1-20 of 41
Maria Ortiz
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Golcadomide-Mediated Degradation of Aiolos/Ikaros Synergizes with BET Inhibitors through Bidirectional Restructuring of the Directly Regulated Epigenetic Environment in DLBCL

Chih-Chao Hsu, Junfei Zhao, Ann Polonskaia, Chad C. Bjorklund, Maria Ortiz Estevez, Anita K. Gandhi, Patrick R. Hagner
Journal: Blood
Blood (2024) 144 (Supplement 1): 2739.
https://doi.org/10.1182/blood-2024-200270
Published: 2024
Journal Articles

A Single Cell Atlas of Follicular Lymphoma across Clinical Stages Defines Tumor B Cell Archetypes, Immune Microenvironment Heterogeneity and Novel Cell States Associated with High-Risk FL

Alexandre Sarrabay, Sabrina Baaklini, Camille Barthelemy, Laurine Gil, Alicia Beyou, Laila Dahbi, Noushin Mossadegh-Keller, Caroline Huber, Jean-Marc Navarro, Gilles Salles, Gabriel Brisou, Maria Ortiz Estevez, Matthew E. Stokes, Sahil Seth, C. Chris Huang, Mark Kaplan, Lionel Spinelli, Anita K. Gandhi, Bertrand Nadel, Pierre Milpied, Sandrine Roulland
Journal: Blood
Blood (2024) 144 (Supplement 1): 740.
https://doi.org/10.1182/blood-2024-209642
Published: 2024
Journal Articles

Subtype-Specific Mechanisms of Treatment Resistance and Relapse in Diffuse Large B Cell Lymphoma (DLBCL)

Janek S. Walker, Kerstin Wenzl, Joseph P. Novak, Matthew E. Stokes, Melissa A. Hopper, Abigail R. Dropik, Miranda S. Laverty, Allison M. Bock, Vivekananda Sarangi, Maria Ortiz, Nicholas Stong, Chris Huang, Matthew J. Maurer, Brian K. Link, Stephen M. Ansell, Thomas M. Habermann, Thomas E. Witzig, Rebecca L. King, Grzegorz S. Nowakowski, James R. Cerhan, Anita K. Gandhi, Anne J. Novak
Journal: Blood
Blood (2024) 144 (Supplement 1): 2977.
https://doi.org/10.1182/blood-2024-208182
Published: 2024
Journal Articles

Genomic and Single Cell Investigation of MRD Clonality in Genetically Engineered Mouse Models of Multiple Myeloma

Junfei Zhao, Marta Larrayoz, Chad C. Bjorklund, Anita K. Gandhi, Jose A. Martinez-Climent, Patrick R. Hagner, Maria Ortiz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1409.
https://doi.org/10.1182/blood-2024-210958
Published: 2024
Journal Articles

Multi-Omics Integration to Elucidate the Cis-Regulatory Network Re-Wiring upon NSD2 Degradation in t(4;14) Multiple Myeloma

Bo Hu, Hardik Modi, Diana Jankeel, Jacob T. Edwards, Junfei Zhao, Chad C. Bjorklund, Gaurav Jain, Patrick R. Hagner, Maria Ortiz, Zhongying Mo, Celia Fontanillo, Christoph W. Zapf, Antonia Lopez-Girona, Neil Bence, Kai Wang, Anita K. Gandhi, Mark Rolfe, Deborah S. Mortensen, Lynda Groocock
Journal: Blood
Blood (2024) 144 (Supplement 1): 1881.
https://doi.org/10.1182/blood-2024-203621
Published: 2024
Journal Articles

Single-Cell Atlas of Diffuse Large B-Cell Lymphoma Reveals Integrated Malignant B Cell and Tumor Microenvironment Characteristics Associated with Clinical Response

Sabrina Baaklini, Alexandre Sarrabay, Adrien Mazuel, Bertrand Escaliere, Chuang Dong, Camille Barthelemy, Laurine Gil, Laila Dahbi, Noushin Mossadegh-Keller, Nathalie Van Acker, Pauline Gravelle, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, François Lemonnier, Gilles Salles, Corinne Haioun, Gabriel Brisou, Matthew E. Stokes, Sahil Seth, Maria Ortiz Estevez, Camille Laurent, Lionel Spinelli, Mark Kaplan, C. Chris Huang, Anita K. Gandhi, Bertrand Nadel, Sandrine Roulland, Pierre Milpied
Journal: Blood
Blood (2024) 144 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2024-209815
Published: 2024
Journal Articles

