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Carla Guarinos
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Journal Articles

BMS-986458 a Potential First-in-Class, Highly Selective, Potent and Well Tolerated BCL6 Ligand Directed Degrader (LDD) Demonstrates Multi-Modal Anti-Tumor Efficacy for the Treatment of B-Cell Non-Hodgkin's Lymphoma

Lynda Groocock, Gauri Deb, Jinyi Zhu, Jim Gamez, Paola Castiglioni, Manuel Sanchez-Castillo, Justin Schumacher, Alicia Benitez Rondan, Diana Jankeel, Karla Martinez-Garcia, Scott Wood, Andy Christoforou, Carla Guarinos, Wei Zhang, Rama Krishna Narla, Christoph W. Zapf, Soraya Carrancio, Daniel W. Pierce, Mark Rolfe, Neil Bence, Antonia Lopez-Girona, Deborah S. Mortensen
Journal: Blood
Blood (2024) 144 (Supplement 1): 957.
https://doi.org/10.1182/blood-2024-210951
Published: 2024
Journal Articles

Golcadomide (GOLCA) ± Rituximab (RTX) Demonstrates Durable Efficacy and Is Well Tolerated in Patients (pts) with Relapsed/Refractory Follicular Lymphoma (R/R FL): Updated Results from the Phase 1/2 CC-99282-NHL-001 Study

Julio C. Chavez, Guilherme Fleury Perini, Loretta Nastoupil, Judit Mészáros Joergensen, Pierre Bories, Bijou Fontanet, Pier Luigi Zinzani, Javier Munoz, Daniel Morillo Giles, Cecilia Carpio, Abel Costa, Won Seog Kim, Parth Rao, Bérengère de Moucheron, Yang Gang, Carla Guarinos, Akshay Sudhindra, Michael Pourdehnad, Jean-Marie Michot
Journal: Blood
Blood (2024) 144 (Supplement 1): 3018.
https://doi.org/10.1182/blood-2024-203131
Published: 2024
Journal Articles

Cell-Intrinsic and Immune-Mediated Effects in Lymphoma Patients Treated with Golcadomide and Associations with Treatment Outcome

Soraya Carrancio, Jessica Voetsch, Alberto Risueño, Carla Guarinos, Siddhesh Kulkarni, Mandeep Takhar, Matthew E. Stokes, Bérengère de Moucheron, Laura Furman, Julio C. Chavez, Jean-Marie Michot, Loretta Nastoupil, Daniel W. Pierce, Danielle Greenawalt, Michael Pourdehnad
Journal: Blood
Blood (2024) 144 (Supplement 1): 3104.
https://doi.org/10.1182/blood-2024-203139
Published: 2024
Journal Articles

Association of Immune Dynamics and Treatment Outcome in Patients (pts) with Relapsed/Refractory Non-Hodgkin Lymphoma (R/R NHL) Treated with the Novel Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Agent CC-99282

Soraya Carrancio, Wen-Chi Chou, Alberto Risueño, Carla Guarinos, Gonzalo Lopez, Jean-Marie Michot, Loretta J. Nastoupil, Julio Chavez, Cecilia Carpio, Silvia Ferrari, Tatyana A. Feldman, Daniel Morillo Giles, Antonio Pinto, Danielle Greenawalt, Daniel W. Pierce, Michael Pourdehnad
Journal: Blood
Blood (2022) 140 (Supplement 1): 6455–6457.
https://doi.org/10.1182/blood-2022-159585
Published: 2022
Journal Articles

Clinical Activity of CC-99282, a Novel, Oral Small Molecule Cereblon E3 Ligase Modulator (CELMoD) Agent, in Patients (Pts) with Relapsed or Refractory Non-Hodgkin Lymphoma (R/R NHL) - First Results from a Phase 1, Open-Label Study

Jean-Marie Michot, Julio C. Chavez, Cecilia Carpio, Silvia Ferrari, Tatyana A. Feldman, Daniel Morillo, John Kuruvilla, Antonio Pinto, Vincent Ribrag, Emmanuel Bachy, Tonia J Buchholz, Soraya Carrancio, Carla Guarinos, Fan Wu, Shaoyi Li, Poliana Patah, Michael Pourdehnad, Loretta Nastoupil
Journal: Blood
Blood (2021) 138 (Supplement 1): 3574.
https://doi.org/10.1182/blood-2021-147333
Published: 2021
Journal Articles

Synergistic Combination Activity of the Novel GSPT1 Degrader CC-90009 in Acute Myeloid Leukemia Models

Daniel W. Pierce, Tsun-Wen Sheena Yao, Emily Pace, Hongbin Wang, Pierre Flandin-Blety, Alicia Benitez, Carla Guarinos, Matthew Hoffmann, Soraya Carrancio, Jinhong Fan, Michael Pourdehnad
Journal: Blood
Blood (2021) 138 (Supplement 1): 3330.
https://doi.org/10.1182/blood-2021-147160
Published: 2021
Journal Articles

CC-99282 is a Novel Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Agent with Enhanced Tumoricidal Activity in Preclinical Models of Lymphoma

Soraya Carrancio, Lynda Groocock, Preethi Janardhanan, Diana Jankeel, Ryan Galasso, Carla Guarinos, Rama K. Narla, Matthew Groza, Jim Leisten, Daniel W. Pierce, Mark Rolfe, Antonia Lopez-Girona
Journal: Blood
Blood (2021) 138 (Supplement 1): 1200.
https://doi.org/10.1182/blood-2021-148068
Published: 2021