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Journal Articles

Immunogenic therapy: new actors in myeloma

Antonio G. Solimando, Angelo Vacca
Journal: Blood
Blood (2024) 143 (25): 2564–2565.
https://doi.org/10.1182/blood.2024024709
Published: 2024
Journal Articles

Adhesion-Mediated Multiple Myeloma (MM) Disease Progression: Junctional Adhesion Molecule a Enhances Angiogenesis and Multiple Myeloma Dissemination and Predicts Poor Survival

Antonio Giovanni Solimando, MD, Matteo Claudio Da Via', MD, Patrizia Leone, Giorgio Croci, Paola Borrelli, Paula Tabares Gaviria, Andreas Brandl, PhD, Giuseppe Di Lernia, Francesco Paolo Bianchi, Silvio Tafuri, Umair Munawar, MSc, Torsten Steinbrunn, Alessandra Balduini, MD, Assunta Melaccio, Hilka Rauert-Wunderlich, Katharina Schmiedgen, Hannah Manz, Paolo Ditonno, Roberto Ria, MD, Erik Henke, Carolina Terragna, Wolfram Klapper, Nora Trinks, Ulrich Terpitz, Giacomo Corleone, Leo Rasche, MD, Andreas Rosenwald, MD, Martin Kortuem, Michele Cavo, Domenico Ribatti, MD, Vito Racanelli, Hermann Einsele, MD, Angelo Vacca, MD PhD, Andreas Beilhack, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 855.
https://doi.org/10.1182/blood-2019-126674
Published: 2019
Journal Articles

The MP0250-CP201 Mirror Study: A Phase 2 Study Update of MP0250 Plus Bortezomib and Dexamethasone in Relapse/Refractory Multiple Myeloma (RRMM) Patients Previously Exposed to Proteasome Inhibitors and Immunomodulatory Drugs

Norbert Grząśko, MD PhD, Stefan Knop, Hartmut Goldschmidt, MD, Marc S Raab, MD PhD, Jan Dürig, Sara Bringhen, Mattia D'Agostino, MD, Barbara Gamberi, Elena Rivolti, MD, Angelo Vacca, MD PhD, Roberto Ria, MD, Artur Jurczyszyn, MD, Jorge Castellano Acosta, MD, Doris Lang, Guy Lemaillet, PhD, Bansod Sudhir, MD, Monika Szarejko, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1899.
https://doi.org/10.1182/blood-2019-129827
Published: 2019
Journal Articles

MP0250 Combined with Bortezomib and Dexamethasone in Multiple Myeloma Patients Previoulsy Exposed to Proteasome Inhibitors and Immunomodulatory Drugs

Stefan Knop, Hartmut Goldschmidt, MD, Marc S Raab, MD PhD, Monika Szarejko, Artur Jurczyszyn, MD, Jan Dürig, Sara Bringhen, Barbara Gamberi, MD, Angelo Vacca, Jorge Castellano Acosta, MD, Guy Lemaillet, PhD, Cedric Cortijo, PhD, Bansod Sudhir, Norbert Grząśko, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1980.
https://doi.org/10.1182/blood-2018-99-112859
Published: 2018
Journal Articles

Central Function for JAM-a in Multiple Myeloma Patients with Extramedullary Disease

Antonio Giovanni Solimando, MD, Matteo Claudio Da Via', MD, Paola Borrelli, Patrizia Leone, Giuseppe Di Lernia, Paula Tabares Gaviria, Andreas Brandl, PhD, Giacinto Luca Pedone, Hilka Rauert-Wunderlich, Constantin Lapa, MD, Silvio Tafuri, Francesco Paolo Bianchi, Roberto Ria, MD, Max Bittrich, MD, Domenico Ribatti, MD, Andreas Rosenwald, K. Martin Kortüm, MD, Vito Racanelli, Angelo Vacca, MD PhD, Hermann Einsele, MD, Andreas Beilhack, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4455.
https://doi.org/10.1182/blood-2018-99-117021
Published: 2018
Journal Articles

Soluble CX3CL1/Fractalkine Is a New Player in the Pro-Inflammatory Microenvironment of Multiple Myeloma Patients Related to Bone Marrow Plasma Cell Infiltration and Neo-Vascularization

Anna Corcione, Valentina Marchica, Elisa Ferretti, Denise Toscani, PhD, Marina Bolzoni, PhD, Federica Costa, PhD, Cristina Mancini, MD, Eugenia Martella, MD, Fabrizio Accardi, MD, Laura Notarfranchi, MD, Domenico Ribatti, MD, Angelo Vacca, MD PhD, Franco Aversa, MD, Vito Pistoia, MD, Nicola Giuliani, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3044.
https://doi.org/10.1182/blood.V130.Suppl_1.3044.3044
Published: 2017
Journal Articles

