph Röllig, MD, Andreas Neubauer, Giovanni Martinelli, Erkut Bahceci, MD, Mark J. Levis, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1069.
https://doi.org/10.1182/blood.V128.22.1069.1069
Published: 2016
Journal Articles

Allogeneic Hematopoietic Cell Transplantation for Elderly Patients: Prognosis Determined By Disease Risk Index

Fiona C. He, MD, Aleksandr Lazaryan, MD PhD MPH, Qing Cao, M.S., Claudio G Brunstein, MD, Shernan G. Holtan, MD, Erica D. Warlick, MD, Celalettin Ustun, MD, Brian McClune, DO, Mukta Arora, MD, Daniel J. Weisdorf, MD, Nelli Bejanyan, MD
Journal: Blood
Blood (2016) 128 (22): 2305.
https://doi.org/10.1182/blood.V128.22.2305.2305
Published: 2016
Journal Articles

Umbilical Cord Blood Transplantation and Delay Engraftment Are Associated with Increased Risks of Diffuse Alveolar Hemorrhage

Ezzideen Barjes Alrawi, MD, Fatma Keklik., MD, Qing Cao, MS, Nelli Bejanyan, MD, Margaret L. MacMillan, MD, Mukta Arora, MD, Erica D. Warlick, MD, Claudio G Brunstein, MD, Daniel J. Weisdorf, MD, Celalettin Ustun, MD
Journal: Blood
Blood (2016) 128 (22): 2222.
https://doi.org/10.1182/blood.V128.22.2222.2222
Published: 2016
Journal Articles

The Effect of Measurable Residual Disease at the Time of Allogeneic Hematopoietic Cell Transplantation on Outcomes in Patients with Acute Myeloid Leukemia: A Meta-Analysis

Sarah A. Buckley, MD, Brent L. Wood, MD PhD, Megan Othus, PhD, Christopher S. Hourigan, MD PhD, Celalettin Ustun, MD, Michael A. Linden, MD PhD, Todd E. DeFor, MS, Michele Malagola, MD PhD, Christopher G. Kanakry, MD, Bernd Gruhn, MD, Beth Devine, PhD PharmD, Roland B. Walter, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2842.
https://doi.org/10.1182/blood.V128.22.2842.2842
Published: 2016
Journal Articles

Resolution of osteosclerosis after alloHCT in systemic mastocytosis

Celalettin Ustun, Elizabeth L. Courville
Journal: Blood
Blood (2016) 127 (14): 1836.
https://doi.org/10.1182/blood-2016-01-690669
Published: 2016
Journal Articles

Similar Survival after Umbilical Cord Blood (UCB) and HLA-Matched Adult Donor Transplantation By Disease Risk Index (DRI) Assignment

Nelli Bejanyan, MD, Claudio G Brunstein, MD, Qing Cao, Aleksandr Lazaryan, MD PhD MPH, Erica D. Warlick, MD, Celalettin Ustun, MD, Shernan G. Holtan, MD, Mukta Arora, MD, Veronika Bachanova, MD, Michael R. Verneris, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD
Journal: Blood
Blood (2015) 126 (23): 4375.
https://doi.org/10.1182/blood.V126.23.4375.4375
Published: 2015