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Journal Articles

Mezigdomide (MEZI) in Novel-Novel Combinations for Relapsed or Refractory Multiple Myeloma (RRMM): Preliminary Results from the CA057-003 Trial

Luciano J. Costa, Fredrik Schjesvold, Rakesh Popat, David Siegel, Saad Z. Usmani, Syed Abbas Ali, Michael P. Chu, Monique A. Hartley-Brown, Nizar J. Bahlis, Albert Oriol, Joaquín Martínez Lopez, Enrique M. Ocio, Karthik Ramasamy, Donna Reece, Emma Searle, Allison Gaudy, Antonina Kurtova, Wen Zhang, Rafael Sarmiento, August Dietrich, Jessica Katz, Michael Pourdehnad, Paul G. Richardson
Journal: Blood
Blood (2024) 144 (Supplement 1): 677.
https://doi.org/10.1182/blood-2024-198403
Published: 2024
Journal Articles

Ex Vivo Enriched Tumor Antigen-Specific T Cells Are Optimal Effectors of T Cell Engagers and Tumor-Specific T Cell Receptor/T Cell Engager Combination Provides Synergistic Efficacy Against Hematologic Malignancies

Manpreet Bariana, Mark Batistick, Mathias Oelke, Sojung Kim, Elena Cassella, Sidharth Anand, Shaina Anuncio, Ashley Varkey, Ruipeng Wang, Jack Ragheb, David Siegel, Johannes Zakrzewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 2056.
https://doi.org/10.1182/blood-2023-179342
Published: 2023
Journal Articles

Cost-Effectiveness Analysis of Motixafortide Versus Plerixafor in Stem Cell Mobilization for Autologous Transplantation in Patients with Multiple Myeloma

Mark Lamotte, John F. DiPersio, David Siegel, Haddas Meron, Laetitia Gerlier
Journal: Blood
Blood (2022) 140 (Supplement 1): 10794–10795.
https://doi.org/10.1182/blood-2022-166865
Published: 2022
Journal Articles

Effect of Daratumumab on Stem Cell Mobilization and Engraftment Kinetics Post Autologous Stem Cell Transplantation in Patients with Newly Diagnosed Multiple Myeloma

Samir Oza, Ronit Slotky, Pranay Vissa, Pooja Phull, Sukhdeep Kaur, Hyung C. Suh, Michele L. Donato, Scott D. Rowley, Noa Biran, David H. Vesole, David Siegel, Harsh Parmar
Journal: Blood
Blood (2022) 140 (Supplement 1): 10441–10442.
https://doi.org/10.1182/blood-2022-171098
Published: 2022
Journal Articles

The Clinical Characteristics and Epidemiology of Extramedullary Multiple Myeloma over the Past Two Decades

Ayrton Bangolo, Pierre Fwelo, Chinmay Trivedi, Jennifer Hashem, Parul Jandir, Katamon Klaichart, Rua Abdelrahim, Ayodya R Perera, Manbir Singh, Rohini B Gurumoorthy, Apurva Tiwari, Sudha S Konakanchi, Nagihan Orhun, Adithya Polavarapu, Ritika Sharma, Ankit Sarkar, Anupama Gupta, Bob-Hallen E. Treisma, Thin Thiri Soe, Ashwin Penchala, Sheetal Penmetsa, Srikar Bathi, Padmavathi Muppalla, David Siegel, Noa Biran, Harsh Parmar, David H. Vesole, Simcha Weissman, Pooja Phull
Journal: Blood
Blood (2022) 140 (Supplement 1): 12521–12522.
https://doi.org/10.1182/blood-2022-170783
Published: 2022
Journal Articles

Targeted Nanotherapy of Hematologic Malignancies Using Gold Nanoframework-Based Delivery of a Novel NF-Kb Inhibitor

