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Journal Articles

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Masayuki Umeda, Nicole L Michmerhuizen, Ryan Hiltenbrand, Juan M Barajas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover, Petri Pölönen, Cristina Mecucci, Danika Di Giacomo, Franco Locatelli, Riccardo Masetti, Salvatore Bertuccio, Martina Pigazzi, Ilaria Iacobucci, Charles G. Mullighan, Jeffery M Klco

Blood (2024) 144 (Supplement 1): 325.

https://doi.org/10.1182/blood-2024-210208

Published: 2024

Journal Articles

CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia

Blood (2024) 144 (Supplement 1): 2076.

https://doi.org/10.1182/blood-2024-208795

Published: 2024

Journal Articles

The Histone Acetyltransferase MOZ (KAT6A) Is a Molecular Dependency and Therapeutic Target in NUP98 -Rearranged Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 825.

https://doi.org/10.1182/blood-2024-210529

Published: 2024

Journal Articles

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery M Klco, Alan S Gamis, Rhonda E. Ries, Anders Kolb, Richard Aplenc, Todd A. Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 103.

https://doi.org/10.1182/blood-2024-207665

Published: 2024

Journal Articles

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

Masahiro Uni, Asher Preska Steinberg, Alicia Slavit, Sophia Rha, Shuyuan Cheng, Laura K. Schmalbrock, Jiayu Su, Jing Ma, Andrew McPherson, Charles G. Mullighan, Torsten Haferlach, Ilaria Iacobucci, Jeffery M Klco, Raul Rabadan, Alex Kentsis

Blood (2024) 144 (Supplement 1): 4149.

https://doi.org/10.1182/blood-2024-200137

Published: 2024

Journal Articles

Oncogenic Potential and Sensitivity to Menin Inhibitors of a Novel Fusion KAT6B::NUTM2B in Congenital Myeloid Sarcoma with Bone Marrow Involvement

Rebecca Voss, Wenqing Qi, Yen-Chun Liu, Jing Ma, La'Ron Browne, Mahsa Khanlari, Juan M Barajas, Melvin Thomas, III, Victor B Pastor Loyola, Hui Cao, Seth E. Karol, Jeffrey E. Rubnitz, Jeffery M Klco, Lu Wang

Blood (2024) 144 (Supplement 1): 1352.

https://doi.org/10.1182/blood-2024-208358

Published: 2024

Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Blood (2024) 143 (7): 619–630.

https://doi.org/10.1182/blood.2023021359

Published: 2024

Includes: Supplemental data

Journal Articles

Preliminary Safety and Efficacy of Venetoclax and Selinexor in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed or Refractory Acute Myeloid Leukemia: Selclax

Sara Zarnegar-Lumley, Seth E. Karol, Stanley Pounds, Jeffery M. Klco, Maria Luisa Sulis, Dennis John Kuo, Kenneth Matthew Heym, Kathleen Ludwig, Alexandra McLean Stevens, Thomas B. Alexander, Kelly Elizabeth Faulk, Himalee S. Sabnis, Sarah K. Tasian, Jeffrey Taub, Andrew E. Place, Jeffrey E. Rubnitz

Blood (2023) 142 (Supplement 1): 56.

https://doi.org/10.1182/blood-2023-174342

Published: 2023

Journal Articles

UBTF Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis

Juan Barajas, Masayuki Umeda, Jing Ma, Mahsa Khanlari, Michael P Walsh, Tamara Westover, Lisett Contreras, Guangchun Song, Xiaotu Ma, Melvin Thomas, III, Jeffery M. Klco

Blood (2023) 142 (Supplement 1): 838.

https://doi.org/10.1182/blood-2023-172765

Published: 2023

Journal Articles

Identification and Functional Validation of Neoantigen-Specific T Cells in Pediatric Patients with Fusion-Derived Acute Leukemias

Ricky Tirtakusuma, Mohamed A. Ghonim, Stefan Schattgen, Jing Ma, Brad Muller, Kasi Vegesana, Emma Allen, Jeffery M. Klco, Paul G. Thomas

Blood (2023) 142 (Supplement 1): 2074.

https://doi.org/10.1182/blood-2023-184918

Published: 2023

Journal Articles

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Masayuki Umeda, Nicole Michmerhuizen, Ryan Hiltenbrand, Juan Barajas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover, Cristina Mecucci, Danika Di Giacomo, Franco Locatelli, Riccardo Masetti, Salvatore Bertuccio, Martina Pigazzi, Ilaria Iacobucci, Charles G. Mullighan, Jeffery M. Klco

Blood (2023) 142 (Supplement 1): 1562.

https://doi.org/10.1182/blood-2023-184622

Published: 2023

Journal Articles

Cancer Genomic Profiling and Minimal Residual Disease Monitoring By Cell-Free DNA Sequencing in Pediatric Leukemia

