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Neil Bence
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Journal Articles

Development of a ZBTB7A and Wiz Dual Degrading, HbF-Activating CELMoD™ for the Treatment of Sickle Cell Disease

Emily Rychak, Goldie Yuan Lam Lui, Cristhian Fimbres, Christine Kim Kang, Younguk Sun, Sophie Peng, Jingjing Deng, Sarah Franc, Eugene Ciccimaro, Kimberly Peacock, Minerva Tran, Andy Christoforou, Jinyi Zhu, Geraldine Polido, Barbra Pagarigan, Scott Johnson, Faye Wang, Paula Katavolos, Bonny Gaffney, Estela Garcia, France Landry, Fletcher Paddison, Petia Shipkova, Hannah Powers, Giorgio Tamò, August Dietrich, Soraya Carrancio, Radha Ramakrishnan, Karen Augustine, Rama Krishna Narla, Thomas Cummins, Mark Rolfe, Neil Bence, Antonia Lopez-Girona
Journal: Blood
Blood (2024) 144 (Supplement 1): 169.
https://doi.org/10.1182/blood-2024-203653
Published: 2024
Journal Articles

BMS-986458 a Potential First-in-Class, Highly Selective, Potent and Well Tolerated BCL6 Ligand Directed Degrader (LDD) Demonstrates Multi-Modal Anti-Tumor Efficacy for the Treatment of B-Cell Non-Hodgkin's Lymphoma

Lynda Groocock, Gauri Deb, Jinyi Zhu, Jim Gamez, Paola Castiglioni, Manuel Sanchez-Castillo, Justin Schumacher, Alicia Benitez Rondan, Diana Jankeel, Karla Martinez-Garcia, Scott Wood, Andy Christoforou, Carla Guarinos, Wei Zhang, Rama Krishna Narla, Christoph W. Zapf, Soraya Carrancio, Daniel W. Pierce, Mark Rolfe, Neil Bence, Antonia Lopez-Girona, Deborah S. Mortensen
Journal: Blood
Blood (2024) 144 (Supplement 1): 957.
https://doi.org/10.1182/blood-2024-210951
Published: 2024
Journal Articles

Multi-Omics Integration to Elucidate the Cis-Regulatory Network Re-Wiring upon NSD2 Degradation in t(4;14) Multiple Myeloma

Bo Hu, Hardik Modi, Diana Jankeel, Jacob T. Edwards, Junfei Zhao, Chad C. Bjorklund, Gaurav Jain, Patrick R. Hagner, Maria Ortiz, Zhongying Mo, Celia Fontanillo, Christoph W. Zapf, Antonia Lopez-Girona, Neil Bence, Kai Wang, Anita K. Gandhi, Mark Rolfe, Deborah S. Mortensen, Lynda Groocock
Journal: Blood
Blood (2024) 144 (Supplement 1): 1881.
https://doi.org/10.1182/blood-2024-203621
Published: 2024
Journal Articles

Highly Potent BTK Degradation Induced By NRX0492 As a Therapeutic Strategy for CLL

Deyi Zhang, PhD, Hailey Harris, Aileen Kelly, PhD, Daniel W Robbins, May Tan, Timothy Ingallinera, Neil Bence, Arthur T Sands, Sivasubramanian Baskar, Sarah E. M. Herman, Adrian Wiestner, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 174.
https://doi.org/10.1182/blood-2019-126921
Published: 2019
Journal Articles

Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies

Aileen Kelly, PhD, Daniel W Robbins, May Tan, Austin Tenn-McClellan, Joel McIntosh, Jeffrey Wu, Zef Konst, Daisuke Kato, Luz Perez, Jennifer Tung, Anna Kolobova, Timothy Ingallinera, Jenny McKinnell, Dahlia Weiss, Mark Noviski, Jordan Ye, Ge Peng, Mario Cardozo, Jeff Mihalic, Steve Basham, Ryan Rountree, Dane E Karr, Neil Bence, Christoph W Zapf, Arthur T Sands
Journal: Blood
Blood (2019) 134 (Supplement_1): 3805.
https://doi.org/10.1182/blood-2019-129262
Published: 2019
Journal Articles

Treatment Emergent Mutations in NAEβ Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Pre-Clinical AML and DLBCL Models

Michael Milhollen, Michael Thomas, Tary Traore, Usha Narayanan, Jessica Riceberg, Todd Sells, PhD, Ben Amidon, PhD, Mark Manfredi, PhD, Neil Bence, PhD, James Brownell, PhD, Larry Dick, PhD, Erik Koenig, James Gavin, Peter G Smith, PhD
Journal: Blood
Blood (2011) 118 (21): 1413.
https://doi.org/10.1182/blood.V118.21.1413.1413
Published: 2011