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Journal Articles

Discovery of the Unique GMP-Grade iPSC Clones That Give Rise to Functional, High Purity, Matured CD8 Alpha Beta T or Gamma Delta T with Exponential Expansion Capacity

Ying-Tsen Tung, Chih-Lung Chen, Annie Yi-Ting Lai, Chien-Yu Hsu, Chien-Hsi Chen, Po-Fan Chu, Lin-Yu Liao, Tzu-Chien Kuo, Chieh-Teng Cheng, Chun-Yu Lin, Wan-Chen Tsai, Wei-Ting Chen, Darien Zhing Herr Chan, Hsin-Hua Cho, Cheng-Kai Wang, Yo-Chuen Lin, Jin-Yi Lu, Lee-Yieng Lim, Jhang-Sian Yu, Ming-Chin Ko, Chia-Hung Lin, Yi-Han Dai, I-Ting Chen, Fang-Pei Chang, Shao-Ju Weng, Ting-Yi Wu, Yuan-Yu Hsia, Fu-Fei Hsu, Lillian Yi-Ting Lai, Shiou-Ling Jian, Shih-Wen Huang, Yu-Chih Peng, Ke-Hsun Hsu, Liang-Yi Chen, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Yi-Hung Ou, Min-Ren Chiang, Wen-Hao Wang, Tsung-Hao Yeh, Xiaming Peng, Yang Shi, Pei Zhang, Ya-Chu Yu, Yun Gao, Yen-Hsien Lee, Pei-Chun Wu, Ta-Hsun Liao, De-Kuan Chang, Lien-Szu Wu, Jen-Chih Chi, Ching-Ying Huang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7195.
https://doi.org/10.1182/blood-2024-203106
Published: 2024
Journal Articles

Investigating Prognostic Value of Immunoglobulin Next-Generation Sequencing in B Cell Non-Hodgkin Lymphoma Patients Undergoing Chimeric Antigen Receptor T-Cell Therapy

Yi-Lun Zhang, Lingshuang Sheng, Rong Shen, Wen Wu, Xin Zheng, Li Wang, Shu Cheng, Peng-Peng Xu, Qi-Jie Jian, Bo Peng, Ke Zhang, Fei Pang, Kai Wang, Zi-Xun Yan, Wei-Li Zhao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6208.
https://doi.org/10.1182/blood-2024-209889
Published: 2024
Journal Articles

The Efficacy of Venetoclax + LDAC and CPX-351 over Traditional Regimen in Older Patients with AML Not Eligible for Intensive Therapy: A Meta-Analysis and Systematic Review

Kai Wang, Ngowari Pokima, Praneeth Reddy Keesari, Khalil El-gharib, Michael Widjaja, Suzanne El-Sayegh
Journal: Blood
Blood (2024) 144 (Supplement 1): 6073.
https://doi.org/10.1182/blood-2024-208801
Published: 2024
Journal Articles

Safety and Feasibility of Intrathecal Infusion of CD19 and/or CD22 CAR T Cells in r/r B-ALL Patients with CNSL or High-Risk CNS Relapse

Yibing Zhang, Jing PAN, Fan Wu, Zhuojun Ling, Kai Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3466.
https://doi.org/10.1182/blood-2024-201376
Published: 2024
Journal Articles

NOTCH1 gene Fusions Occur Frequently in Refractory or Relapsed (R/R) T-Cell Lymphomablastic Lymphoma

Yu Xia, Kai Wang, Keyan Yang, Ling Jin, Ying Liu, Yueping Jia, Yunpeng Dai, Lihua Yang, Rong Liu, Lian Jiang, Zhongjin Xu, Ansheng Liu, Xiaojun Yuan, Jian Wang, Yonghong Zhang, Qinlong Zheng
Journal: Blood
Blood (2024) 144 (Supplement 1): 4225.
https://doi.org/10.1182/blood-2024-212203
Published: 2024
Journal Articles

CD7 CAR T-Cell Therapy in Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia: A Retrospective Study

Jing PAN, Liping Zhao, Fan Wu, Zhuojun Ling, Kai Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 964.
https://doi.org/10.1182/blood-2024-201362
Published: 2024
Journal Articles

