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Lars Sternas
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Journal Articles

KarMMa-2 Cohort 2a: Efficacy and Safety of Idecabtagene Vicleucel in Clinical High-Risk Multiple Myeloma Patients with Early Relapse after Frontline Autologous Stem Cell Transplantation

Saad Usmani, Krina Patel, Parameswaran Hari, Jesus Berdeja, Melissa Alsina, Ravi Vij, Noopur Raje, Xavier Leleu, Madhav Dhodapkar, Ran Reshef, Anna Truppel-Hartmann, Debashree Basudhar, Ethan Thompson, Xirong Zheng, Revathi Ananthakrishnan, Chiara Greggio, Linda Favre-Kontula, Lars Sternas, Jesús San-Miguel
Journal: Blood
Blood (2022) 140 (Supplement 1): 875–877.
https://doi.org/10.1182/blood-2022-162469
Published: 2022
Journal Articles

KarMMa-2 Cohort 2c: Efficacy and Safety of Idecabtagene Vicleucel in Patients with Clinical High-Risk Multiple Myeloma Due to Inadequate Response to Frontline Autologous Stem Cell Transplantation

Madhav Dhodapkar, Melissa Alsina, Jesus Berdeja, Krina Patel, Ravi Vij, Xavier Leleu, Anna Truppel-Hartmann, Debashree Basudhar, Ethan Thompson, Xirong Zheng, Revathi Ananthakrishnan, Linda Favre-Kontula, Chiara Greggio, Lars Sternas, David Siegel
Journal: Blood
Blood (2022) 140 (Supplement 1): 7441–7443.
https://doi.org/10.1182/blood-2022-162615
Published: 2022
Journal Articles

Correlative Analyses of Cereblon ( CRBN ), cMYC , IRF4 , BLIMP1 , and XBP1 with Clinical Outcomes in Stratus (MM-010), a Phase 3b Study of Pomalidomide (POM) + Low-Dose Dexamethasone (LoDEX) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)

Xiaozhong Qian, Meletios A. Dimopoulos, Michael Amatangelo, PhD, Chad Bjorklund, Katja C. Weisel, Enrique M. Ocio, MDPhD, Xin Yu, Teresa Peluso, Lars Sternas, Mohamed Zaki, Philippe Moreau, MDPhD, Anjan Thakurta, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3109.
https://doi.org/10.1182/blood.V130.Suppl_1.3109.3109
Published: 2017
Journal Articles

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

Clinical Trials & Observations
Meletios A. Dimopoulos, Antonio Palumbo, Paolo Corradini, Michele Cavo, Michel Delforge, Francesco Di Raimondo, Katja C. Weisel, Albert Oriol, Markus Hansson, Angelo Vacca, María Jesús Blanchard, Hartmut Goldschmidt, Chantal Doyen, Martin Kaiser, Mario Petrini, Pekka Anttila, Anna Maria Cafro, Reinier Raymakers, Jesus San-Miguel, Felipe de Arriba, Stefan Knop, Christoph Röllig, Enrique M. Ocio, Gareth Morgan, Neil Miller, Mathew Simcock, Teresa Peluso, Jennifer Herring, Lars Sternas, Mohamed H. Zaki, Philippe Moreau
Journal: Blood
Blood (2016) 128 (4): 497–503.
https://doi.org/10.1182/blood-2016-02-700872
Published: 2016
Journal Articles

An Updated Analysis of the Stratus Trial (MM-010): Safety and Efficacy of Pomalidomide Plus Low-Dose Dexamethasone (POM + LoDEX) in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM)

Meletios A. Dimopoulos, Antonio Palumbo, Paolo Corradini, Michele Cavo, Michel Delforge, Katja C. Weisel, Enrique M. Ocio, MD PhD, Francesco Di Raimondo, Markus Hansson, Mathew Simcock, Neil Miller, Ana Slaughter, Teresa Peluso, Lars Sternas, Mohamed H Zaki, Philippe Moreau
Journal: Blood
Blood (2015) 126 (23): 4225.
https://doi.org/10.1182/blood.V126.23.4225.4225
Published: 2015
Journal Articles

Analysis of Pomalidomide Plus Low-Dose Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma with Vs without Moderate Renal Impairment

David S Siegel, Katja C. Weisel, Meletios A. Dimopoulos, Rachid Baz, Paul G. Richardson, Michel Delforge, Kevin Song, Jesus San Miguel, MD PhD, Philippe Moreau, Xin Yu, Kevin Hong, Lars Sternas, Mohamed H Zaki, Antonio Palumbo
Journal: Blood
Blood (2015) 126 (23): 3031.
https://doi.org/10.1182/blood.V126.23.3031.3031
Published: 2015
Journal Articles

Pomalidomide + Low-Dose Dexamethasone in Patients with Refractory or Relapsed and Refractory Multiple Myeloma and Renal Impairment: Analysis of Patients from the Phase 3b Stratus Trial (MM-010)

