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Christine L Phillips
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Journal Articles

Role of B Cell Recovery in Relapse Risk and CD19 Phenotype Following Real-World Use of Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia: A Multi-Institutional Retrospective Study

Xiaopei Lily Zeng, Soyang Kwon, Anant Vatsayan, Christina Baggott, Snehit Prabhu, Samuel John, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas D. Myers, Erin Marie Hall, Nicole A Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K Keating, Susanne H.C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Khanh Nguyen, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Kevin O. McNerney
Journal: Blood
Blood (2024) 144 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2024-211231
Published: 2024
Journal Articles

Impact of Extramedullary Disease on the Outcomes after Allogeneic Hematopoietic Cell Transplantation in Children and Young Adults with Acute Myeloid Leukemia - a CIBMTR Analysis

Hemalatha Rangarajan, Deepak Chellapandian, Rasha Atshan, Kwang Wooahn, Akshay Sharma, Kirk R. Schultz, Parinda A. Mehta, Christine L. Phillips, Larisa Broglie, Prakash Satwani
Journal: Blood
Blood (2024) 144 (Supplement 1): 2412.
https://doi.org/10.1182/blood-2024-201848
Published: 2024
Journal Articles

Real World Comparison of Efficacy and Safety of Fludarabine-Versus Bendamustine-Based Lymphodepleting Chemotherapy for CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy in Relapse/Refractory (r/r) Large B-Cell Lymphoma (LBCL)

Alaa Ali, Nausheen Ahmed, Soyoung Kim, Matthew Bye, Sayeef Mirza, Alex Gordon Sieg, Christopher Strouse, Kalyan Nadiminti, Priyanka A. Pophali, Rammurti T. Kamble, Lohith Gowda, Cameron J. Turtle, Christine L. Phillips, Marcelo C. Pasquini, Sairah Ahmed, Siddhartha Ganguly, Amy Moskop
Journal: Blood
Blood (2024) 144 (Supplement 1): 71.
https://doi.org/10.1182/blood-2024-200269
Published: 2024
Journal Articles

Impact of Current Manufacturing on Kymriah Real-World Effectiveness and Functional Persistence in Acute Lymphoblastic Leukemia (ALL) (KareALL): A Retrospective Study of Tisagenlecleucel (tisa-cel)-Treated Pediatric and Young Adult Patients (pts) with ALL

Rayne Rouce, J. Gregory Dolan, Christine L. Phillips, Muna Qayed, Michael A. Pulsipher, Lauren M. Vernau, Thomas J. Galletta, Sarah Votaw, Gabriela Llaurador Caraballo, Hongbo Yang, Yao Wang, Shashank Ghantoji, Mimi Tesfaye, Soyon Lee, Emer O'Sullivan, Stephan A. Grupp
Journal: Blood
Blood (2024) 144 (Supplement 1): 7724.
https://doi.org/10.1182/blood-2024-203376
Published: 2024
Journal Articles

GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin M. Guest, Carol Hwang Lin, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 2846.
https://doi.org/10.1182/blood-2024-208260
Published: 2024
Journal Articles

Itacitinib for the Prevention of Immune Effector Cell Therapy-Associated Cytokine Release Syndrome: Results from the Phase 2 Incb 39110-211 Placebo-Controlled Randomized Cohort

Matthew J. Frigault, Richard T Maziarz, Jae H. Park, Aleksandr Lazaryan, Nirav N. Shah, Jakub Svoboda, Lazaros J. Lekakis, Ran Reshef, Christine L Phillips, Lea M Burke, Jing Lei, Rodica Morariu-Zamfir, John F. DiPersio
Journal: Blood
Blood (2023) 142 (Supplement 1): 356.
https://doi.org/10.1182/blood-2023-180205
Published: 2023
Journal Articles

Risk Factors and Outcomes for Hematotoxicity Following Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia

Kevin O. McNerney, Vanessa A. Fabrizio, Aimee C. Talleur, Stephanie Si Lim, Alexandra Dreyzin, Christina Baggott, Anant Vatsayan, Jenna Rossoff, Snehit Prabhu, Holly L. Pacenta, Christine L Phillips, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas Myers, Nicole Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy Keating, Susanne H.C. Baumeister, Vasant Chinnabhandar, Emily Egeler, Kevin J Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Swati Naik
Journal: Blood
Blood (2023) 142 (Supplement 1): 2133.
https://doi.org/10.1182/blood-2023-189921
Published: 2023
Journal Articles

