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Journal Articles

Identification of Interstitial Loss of Heterozygosity (LOH) Regions Flanking CD33 Locus in AML Patients

Vivek M. Shastri, Francisco Marchi, Michael R. Loken, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 1543.

https://doi.org/10.1182/blood-2024-211258

Published: 2024

Journal Articles

Genome-Wide Association Study Identifies Variants Predictive of Febrile Neutropenia during Induction I in Newly Diagnosed Pediatric Acute Myeloid Leukemia Patients

Satyavardhan Rao Nittu, Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 6110.

https://doi.org/10.1182/blood-2024-208130

Published: 2024

Journal Articles

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery M Klco, Alan S Gamis, Rhonda E. Ries, Anders Kolb, Richard Aplenc, Todd A. Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 103.

https://doi.org/10.1182/blood-2024-207665

Published: 2024

Journal Articles

Synergistic Effect of Trifluridine and PARPi Combination in Targeting TP53 -Mutated AML

Phani Krishna Parcha, Vivek M. Shastri, Jonathan D. Licht, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 5787.

https://doi.org/10.1182/blood-2024-201781

Published: 2024

Journal Articles

CDKN2A Upregulation Induces Senescence in AML Cell Lines and Leads to Treatment Resistance

Vivek M. Shastri, Nathan Seligson, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 5741.

https://doi.org/10.1182/blood-2024-208173

Published: 2024

Journal Articles

Gene Expression Profiling in Pediatric AML Patients with Febrile Neutropenia during Induction Therapy

Satyavardhan Rao Nittu, Nam Nguyen, Jim Wang, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Anders Kolb, Soheil Meshinchi, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 6119.

https://doi.org/10.1182/blood-2024-210446

Published: 2024

Journal Articles

Genome-Wide Association Study of Metabolites in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia Identified Novel Metabolite Quantitative Trait Loci

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 4327.

https://doi.org/10.1182/blood-2024-193819

Published: 2024

Journal Articles

GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin M. Guest, Carol Hwang Lin, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 2846.

https://doi.org/10.1182/blood-2024-208260

Published: 2024

Journal Articles

Immunotherapeutic Potential and In Vivo Targeting of CD33 Splice Variant Isoform

Vivek M. Shastri, Srideshikan Sargur Madabushi, Susanta Hui, Jatinder K. Lamba

Blood (2024) 144 (Supplement 1): 1394.

https://doi.org/10.1182/blood-2024-208496

Published: 2024

Journal Articles

Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia

Onyee Chan, Kendra L. Sweet, Chetasi Talati, Fatima Tuz Zahra, Lisa Ann Nardelli, Jatinder K. Lamba, Jongphil Kim, Jinming Song, Zhuoer Xie, Seongseok Yun, Andrew T. Kuykendall, Eric Padron, Alison R. Walker, Rami S. Komrokji, Jeffrey E Lancet, David Sallman

Blood (2024) 144 (Supplement 1): 4270.

https://doi.org/10.1182/blood-2024-206161

Published: 2024

Journal Articles

Pharmacogenomics to Predict Asparaginase Premedication-Related Hypersensitivity in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Yeniffer Nunez, Sonia Morales, Anurag Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 6067.

https://doi.org/10.1182/blood-2023-187111

Published: 2023

Journal Articles

ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients

Richard J Marrero, Vivek M. Shastri, Richard Aplenc, Todd Cooper, Todd A. Alonzo, Alan S Gamis, Jim Wang, Soheil Meshinchi, E. Anders Kolb, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 4314.

https://doi.org/10.1182/blood-2023-187515

Published: 2023

Journal Articles

A DNA Methylation Signature Predicts Clinical Outcome in Pediatric AML Patients

Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 835.

https://doi.org/10.1182/blood-2023-186505

Published: 2023

Journal Articles

GWAS Identifies Variants Associated with Minimal Residual Disease after Induction I in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 2967.

https://doi.org/10.1182/blood-2023-179946

Published: 2023

Journal Articles

Splicing Polymorphism rs12459419 Modulates Antibody-Bound Internalization of CD33 Isoforms

Vivek M. Shastri, Mohammed O. Gbadamosi, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 5749.

https://doi.org/10.1182/blood-2023-186889

Published: 2023

Journal Articles

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Nam Nguyen, Phani Krishna Parcha, Abderrahmane Tagmount, Bailey Gregory, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Todd Cooper, E. Anders Kolb, Soheil Meshinchi, Stanley Pounds, Christopher Vulpe, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 1558.

https://doi.org/10.1182/blood-2023-178832

Published: 2023

Journal Articles

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Jatinder K. Lamba, Richard J Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Seth E. Karol, Hiroto Inaba, Dennis John Kuo, Barbara Degar, Kenneth Matthew Heym, Jeffrey Taub, Norman J. Lacayo, Ching-Hon Pui, Raul C. Ribeiro, Stanley Pounds, Jeffrey E. Rubnitz

Blood (2023) 142 (Supplement 1): 386.

https://doi.org/10.1182/blood-2023-173617

Published: 2023

Journal Articles

Impact of Cytarabine Pharmacogenomics on Survival of Adolescent and Young Adults with AML and Its Clinical Relevance in Black Patients

Richard J Marrero, Deedra Nicolet, Vivek M. Shastri, Krzysztof Mrózek, Christopher J. Walker, William Blum, Bayard L Powell, Jonathan E Kolitz, Joseph O Moore, Geoffrey L Uy, Wendy Stock, Andrew J Carroll, John C. Byrd, Ann-Kathrin Eisfeld, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 2954.

https://doi.org/10.1182/blood-2023-187361

Published: 2023

Journal Articles

The Methylome Atlas of Acute Leukemia Enables Novel Clinical Diagnostic Tool for AML

Blood (2023) 142 (Supplement 1): 121.

https://doi.org/10.1182/blood-2023-186894

Published: 2023

Journal Articles

Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric Acute Myeloid Leukemia

Satyavardhan Rao Nittu, Francisco Marchi, Nam Nguyen, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Jeffery Klco, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 2926.

https://doi.org/10.1182/blood-2023-189029

Published: 2023

NARROW

Identification of Interstitial Loss of Heterozygosity (LOH) Regions Flanking CD33 Locus in AML Patients

Genome-Wide Association Study Identifies Variants Predictive of Febrile Neutropenia during Induction I in Newly Diagnosed Pediatric Acute Myeloid Leukemia Patients

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Synergistic Effect of Trifluridine and PARPi Combination in Targeting TP53 -Mutated AML

CDKN2A Upregulation Induces Senescence in AML Cell Lines and Leads to Treatment Resistance

Gene Expression Profiling in Pediatric AML Patients with Febrile Neutropenia during Induction Therapy

Genome-Wide Association Study of Metabolites in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia Identified Novel Metabolite Quantitative Trait Loci

GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Immunotherapeutic Potential and In Vivo Targeting of CD33 Splice Variant Isoform

Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia

Pharmacogenomics to Predict Asparaginase Premedication-Related Hypersensitivity in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients

A DNA Methylation Signature Predicts Clinical Outcome in Pediatric AML Patients

GWAS Identifies Variants Associated with Minimal Residual Disease after Induction I in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Splicing Polymorphism rs12459419 Modulates Antibody-Bound Internalization of CD33 Isoforms

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Impact of Cytarabine Pharmacogenomics on Survival of Adolescent and Young Adults with AML and Its Clinical Relevance in Black Patients

The Methylome Atlas of Acute Leukemia Enables Novel Clinical Diagnostic Tool for AML

Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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