Katja Weisel, MD, Meletios A. Dimopoulos, MD, Michele Cavo, MD, Enrique M. Ocio, MD PhD, Antonio Palumbo, MD, Paolo Corradini, MD PhD, Michel Delforge, MD PhF, Albert Oriol, MD, Harmut Goldschmidt, MD, Concetta Conticello, MD, Angelo Vacca, MD PhD, Markus Hansson, MD PhD, Neil Miller, CRS, Teresa Peluso, MBBS, Lars Sternas, MD, Mohamed H. Zaki, MD, Philippe Moreau, MD
Journal: Blood
Blood (2014) 124 (21): 4755.
https://doi.org/10.1182/blood.V124.21.4755.4755
Published: 2014
Journal Articles

Outcomes for Older Patients in Stratus (MM-010), a Single-Arm, and Phase 3b Study of Pomalidomide + Low-Dose Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma

Antonio Palumbo, MD, Meletios A. Dimopoulos, MD, Katja Weisel, MD, Michele Cavo, MD, Enrique M. Ocio, MD PhD, Paolo Corradini, MD PhD, Michel Delforge, MD PhF, Albert Oriol, MD, Hartmut Goldschmidt, MD, Maria Jesus Blanchard, MD, Concetta Conticello, MD, Angelo Vacca, MD PhD, Markus Hansson, MD PhD, Ana Slaughter, PhD, Mathew Simcock, MSc, Jennifer Herring, MD, Teresa Peluso, MBBS, Lars Sternas, MD, Mohamed H. Zaki, MD PhD, Philippe Moreau
Journal: Blood
Blood (2014) 124 (21): 4770.
https://doi.org/10.1182/blood.V124.21.4770.4770
Published: 2014
Journal Articles

MM-008: A Phase 1 Trial Evaluating Pharmacokinetics and Tolerability of Pomalidomide + Low-Dose Dexamethasone in Patients with Relapsed or Refractory and Refractory Multiple Myeloma and Renal Impairment

Jeffrey Matous, MD, David S Siegel, MD PhD, Sagar Lonial, MD, R. Donald Harvey, PharmD, Claudia Kasserra, PhD, Yan Li, PhD, Min Chen, PhD, Thomas Doerr, MSc, Lars Sternas, MD, Mohamed H. Zaki, MD, Christian Jacques, MD, Jatin J. Shah, MD
Journal: Blood
Blood (2014) 124 (21): 4730.
https://doi.org/10.1182/blood.V124.21.4730.4730
Published: 2014
Journal Articles

Pomalidomide Plus Low-Dose Dexamethasone (POM + LoDEX) for Relapsed and Refractory Multiple Myeloma (RRMM): Results from a Pharmacoeconomic Evaluation

Steve Schey, Sujith Dhanasiri, Dawn Lee, Lars Sternas, MD, Xin Yu, Mohamed H. Zaki, MD, Jamie Elvidge, Michael O'Dwyer
Journal: Blood
Blood (2014) 124 (21): 2649.
https://doi.org/10.1182/blood.V124.21.2649.2649
Published: 2014
Journal Articles

Safety and Efficacy in the Stratus (MM-010) Trial, a Single-Arm Phase 3b Study Evaluating Pomalidomide + Low-Dose Dexamethasone in Patients with Refractory or Relapsed and Refractory Multiple Myeloma

Meletios A. Dimopoulos, MD, Antonio Palumbo, MD, Katja Weisel, MD, Enrique M. Ocio, MD PhD, Michele Cavo, MD, Paolo Corradini, MD PhD, Michel Delforge, MD PhF, Albert Oriol, MD, Hartmut Goldschmidt, MD, María Jesús Blanchard, MD, Chantal Doyen, MD, Gareth J Morgan, MD PhD, Mathew Simcock, MSc, Neil Miller, CRS, Ana Slaughter, PhD, Teresa Peluso, MBBS, Lars Sternas, MD, Mohamed H. Zaki, MD PhD, Philippe Moreau, MD
Journal: Blood
Blood (2014) 124 (21): 80.
https://doi.org/10.1182/blood.V124.21.80.80
Published: 2014
Journal Articles

Efficacy and Safety Of Pomalidomide Plus Low-Dose Dexamethasone In Advanced Multiple Myeloma: Results Of Randomized Phase 2 and 3 Trials (MM-002/MM-003)

David S. Siegel, MD, PhD, Paul G. Richardson, MD, Meletios A. Dimopoulos, MD, Christine I. Chen, MD, Kevin Song, MD, Ravi Vij, MBBS, MD, Nizar J. Bahlis, MD, Rachid Baz, MD, Craig C Hofmeister, MD, Katja Weisel, MD, Sundar Jagannath, MD, Sagar Lonial, M.D., Michel Delforge, MD, PhD, Moshe Talpaz, MD, Philippe Moreau, MD, Jesus F San Miguel, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Anne Banos, MD, Albert Oriol, MD, Adrian Alegre, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina L Ivanova, MD, PhD, Joaquin Martinez-Lopez, Martha Q Lacy, MD, Min Chen, PhD, Philomena Casey, Lars Sternas, MD, Mohamed H. Zaki, MD, Christian J. Jacques, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2013) 122 (21): 3185.
https://doi.org/10.1182/blood.V122.21.3185.3185
Published: 2013
Journal Articles