Manpreet Bariana, Beilu Zhang, Jingyu Sun, Elena Cassella, Janice Rateshwar, Ming Tony Tan, Weiwei Wang, Jinping Wang, Rena Feinman, David Siegel, Hsiou-Chi Liou, Samedy Ouk, Patrizia Mondello, Hongjun Wang, Johannes Zakrzewski
Journal: Blood
Blood (2022) 140 (Supplement 1): 6018–6019.
https://doi.org/10.1182/blood-2022-160324
Published: 2022
Journal Articles

Outcomes of Patients with Heavily Pretreated Relapsed/Refractory Multiple Myeloma Receiving Salvage Cytotoxic Therapy with Supportive Stem Cell Boost

Ayrton Bangolo, Samir Oza, Ronit Slotky, Aimee Chappell, David Siegel, Harsh Parmar, Noa Biran, David H. Vesole, Pooja Phull
Journal: Blood
Blood (2022) 140 (Supplement 1): 10041–10042.
https://doi.org/10.1182/blood-2022-171012
Published: 2022
Journal Articles

Gut Microbiome Composition Is Associated with Engraftment Syndrome in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Rena Feinman, Ariel A. Aptekmann, Iriana Colorado, Samuel Roy, Joshua Zenreich, Sophia H. Dar, Adolfo Aleman, Rashmi Unawane, Margaret Zhuang, Megan Korkoleo, Mariefel Vendivil, Andrea Ricourt, Andrew McConnell, Phyllis McKiernan, Anqi Dai, Andrew L. Pecora, Noa Biran, David Siegel, Jonathan U. Peled, Michele L. Donato
Journal: Blood
Blood (2022) 140 (Supplement 1): 4843–4844.
https://doi.org/10.1182/blood-2022-168934
Published: 2022
Journal Articles

KarMMa-2 Cohort 2c: Efficacy and Safety of Idecabtagene Vicleucel in Patients with Clinical High-Risk Multiple Myeloma Due to Inadequate Response to Frontline Autologous Stem Cell Transplantation

Madhav Dhodapkar, Melissa Alsina, Jesus Berdeja, Krina Patel, Ravi Vij, Xavier Leleu, Anna Truppel-Hartmann, Debashree Basudhar, Ethan Thompson, Xirong Zheng, Revathi Ananthakrishnan, Linda Favre-Kontula, Chiara Greggio, Lars Sternas, David Siegel
Journal: Blood
Blood (2022) 140 (Supplement 1): 7441–7443.
https://doi.org/10.1182/blood-2022-162615
Published: 2022
Journal Articles

Carfilzomib vs bortezomib in patients with multiple myeloma and renal failure: a subgroup analysis of ENDEAVOR

Clinical Trials & Observations
Meletios Dimopoulos, David Siegel, Darrell J. White, Ralph Boccia, Karim S. Iskander, Zhao Yang, Amy S. Kimball, Khalid Mezzi, Heinz Ludwig, Ruben Niesvizky
Journal: Blood
Blood (2019) 133 (2): 147–155.
https://doi.org/10.1182/blood-2018-06-860015
Published: 2019
Includes: Supplemental data
Journal Articles

Safety and efficacy of selinexor in relapsed or refractory multiple myeloma and Waldenstrom macroglobulinemia

Clinical Trials & Observations
Christine Chen, David Siegel, Martin Gutierrez, Meagan Jacoby, Craig C. Hofmeister, Nashat Gabrail, Rachid Baz, Morten Mau-Sorensen, Jesus G. Berdeja, Michael Savona, Lynn Savoie, Suzanne Trudel, Nuchanan Areethamsirikul, T. J. Unger, Tami Rashal, Tim Hanke, Michael Kauffman, Sharon Shacham, Donna Reece
Journal: Blood
Blood (2018) 131 (8): 855–863.
https://doi.org/10.1182/blood-2017-08-797886
Published: 2018
Includes: Supplemental data
Journal Articles