DNMT3A-Mutant Clonal Haematopoiesis Is Associated with Worse Recovery after ST-Elevation Myocardial Infarction Via Increased Inflammation

Sarah J Mackie, Matthew Sadler, Maroof Hasan, Lynette Graver, Rupavidhya Mondi Anandhakrishna, Fulye Argunhan, Louis-Francois Handfield, Hosanna Assefa-Kebede, Laarni Bogaanay, Prodromos Chatzikyriakou, Pilar Casares Alaez, Antonio Cannata, Mohammad Al-Agil, Amandine Tan, Maria Ortiz Estevez, Ching-Pin Chang, Rajasekhar N.V.S. Suragani, Anita K. Gandhi, Ajay Shah, Theresa McDonagh, Aleksander Ivetic, Ghulam Mufti, Giorgio Napolitani, Daniel Bromage, Lynn Quek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2024-203813
Published: 2024
Journal Articles

Differential Chromatin Organization between t(4;14) and Non-t(4;14) Multiple Myeloma Driven By the Histone Methyltransferase NSD2

Chad C. Bjorklund, Junfei Zhao, Gaurav Jain, Natasha Shtraizent, Maria Ortiz, Sambuddo Mukherjee, Patrick R Hagner, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3295.
https://doi.org/10.1182/blood-2023-190137
Published: 2023
Journal Articles

A Single Cell Atlas of Diffuse Large B Cell Lymphomas Reveals Distinct Cellular States Predictive of Outcomes

Sabrina Baaklini, Alexandre Sarrabay, Camille Barthelemy, Laila Dahbi, Laurine Gil, Noushin Mossadegh-Keller, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Bertrand Escaliere, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, Francois Lemonnier, Gabriel Brisou, Corinne Haioun, Pauline Gravelle, Camille Laurent, Lionel Spinelli, C Chris Huang, Matthew E Stokes, Sahil Seth, Maria Ortiz, Anita K. Gandhi, Bertrand Nadel, Pierre Milpied, Sandrine Roulland
Journal: Blood
Blood (2023) 142 (Supplement 1): 848.
https://doi.org/10.1182/blood-2023-173929
Published: 2023
Journal Articles

Mezigdomide Reverses T-Cell Exhaustion through Degradation of Aiolos/Ikaros and Reinvigoration of Cytokine Production Pathways

Hsiling Chiu, Junfei Zhao, Maria Ortiz Estevez, Patrick R Hagner, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 335.
https://doi.org/10.1182/blood-2023-189445
Published: 2023
Journal Articles

Molecular Classification of Relapsed DLBCL Reveals Novel Biologic Subgroups

Kerstin Wenzl, Matthew E Stokes, Joseph P. Novak, Allison M. Bock, Melissa A. Hopper, Jordan Krull, Abigail R. Dropik, Janek S. Walker, Miranda S. Laverty, Vivekananda Sarangi, Raphael Mwangi, Maria Ortiz, Nicholas Stong, C. Chris Huang, Matthew J. Maurer, Lisa M. Rimsza, Brian K. Link, Rebecca King, Stephen M Ansell, Thomas M. Habermann, Thomas E. Witzig, Grzegorz S. Nowakowski, James R. Cerhan, Anita K. Gandhi, Anne J. Novak
Journal: Blood
Blood (2023) 142 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2023-180949
Published: 2023
Journal Articles

RRMM and Post-BCMA Treated Subjects from the CC-220-MM-001 Study Show Increased Genomic Aberrations Associated with High-Risk and Significant Dysfunction in CD4+ T-Cell Compartment Compared to NDMM Subjects

Michael Amatangelo, Erin Flynt, Nicholas Stong, Maria Ortiz, Pradipta Ray, Maria Wang, Niels W.C.J. van de Donk, Sagar Lonial, Aparna Raval, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4665.
https://doi.org/10.1182/blood-2023-178912
Published: 2023
Journal Articles

The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM

Clinical Trials & Observations
Nicholas Stong, María Ortiz-Estévez, Fadi Towfic, Mehmet Samur, Amit Agarwal, Jill Corre, Erin Flynt, Nikhil Munshi, Hervé Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (13): 1574–1583.
https://doi.org/10.1182/blood.2022016212
Published: 2023
Includes: Supplemental data
Journal Articles

