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Mark R. Litzow
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Journal Articles

TP53 mutations and Complex Karyotype in Newly-Diagnosed Blast/Accelerated Phase MPN Are Associated with Ephemeral Response to Treatment with Venetoclax + HMA and Poor Survival

Naseema Gangat, Kristen B. McCullough, Azeem Elbeih, Nour Ghosoun, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Mark R. Litzow, Mehrdad Hefazi, William J. Hogan, Abhishek A. Mangaonkar, Antoine N. Saliba, Mithun V Shah, Talha Badar, James M. Foran, Jeanne Palmer, Cecilia Y. Arana Yi, Mrinal M. Patnaik, Animesh D. Pardanani, Ayalew Tefferi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6657.
https://doi.org/10.1182/blood-2024-193917
Published: 2024
Journal Articles

EBF1 Activity Controls Leukemia Sensitivity to Inotuzumab Ozogamicin

Carolin S. Escherich, Zhenhua Li, Kelly R. Barnett, Yizhen Li, Megan Walker, Wenjian Yang, Xin Huang, Jiyang Yu, Wendy Stock, Elisabeth Paietta, Marina Konopleva, Steven M. Kornblau, Mark R. Litzow, Hiroto Inaba, Ching-Hon Pui, Mignon L. Loh, Daniel Savic, Jun J. Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 830.
https://doi.org/10.1182/blood-2024-198800
Published: 2024
Journal Articles

Predictors of Relapse and Post-Relapse Outcomes in Patients with Newly-Diagnosed Acute Myeloid Leukemia Treated with Venetoclax + Hypomethylating Agent

Azeem Elbeih, Nour Ghosoun, Kristen B. McCullough, Isla Johnson, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Abhishek A. Mangaonkar, Aasiya Matin, Antoine N. Saliba, Mehrdad Hefazi, Mark R. Litzow, William J. Hogan, Mithun V Shah, Mrinal M. Patnaik, Animesh D. Pardanani, Talha Badar, Hemant S. Murthy, James M. Foran, Jeanne Palmer, Lisa Sproat, Nandita Khera, Cecilia Y. Arana Yi, Ayalew Tefferi, Naseema Gangat
Journal: Blood
Blood (2024) 144 (Supplement 1): 2852.
https://doi.org/10.1182/blood-2024-209015
Published: 2024
Journal Articles

A Randomized Phase II Study of Venetoclax and HMA-Based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia (AML): A Myelomatch Treatment Trial: ECOG-ACRIN MM20A-EA02

Jessica Kaplan Altman, Zhuoxin Sun, Alexander E. Perl, Richard Little, Steven D. Gore, Laura C. Michaelis, Geoffrey L. Uy, Yasmin Abaza, Sameem Abedin, John L. Reagan, Ehab L. Atallah, Selina Luger, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 2907.1.
https://doi.org/10.1182/blood-2024-199701
Published: 2024
Journal Articles

Clinical Characteristics of Myeloproliferative Neoplasms in Patients with DDX41 MT Germline Predisposition Syndrome

Yael Kusne, Talha Badar, Terra L. Lasho, Ludovica Marando, Abhishek A. Mangaonkar, Christy Finke, James M. Foran, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Jeanne Palmer, David Viswanatha, Mark R. Litzow, Animesh D. Pardanani, Ayalew Tefferi, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 3183.
https://doi.org/10.1182/blood-2024-202406
Published: 2024
Journal Articles

Gilteritinib Results in Higher Remission and Transplant Rates Than Midostaurin but Does Not Increase the Post-Induction Mutational MRD Negative Rate: Results of the Phase 2 Randomized Precog 0905 Study in Newly Diagnosed FLT3 Mutated AML

Selina Luger, Li Chen, Keith W. Pratz, Sanam Loghavi, Alexander E. Perl, Jessica K. Altman, Robert L. Redner, Amir T. Fathi, Ayman Qasrawi, Adam S. Asch, Deepa Jeyakumar, James M. Foran, Mithun V Shah, Jonathan E Kolitz, Ellin Berman, Lindsay Wilde, Sameem Abedin, Vamsi K. Kota, Krishna Gundabolu, Kristen M. O'Dwyer, Emily K Curran, Ashwin Kishtagari, Kelly Ross, Zhuoxin Sun, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 221.
https://doi.org/10.1182/blood-2024-201595
Published: 2024
Journal Articles

Measurable Residual Mutated NPM1 before Allogeneic Transplant for Acute Myeloid Leukemia