Cyclophosphamide Based Regimens Compared to Plerixafor-Based Regimens for Stem Cell Mobilization in Patients with Multiple Myeloma Result in Higher CD34+ Cell Yield, Lower Cost and Similar Outcome Post Autologous Transplantation

Rima M Panchal, MD, Phyllis McKiernan, APN, MSN, David Siegel, MD PhD, Scott D. Rowley, MD, David H. Vesole, MD PhD, Tracy Andrews, PhD, Andrea Ortega, RN, Alan P Skarbnik, MD, Noa Biran, MD, Joshua R Richter, MD, Nino Aleksidze, MD, Andrew L. Pecora, MD, Andre Goy, MD, Maribel Pereiras, Pharm D, Michele L. Donato, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3283.
https://doi.org/10.1182/blood.V130.Suppl_1.3283.3283
Published: 2017
Journal Articles

Risk of Engraftment Syndrome after Autologous Stem Cell Transplantation for Multiple Myeloma Increases with Age and Lower Dose of CD34+ Cells, but Is Not Impacted By Immunomodulatory Chemotherapy

Phyllis McKiernan, APN, MSN, David Siegel, MD PhD, Scott D. Rowley, MD, David H. Vesole, MD PhD, Tracy Andrews, PhD, Andrea Ortega, RN, Alan P Skarbnik, MD, Noa Biran, MD, Joshua R Richter, MD, Andrew L. Pecora, MD, Andre Goy, MD, Rima M Panchal, MD, Nino Aleksidze, MD, Michele L. Donato, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3284.
https://doi.org/10.1182/blood.V130.Suppl_1.3284.3284
Published: 2017
Journal Articles

Preliminary Safety and Efficacy Data for Combined Checkpoint Inhibition with Ipilimumab (I) and Nivolumab (N) As Consolidation Following Autologous Stem Cell Transplantation (ASCT) for High-Risk Hematologic Malignancies - Cpit-001 Trial

Alan P Skarbnik, MD, Michele L. Donato, MD, Scott D. Rowley, MD, Andre Goy, MD, David H. Vesole, MD, Pashna N. Munshi, MD, David Siegel, MD PhD, Noa Biran, MD, Joshua R Richter, MD, Tatyana A Feldman, MD, Lori A. Leslie, MD, Mary E Dilorenzo, APN, Phyllis McKiernan, APN, MSN, Melissa Baker, MSN, ANP, Michele Boonstra, APN, Michele Simone, APN, Ann McNeill, ANP, Ernest Richards, PhD, Joshua Zenreich, Mariefel Vendivil, RN, Andrea Ortega, RN, Jacquelyn Callahan, RN, Michael B Atkins, MD, Andrew L. Pecora, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 340.
https://doi.org/10.1182/blood.V130.Suppl_1.340.340
Published: 2017
Journal Articles

Understanding the Preferences of Patients and Caregivers for Relapsed/Refractory Multiple Myeloma Treatment: A Mixed-Mode Patient-Centric Approach

Daniel Auclair, PhD, Carol Mansfield, PhD, Ajai Chari, MD, Craig E. Cole, MD, Mark A. Fiala, BS, Jonathan L. Kaufman, MD, Gregory Orloff, MD, David Siegel, MD PhD, Jeff A. Zonder, MD, Brennan Mange, Jennifer Yesil, MS, Mehul Dalal, PhD, Joseph Mikhael, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5662.
https://doi.org/10.1182/blood.V130.Suppl_1.5662.5662
Published: 2017
Journal Articles

Gene Expression Profiling (GEP) Is More Prognostic of OS and Post-ASCT PFS Compared to FISH in High-Risk Multiple Myeloma — a Single Center Experience

Miguel Gonzalez Velez, MD, Narjust Duma, MD, Badal Thakkar, MD MPH, Ning Dong, MD, Giselle Suero, MD PhD, David Siegel, MD PhD, Joshua R Richter, MD, David H. Vesole, MD PhD, Noa Biran, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5369.
https://doi.org/10.1182/blood.V130.Suppl_1.5369.5369
Published: 2017
Journal Articles

