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Journal Articles

Dexamethasone dose intensity does not impact outcomes in newly diagnosed multiple myeloma: a secondary SWOG analysis

Clinical Trials & Observations
Rahul Banerjee, Rachael Sexton, Andrew J. Cowan, Aaron S. Rosenberg, Sikander Ailawadhi, S. Vincent Rajkumar, Shaji K Kumar, Angela Dispenzieri, Sagar Lonial, Brian G.M. Durie, Paul G. Richardson, Saad Z Usmani, Antje Hoering, Robert Z Orlowski
Journal: Blood
Blood blood.2024025939.
https://doi.org/10.1182/blood.2024025939
Published: 2024
Includes: Supplemental data
Journal Articles

Heme Attenuates T Cell Exhaustion and Drives Effector Function: Implications for Immune and Adoptive T Cell Therapy

Pulkit Gupta, Heather Lin, Remya Nair, Ruby Freeman, Dejah Blake, Kiran Lakhani, Doris R. Powell, Sagar Lonial, Benjamin G. Barwick, Ajay K. Nooka, Sarwish Rafiq, Mala Shanmugam
Journal: Blood
Blood (2023) 142 (Supplement 1): 6807.
https://doi.org/10.1182/blood-2023-186634
Published: 2023
Journal Articles

Prophylactic Tocilizumab to Prevent Cytokine Release Syndrome (CRS) with Teclistamab Administration

Ellen Marin, Sara Scott, Kathryn Maples, Nisha S. Joseph, Craig C. Hofmeister, Vikas A. Gupta, Madhav V. Dhodapkar, Jonathan L. Kaufman, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2023) 142 (Supplement 1): 2008.
https://doi.org/10.1182/blood-2023-189878
Published: 2023
Journal Articles

Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Therapy in High-Risk Newly Diagnosed Multiple Myeloma

Carlyn Tan, Neha Korde, Andriy Derkach, Malin Hultcrantz, Kylee H Maclachlan, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Alexander Lesokhin, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Craig C. Hofmeister, Jonathan L. Kaufman, Ajay K. Nooka, Saad Z Usmani, Sagar Lonial, Nisha S. Joseph
Journal: Blood
Blood (2023) 142 (Supplement 1): 1996.
https://doi.org/10.1182/blood-2023-190279
Published: 2023
Journal Articles

Efficacy of D-RVD Vs RVD Among t(11;14) Patients with Newly Diagnosed Myeloma

Jonathan L. Kaufman, Nisha S. Joseph, Vikas A. Gupta, Sara Dicamillo, Danielle Roberts, Craig C. Hofmeister, Madhav V. Dhodapkar, Ajay K. Nooka, Sagar Lonial, Lawrence H. Boise
Journal: Blood
Blood (2023) 142 (Supplement 1): 4699.
https://doi.org/10.1182/blood-2023-181783
Published: 2023
Journal Articles

RRMM and Post-BCMA Treated Subjects from the CC-220-MM-001 Study Show Increased Genomic Aberrations Associated with High-Risk and Significant Dysfunction in CD4+ T-Cell Compartment Compared to NDMM Subjects

Michael Amatangelo, Erin Flynt, Nicholas Stong, Maria Ortiz, Pradipta Ray, Maria Wang, Niels W.C.J. van de Donk, Sagar Lonial, Aparna Raval, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4665.
https://doi.org/10.1182/blood-2023-178912
Published: 2023
Journal Articles

Treatment Outcomes and Prognostic Factors with Lenalidomide, Bortezomib, and Dexamethasone (RVd) Alone Versus Rvd Plus Autologous Stem Cell Transplantation (ASCT) in African American (AA) Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) in the Determination Phase 3 Trial

Christiane A. Houde, Abdullah Khan, Susanna J. Jacobus, Hani Hassoun, Larry D. Anderson, Jr., Lauren E. Merz, Rebecca L. Zon, Yvonne Efebera, Tondre Buck, Racquel D. Innis-Shelton, Monique A Hartley-Brown, Sagar Lonial, Erica L. Campagnaro, Peter M. Voorhees, Robert Z. Orlowski, Edward Libby, David Duane Hurd, Caitlin L. Costello, Noopur S. Raje, Eva Medvedova, Philip L. McCarthy, Carter P. Milner, Cristina Gasparetto, Mounzer E Agha, Krisstina Gowin, Rammurti T. Kamble, Sundar Jagannath, Nitya Nathwani, Melissa Alsina, Sergio A. Giralt, Jacob P. Laubach, Omar Nadeem, Irene M. Ghobrial, Clifton C. Mo, Mehmet K. Samur, Kenneth C. Anderson, Nikhil C Munshi, Paul G. Richardson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4762.
https://doi.org/10.1182/blood-2023-181032
Published: 2023
Journal Articles