Multi-Omics Integration to Elucidate the Cis-Regulatory Network Re-Wiring upon NSD2 Degradation in t(4;14) Multiple Myeloma

Bo Hu, Hardik Modi, Diana Jankeel, Jacob T. Edwards, Junfei Zhao, Chad C. Bjorklund, Gaurav Jain, Patrick R. Hagner, Maria Ortiz, Zhongying Mo, Celia Fontanillo, Christoph W. Zapf, Antonia Lopez-Girona, Neil Bence, Kai Wang, Anita K. Gandhi, Mark Rolfe, Deborah S. Mortensen, Lynda Groocock
Journal: Blood
Blood (2024) 144 (Supplement 1): 1881.
https://doi.org/10.1182/blood-2024-203621
Published: 2024
Journal Articles

iPSC-Derived CAR-Gamma Delta T with Novel Combinatorial KO Demonstrated Extended Longevity and Profound Anti-Tumor Efficacy without Cytokine Support in Preclinical Studies

Jhang-Sian Yu, Chia-Hung Lin, Ying-Tsen Tung, Fang-Pei Chang, Edward Po-Fan Chu, Shiou-Ling Jian, Fu-Fei Hsu, Ming-Chin Ko, Yi-Han Dai, Chieh-Teng Cheng, Tzu-Chien Kuo, I-Ting Chen, Ting-Yi Wu, Jin-Yi Lu, Ke-Hsun Hsu, Wei-Ting Chen, Darien Zhing Herr Chan, Yi-Ting Lai, Shao-Ju Weng, Liang-Yi Chen, Yuan-Yu Hsia, Yi-Hung Ou, Yo-Chuen Lin, Shih-Wen Huang, Yu-Chih Peng, Chien-Hsi Chen, Chien-Yu Hsu, Yi-Ting Lai, Chih-Lung Chen, Chun-Yu Lin, Lin-Yu Liao, Wan-Chen Tsai, Hsin-Hua Cho, Cheng-Kai Wang, Lee-Yieng Lim, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Wen-Hao Wang, Tsung-Hao Yeh, Min-Ren Chiang, Ruyue Ji, Jen-Chih Chi, Lien-Szu Wu, Jennifer Huang, De-Kuan Chang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4790.
https://doi.org/10.1182/blood-2024-205086
Published: 2024
Journal Articles

From Harmless to Harmful: Meta-Analysis and Systematic Review of Adverse Clinical Outcomes in Sickle Cell Trait

Ngowari Pokima, Khalil El-gharib, Zaid Khamis, Melissa Marseille, Praneeth Reddy Keesari, Mary Owolabi, Kai Wang, Marcel Odaimi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3903.
https://doi.org/10.1182/blood-2024-205987
Published: 2024
Journal Articles

CAR T-Cell Therapy in Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia/Lymphoma: A Retrospective Study

Liping Zhao, Qi Zhou, Chen Chen, Zhuojun Ling, Kai Wang, Fan Wu, Jinlong Xu, Jiajia Duan, Zelin Wang, Quangang Wang, Jing PAN
Journal: Blood
Blood (2023) 142 (Supplement 1): 3480.
https://doi.org/10.1182/blood-2023-182538
Published: 2023
Journal Articles

Combination of Thrombopoietin Receptor Agonist and Recombinant Human Thrombopoietin for Treating Cancer Therapy Induced Thrombopenia

Dong Yan, Jing Yang, Yunfei Gao, Peihua Zhang, Chan Zhang, Yurong Cheng, Xuyang Zhang, Cong Fan, Kai Wang, Siyu Zhu, Baogen Zhang, Fengyuan Liu, Yingying Tong, Lei Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 8420–8421.
https://doi.org/10.1182/blood-2022-164490
Published: 2022
Journal Articles

Elucidating the Molecular Mechanisms of Action of CC-99282, a Novel Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Agent, Via Genome-Wide CRISPR Screen in a Preclinical Model of Non-Hodgkin Lymphoma (NHL)