Pomalidomide (POM) Plus Low-Dose Dexamethasone (LoDEX) Improves Health-Related Quality Of Life (HRQoL) Vs High-Dose Dexamethasone (HiDEX) In Relapsed Refractory Multiple Myeloma (RRMM) Patients Enrolled In MM-003 Phase 3 Randomized Trial

Kevin W. Song, MD, FRCPC, Meletios A. Dimopoulos, MD, Katja Weisel, MD, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Andrew Spencer, MD, Stefan Knop, MD, Christoph Renner, MD, Nizar J Bahlis, MD, Ramesh Amatya, PhD, Xin Yu, PhD, Mara Silvia Monzini, Lars Sternas, MD, Mohamed H. Zaki, MD, PhD, Christian J. Jacques, MD, Jesús F. San Miguel, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2939.
https://doi.org/10.1182/blood.V122.21.2939.2939
Published: 2013
Journal Articles

MM-008: A Phase 1 Trial Evaluating Pharmacokinetics and Tolerability Of Pomalidomide + Low-Dose Dexamethasone In Patients With Relapsed/Refractory Multiple Myeloma and Renal Impairment

Jeffrey Matous, MD, David S. Siegel, MD, PhD, Hien K. Duong, MD, Claudia Kasserra, PhD, Min Chen, PhD, Thomas Doerr, MSc, Lars Sternas, MD, Mohamed H. Zaki, MD, PhD, Christian Jacques, MD, Jatin J. Shah, M.D.
Journal: Blood
Blood (2013) 122 (21): 5393.
https://doi.org/10.1182/blood.V122.21.5393.5393
Published: 2013
Journal Articles

MM-003 Phase 3 Study Of Pomalidomide In Combination With Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM): POM + Lodex Is Beneficial For Elderly Patients (> 65 Years of Age)

Katja Weisel, MD, Jesús F. San Miguel, MD, PhD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina Ivanova, MD, PhD, Adrian Alegre, MD, Joaquin Martinez-Lopez, Christine I. Chen, MD, Stefan Knop, MD, Xin Yu, PhD, Latisha Watkins, Lars Sternas, MD, Christian Jacques, MD, Mohamed H. Zaki, MD, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2013) 122 (21): 3198.
https://doi.org/10.1182/blood.V122.21.3198.3198
Published: 2013
Journal Articles

Final Analysis, Cytogenetics, Long-Term Treatment, and Long-Term Survival In MM-003, A Phase 3 Study Comparing Pomalidomide + Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM)

Meletios A. Dimopoulos, MD, Katja Weisel, MD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina Ivanova, MD, PhD, Adrian Alegre, MD, Joaquin Martinez-Lopez, Christine I. Chen, MD, Andrew Spencer, MD, Stefan Knop, MD, Nizar J. Bahlis, MD, Christoph Renner, MD, Xin Yu, PhD, Kevin Hong, MS, Lars Sternas, MD, Christian Jacques, MD, Mohamed H. Zaki, MD, PhD, Jesús F. San Miguel, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 408.
https://doi.org/10.1182/blood.V122.21.408.408
Published: 2013
Journal Articles

Patient Outcomes By Prior Therapies and Depth Of Response: Analysis Of MM-003, a Phase 3 Study Comparing Pomalidomide + Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM)

Jesús F. San Miguel, MD, PhD, Katja Weisel, MD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina Ivanova, MD, PhD, Adrian Alegre, MD, Joaquin Martinez-Lopez, Christine I. Chen, MD, Christoph Renner, MD, Nizar J. Bahlis, MD, Xin Yu, PhD, Terri Teasdale, MS, Lars Sternas, MD, Christian Jacques, MD, Mohamed H. Zaki, MD, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2013) 122 (21): 686.
https://doi.org/10.1182/blood.V122.21.686.686
Published: 2013
Journal Articles

Pomalidomide in Combination with Low-Dose Dexamethasone: Demonstrates a Significant Progression Free Survival and Overall Survival Advantage, in Relapsed/Refractory MM: A Phase 3, Multicenter, Randomized, Open-Label Study

Meletios A. Dimopoulos, MD, Martha Q Lacy, MD, Philippe Moreau, MD, Katja C Weisel, MD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Anne Banos, MD, Albert Oriol, MD, Xin Yu, PhD, Lars Sternas, MD, Christian J. Jacques, MD, Mohamed Zaki, MD, Jesús F San Miguel, MD, PhD
Journal: Blood
Blood (2012) 120 (21): LBA-6.
https://doi.org/10.1182/blood.V120.21.LBA-6.LBA-6
Published: 2012