A Randomized Phase II Study of Daratumumab, Ixazomib, and Dexamethasone (DId, Arm A) Vs Daratumumab, Bortezomib and Dexamethasone (DVd) Followed By Daratumumab, Did (Arm B) in Newly Diagnosed Multiple Myeloma (DeRIVE) Study

Ajay K. Nooka, Nisha S. Joseph, Vikas A. Gupta, Craig C. Hofmeister, Madhav V. Dhodapkar, Bryan J Burton, Hafsa M Ahmed, Darrian Linton, Annelore Cortoos, Thomas S. Lin, Richard Labotka, Stephen J. Noga, Jonathan L. Kaufman, Sagar Lonial
Journal: Blood
Blood (2023) 142 (Supplement 1): 4764.
https://doi.org/10.1182/blood-2023-190871
Published: 2023
Journal Articles

Comparison of Response and Survival Outcomes in Standard- and High-Risk Newly Diagnosed Transplant-Eligible Multiple Myeloma (NDMM) Patients Treated with Lenalidomide, Bortezomib and Dexamethasone (RVD) Versus Daratumumab, Lenalidomide, Bortezomib and Dexamethasone (D-RVD)

Nisha S. Joseph, Jonathan L. Kaufman, Sara Dicamillo, Danielle Roberts, Vikas A. Gupta, Craig C. Hofmeister, Madhav V. Dhodapkar, Lawrence H. Boise, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2023) 142 (Supplement 1): 647.
https://doi.org/10.1182/blood-2023-187339
Published: 2023
Journal Articles

Impact of Dexamethasone (Dex) Dose Strength on Outcomes in Newly Diagnosed Multiple Myeloma (NDMM): A Secondary Analysis of SWOG Studies S0777 and S1211

Rahul Banerjee, Rachael Sexton, Andrew J. Cowan, Sikander Ailawadhi, S. Vincent Rajkumar, Shaji Kunnathu Kumar, Sagar Lonial, Bart Barlogie, Brian GM Durie, Saad Z Usmani, Antje Hoering, Robert Z. Orlowski
Journal: Blood
Blood (2023) 142 (Supplement 1): 1066.
https://doi.org/10.1182/blood-2023-181744
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma

Jesus G. Berdeja, David Dingli, Sagar Lonial, Andrew J. Yee, Alfred Chung, Cristina Gasparetto, P. Leif Bergsagel, Vivek Roy, Al-Ola Abdallah, Sharmilan Thanendrarajan, Aimaz Afrough, Laura Rosiñol, Suzanne Trudel, Paula Rodriguez Otero, Cyrille Touzeau, Pierre Bories, Soo Bang, Terry Connolly, Michelle Kim, Chad A. Lewis, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, Saad Z Usmani, Maria-Victoria Mateos, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2023-174550
Published: 2023
Journal Articles

Contemporary Multiple Myeloma Treatment Patterns Among HCPs and Concordance with Expert Recommendations: Analysis of an Interactive Online Decision Support Tool

Kelly G Brandt, Kristen Rosenthal, Shaji Kunnathu Kumar, Suzanne Lentzsch, Sagar Lonial, Saad Z Usmani, Timothy A. Quill, Joseph R. Mikhael
Journal: Blood
Blood (2023) 142 (Supplement 1): 7284.
https://doi.org/10.1182/blood-2023-180957
Published: 2023
Journal Articles

Mezigdomide (CC-92480), a Potent, Novel Cereblon E3 Ligase Modulator (CELMoD), Combined with Dexamethasone (DEX) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Preliminary Results from the Dose-Expansion Phase of the CC-92480-MM-001 Trial

Paul G. Richardson, Suzanne Trudel, Hang Quach, Rakesh Popat, Sagar Lonial, Robert Z. Orlowski, Kihyun Kim, María-Victoria Mateos, Charlotte Pawlyn, Karthik Ramasamy, Joaquín Martinez-Lopez, Alessia Spirli, Ignacio Casas-Avilés, Jing Gong, Michael Amatangelo, Jessica Katz, Paulo Maciag, Teresa Peluso, Nizar J. Bahlis
Journal: Blood
Blood (2022) 140 (Supplement 1): 1366–1368.
https://doi.org/10.1182/blood-2022-157945
Published: 2022
Journal Articles

Tumor-Immune Architecture and the Regulation of Antigen-Specific T-Cell Infiltration in Multiple Myeloma and Premalignant Plasma Cell Disorders

