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Journal Articles

GWAS-guided pharmacogenomic risk scores predict premedication-related pegaspargase hypersensitivity and toxicities in pediatric and adolescent young adults with acute lymphoblastic leukemia or lymphoma

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Vivek Shastri, Sonia Morales, Anurag Agrawal, Christine Phillips, Keith August, Erin Guest, Carol Lin, Beth Apsel Winger, Catherine Aftandilian, Van Huynh, Jatinder Lamba
Journal: Blood
Blood (2025) 146 (Supplement 1): 6881.
https://doi.org/10.1182/blood-2025-6881
Published: 2025
Journal Articles

Pharmacogenetic variants in UGT1A1/UGT1A3 and ABCC2 associate with deferasirox efficacy in transfusion-dependent thalassemia.

Free
Chandni Patel, Vivek Shastri, Janel Long-Boyle, Johnny Li, Felicity Rose, Beth Apsel Winger, Jatinder Lamba
Journal: Blood
Blood (2025) 146 (Supplement 1): 1140.
https://doi.org/10.1182/blood-2025-1140
Published: 2025
Journal Articles

ReInspire: A phase 2 study of mutant-selective PI3Kα inhibitor, RLY-2608, in adults and children with PIK3CA-related overgrowth spectrum and malformations driven by PIK3CA mutation

Free
Shelley Crary, Joana Mack, Ahmad Al-Huniti, Vivian Chang, Beth Drolet, Adrienne Hammill, Ionela Iacobas, Michael Kelly, Beth Apsel Winger, Martin Robledo, Rick Blakesley, Caitlin Patriquin, Brenton Mar, Bryan Sisk
Journal: Blood
Blood (2025) 146 (Supplement 1): 3092.
https://doi.org/10.1182/blood-2025-3092
Published: 2025
Journal Articles

GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Free
Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin M. Guest, Carol Hwang Lin, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 2846.
https://doi.org/10.1182/blood-2024-208260
Published: 2024
Journal Articles

Asparaginase-Associated Toxicities and Hypersensitivity Reactions in Pediatric and Adolescent Down Syndrome Patients with Acute Lymphoblastic Leukemia or Lymphoma

Free
Van Thu Huynh, Carol Hwang Lin, Sonia Morales, Anurag K. Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Janel R. Long-Boyle, Kirsten Kasper, Keri Zabokrtsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 5809.
https://doi.org/10.1182/blood-2023-190734
Published: 2023
Journal Articles

Pharmacokinetics (PK) of Deferasirox in Transfusion Dependent Thalassemia

Free
Beth Apsel Winger, Felicity Usac, Liusheng Huang, Ashutosh Lal, Janel R. Long-Boyle
Journal: Blood
Blood (2023) 142 (Supplement 1): 5248.
https://doi.org/10.1182/blood-2023-188405
Published: 2023
Journal Articles

Pharmacogenomics to Predict Asparaginase Premedication-Related Hypersensitivity in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Free
Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Yeniffer Nunez, Sonia Morales, Anurag Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 6067.
https://doi.org/10.1182/blood-2023-187111
Published: 2023
Journal Articles

Premedication and Therapeutic Drug Monitoring (TDM) for Pegaspargase: A Prospective Multicenter Multi-Ethnic Study of Pediatric and Adolescent Patients

Free
Van T Huynh, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin Guest, Beth Apsel Winger, Catherine Aftandilian, Janel R. Long-Boyle, Kirsten Kasper, Keri Zabokrtsky, Carol Hwang Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8893–8895.
https://doi.org/10.1182/blood-2022-159255
Published: 2022
Journal Articles

Pharmacogenomics of Fludarabine in Pediatric HCT Recipients: Preliminary Results

Free
Nam H.K. Nguyen, Vivek M. Shastri, Ying Lu, Beth Apsel Winger, Janel R. Long-Boyle, Biljana N. Horn, Jatinder K. Lamba
Journal: Blood
Blood (2021) 138 (Supplement 1): 908.
https://doi.org/10.1182/blood-2021-151457
Published: 2021
Journal Articles

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-Risk Leukemias: A Report from the LEAP Consortium

Free
Yana Pikman, MD, Sarah K. Tasian, MD, Maria Luisa Sulis, MD, Todd M Cooper, DO, Melinda Pauly, MD, Kelly W. Maloney, MD, Michael J. Burke, MD, Patrick Brown, MD, Nathan Gossai, MD, Peter Cole, MD, Jennifer McNeer, MD MS, Neerav Shukla, MD, Beth Apsel Winger, MD PhD, Asmani A Adhav, Traci M. Blonquist, MS, Amy Conway, Andrew E. Place, MD PhD, Lia Gore, MD, Stephen P. Hunger, MD, Katherine Janeway, MD MMSc, Lewis B. Silverman, MD, Jeffrey W. Tyner, PhD, Marian H. Harris, MD PhD, Mignon L. Loh, MD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 261.
https://doi.org/10.1182/blood-2018-99-116948
Published: 2018