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

Naser Ansari-Pour, Mehmet Samur, Erin Flynt, Sarah Gooding, Fadi Towfic, Nicholas Stong, Maria Ortiz Estevez, Konstantinos Mavrommatis, Brian Walker, Gareth Morgan, Nikhil Munshi, Herve Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (6): 620–633.
https://doi.org/10.1182/blood.2022017010
Published: 2023
Includes: Supplemental data
Journal Articles

Integrative Genomics Identifies a High-Risk Metabolic and TME Depleted Signature That Predicts Early Clinical Failure in DLBCL

Kerstin Wenzl, Matthew E Stokes, Joseph P. Novak, Sana Khan, Melissa A. Hopper, Jordan E. Krull, Abigail Dropik, Vivekananda Sarangi, Raphael Mwangi, Maria Ortiz, Nicholas Stong, C. Chris Huang, Matthew J. Maurer, Lisa M. Rimsza, Brian K. Link, Susan L. Slager, Yan Asmann, Patrizia Mondello, Ryan D. Morin, Stephen M. Ansell, Thomas M. Habermann, Andrew L. Feldman, Rebecca L. King, Grzegorz S. Nowakowski, James R. Cerhan, Anita K. Gandhi, Anne J. Novak
Journal: Blood
Blood (2022) 140 (Supplement 1): 1742–1744.
https://doi.org/10.1182/blood-2022-159620
Published: 2022
Journal Articles

Biological Features of a High-Risk Transcriptional Molecular Subtype in Diffuse Large B-Cell Lymphoma

Matthew E Stokes, Kerstin Wenzl, C. Chris Huang, Maria Ortiz Estevez, Matthew J. Maurer, Nicholas Stong, Patrick Hagner, Yumi Nakayama, Chih-Chao Hsu, Samuel A Danziger, Fadi Towfic, Rebecca L. King, Joel S. Parker, Brian K. Link, Susan L. Slager, Vivekananda Sarangi, Yan Asmann, Joseph P. Novak, Akshay Sudhindra, Stephen M. Ansell, Thomas M. Habermann, Grzegorz S. Nowakowski, James R. Cerhan, Anne J. Novak, Anita K. Gandhi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3548–3550.
https://doi.org/10.1182/blood-2022-170228
Published: 2022
Journal Articles

Molecular Landscape of Primary Refractory DLBCL

Allison M. Bock, Kerstin Wenzl, Matthew E. Stokes, Joseph P. Novak, Melissa A. Hopper, Jordan E. Krull, Abigail Dropik, Vivekananda Sarangi, Maria Ortiz, Nicholas Stong, C. Chris Huang, Matthew J. Maurer, Rebecca L. King, Richard Curtis Godby, Umar Farooq, Yucai Wang, Stephen M. Ansell, Thomas M. Habermann, James R. Cerhan, Anita K. Gandhi, Grzegorz (Greg) Nowakowski, Anne J. Novak
Journal: Blood
Blood (2022) 140 (Supplement 1): 9221–9223.
https://doi.org/10.1182/blood-2022-156497
Published: 2022
Journal Articles

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma

Brief Report
Sarah Gooding, Naser Ansari-Pour, Mohammad Kazeroun, Kubra Karagoz, Ann Polonskaia, Mirian Salazar, Evie Fitzsimons, Korsuk Sirinukunwattana, Selina Chavda, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William Pierceall, Daniel Royston, Kwee Yong, Karthik Ramasamy, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2022) 140 (16): 1816–1821.
https://doi.org/10.1182/blood.2022015909
Published: 2022
Includes: Supplemental data
Journal Articles

Super-Enhancer Driven Regulation of CKS1B in Multiple Myeloma: Implications in Mediating Response to BET Inhibitor and Celmod Agent Combination

Aarif Ahsan, Ann Polonskaia, Chih-Chao Hsu, Chad C Bjorklund, Maria Ortiz Estevez, Fadi Towfic, Nizar J. Bahlis, Michael Pourdehnad, Erin Flynt, Aarif Ahsan, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 2658.
https://doi.org/10.1182/blood-2021-150641
Published: 2021
Journal Articles

Location of the t(4;14) Translocation Breakpoint Identifies a Subset of Newly-Diagnosed Multiple Myeloma Patients with Poor Prognosis

Nicholas Stong, Maria Ortiz, Fadi Towfic, William Pierceall, Erin Flynt, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 2681.
https://doi.org/10.1182/blood-2021-151094
Published: 2021