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Journal Articles

Revolutionizing B-ALL Cell Line Development: Novel Generation to Uncover Therapeutic Vulnerabilities

Yiming Wu, Katarzyna Szoltysek, Tony Brown, Emily Backhaus, Tanya Khan, Qingsong Gao, Amanda Brewer, Yunchao Chang, Kathryn G. Roberts, Kristine R Crews, Ilaria Iacobucci, Ruth Wang'ondu, Charles G. Mullighan

Blood (2024) 144 (Supplement 1): 5829.

https://doi.org/10.1182/blood-2024-210486

Published: 2024

Journal Articles

Lessons Learned from Mapping the Process of De-Implementation of Routine Cytogenetics in the Diagnosis of Pediatric Acute Lymphoblastic Leukemia

Marta Salek, Kenneth Busby, III, Nathaniel Webb, Dylan Graetz, Charles G. Mullighan, Thomas B. Alexander, Nickhill Bhakta, Megan C Roberts, Lu Wang

Blood (2024) 144 (Supplement 1): 7599.

https://doi.org/10.1182/blood-2024-211054

Published: 2024

Journal Articles

The Histone Acetyltransferase MOZ (KAT6A) Is a Molecular Dependency and Therapeutic Target in NUP98 -Rearranged Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 825.

https://doi.org/10.1182/blood-2024-210529

Published: 2024

Journal Articles

Differential Role of Crebbp Missense and Truncating Mutations in the Malignant Transformation of Germinal Center B Cells

Chuanjiang Yu, Mara Holloman, Andrew Kim, Yunchao Chang, Antony Holmes, Bowen Cai, Stefanie N Meyer, Katia Basso, Govind Bhagat, Riccardo Dalla-Favera, Charles G. Mullighan, Laura Pasqualucci

Blood (2024) 144 (Supplement 1): 47.

https://doi.org/10.1182/blood-2024-208876

Published: 2024

Journal Articles

Refined Immunophenotypic Criteria Using CD184 and CD165 Improves Sensitivity of Identification of ETP T-ALL

Monica Singh, David Westerman, Stuart S. Winter, Kimberly P. Dunsmore, David T. Teachey, Rawan Shraim, Petri Pölönen, Charles G. Mullighan, Brent L. Wood

Blood (2024) 144 (Supplement 1): 5923.

https://doi.org/10.1182/blood-2024-209533

Published: 2024

Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Blood (2024) 144 (Supplement 1): 1464.

https://doi.org/10.1182/blood-2024-211090

Published: 2024

Journal Articles

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Blood (2024) 144 (Supplement 1): 313.

https://doi.org/10.1182/blood-2024-203827

Published: 2024

Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Blood (2024) 144 (Supplement 1): 779.

https://doi.org/10.1182/blood-2024-207557

Published: 2024

Journal Articles

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Masayuki Umeda, Nicole L Michmerhuizen, Ryan Hiltenbrand, Juan M Barajas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover, Petri Pölönen, Cristina Mecucci, Danika Di Giacomo, Franco Locatelli, Riccardo Masetti, Salvatore Bertuccio, Martina Pigazzi, Ilaria Iacobucci, Charles G. Mullighan, Jeffery M Klco

Blood (2024) 144 (Supplement 1): 325.

https://doi.org/10.1182/blood-2024-210208

Published: 2024

Journal Articles

Inhibiting Free Fatty Acid Transport to Improve CAR-T Cell Therapy of Relapsed B-Cell Acute Lymphoblastic Leukemia

Clarissa Garcia, Kaylyn Lyons, Tian Liu, Ilaria Iacobucci, Amanda Novak, Amy Argabright, Alexis Donnelly, Julian Grandvallet Contreras, Huimin Geng, Sabrina Smith, Xin Zhou, Markus Müschen, John Edgar Dick, Julie R Haines, Angelo D'Alessandro, Charles G. Mullighan, Tzu Phang, M. Eric Kohler, Matthew Witkowski

Blood (2024) 144 (Supplement 1): 1446.

https://doi.org/10.1182/blood-2024-201015

Published: 2024

Journal Articles

A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

Blood (2024) 144 (Supplement 1): 2830.

https://doi.org/10.1182/blood-2024-198354

Published: 2024

Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Blood (2024) 144 (Supplement 1): 4211.

https://doi.org/10.1182/blood-2024-207143

Published: 2024

Journal Articles

Safety and Feasibility of Blinatumomab As Frontline Therapy for Pediatric Patients with B-Acute Lymphoblastic Leukemia and Lymphoma: St. Jude Total Therapy Study XVII

Caitlyn Duffy, Elizabeth Dang, Zhou Yinmei, Jessica Bell, Nickhill Bhakta, Meret Henry, Kenneth Matthew Heym, Sima Jeha, Norman J. Lacayo, Seth E. Karol, Seong Lin Khaw, Raul C. Ribeiro, Deborah E. Schiff, Charles G. Mullighan, Jun J. Yang, Cheng Cheng, Ching-Hon Pui, Hiroto Inaba