Pharmacogenomics to Predict Asparaginase Premedication-Related Hypersensitivity in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Yeniffer Nunez, Sonia Morales, Anurag Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 6067.
https://doi.org/10.1182/blood-2023-187111
Published: 2023
Journal Articles

Asparaginase-Associated Toxicities and Hypersensitivity Reactions in Pediatric and Adolescent Down Syndrome Patients with Acute Lymphoblastic Leukemia or Lymphoma

Van Thu Huynh, Carol Hwang Lin, Sonia Morales, Anurag K. Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Janel R. Long-Boyle, Kirsten Kasper, Keri Zabokrtsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 5809.
https://doi.org/10.1182/blood-2023-190734
Published: 2023
Journal Articles

Establishing Costs for Commercial Chimeric Antigen Receptor T-Cell (Tisagenlecleucel; Kymriah) in Children and Young Adult B-Cell Acute Lymphoblastic Leukemia; A Merged Analysis from the Prwcc and PHIS

Prakash Satwani, Karen Chao, Maria Lopez-Garcia, Matt Hall, Zhezhen Jin, Lena E Winestone, Danielle Novetsky Friedman, Rachel Phelan, Christina Baggott, Samuel John, Holly L. Pacenta, Theodore W. Laetsch, Christine L Phillips, Michael R Verneris, Vanessa A. Fabrizio, Amy Keating, Julie-An Talano, Amy Moskop, Susanne H.C. Baumeister, Muna Qayed, Doug Douglas Myers, Erin Marie Hall, Snehit Prabhu, Khanh Nguyen, Casey A Carr, Crystal L. Mackall, John K Lin, Jeremy Goldhaber-Fiebert, Liora Michal Schultz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6912.
https://doi.org/10.1182/blood-2023-187462
Published: 2023
Journal Articles

Premedication and Therapeutic Drug Monitoring (TDM) for Pegaspargase: A Prospective Multicenter Multi-Ethnic Study of Pediatric and Adolescent Patients

Van T Huynh, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin Guest, Beth Apsel Winger, Catherine Aftandilian, Janel R. Long-Boyle, Kirsten Kasper, Keri Zabokrtsky, Carol Hwang Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8893–8895.
https://doi.org/10.1182/blood-2022-159255
Published: 2022
Journal Articles

Peripheral Blast Count at Apheresis Acts Independent of Disease Burden As a Risk Factor for Survival Following Tisagenlecleucel in Children and Young Adults

Vanessa A. Fabrizio, Kristen Miller, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie Talano, Amy Moskop, Susanne H.C. Baumeister, Gary Douglas Myers, Nicole Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Rachel Wilcox, Vasant Chinnabhandar, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Amy K. Keating, Michael R. Verneris, Liora M. Schultz
Journal: Blood
Blood (2022) 140 (Supplement 1): 4661–4663.
https://doi.org/10.1182/blood-2022-169603
Published: 2022
Journal Articles

Out-of-specification tisagenlecleucel does not compromise safety or efficacy in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Jenna Rossoff, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine L. Phillips, Heather Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Gary Douglas Myers, Nicole Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Michael Kunicki, Vasant Chinnabhandar, A. Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz
Journal: Blood
Blood (2021) 138 (21): 2138–2142.
https://doi.org/10.1182/blood.2021012392
Published: 2021
Journal Articles

Real-World Outcomes for Pediatric and Young Adult Patients with Relapsed or Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (ALL) Treated with Tisagenlecleucel: Update from the Center for International Blood and Marrow Transplant Research (CIBMTR) Registry

Samuel John, Michael A. Pulsipher, Amy Moskop, Zhen-Huan Hu, Christine L. Phillips, Erin Marie Hall, Steven P. Margossian, Sarah Nikiforow, Paul L. Martin, Benjamin Oshrine, Amy K. Keating, Rayne H. Rouce, Ranjan Tiwari, Santiago Redondo, Jennifer Willert, Abhijit Agarwal, Marcelo C Pasquini, Stephan A. Grupp
Journal: Blood
Blood (2021) 138 (Supplement 1): 428.
https://doi.org/10.1182/blood-2021-146393
Published: 2021
Journal Articles

HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia

Michael W Boyer, MD, Sonali Chaudhury, MBBS,MD, Kara L Davis, DO, Timothy Alan Driscoll, MD, Stephan A Grupp, MD PhD, Michelle Hermiston, MD PhD, Samuel John, MD, Amy K Keating, MD PhD, Christina Kovacs, BS, JD, Andrea Magley, BS, Gary Douglas Myers, MD, Christine L Phillips, MD, Michael A Pulsipher, MD, Das Purkayastha, PhD, Julie-An Talano, MD, Jennifer Willert, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-136340
Published: 2020
Journal Articles

Disease Burden Impacts Outcomes in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia after Commercial Tisagenlecleucel: Results from the Pediatric Real World CAR Consortium (PRWCC)

Liora M. Schultz, MD, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine L Phillips, MD, Jenna Rossoff, MD, Heather Stefanski, MDPhD, Julie-An Talano, MD, Amy Moskop, MD, Steven P. Margossian, MD PhD, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Patrick A. Brown, MD, Muna Qayed, MDMSc, Michelle Hermiston, MD PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy Keating, MD, Rachel Wilcox, Cara A Rabik, MDPhD, Vanessa Fabrizio, MD, Michael Kunicki, Vasant Chinnabhandar, MD, A. Yasemin Goksenin, MD PhD MA, MPH, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-134472
Published: 2020
Journal Articles

Real-World Treatment of Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Using Tisagenlecleucel That Is out of Specification for Commercial Release

Jenna Rossoff, MD, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine L Phillips, MD, Heather Stefanski, MDPhD, Julie-An Talano, MD, Amy Moskop, MD, Steven P. Margossian, MD PhD, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Patrick A. Brown, MD, Muna Qayed, MDMSc, Michelle Hermiston, MD PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy Keating, MD, Rachel Wilcox, Cara A Rabik, MDPhD, Vanessa Fabrizio, MD, Michael Kunicki, Vasant Chinnabhandar, MD, A. Yasemin Goksenin, MD PhD MA, MPH, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Liora M. Schultz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-136674
Published: 2020
Journal Articles

V2 Trial: A Phase I Study of Venetoclax Combined with CPX-351 for Children, Adolescents and Young Adults with Relapsed or Refractory Acute Leukemia

Laura Agresta, MD, Maureen M O'Brien, MD, Kana Mizuno, PhD, Robin Norris, MD MS, MPH, Erin H. Breese, MD PhD, Christine L Phillips, MD, Karen Burns, MD, Benjamin Mizukawa, Lynn Lee, MD, Adam Lane, PhD, Robert B. Lorsbach, MD PhD, Thomas D. Ryan, MD PhD, Pankaj B. Desai, PhD, Alexander A. Vinks, PharmD, PhD, H. Leighton Grimes, PhD, John P Perentesis, Michael J. Absalon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3830.
https://doi.org/10.1182/blood-2019-121514
Published: 2019
Journal Articles

A Phase I/Pilot Study of CPX-351 [Daunorubicin and Cytarabine Liposome for Injection (Vyxeos®)] for Children, Adolescents and Young Adults with Recurrent or Refractory Acute Leukemia

Michael J. Absalon, MD PhD, Erin H. Breese, MD PhD, Lynn Lee, MD, Maureen M O'Brien, MD MS, Christine L Phillips, MD, Karen Burns, MD, Benjamin Mizukawa, MD, Qi An, Jennifer Mangino, MD, Joel Kaplan, DO, Robin Norris, MD, John Peter Perentesis, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 336.
https://doi.org/10.1182/blood-2018-99-119618
Published: 2018
Journal Articles

Exceptional Responses to Epigenetic Based Therapy in Pediatric and Young Adult Monosomy 7 MDS/AML Patients with and without TP53 Mutations

LaQuita M Jones, DO, Maureen M O'Brien, MD, Erin H. Breese, MD PhD, Karen Burns, MD, Jennifer Mangino, MD, Michael J. Absalon, MD PhD, Javier A. El-Bietar, MD, Michael Grimley, MD, Benjamin Mizukawa, MD, Lynn Lee, MD, John Peter Perentesis, MD, Christine L Phillips, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3895.
https://doi.org/10.1182/blood.V130.Suppl_1.3895.3895
Published: 2017