Zhongying Mo, Lynda Groocock, Scott Wood, Diana Jankeel, Preethi Janardhanan, Derek Mendy, Michael Angelo, In Sock Jang, Celia Fontanillo, Kai Wang, Mark Rolfe, Antonia Lopez-Girona
Journal: Blood
Blood (2022) 140 (Supplement 1): 8860–8861.
https://doi.org/10.1182/blood-2022-159393
Published: 2022
Journal Articles

Efficacy and Safety of Donor-Derived CD7 CAR T Cells for r/r T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Interim Analysis from a Phase 2 Trial

Yue Tan, Jing Pan, Biping Deng, Zhuojun Ling, Song Weiliang, Zhenglong Tian, Ming Cao, Jinlong Xu, Jiajia Duan, Zelin Wang, Kai Wang, Chunyu Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 4602–4603.
https://doi.org/10.1182/blood-2022-165819
Published: 2022
Journal Articles

CAR-T Therapy for a Child with Refractory Inflammatory Myofibroblastic Tumor

Kai Wang, Yan Liu, Lung-Ji Chang, Huyong Zheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10355–10356.
https://doi.org/10.1182/blood-2022-165248
Published: 2022
Journal Articles

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A -rearranged leukemia

Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W. Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P. Hunger, Carolyn A. Felix, Hao Wu, Patrick A. Brown, Erin M. Guest, David M. Barrett, Kathrin M. Bernt, Kai Tan
Journal: Blood
Blood (2022) 139 (14): 2198–2211.
https://doi.org/10.1182/blood.2021013442
Published: 2022
Includes: Supplemental data
Journal Articles

Single-Cell Multiomics Reveals Increased Plasticity, Resistant Populations and Stem-Cell-like Blasts in KMT2A-Rearranged Leukemia

Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P Hunger, Hao Wu, Patrick A. Brown, Erin Guest, David M Barrett, Kathrin M. Bernt, Kai Tan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2203.
https://doi.org/10.1182/blood-2021-146102
Published: 2021
Journal Articles

Validation of Next Generation Sequencing-Based Clonality Assays for Diagnosis and Minimal Residual Disease Tracking in Lymphoid Malignancies

Haiyan Wu, Feng Li, Jiacheng Cai, Ke Zhang, Xin Zheng, Jicheng Yao, Weifeng Wang, Kai Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2959.
https://doi.org/10.1182/blood-2021-150151
Published: 2021
Journal Articles

Comparative Analysis of Clinicopathological Features and Genetic Landscape of Relapsed/ Refractory and Effectively Treated Extranodal Nasal NK/ T Cell Lymphoma

Limin Gao, Huifang Li, Qi-Jie Jian, Wenyan Zhang, Sha Zhao, Kai Wang, Weiping Liu
Journal: Blood
Blood (2021) 138 (Supplement 1): 1384.
https://doi.org/10.1182/blood-2021-149335
Published: 2021
Journal Articles

RNF217 regulates iron homeostasis through its E3 ubiquitin ligase activity by modulating ferroportin degradation

Li Jiang, Jiaming Wang, Kai Wang, Hao Wang, Qian Wu, Cong Yang, Yingying Yu, Pu Ni, Yueyang Zhong, Zijun Song, Enjun Xie, Ronggui Hu, Junxia Min, Fudi Wang
Journal: Blood
Blood (2021) 138 (8): 689–705.
https://doi.org/10.1182/blood.2020008986
Published: 2021
Includes: Supplemental data
Journal Articles

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells

Christine Surka, Liqing Jin, Nathan Mbong, Chin-Chun Lu, In Sock Jang, Emily Rychak, Derek Mendy, Thomas Clayton, Elizabeth Tindall, Christy Hsu, Celia Fontanillo, Eileen Tran, Adrian Contreras, Stanley W. K. Ng, Mary Matyskiela, Kai Wang, Philip Chamberlain, Brian Cathers, James Carmichael, Joshua Hansen, Jean C. Y. Wang, Mark D. Minden, Jinhong Fan, Daniel W. Pierce, Michael Pourdehnad, Mark Rolfe, Antonia Lopez-Girona, John E. Dick, Gang Lu
Journal: Blood
Blood (2021) 137 (5): 661–677.
https://doi.org/10.1182/blood.2020008676
Published: 2021
Includes: Supplemental data