JAM-A as a Prognostic Factor and New Therapeutic Target in Multiple Myeloma

Antonio Solimando, MD, Andreas Brandl, PhD, Mattenheimer Katharina, Carolin Graf, Miriram Ritz, Anna Ruckdeschel, Thorsten Stühmer, PhD, Martina Rudelius, MD, Maria Antonia Frassanito, PhD, Rosenwald Andreas, MD, Franz Jakob, MD, Angelo Vacca, MD, Hermann Einsele, MD, Andreas Beilhack, MD
Journal: Blood
Blood (2016) 128 (22): 307.
https://doi.org/10.1182/blood.V128.22.307.307
Published: 2016
Journal Articles

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

Clinical Trials & Observations
Meletios A. Dimopoulos, Antonio Palumbo, Paolo Corradini, Michele Cavo, Michel Delforge, Francesco Di Raimondo, Katja C. Weisel, Albert Oriol, Markus Hansson, Angelo Vacca, María Jesús Blanchard, Hartmut Goldschmidt, Chantal Doyen, Martin Kaiser, Mario Petrini, Pekka Anttila, Anna Maria Cafro, Reinier Raymakers, Jesus San-Miguel, Felipe de Arriba, Stefan Knop, Christoph Röllig, Enrique M. Ocio, Gareth Morgan, Neil Miller, Mathew Simcock, Teresa Peluso, Jennifer Herring, Lars Sternas, Mohamed H. Zaki, Philippe Moreau
Journal: Blood
Blood (2016) 128 (4): 497–503.
https://doi.org/10.1182/blood-2016-02-700872
Published: 2016
Journal Articles

Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8 + T-cell killing

Patrizia Leone, Simona Berardi, Maria Antonia Frassanito, Roberto Ria, Valli De Re, Sebastiano Cicco, Stefano Battaglia, Paolo Ditonno, Franco Dammacco, Angelo Vacca, Vito Racanelli
Journal: Blood
Blood (2015) 126 (12): 1443–1451.
https://doi.org/10.1182/blood-2015-01-623975
Published: 2015
Journal Articles

Pomalidomide + Low-Dose Dexamethasone in Patients with Refractory or Relapsed and Refractory Multiple Myeloma and Renal Impairment: Analysis of Patients from the Phase 3b Stratus Trial (MM-010)

Katja Weisel, MD, Meletios A. Dimopoulos, MD, Michele Cavo, MD, Enrique M. Ocio, MD PhD, Antonio Palumbo, MD, Paolo Corradini, MD PhD, Michel Delforge, MD PhF, Albert Oriol, MD, Harmut Goldschmidt, MD, Concetta Conticello, MD, Angelo Vacca, MD PhD, Markus Hansson, MD PhD, Neil Miller, CRS, Teresa Peluso, MBBS, Lars Sternas, MD, Mohamed H. Zaki, MD, Philippe Moreau, MD
Journal: Blood
Blood (2014) 124 (21): 4755.
https://doi.org/10.1182/blood.V124.21.4755.4755
Published: 2014
Journal Articles

Outcomes for Older Patients in Stratus (MM-010), a Single-Arm, and Phase 3b Study of Pomalidomide + Low-Dose Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma

Antonio Palumbo, MD, Meletios A. Dimopoulos, MD, Katja Weisel, MD, Michele Cavo, MD, Enrique M. Ocio, MD PhD, Paolo Corradini, MD PhD, Michel Delforge, MD PhF, Albert Oriol, MD, Hartmut Goldschmidt, MD, Maria Jesus Blanchard, MD, Concetta Conticello, MD, Angelo Vacca, MD PhD, Markus Hansson, MD PhD, Ana Slaughter, PhD, Mathew Simcock, MSc, Jennifer Herring, MD, Teresa Peluso, MBBS, Lars Sternas, MD, Mohamed H. Zaki, MD PhD, Philippe Moreau
Journal: Blood
Blood (2014) 124 (21): 4770.
https://doi.org/10.1182/blood.V124.21.4770.4770
Published: 2014
Journal Articles

Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans

Arianna Calcinotto, Maurilio Ponzoni, Roberto Ria, Matteo Grioni, Elena Cattaneo, Isabella Villa, Maria Teresa Sabrina Bertilaccio, Marta Chesi, PhD, Alessandro Rubinacci, Giovanni Tonon, MDPhD, Peter Leif Bergsagel, MD PhD, Angelo Vacca, MD PhD, Matteo Bellone, MD
Journal: Blood
Blood (2014) 124 (21): 5678.
https://doi.org/10.1182/blood.V124.21.5678.5678
Published: 2014
Journal Articles

Cancer Associated Fibroblasts in Multiple Myeloma: The Urokinase Receptor System in Tumor Growth Regulation

