Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 34

Sort by

Sort Order Select

Journal Articles

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A -rearranged leukemia

Blood (2022) 139 (14): 2198–2211.

https://doi.org/10.1182/blood.2021013442

Published: 2022

Includes: Supplemental data

Journal Articles

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Karen A. Urtishak, PhD, Wang Li-San, PhD, David T. Teachey, MD, Tasian K. Sarah, MD, Jeffrey S. Barrett, PhD, I-Ming L. Chen, Susan R. Atlas, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD

Blood (2013) 122 (21): 1669.

https://doi.org/10.1182/blood.V122.21.1669.1669

Published: 2013

Journal Articles

Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia

Blood (2013) 121 (14): 2689–2703.

https://doi.org/10.1182/blood-2012-04-425033

Published: 2013

Includes: Supplemental data

Journal Articles

Zebrafish Ortholog of Human DOT1L Regulates Primitive and Transient Definitive Hematopoiesis and Controls hoxa9 and meis1 Expression

Giulia Morello, BSc, Patrizia Porazzi, PhD, Enrico Moro, PhD, Francesco Argenton, PhD, Giuseppe Basso, MD, Carolyn A. Felix, MD, Giuseppe Germano, PhD

Blood (2012) 120 (21): 849.

https://doi.org/10.1182/blood.V120.21.849.849

Published: 2012

Journal Articles

Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study

Blood (2012) 119 (8): 1872–1881.

https://doi.org/10.1182/blood-2011-10-382861

Published: 2012

Includes: Supplemental data

Journal Articles

Predicting Clinical Dose-Exposure and Exposure-Response Relationships of Pan-Antiapoptotic BCL-2 Family Inhibitor Obatoclax in MLL Rearranged Infant Leukemias From Preclinical Disease Models and Adult Experience

Jeffrey S Barrett, PhD, Alena Y. Zhang, PhD, Karen A. Urtishak, PhD, Gwenn Danet-Desnoyers, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Carolyn A. Felix, MD

Blood (2011) 118 (21): 2580.

https://doi.org/10.1182/blood.V118.21.2580.2580

Published: 2011

Journal Articles

Unique Familial MLL -rearranged Precursor B Cell Infant Acute Lymphoblastic Leukemia (ALL) in Non-Twin Siblings

Karen A. Urtishak, PhD, Blaine W. Robinson, PhD, Jaclyn A. Biegel, PhD, Kim E. Nichols, MD, Julie W. Stern, MD, Carolyn A. Felix, MD

Blood (2011) 118 (21): 2417.

https://doi.org/10.1182/blood.V118.21.2417.2417

Published: 2011

Journal Articles

Mechanisms in Leukemia-Associated Chromosomal Translocations: Novel, High-Throughput Sequencing Method to Detect Topoisomerase II (TOP2) Cleavage Complexes Genome-Wide with Exact Base Resolution,

Carolyn A. Felix, MD, Marie L. Carillo, MS, Karen A. Urtishak, PhD, Isabelle C. Dragomir, BS, Michele E. Paessler, DO, Andrew D. Bantly, BS, Marybeth Helfrich, BS, Li-San Wang, PhD, Brian D. Gregory, PhD

Blood (2011) 118 (21): 3445.

https://doi.org/10.1182/blood.V118.21.3445.3445

Published: 2011

Journal Articles

Infant Acute Lymphoblastic Leukemias Are Pan-Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL - ENL , and gene Expression Profiles Determine Obatoclax IC 50 : A Report on the Children's Oncology Group (COG) P9407 Trial

Blood (2010) 116 (21): 2757.

https://doi.org/10.1182/blood.V116.21.2757.2757

Published: 2010

Journal Articles

af9 Regulates gata2 Expression During Early Hemangioblast Specification and Vascular Pattern Formation In Zebrafish.

