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Journal Articles

Isatuximab, Pomalidomide, and Dexamethasone (IsaPd) As Salvage Therapy for Patients with Multiple Myeloma: Multicenter, Retrospective Clinical Experience with 262 Cases Outside of Controlled Clinical Trials

Enrica Antonia Martino, Daniele Derudas, Elena Rossi, Sofia Terlizzi, Giovanni Reddiconto, Paola Stefanoni, Jacopo Micozzi, Silvia Mangiacavalli, Elena Zamagni, Massimo Offidani, Anna Furlan, Gabriele Buda, Sr., Flavia Lotti, Carmine Liberatore, Antonio Lazzaro, Roberta Della Pepa, Giuseppe Bertuglia, Emiliano Barbieri, Concetta Conticello, Claudio De Magistris, Lorenzo De Paoli, Velia Bongarzoni, Anna Maria Cafro, Anna Mele, Pietro Benvenuti, Claudio Cerchione, Cirino Botta, Elisabetta Antonioli, Nicola Sgherza, Sara Aquino, Giuseppe Mele, Gregorio Barila, Salvatore Palmieri, Ombretta Annibali, Rosario Bianco, Massimiliano Arangio Febbo, Gloria Margiotta Casaluci, Angela Rago, Raffaele Fontana, Francesca Farina, Ernesto Vigna, Antonella Bruzzese, Catello Califano, Angela Amendola, Daniela Roccotelli, Alessandra Lombardo, Annalisa Citro, Giuseppina Uccello, Renato Zambello, Alessandro Maggi, Santo Neri, Michele Monachesi, Alessandro Gozzetti, Vittorio Montefusco, Marino Brunori, Nicola Di Renzo, Marta Coscia, Valerio De Stefano, Antonino Neri, Francesco Di Raimondo, Fortunato Morabito, Pellegrino Musto, Massimo Gentile
Journal: Blood
Blood (2024) 144 (Supplement 1): 4699.
https://doi.org/10.1182/blood-2024-206008
Published: 2024
Journal Articles

Pomalidomide, Bortezomib and Dexamethasone in Multiple Myeloma Patients Double Refractory to Lenalidomide and Anti-CD38 Monoclonal Antibodies: A Multicentric Italian Retrospective Study

Carmine Liberatore, Paola Tacchetti, Concetta Conticello, Gregorio Barila, Elisabetta Antonioli, Angelo Belotti, Anna Maria Cafro, Laura Paris, Velia Bongarzoni, Massimo Gentile, Matteo DA VIA, Barbara Gamberi, Sara Pezzatti, Fabrizio Ciambelli, Mariagrazia Garzia, Ombretta Annibali, Francesca Fazio, Giusy Antolino, Nicola Sgherza, Francesca Farina, Annalisa Citro, Monica Galli, Vittorio Del Fabro, Claudio Salvatore Cartia, Francesca Fioritoni, Katia Mancuso, Irene Attucci, Maria Luisa Pioltelli, Michele Puppi, Sofia Terlizzi, Chiara Lisi, Virginia Valeria Ferretti, Massimo Offidani, Maria Teresa Petrucci, Silvia Mangiacavalli
Journal: Blood
Blood (2024) 144 (Supplement 1): 5153.
https://doi.org/10.1182/blood-2024-204021
Published: 2024
Journal Articles

Salvage Autologous Stem Cell Transplant for the Treatment of First Relapse Multiple Myeloma: Evidence of Its Clinical Role from a Multicenter Italian Study

Silvia Mangiacavalli, Daniele Derudas, Angelo Belotti, Elena Zamagni, Laura Paris, Vincenzo Pavone, Roberto Mina, Nicola Di Renzo, Francesca Fazio, Giuseppe Tarantini, Sara Pezzatti, Gaetano Palumbo, Magda Marcatti, Jolanda Donatella Vincelli, Anna Maria Cafro, Antonietta Pia Falcone, Renato Zambello, Concetta Conticello, Rita Mazza, Francesco Di Raimondo, Alessandra Pompa, Enrica Antonia Martino, Fortunato Morabito, Paola Stefanoni, Gregorio Barila, Francesca Farina, Claudio Salvatore Cartia, Andrea Casson, Virginia Ferretti, Eleonora Fresi, Luca Arcaini, Maria Teresa Petrucci, Massimo Gentile
Journal: Blood
Blood (2023) 142 (Supplement 1): 2226.
https://doi.org/10.1182/blood-2023-181233
Published: 2023
Journal Articles