Simona Serratì, Carla Minoia, Anastasia Chilla, Anna Laurenzana, Francesca Margheri, Maria Antonia Frassanito, Nicola Sgherza, Giacoma De Tullio, Angelo Vacca, MD PhD, Pasquale Iacopino, MD, Mario Del Rosso, Gabriella Fibbi, Attilio Guarini
Journal: Blood
Blood (2014) 124 (21): 5687.
https://doi.org/10.1182/blood.V124.21.5687.5687
Published: 2014
Journal Articles

EphA3 As a Molecular Target In Multiple Myeloma: Opportunity For a Novel Therapeutic Approach With a Specific Monoclonal Antibody

Antonella Caivano, Francesco La Rocca, Ilaria Laurenzana, Alessandra Favole, PhD, Irma Airoldi, PhD, Emma Di Carlo, MD, PhD, Valentina Gaidano, Enrico Bracco, PhD, Oreste Villani, Giuseppe Pietrantuono, Luciana De Luca, Annalisa Morano, Vittorio Simeon, Stefania Trino, Simona Berardi, Antonio Basile, Martin Lackmann, PhD, Angelo Vacca, MD, PhD, Pellegrino Musto, MD, Francesco Frassoni, Daniela Cilloni
Journal: Blood
Blood (2013) 122 (21): 3211.
https://doi.org/10.1182/blood.V122.21.3211.3211
Published: 2013
Journal Articles

Identification of EpHA3 As a New Potential Molecular Target in Multiple Myeloma.

Antonella Caivano, Francesco La Rocca, Alessandra Favole, PhD, Sonia Carturan, PhD, Enrico Bracco, PhD, Oreste Villani, Giuseppe Pietrantuono, Ilaria Laurenzana, Luciana De Luca, MD, Annalisa Morano, Vittorio Simeon, Stefania Trino, Simona Berardi, Antonio Basile, Angelo Vacca, Pellegrino Musto, Daniela Cilloni, MD
Journal: Blood
Blood (2012) 120 (21): 2926.
https://doi.org/10.1182/blood.V120.21.2926.2926
Published: 2012
Journal Articles

Salvage Treatment with Lenalidomide and Dexamethasone In Patients with Relapsed Refractory Mantle Cell Lymphoma: Clinical Results and Modifications of Angiogenic Biomarkers

Francesco Zaja, Stefano De Luca, Umberto Vitolo, Lorella Orsucci, Alessandro Levis, Flavia Salvi, Chiara Rusconi, Erika Ravelli, Alessandra Tucci, Chiara Bottelli, Monica Balzarotti, Armando Santoro, Ercole Brusamolino, Maurizio Bonfichi, Alice Di Rocco, Caterina Stelitano, Luca Baldini, Stefano A. Pileri, Stefano Volpetti, Fabio Saccona, Gianni Ciccone, Antonella Ferranti, Ivana Catacchio, Roberto Ria, Angelo Vacca, Renato Fanin
Journal: Blood
Blood (2010) 116 (21): 966.
https://doi.org/10.1182/blood.V116.21.966.966
Published: 2010
Journal Articles

Hypoxia-Inducible Factor-1 in Multiple Myeloma Progression.

Roberto Ria, Antonia Reale, Simona Berardi, Claudia Piccoli, Giulia Di Pietro, Antonio Basile, Nazareno Capitanio, Angelo Vacca
Journal: Blood
Blood (2009) 114 (22): 1812.
https://doi.org/10.1182/blood.V114.22.1812.1812
Published: 2009
Journal Articles

Identification of Novel Angiogenic Proteins in Multiple Myeloma Patient-Derived Endothelial Cells Using Proteome-Wide Analysis.

Roberto Ria, Simona Berardi, Antonia Reale, Giulia Di Pietro, Antonio Basile, Rosa Terracciano, Rocco Savino, Angelo Vacca
Journal: Blood
Blood (2009) 114 (22): 2825.
https://doi.org/10.1182/blood.V114.22.2825.2825
Published: 2009
Journal Articles

MicroRNAs to know in Waldenström macroglobulinemia

Angelo Vacca, Franco Dammacco
Journal: Blood
Blood (2009) 113 (18): 4133–4134.
https://doi.org/10.1182/blood-2009-01-199828
Published: 2009
Journal Articles

Validation of PDGFRβ and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib

Addolorata Maria Luce Coluccia, Teresa Cirulli, Paola Neri, Domenica Mangieri, Maria Cristina Colanardi, Antonio Gnoni, Nicola Di Renzo, Franco Dammacco, Pierfrancesco Tassone, Domenico Ribatti, Carlo Gambacorti-Passerini, Angelo Vacca
Journal: Blood
Blood (2008) 112 (4): 1346–1356.
https://doi.org/10.1182/blood-2007-10-116590
Published: 2008