Shaohua Lei, Sujuan Jia, Sunitha Takalkar, Ti-Cheng Chang, Gang Wu, Xiaotu Ma, Selene C. Koo, Paul E. Mead, Jeffery M. Klco, Ruth G. Tatevossian, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 1604.

https://doi.org/10.1182/blood-2023-188158

Published: 2023

Journal Articles

Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions

Blood (2023) 141 (7): 800–805.

https://doi.org/10.1182/blood.2022017874

Published: 2023

Includes: Supplemental data

Journal Articles

Engineering naturally occurring CD7 − T cells for the immunotherapy of hematological malignancies

Blood (2022) 140 (25): 2684–2696.

https://doi.org/10.1182/blood.2021015020

Published: 2022

Includes: Supplemental data

Journal Articles

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Blood (2022) 140 (21): 2228–2247.

https://doi.org/10.1182/blood.2022015853

Published: 2022

Includes: Supplemental data

Journal Articles

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Anna L. Brown, Claire Homan, Michael W. Drazer, Kai Yu, David Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew Pozsgai, Kelsey McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah King-Smith, Jesse JC Cheah, Mark Armstrong, Csaba Bödör, Paul Wang, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Young Rienhoff, Jr., Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Deolinda Rodrigues Pereira Velloso, Benedict Yan, Raman Sood, Amy Hsu, Steven M. Holland, Kerry Phillips, Nicola Poplawski, Milena Babic, Erika M Kwon Kim, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D Lewis, Julian Cooney, Rachel Susman, Lucy C Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Andreas W Schreiber, Christopher N Hahn, Hamish S Scott, Paul P. Liu, Lucy A. Godley

Blood (2022) 140 (Supplement 1): 4030–4033.

https://doi.org/10.1182/blood-2022-167600

Published: 2022

Journal Articles

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

Tamara Westover, Sherif Abdelhamed, Emily Xiong, Michael P Walsh, Jing Ma, Jasmine C. Wong, Astrid Behnert, Mignon L. Loh, Kevin M. Shannon, Jeffery M. Klco

Blood (2022) 140 (Supplement 1): 5837–5838.

https://doi.org/10.1182/blood-2022-166915

Published: 2022

Journal Articles

Human Models of NUP98 -Rearranged Leukemia Reveal Fusion-Specific Molecular Mechanisms

Masayuki Umeda, Nicole L. Michmerhuizen, Ryan Hiltenbrand, Juan M. Barajas, Bright Arthur, Sherif Abdelhamed, Jing Ma, Tamara Westover, Jonathan Miller, Charles G. Mullighan, Jeffery M. Klco

Blood (2022) 140 (Supplement 1): 5833–5834.

https://doi.org/10.1182/blood-2022-164686

Published: 2022

Journal Articles

Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche

Sarah E. Moore, Jaquelyn T. Zoine, Jeremy Chase Crawford, Deanna Langfitt, Juan M. Barajas, Sherif Abdelhamed, Ilaria Iacobucci, Dalia Haydar, Giedre Krenciute, Charles G. Mullighan, Jeffery M. Klco, Stephen Gottschalk, Paul G. Thomas, Mireya Paulina Velasquez

Blood (2022) 140 (Supplement 1): 7376–7377.

https://doi.org/10.1182/blood-2022-169800

Published: 2022

Journal Articles

UBTF -TD Expression Is Necessary and Sufficient for Myeloid Cell Expansion

Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Masayuki Umeda, Ryan Hiltenbrand, Bright Arthur, Reethu Krishnan, Michael P Walsh, Jing Ma, Jeffery M. Klco

Blood (2022) 140 (Supplement 1): 8733–8734.

https://doi.org/10.1182/blood-2022-159628

Published: 2022

NARROW

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia

The Histone Acetyltransferase MOZ (KAT6A) Is a Molecular Dependency and Therapeutic Target in NUP98 -Rearranged Acute Myeloid Leukemia

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

Oncogenic Potential and Sensitivity to Menin Inhibitors of a Novel Fusion KAT6B::NUTM2B in Congenital Myeloid Sarcoma with Bone Marrow Involvement

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Preliminary Safety and Efficacy of Venetoclax and Selinexor in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed or Refractory Acute Myeloid Leukemia: Selclax

UBTF Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis

Identification and Functional Validation of Neoantigen-Specific T Cells in Pediatric Patients with Fusion-Derived Acute Leukemias

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Cancer Genomic Profiling and Minimal Residual Disease Monitoring By Cell-Free DNA Sequencing in Pediatric Leukemia

Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions

Engineering naturally occurring CD7 − T cells for the immunotherapy of hematological malignancies

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

Human Models of NUP98 -Rearranged Leukemia Reveal Fusion-Specific Molecular Mechanisms

Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche

UBTF -TD Expression Is Necessary and Sufficient for Myeloid Cell Expansion

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American Society of Hematology

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American Society of Hematology

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