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Erin M. Guest
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Journal Articles

Proteomic Characterization of Pediatric Acute Lymphoblastic Leukemias Sheds Light on Subtype-Specific Molecular Mechanisms

Irina Pushel, Zachary Clark, Michaella J Rekowski, Lisa A Lansdon, Byunggil Yoo, Keith J August, Alan S Gamis, Erin M. Guest, Michael P Washburn, Midhat S Farooqi
Journal: Blood
Blood (2024) 144 (Supplement 1): 5920.
https://doi.org/10.1182/blood-2024-208937
Published: 2024
Journal Articles

A Retrospective Study of Inotuzumab Ozogamicin in Individuals with Down Syndrome and B-Cell Acute Lymphoblastic Leukemia

Amanda M Li, Catherine Aftandilian, Susan Colace, Sarah Fanizzi, Kelly Elizabeth Faulk, Erin M. Guest, Ammar Hayani, Richard Ho, Anjali Khanna, Kasey Leger, David McCall, Tamara P. Miller, Holly Pacenta, Troy Quigg, Jeremy D. Rubinstein, Deepa Bhojwani, Susan R Rheingold, Maureen M. O'Brien, Karen R Rabin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4204.
https://doi.org/10.1182/blood-2024-209455
Published: 2024
Journal Articles

GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Sonia Morales, Anurag K. Agrawal, Christine L. Phillips, Keith J August, Erin M. Guest, Carol Hwang Lin, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 2846.
https://doi.org/10.1182/blood-2024-208260
Published: 2024
Journal Articles

A Genomics Driven, Inducible Pluripotent Stem Cell Model of Infant Lymphoblastic Leukemia

Meagan Vacek, Jacqelyn Nemechek, Irina Pushel, Bradley Thornton, Molly Leyda, Priyanka Prem Kumar, Midhat S Farooqi, Erin M. Guest, Jay Vivian, John M. Perry
Journal: Blood
Blood (2024) 144 (Supplement 1): 1369.
https://doi.org/10.1182/blood-2024-205922
Published: 2024
Journal Articles

Pharmacogenomics to Predict Asparaginase Premedication-Related Hypersensitivity in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma

Vivek M. Shastri, Jennifer Ahmed, Eva Spin, Yeniffer Nunez, Sonia Morales, Anurag Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Van Thu Huynh, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 6067.
https://doi.org/10.1182/blood-2023-187111
Published: 2023
Journal Articles

Asparaginase-Associated Toxicities and Hypersensitivity Reactions in Pediatric and Adolescent Down Syndrome Patients with Acute Lymphoblastic Leukemia or Lymphoma

Van Thu Huynh, Carol Hwang Lin, Sonia Morales, Anurag K. Agrawal, Christine L Phillips, Keith J. August, Erin M. Guest, Beth Apsel Winger, Catherine Aftandilian, Janel R. Long-Boyle, Kirsten Kasper, Keri Zabokrtsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 5809.
https://doi.org/10.1182/blood-2023-190734
Published: 2023
Journal Articles

Trajectory Inference Highlights Dynamic Expression of T-Cell Development Genes in Pediatric T-Cell Acute Lymphoblastic Leukemia

Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Erin M. Guest, Midhat S Farooqi, Keith J. August
Journal: Blood
Blood (2023) 142 (Supplement 1): 2983.
https://doi.org/10.1182/blood-2023-187434
Published: 2023
Journal Articles

Single-Cell RNA Sequencing Facilitates Study of Cancer Mechanisms across Pediatric Leukemias

Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Alan S Gamis, Keith J. August, Terrie Flatt, Tomi Pastinen, Erin M. Guest, Midhat S Farooqi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1614.
https://doi.org/10.1182/blood-2023-187340
Published: 2023
Journal Articles

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A -rearranged leukemia

Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W. Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P. Hunger, Carolyn A. Felix, Hao Wu, Patrick A. Brown, Erin M. Guest, David M. Barrett, Kathrin M. Bernt, Kai Tan
Journal: Blood
Blood (2022) 139 (14): 2198–2211.
https://doi.org/10.1182/blood.2021013442
Published: 2022
Includes: Supplemental data
Journal Articles