Rasha W Al-Ali, Gege Gui, Niveditha Ravindra, Georgia Andrew, Devdeep Mukherjee, Zoe Wong, Ying Huang, Jason Gerhold, Matthew Holman, Austin Jacobsen, Julian D'Angelo, Jeffrey E Miller, Karina Elias, Jeffery J. Auletta, Firas El Chaer, Steven M. Devine, Antonio M. Jimenez Jimenez, Marcos de Lima, Mark R. Litzow, Partow Kebriaei, Wael Saber, Stephen R. Spellman, Scott L. Zeger, Kristin Page, Coleman Lindsley, Jerald P. Radich, Christopher S. Hourigan, Laura W Dillon
Journal: Blood
Blood (2024) 144 (Supplement 1): 2950.
https://doi.org/10.1182/blood-2024-194922
Published: 2024
Journal Articles

Venetoclax in Combination with Hypomethylating Agent (HMA) Compared to HMA Alone Improves Response but Not Survival in TP53- mutated High-Risk Myelodysplastic Syndrome: Real-World Mayo Clinic Series

Talha Badar, Kashish J. Shah, Mobachir El Kettani, James M. Foran, Mohamed A. Kharfan-Dabaja, Hemant S. Murthy, Naseema Gangat, Aref Al-Kali, Mithun V Shah, Hassan B Alkhateeb, Antoine N. Saliba, William J. Hogan, Cecilia Y. Arana Yi, Lisa Sproat, Jeanne Palmer, Mark R. Litzow, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 1823.
https://doi.org/10.1182/blood-2024-203825
Published: 2024
Journal Articles

Prevalence and Clinical Features of Non-Myeloid Neoplasms in Patients with DDX41 Mutant Germline Predisposition Syndrome

Yael Kusne, Talha Badar, Terra L. Lasho, Ludovica Marando, Abhishek A. Mangaonkar, Christy Finke, James M. Foran, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Jeanne Palmer, David Viswanatha, Mark R. Litzow, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 440.
https://doi.org/10.1182/blood-2024-203879
Published: 2024
Journal Articles

Addition of Inotuzumab to a Pediatric Inspired Chemotherapy Regimen in Young Adult Patients with B-Cell Acute Lymphoblastic Leukemia: Findings from the Alliance A041501 Phase 3 Randomized Trial

Daniel J. DeAngelo, Jun Yin, Anjali S. Advani, Selina Luger, Jill Fulcher, Michaela Liedtke, Geoffrey L. Uy, Shira N. Dinner, Lindsay Wilde, Marlise R. Luskin, Caner Saygin, Ella Postich, Noreen Fulton, Richard C. Harvey, Gaby E Perez Burbano, Rebecca Teske, Harry P. Erba, Mark R. Litzow, Richard M. Stone, Wendy Stock
Journal: Blood
Blood (2024) 144 (Supplement 1): 308.
https://doi.org/10.1182/blood-2024-209438
Published: 2024
Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Michaela Liedtke, Zhuoxin Sun, Mark R. Litzow, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry P. Erba, Richard M. Stone, Selina Luger, Charles G. Mullighan, Martin S. Tallman, Matthew J. Wieduwilt
Journal: Blood
Blood (2024) 144 (Supplement 1): 779.
https://doi.org/10.1182/blood-2024-207557
Published: 2024
Journal Articles

Impact of Time from Diagnosis to Treatment on Outcomes of Adults with AML Treated with HMA and Venetoclax: A US-Based, Multi-Center, Real-World, Retrospective Analysis from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Samuel J. Yates, Julian J. Weiss, Abigail Sneider, Emily Geramita, Guru Subramanian Guru Murthy, Talha Badar, Annie Im, Chenyu Lin, Wei Cheng, Eric S. Winer, Yasmin Abaza, Mark R. Litzow, Ehab L. Atallah, Alok Swaroop, Anand Ashwin Patel, Rory M. Shallis
Journal: Blood
Blood (2024) 144 (Supplement 1): 447.
https://doi.org/10.1182/blood-2024-207116
Published: 2024
Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Nikolai A. Podoltsev, Zhuoxin Sun, Mark R. Litzow, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard M. Stone, Charles G. Mullighan, Martin S. Tallman, Selina Luger, Ryan J Mattison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4211.
https://doi.org/10.1182/blood-2024-207143
Published: 2024
Journal Articles

Association between Body Mass Index and Outcomes in Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Hypomethylating Agents and Venetoclax

Julian J. Weiss, Samuel J. Yates, Talha Badar, Anand Ashwin Patel, Eric S. Winer, Mark R. Litzow, Wei Cheng, Chenyu Lin, Rory M. Shallis
Journal: Blood
Blood (2024) 144 (Supplement 1): 1489.
https://doi.org/10.1182/blood-2024-206670
Published: 2024
Journal Articles