Blood (2024) 144 (Supplement 1): 4208.

https://doi.org/10.1182/blood-2024-209284

Published: 2024

Journal Articles

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

Masahiro Uni, Asher Preska Steinberg, Alicia Slavit, Sophia Rha, Shuyuan Cheng, Laura K. Schmalbrock, Jiayu Su, Jing Ma, Andrew McPherson, Charles G. Mullighan, Torsten Haferlach, Ilaria Iacobucci, Jeffery M Klco, Raul Rabadan, Alex Kentsis

Blood (2024) 144 (Supplement 1): 4149.

https://doi.org/10.1182/blood-2024-200137

Published: 2024

Journal Articles

Impact of Ph-like Gene Signatures on Clinical Outcomes in Adult B-ALL Patients in Resource-Constrained Settings

Keli Lima, César Alexander Ortiz Rojas, Frederico Lisboa Nogueira, Wellington F. Silva, Rita de Cássia Cavaglieri Medeiros, Luciana Nardinelli, Aline de Medeiros Leal, Elvira D. R. P. Velloso, Israel Bendit, Alvaro J Alencar, Charles G. Mullighan, João Agostinho Machado-Neto, Eduardo M. Rego

Blood (2024) 144 (Supplement 1): 2802.

https://doi.org/10.1182/blood-2024-208763

Published: 2024

Journal Articles

Classification and risk stratification in T-lineage acute lymphoblastic leukemia

Petri Pölönen, Charles G. Mullighan, David Trent Teachey

Blood blood.2023022920.

https://doi.org/10.1182/blood.2023022920

Published: 2024

Journal Articles

Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Katelyn Purvis, Yinmei Zhou, Seth E. Karol, Jeffrey E. Rubnitz, Raul C. Ribeiro, Shawn HR Lee, Jun J. Yang, W. Paul Bowman, Lu Wang, Stephanie B Dixon, Kathryn G Roberts, Qingsong Gao, Cheng Cheng, Charles G. Mullighan, Sima Jeha, Ching-Hon Pui, Hiroto Inaba

Blood blood.2024024936.

https://doi.org/10.1182/blood.2024024936

Published: 2024

Includes: Supplemental data

Journal Articles

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Blood (2024) 144 (1): 61–73.

https://doi.org/10.1182/blood.2024023930

Published: 2024

Includes: Supplemental data

Journal Articles

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A. Betram, Richard Moriggl, Thomas Rülicke, Charles G. Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt

Blood (2024) 143 (24): 2474–2489.

https://doi.org/10.1182/blood.2023022655

Published: 2024

Includes: Supplemental data

Journal Articles

Single Cell Transcriptomic Analysis of B-Cell Acute Lymphoblastic Leukemia (B-ALL) Reveals Correlation between Leukemia Cell State, Genetic Alterations and Clinical Outcome

Ilaria Iacobucci, Andy G.X. Zeng, Qingsong Gao, Laura Garcia Prat, Pradyumna Baviskar, Sayyam Shah, Alexander Murison, Veronique Voisin, Colin Bailey, Matthew Lear, Anjali S. Advani, Selina M Luger, Elisabeth Paietta, Wendy Stock, John E. Dick, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 841.

https://doi.org/10.1182/blood-2023-190180

Published: 2023

NARROW

Revolutionizing B-ALL Cell Line Development: Novel Generation to Uncover Therapeutic Vulnerabilities

Lessons Learned from Mapping the Process of De-Implementation of Routine Cytogenetics in the Diagnosis of Pediatric Acute Lymphoblastic Leukemia

The Histone Acetyltransferase MOZ (KAT6A) Is a Molecular Dependency and Therapeutic Target in NUP98 -Rearranged Acute Myeloid Leukemia

Differential Role of Crebbp Missense and Truncating Mutations in the Malignant Transformation of Germinal Center B Cells

Refined Immunophenotypic Criteria Using CD184 and CD165 Improves Sensitivity of Identification of ETP T-ALL

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Inhibiting Free Fatty Acid Transport to Improve CAR-T Cell Therapy of Relapsed B-Cell Acute Lymphoblastic Leukemia

A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Safety and Feasibility of Blinatumomab As Frontline Therapy for Pediatric Patients with B-Acute Lymphoblastic Leukemia and Lymphoma: St. Jude Total Therapy Study XVII

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

Impact of Ph-like Gene Signatures on Clinical Outcomes in Adult B-ALL Patients in Resource-Constrained Settings

Classification and risk stratification in T-lineage acute lymphoblastic leukemia

Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Single Cell Transcriptomic Analysis of B-Cell Acute Lymphoblastic Leukemia (B-ALL) Reveals Correlation between Leukemia Cell State, Genetic Alterations and Clinical Outcome

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American Society of Hematology

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ASH Publications

American Society of Hematology

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