Carfilzomib-Lenalidomide-Dexamethasone (KRd) Vs. Lenalidomide-Dexamethasone (Rd) in Newly Diagnosed Fit or Intermediate-Fit Multiple Myeloma Patients Not Eligible for Autologous Stem-Cell Transplantation (Phase III EMN20 Trial): Analysis of Sustained Undetectable Minimal Residual Disease (MRD)

Sara Bringhen, Elisabetta Antonioli, Barbara Gamberi, Benedetto Bruno, Daniele Derudas, Patrizia Tosi, Francesca Fazio, Rita Mazza, Sonia Ronconi, Paolo Corradini, Flavia Lotti, Claudia Cellini, Antonietta Pia Falcone, Piero Galieni, Roberto Ria, Angelo Belotti, Donato Mannina, Anna Maria Cafro, Clotilde Cangialosi, Iolanda Donatella Vincelli, Alessandra Lombardo, Alessandra Larocca, Mario Boccadoro, Mattia D'Agostino
Journal: Blood
Blood (2023) 142 (Supplement 1): 205.
https://doi.org/10.1182/blood-2023-177673
Published: 2023
Journal Articles

Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analysis

Gianluca Cavallaro, Monica Galli, Laura Paris, Paola Stefanoni, Chiara Pavoni, Silvia Mangiacavalli, Valeria Masoni, Michele Palumbo, Alessandra Pompa, Anna Maria Cafro, Sara Pezzatti, Stefano Crippa, Alessandro Rambaldi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4706.
https://doi.org/10.1182/blood-2023-185907
Published: 2023
Journal Articles

Initial Results from a Phase 1 Dose-Escalation Study of WVT078, a BCMA×CD3 Bispecific Antibody, in Combination with WHG626, a Gamma-Secretase (GS) Inhibitor, in Patients with Relapsed and/or Refractory Multiple Myeloma

Fredrik Schjesvold, Andrew Spencer, Yael C. Cohen, Enrique M Ocio, Jordi López-Pardo, Anna Maria Cafro, Natalie S. Callander, Jonathan L. Kaufman, Meera Mohan, Martin Wermke, Noriko Doki, Rebecca Kan, Karolina Kulec, Gina Trabucco, Stan Ye, Romain Sechaud, Cornelia Quadt, Raghav Chawla, Marc S. Raab
Journal: Blood
Blood (2023) 142 (Supplement 1): 4752.
https://doi.org/10.1182/blood-2023-177908
Published: 2023
Journal Articles

Dedalo: Phase II Study of Daratumumab Plus Pomalidomide and Dexamethasone (DPd) in Patients with Relapsed/Refractory Multiple Myeloma and 17p Deletion

Vittorio Montefusco, Anna Maria Cafro, Gloria Margiotta Casaluci, Francesca Patriarca, Roberto Mina, Mattia D'Agostino, Andrea Capra, Claudia Priola, Anna Benedetta Dalla Palma, Rita Rizzi, Angelo Genua, Maria Teresa Petrucci, Laura Paris, Angelo Belotti, Michele Cavo, Concetta Conticello, Carmelo Carlo-Stella, Mario Boccadoro
Journal: Blood
Blood (2022) 140 (Supplement 1): 10193–10195.
https://doi.org/10.1182/blood-2022-156691
Published: 2022
Journal Articles

Real-World Patterns of Utilization and Outcome of Market Approved Lenalidomide-Based Triplet Combinations in First Relapsed Multiple Myeloma Patients: Evidence from a Propensity Score Matched Analysis