Giuseppe Germano, PhD, Ilaria Guariento, BSc, Natascia Tiso, PhD, Blaine W. Robinson, PhD, Enrico Moro, PhD, Francesco Argenton, PhD, Carolyn A. Felix, MD, Giuseppe Basso, MD

Blood (2010) 116 (21): 2600.

https://doi.org/10.1182/blood.V116.21.2600.2600

Published: 2010

Journal Articles

Gene Expression Profiling Reveals Genes Predictive of Outcome In Infant Acute Lymphoblastic Leukemia (ALL) and Distinctive Age-Related Gene Expression Profiles (< 90 Days vs. > 90 Days): A Children's Oncology Group Study

Blood (2010) 116 (21): 412.

https://doi.org/10.1182/blood.V116.21.412.412

Published: 2010

Journal Articles

Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia

Ashley N. Mays, Neil Osheroff, Yuanyuan Xiao, Joseph L. Wiemels, Carolyn A. Felix, Jo Ann W. Byl, Kandeepan Saravanamuttu, Andrew Peniket, Robert Corser, Cherry Chang, Christine Hoyle, Anne N. Parker, Syed K. Hasan, Francesco Lo-Coco, Ellen Solomon, David Grimwade

Blood (2010) 115 (2): 326–330.

https://doi.org/10.1182/blood-2009-07-235051

Published: 2010

Includes: Supplemental data

Journal Articles

Zebrafish Mll Depletion Model Phenocopies Mammalian Mll Depletion and Implicates MLL as Master Regulator of Novel Developmental Hematopoietic Targets.

Blaine W. Robinson, PhD, Yuanquan Song, PhD, Giuseppe Germano, PhD, Patricia Ernst, PhD, Joshua Abrams, Marion Scott, Amy Kugath, Marybeth Helfrich, J. Oriol Sunyer, PhD, Jennifer Rhodes, PhD, Rita Balice-Gordon, PhD, Carolyn A. Felix, MD

Blood (2009) 114 (22): 3655.

https://doi.org/10.1182/blood.V114.22.3655.3655

Published: 2009

Journal Articles

Specific MLL Partner Genes in Infant Acute Lymphoblastic Leukemia (ALL) Associated with Outcome Are Linked to Age and White Blood Cell Count (WBC) at Diagnosis: A Report On the Children's Oncology Group (COG) P9407 Trial.

Blaine W. Robinson, PhD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Cheryl L. Willman, MD, Amanda R. Hudome, Elliot C. Woods, Nancy C. Ballantyne, Gregory H. Reaman, MD, Joanne M. Hilden, MD, Bruce M. Camitta, MD, Naomi J. Winick, MD, William L. Carroll, MD, Stephen P Hunger, MD, Zoann E. Dreyer, MD, Carolyn A. Felix, MD

Blood (2009) 114 (22): 907.

https://doi.org/10.1182/blood.V114.22.907.907

Published: 2009

Journal Articles

Age Is the Strongest Determinant of Leukemia Blast Cell Gene Expression in MLL -Rearranged Infant ALL and MLL-AF4 Directs a Distinct Gene Expression Profile Related to CNS Disease.

Blaine W. Robinson, PhD, Kajia Cao, PhD, Joanne M. Hilden, MD, Patricia A. Dinndorf, MD, Nyla A. Heerema, PhD, Harland N. Sather, Ron McGlennen, Stephen P. Hunger, MD, Gregory H. Reaman, MD, Li-San Wang, PhD, Carolyn A. Felix, MD

Blood (2008) 112 (11): 1200.

https://doi.org/10.1182/blood.V112.11.1200.1200

Published: 2008

Journal Articles

Pan-Anti-Apoptotic BCL-2 Family Inhibitor, Obatoclax, Activates Autophagic Cell Death Pathway and Has Potent Cytotoxicity in Infant and Pediatric MLL -Rearranged Leukemias

Alena Y. Zhang, PharmD, PhD, Blaine W. Robinson, PhD, Li-San Wang, PhD, Kajia Kao, PhD, Lori Cory, Jeffrey S. Barrett, PhD, Susan Atlas, PhD, I-Ming Chen, MS, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Jonni S. Moore, PhD, Craig B. Thompson, MD, Mondira Kundu, MD, PhD, Carolyn A. Felix, MD

Blood (2008) 112 (11): 2647.

https://doi.org/10.1182/blood.V112.11.2647.2647

Published: 2008

Journal Articles

Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants.