Hope Robinson, Nancy Villa, David L Jaye, Ajay K. Nooka, Alyssa Duffy, Samuel McCachren, Julia Manalo, Jeffrey M. Switchenko, Ava Horvat, Vaunita C Parihar, Jingjing Gong, Yan Liang, Geoffrey Smith, Vikas A Gupta, Lawrence H. Boise, Jonathan L. Kaufman, Craig C Hofmeister, Nisha Joseph, Sagar Lonial, Kavita Dhodapkar, Madhav Dhodapkar
Journal: Blood
Blood (2022) 140 (Supplement 1): 244–245.
https://doi.org/10.1182/blood-2022-169558
Published: 2022
Journal Articles

Single-Agent Belantamab Mafodotin in Patients with Relapsed or Refractory Multiple Myeloma: Final Analysis of the DREAMM-2 Trial

Ajay K. Nooka, Adam Cohen, Hans C. Lee, Ashraf Z. Badros, Attaya Suvannasankha, Natalie Callander, Al-Ola Abdallah, Suzanne Trudel, Ajai Chari, Edward Libby, Maria Chaudhry, Malin Hultcrantz, Martin Kortuem, Paul G. Richardson, Rakesh Popat, Douglas W. Sborov, Shawn Hakim, Eric Lewis, Bharat Bhushan, Boris Gorsh, Ira Gupta, Joanna Opalinska, Sagar Lonial
Journal: Blood
Blood (2022) 140 (Supplement 1): 7301–7303.
https://doi.org/10.1182/blood-2022-164877
Published: 2022
Journal Articles

Iberdomide (IBER) in Combination with Dexamethasone (DEX) in Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Anti-B-Cell Maturation Antigen (BCMA)-Exposed Cohort of the CC-220-MM-001 Trial

Sagar Lonial, Al-Ola Abdallah, Faiz Anwer, Ashraf Z. Badros, Manisha Bhutani, Abdullah Khan, Brea Lipe, Albert Oriol, Darrell White, Michael Amatangelo, Kexin Jin, Mark Masin, Vi Nguyen, Alpesh Amin, Paulo Maciag, Niels WCJ Van De Donk
Journal: Blood
Blood (2022) 140 (Supplement 1): 4398–4400.
https://doi.org/10.1182/blood-2022-158180
Published: 2022
Journal Articles

Phase 1 Trial of AUC-Targeted Melphalan in Myeloma Patients Undergoing Autologous Transplant (The MyMel Study)

Karen Sweiss, Pritesh Patel, Janet Guo, Kyeongmin Kim, Kasey Hill, Nicole Abbott, Jeremy Johnson, Donald Irby, John G. Quigley, Damiano Rondelli, R Donald Harvey, Ajay K. Nooka, Madhav Dhodapkar, Jonathan L. Kaufman, Nisha S. Joseph, Sagar Lonial, Douglas W. Sborov, Mitch A Phelps, Craig C Hofmeister
Journal: Blood
Blood (2022) 140 (Supplement 1): 5988–5990.
https://doi.org/10.1182/blood-2022-170778
Published: 2022
Journal Articles

Early and Sustained Undetectable Measurable Residual Disease (MRD) after Idecabtagene Vicleucel (ide-cel) Defines a Subset of Multiple Myeloma (MM) Patients in Karmma Achieving Prolonged Survival

Bruno Paiva, Irene Manrique, Julie A Rytlewski, Timothy B. Campbell, Christian Kazanecki, Nathan Martin, Shari M. Kaiser, Larry D. Anderson, Jr., Jesus Berdeja, Sagar Lonial, Noopur Raje, Yi Lin, Philippe Moreau, Jesús San-Miguel, Nikhil C Munshi
Journal: Blood
Blood (2022) 140 (Supplement 1): 2104–2105.
https://doi.org/10.1182/blood-2022-166658
Published: 2022
Journal Articles

Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)

Leon Bernal-Mizrachi, Ajay K. Nooka, Leonard Heffner, Craig E. Cole, Ravi Vij, J Christine Ye, Craig C Hofmeister, John Rushton, Zhengjia Chen, Subir Goyal, Munevver Cinar, Sagar Lonial, Jonathan L. Kaufman
Journal: Blood
Blood (2022) 140 (Supplement 1): 7311–7312.
https://doi.org/10.1182/blood-2022-170062
Published: 2022
Journal Articles

A Phase 2 Evaluation of Daratumumab-Based Induction Therapy in Multiple Myeloma Patients with Severe Renal Insufficiency

R Donald Harvey, Joseph K Franz, Nisha S. Joseph, Jonathan L. Kaufman, Elise Hitron, Hannah Collins, Catherine Braga, Ludimila Cavalcante, Kathryn T. Maples, Craig C Hofmeister, Madhav Dhodapkar, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2022) 140 (Supplement 1): 12633–12634.
https://doi.org/10.1182/blood-2022-157047
Published: 2022