Silvia Mangiacavalli, Monica Galli, Sara Pezzatti, Angelo Belotti, Francesca Fazio, Magda Marcatti, Anna Maria Cafro, Roberto Mina, Renato Zambello, Laura Paris, Claudio Salvatore Cartia, Gregorio Barilà, Cecilia Olivares, Alessandra Pompa, Rita Mazza, Francesca Farina, Martina Soldarini, Pietro Benvenuti, Marica Lecci, Virginia Valeria Ferretti, Maria Teresa Petrucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 4109.
https://doi.org/10.1182/blood-2021-146908
Published: 2021
Journal Articles

Consolidation Treatment with VRD Followed By Maintenance Therapy Versus Maintenance Alone in Newly Diagnosed, Transplant-Eligible Patients with Multiple Myeloma (MM): A Randomized Phase 3 Trial of the European Myeloma Network (EMN02/HO95)

Pieter Sonneveld, MD PhD, Meral Beksac, MD, Bronno Van Der Holt, PhD, Meletios A Dimopoulos, Angelo Michele Carella, MD, Heinz Ludwig, MD, Sonja Zweegman, MD PhD, Thilo Zander, MD, Ruth Wester, MD, Roman Hajek, MD, Lucia Pantani, MD PhD, Luca Dozza, MSc, Francesca Gay, MD, Anna Maria Cafro, Luca De Rosa, Francesca Fioritoni, MD, Ulf-Henrik Mellqvist, MD PhD, Rossella Troia, PharmD, Niels Frost Andersen, MD PhD, Ka Lung Wu, MD PhD, Christoph Driessen, MD, Susana Carvalho, MD, Alexandra J. Croockewit, MD PhD, Fredrik Schjesvold, MDPhD, Massimo Offidani, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–48.
https://doi.org/10.1182/blood-2020-139337
Published: 2020
Journal Articles

Tumor Circulating Plasma Cells Detected By Flow Cytometric Single Platform Method Correlate with Clinical Response to Therapy and Unfavorable Patients' Characteristics

Vittorio Emanuele Muccio, Milena Gilestro, Elona Saraci, Andrea Capra, Alessandro Costa, Marina Ruggeri, Simona Caltagirone, Daniela Oddolo, Chiara Mussatto, Pellegrino Musto, Lucia Pantani, Vincenzo Pavone, Sonia Ronconi, Iolanda Donatella Vincelli, Anna Maria Cafro, Claudia Cellini, Vanessa Innao, Eugenio Piro, Francesca Gay, MD, Mario Boccadoro, Paola Omedé
Journal: Blood
Blood (2019) 134 (Supplement_1): 4357.
https://doi.org/10.1182/blood-2019-122657
Published: 2019
Journal Articles

Carfilzomib-Lenalidomide-Dexamethasone (KRd) Induction-Autologous Transplant (ASCT)-Krd Consolidation Vs KRd 12 Cycles Vs Carfilzomib-Cyclophosphamide-Dexamethasone (KCd) Induction-ASCT-KCd Consolidation: Analysis of the Randomized Forte Trial in Newly Diagnosed Multiple Myeloma (NDMM)

Francesca Gay, MD, Chiara Cerrato, MD, Delia Rota Scalabrini, MD, Monica Galli, MD, Angelo Belotti, MD, Elena Zamagni, MD, Antonio Ledda, MD, Mariella Grasso, MD, Emanuele Angelucci, MD, Anna Marina Liberati, MD, Patrizia Tosi, MD, Francesco Pisani, MD, Stefano Spada, Ombretta Annibali, MD, Anna Baraldi, MD, Paola Omedé, Piero Galieni, MD, Rita Rizzi, MD, Norbert Pescosta, MD, Sonia Ronconi, MD, Donatella Vincelli, MD, Anna Maria Cafro, MD, Massimo Offidani, MD, Antonio Palumbo, MD, Pellegrino Musto, MD, Michele Cavo, MD, Mario Boccadoro, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 121.
https://doi.org/10.1182/blood-2018-99-112093
Published: 2018
Journal Articles