Gemtuzumab ozogamicin in infants with AML: results from the Children’s Oncology Group trials AAML03P1 and AAML0531

Clinical Trials & Observations
Erin M. Guest, Richard Aplenc, Lillian Sung, Susana C. Raimondi, Betsy A. Hirsch, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Jim Wang, Samir B. Kahwash, Amy Heerema-McKenney, Soheil Meshinchi, Alan S. Gamis
Journal: Blood
Blood (2017) 130 (7): 943–945.
https://doi.org/10.1182/blood-2017-01-762336
Published: 2017
Includes: Supplemental data
Journal Articles

Landscape of Somatic Mutations and Gene Expression Changes in Relapsed Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Rumen Kostadinov, PhD, Midhat Farooqi, MD PhD, Byunggil Yoo, MS, Emily Farrow, PhD CGC, Shannon Kelley, Margaret Gibson, Neil Miller, Erin M. Guest, MD, Patrick Brown, MD
Journal: Blood
Blood (2016) 128 (22): 1735.
https://doi.org/10.1182/blood.V128.22.1735.1735
Published: 2016
Journal Articles

Prognostic Significance of 11q23/ MLL Fusion Partners in Children with Acute Myeloid Leukemia (AML) - Results from the Children's Oncology Group (COG) Trial AAML0531

Erin M. Guest, MD, Betsy A. Hirsch, PhD, E. Anders Kolb, MD, Todd A. Alonzo, PhD, Robert Gerbing, BS, Richard Aplenc, MD PhD, Jessica Pollard, MD, Lillian Sung, MD PhD FRCPC, Soheil Meshinchi, MD PhD, Alan S. Gamis, MD MPH, Susana C. Raimondi, PhD
Journal: Blood
Blood (2016) 128 (22): 1211.
https://doi.org/10.1182/blood.V128.22.1211.1211
Published: 2016
Journal Articles

Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML

Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E Farrar, MD, Emilia L. Lim, PhD, Timothy Junius Triche, Jr., PhD, Katherine Tarlock, MD, Jaime Guidry Auvil, PhD, Betsy A. Hirsch, PhD, Susana C. Raimondi, PhD, Yussanne Ma, PhD, Marco A. Marra, PhD, Richard Aplenc, MD PhD, Erin M. Guest, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 774.
https://doi.org/10.1182/blood.V128.22.774.774
Published: 2016
Journal Articles

Treatment of 11q23/ MLL + AML with Gemtuzumab Ozogamicin: Results from the Randomized Phase III Children's Oncology Group Trial AAML0531

Jessica Pollard, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Lillian Sung, MD PhD, Richard Aplenc, MD PhD, Erin M. Guest, MD, Irwin D. Bernstein, MD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD, Alan S. Gamis, MD MPH
Journal: Blood
Blood (2015) 126 (23): 799.
https://doi.org/10.1182/blood.V126.23.799.799
Published: 2015
Journal Articles

Pneumocystis Jirovecii Pneumonia (PCP) in Children with Cancer: A Retrospective Cohort Analysis from the Pediatric Health Information System (PHIS) Database, 2004-2009

Erin M. Guest, MD, Matt Hall, PhD, Samir S. Shah, MD MSCE, Keith J. August, MD MSc, Joy M. Fulbright, MD, Jennifer L. Goldman, MD, Ram V. Kalpatthi, MD, Mohamed A. Radhi, MD, Alan S. Gamis, MD MPH
Journal: Blood
Blood (2014) 124 (21): 4836.
https://doi.org/10.1182/blood.V124.21.4836.4836
Published: 2014
Journal Articles

Gemtuzumab Ozogamicin (GO) in Infants with Acute Myeloid Leukemia (AML) – Combined Results from the Children’s Oncology Group (COG) Trials, AAML03P1 and AAML0531

Erin M. Guest, MD, Richard Aplenc, MD PhD, Lillian Sung, MD PhD, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Yi-Cheng Wang, MS, Samir B. Kahwash, MD, Amy Heerema-McKenney, MD, Soheil Meshinchi, MD PhD, Alan S. Gamis, MD MPH
Journal: Blood
Blood (2014) 124 (21): 377.
https://doi.org/10.1182/blood.V124.21.377.377
Published: 2014