Alena Y. Zhang, PharmD, PhD, Blaine W. Robinson, PhD, Kajia Kao, PhD, Kathryn Behling, MD, PhD, Meenakshi Devidas, PhD, Todd Alonzo, PhD, Susana C. Raimondi, PhD, Andrew Carroll, PhD, Robert J. Arceci, MD, PhD, Alan Gamis, MD, Stephen P. Hunger, MD, Gregory H. Reaman, MD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Li-San Wang, PhD, Carolyn A. Felix, MD

Blood (2008) 112 (11): 2255.

https://doi.org/10.1182/blood.V112.11.2255.2255

Published: 2008

Journal Articles

Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis

Blood (2008) 112 (8): 3383–3390.

https://doi.org/10.1182/blood-2007-10-115600

Published: 2008

Journal Articles

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome

Blaine W. Robinson, Nai-Kong V. Cheung, Christos P. Kolaris, Suresh C. Jhanwar, John K. Choi, Neil Osheroff, Carolyn A. Felix

Blood (2008) 111 (7): 3802–3812.

https://doi.org/10.1182/blood-2007-07-096065

Published: 2008

Journal Articles

Cloning and Characterization of the Zebrafish mll Ortholog.

Blaine W. Robinson, PhD, Giuseppe Germano, PhD, Yuanquan Song, Rita J. Balice-Gordon, PhD, Carolyn A. Felix, MD

Blood (2007) 110 (11): 1249.

https://doi.org/10.1182/blood.V110.11.1249.1249

Published: 2007

NARROW

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A -rearranged leukemia

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia

Zebrafish Ortholog of Human DOT1L Regulates Primitive and Transient Definitive Hematopoiesis and Controls hoxa9 and meis1 Expression

Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study

Predicting Clinical Dose-Exposure and Exposure-Response Relationships of Pan-Antiapoptotic BCL-2 Family Inhibitor Obatoclax in MLL Rearranged Infant Leukemias From Preclinical Disease Models and Adult Experience

Unique Familial MLL -rearranged Precursor B Cell Infant Acute Lymphoblastic Leukemia (ALL) in Non-Twin Siblings

Mechanisms in Leukemia-Associated Chromosomal Translocations: Novel, High-Throughput Sequencing Method to Detect Topoisomerase II (TOP2) Cleavage Complexes Genome-Wide with Exact Base Resolution,

Infant Acute Lymphoblastic Leukemias Are Pan-Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL - ENL , and gene Expression Profiles Determine Obatoclax IC 50 : A Report on the Children's Oncology Group (COG) P9407 Trial

af9 Regulates gata2 Expression During Early Hemangioblast Specification and Vascular Pattern Formation In Zebrafish.

Gene Expression Profiling Reveals Genes Predictive of Outcome In Infant Acute Lymphoblastic Leukemia (ALL) and Distinctive Age-Related Gene Expression Profiles (< 90 Days vs. > 90 Days): A Children's Oncology Group Study

Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia

Zebrafish Mll Depletion Model Phenocopies Mammalian Mll Depletion and Implicates MLL as Master Regulator of Novel Developmental Hematopoietic Targets.

Specific MLL Partner Genes in Infant Acute Lymphoblastic Leukemia (ALL) Associated with Outcome Are Linked to Age and White Blood Cell Count (WBC) at Diagnosis: A Report On the Children's Oncology Group (COG) P9407 Trial.

Age Is the Strongest Determinant of Leukemia Blast Cell Gene Expression in MLL -Rearranged Infant ALL and MLL-AF4 Directs a Distinct Gene Expression Profile Related to CNS Disease.

Pan-Anti-Apoptotic BCL-2 Family Inhibitor, Obatoclax, Activates Autophagic Cell Death Pathway and Has Potent Cytotoxicity in Infant and Pediatric MLL -Rearranged Leukemias

Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants.

Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome

Cloning and Characterization of the Zebrafish mll Ortholog.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only