Outcomes of Autologous Stem Cell Transplantation in Very Elderly Patients with Multiple Myeloma

Phyllis McKiernan, APN, MSN, David Siegel, MD PhD, David H. Vesole, MD PhD, Scott D. Rowley, MD, Tracy Andrews, PhD, Andrea Ortega, RN, Alan P Skarbnik, MD, Noa Biran, MD, Joshua R Richter, MD, Andrew L. Pecora, MD, Andre Goy, MD, Rima M Panchal, MD, Nino Aleksidze, MD, Michele L. Donato, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2013.
https://doi.org/10.1182/blood.V130.Suppl_1.2013.2013
Published: 2017
Journal Articles

Immune Profile of Patients (pts) with Relapsed and/or Refractory Multiple Myeloma (RRMM) Treated with Pomalidomide (POM) + Low-Dose Dexamethasone (LoDEX) + Daratumumab (DARA) in the Second Line Immediately after Lenalidomide (LEN)

Xiaozhong Qian, Kathryn Newhall, PhD, Mark Tometsko, Chad Bjorklund, Jianglin Ma, Nizar J. Bahlis, MD, David Siegel, MD PhD, Gary J. Schiller, MD, Christy Samaras, Michael Sebag, MD PhD, Jesus G. Berdeja, MD, Siddhartha Ganguly, MD, Jeffrey V. Matous, MD, Kevin W Song, MD, Christopher S. Seet, Giampaolo Talamo, Shanthi Srinivas, Mirelis Acosta-Rivera, Michael Bar, Donald Quick, Bertrand Anz, Gustavo Fonseca, Donna Reece, MD FRCP(C), Jorge Mouro, MS, Amit Agarwal, MD PhD, Faiza Zafar, MPAS, Anjan Thakurta, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1888.
https://doi.org/10.1182/blood.V130.Suppl_1.1888.1888
Published: 2017
Journal Articles

Utility of Clinical-Grade Sequencing of Relapsed Multiple Myeloma Patients; Interim Analysis of the Multiple Myeloma Research Foundation (MMRF) Molecular Profiling Protocol

Daniel Auclair, PhD, Sikander Ailawadhi, Jesus G. Berdeja, MD, Xuhong Cao, Craig E. Cole, MD, Craig C Hofmeister, MDMPH, Sundar Jagannath, MD, Andrzej J. Jakubowiak, MD, Amrita Krishnan, MD, Shaji K Kumar, MD, Moshe Levy, MD, Sagar Lonial, MD, Gregory Orloff, MD, Dan Robinson, PhD, David Siegel, MD PhD, Suzanne Trudel, MD FRCP(C), Saad Z Usmani, MD, Ravi Vij, MDMBA, Jeffrey Lee Wolf, MD, Jennifer Yesil, MS, Jeffrey A Zonder, MD, Arul Chinnaiyan, MD, P. Leif Bergsagel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 395.
https://doi.org/10.1182/blood.V130.Suppl_1.395.395
Published: 2017
Journal Articles

Patients Responding to Any First Line Therapy for Multiple Myeloma Should Proceed to Autologous Stem Cell Transplantation Instead of Receiving Second Line Therapy to Deepen Response

Nino Aleksidze, MD, Phyllis McKiernan, APN, MSN, David Siegel, MD PhD, Scott D. Rowley, MD, David H. Vesole, MD PhD, Tracy Andrews, PhD, Andrea Ortega, RN, Alan P Skarbnik, MD, Noa Biran, MD, Joshua R Richter, MD, Andrew L. Pecora, MD, Andre Goy, MD, Rima M Panchal, MD, Michele L. Donato, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4538.
https://doi.org/10.1182/blood.V130.Suppl_1.4538.4538
Published: 2017