Leukemia Physician's Perspective on Transplant in Patients with TP53 Mutated Acute Myeloid Leukemia

Yenny Alejandra Moreno Vanegas, Suhaib Younis Mohamed El Khatib, Brooke Hisrich, Alexander Coltoff, Rory M. Shallis, Anand Ashwin Patel, Jan Philipp Bewersdorf, Timothy S. Oh, Yasmin Abaza, Charles Foucar, Aaron D. Goldberg, Adam S. Duvall, Ehab L. Atallah, Mark R. Litzow, Talha Badar
Journal: Blood
Blood (2024) 144 (Supplement 1): 1487.
https://doi.org/10.1182/blood-2024-205782
Published: 2024
Journal Articles

Response-Stratified Genetic Risk Model for Newly-Diagnosed Acute Myeloid Leukemia Treated with Venetoclax + Hypomethylating Agent

Naseema Gangat, Azeem Elbeih, Nour Ghosoun, Kristen B. McCullough, Isla Johnson, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Abhishek A. Mangaonkar, Aasiya Matin, Antoine N. Saliba, Mehrdad Hefazi, Mark R. Litzow, William J. Hogan, Mithun V Shah, Mrinal M. Patnaik, Animesh D. Pardanani, Talha Badar, Hemant S. Murthy, James M. Foran, Jeanne Palmer, Lisa Sproat, Nandita Khera, Cecilia Y. Arana Yi, Ayalew Tefferi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4247.
https://doi.org/10.1182/blood-2024-204114
Published: 2024
Journal Articles

PPM1D Somatic Mutations in Myeloid Neoplasms: Clinical Profile, Clonal Characteristics and Impact of Concurrent Somatic TP53 Mutations

Talha Badar, Mobachir El Kettani, Kashish J. Shah, Terra L. Lasho, Yael Kusne, Christy M Finke, James M. Foran, Mohamed A. Kharfan-Dabaja, Hemant S. Murthy, Yao-Shan Fan, Liuyan Jiang, Naseema Gangat, Abhishek A. Mangaonkar, Aref Al-Kali, Ludovica Marando, Ayalew Tefferi, Rong He, David Viswanatha, Mark R. Litzow, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 3218.
https://doi.org/10.1182/blood-2024-202688
Published: 2024
Journal Articles

Characteristics and Outcomes of Patients with Second Hematological Malignancies after Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Binoy Yohannan, Angela Dispenzieri, Francis Buadi, David Dingli, Nelson Leung, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, Joselle Cook, Moritz Binder, Suzanne R Hayman, Yi Lin, Ronald S Go, Rahma M Warsame, Vincent Rajkumar, Shaji Kumar, Eli Muchtar, Hassan B Alkhateeb, William J. Hogan, Mark R. Litzow, Mrinal M. Patnaik, Aref Al-Kali, Abhishek Mangaonkar, Robert C Wolf, Mithun V Shah, Morie A. Gertz
Journal: Blood
Blood (2024) 144 (Supplement 1): 5149.
https://doi.org/10.1182/blood-2024-210932
Published: 2024
Journal Articles

Evidence-Based Risk Stratification of TP53 -Mutated Myeloid Neoplasms

Mithun V Shah, Kevin Hung, Anmol Baranwal, Zoe Price, Aref Al-Kali, Carla Toop, Patricia Greipp, Anna Brown, Dariusz Ladon, Dong Chen, Kebede Begna, Monika Kutyna, Danielle Rud, Mark R. Litzow, William J. Hogan, Peter Bardy, Talha Badar, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan B Alkhateeb, Abhishek A. Mangaonkar, Daniel Thomas, Christopher N. Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2024) 144 (Supplement 1): 3213.
https://doi.org/10.1182/blood-2024-198269
Published: 2024
Journal Articles

The Incidence of CNS Relapse in Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) and Its Impact on Clinical Outcome: Results from Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Kashish J. Shah, Mobachir El Kettani, Ravi Narra, Alice Mims, Alexander Coltoff, Georgio Medawar, Brooke Hisrich, Rory M. Shallis, Cameron J. Hunter, Vamsi K. Kota, Tamer Othman, Brian A. Jonas, Shreya Desai, Guilherme Sacchi de Camargo Correia, Anand Ashwin Patel, Adam S. Duvall, Neil D. Palmisiano, Emily K Curran, Zulfa Omer, Anjali S. Advani, Ehab L. Atallah, Mark R. Litzow, Talha Badar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4184.
https://doi.org/10.1182/blood-2024-205812
Published: 2024