Bortezomib/Cyclophosphamide/Dexamethasone Versus Lenalidomide/Cyclophosphamide/Dexamethasone in Multiple Myeloma Patients at First Relapse: Final Results of a Phase III Study

Vittorio Montefusco, MD, Alessandro Corso, MD, Monica Galli, MD PhD, Elena Tagliabue, Sara Pezzatti, Francesca Patriarca, MD, Filippo Gherlinzoni, MD, Renato Zambello, MD, Simona Sammassimo, Magda Marcatti, MD, Andrea Nozza, Claudia Crippa, MD, Anna Maria Cafro, MD, Luca Baldini, Paolo Corradini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 836.
https://doi.org/10.1182/blood.V130.Suppl_1.836.836
Published: 2017
Journal Articles

Double Autologous Stem Cell Transplantation Significantly Prolongs Progression-Free Survival and Overall Survival in Comparison with Single Autotransplantation in Newly Diagnosed Multiple Myeloma: An Analysis of Phase 3 EMN02/HO95 Study

Michele Cavo, MD, Francesca Maria Gay, Francesca Patriarca, MD, Elena Zamagni, MD, Vittorio Montefusco, MD, Luca Dozza, Monica Galli, MD PhD, Sara Bringhen, Nicoletta Testoni, BSc, Mariella Grasso, MD, Stelvio Ballanti, MD, Paola Tacchetti, MD, Giampietro Semenzato, MD, Anna Marina Liberati, Giulia Benevolo, Mauro Spriano, MD, Paolo Di Bartolomeo, MD, Tommaso Caravita di Toritto, MD, Angelo D. Palmas, MD, Anna Maria Cafro, MD, Fortunato Morabito, MD, Pellegrino Musto, MD, Rita Rizzi, MD, Antonio Palumbo, MD, Pieter Sonneveld, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 401.
https://doi.org/10.1182/blood.V130.Suppl_1.401.401
Published: 2017
Journal Articles

Bortezomib-Dexamethasone Re-Treatment at Biochemical Relapse Vs Observation in Relapsed/Refractory Multiple Myeloma Patients: Results of a Phase II Multi-Center, Randomized Study

Roberto Mina, MD, Alessandra Larocca, Angelo Belotti, MD, Francesco Di Raimondo, MD, Anna Baraldi, MD, Massimo Offidani, MD, Monia Marchetti, MD, Roberto Ria, MD, Annarita Conconi, MD, Norbert Pescosta, MD, Mariella Grasso, MD, Giusy Cetani, MD, Anna Maria Cafro, MD, Roberto Passera, Rossella Troia, Gianpietro Semenzato, MD, Nicola Giuliani, MD PhD, Stelvio Ballanti, MD, Claudia Cellini, MD, Anna Marina Liberati, Tommaso Caravita di Toritto, MD, Maria Teresa Petrucci, MD, Pellegrino Musto, MD, Antonio Palumbo, MD, Pieter Sonneveld, MDPhD, Mario Boccadoro, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3128.
https://doi.org/10.1182/blood.V130.Suppl_1.3128.3128
Published: 2017
Journal Articles

A Multicenter, Open Label Phase I/II Study of Carfilzomib, Pomalidomide and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma (MM) Patients

Sara Bringhen, MD, Valeria Magarotto, MD, Anna Marina Liberati, MD, Angelo Belotti, MD, Alessandra Larocca, MD, Milena Gilestro, BSc, Francesca Bonello, MD, Gianluca Gaidano, MD PhD, Paola Bertazzoni, MD, Raffaella Stocchi, MD, Rossella Ribolla, MD, Chiara Di Sano, MD, Francesca Patriarca, Roberto Passera, PharmD, PhD, Lorenzo De Paoli, MD, Stefania Oliva, MD, Anna Maria Cafro, MD, Pieter Sonneveld, MD PhD, Antonio Palumbo, MD, Mario Boccadoro, MD
Journal: Blood
Blood (2016) 128 (22): 1145.
https://doi.org/10.1182/blood.V128.22.1145.1145
Published: 2016
Journal Articles

Impact of Treatment Intensification According to Patient Prognosis: A Pooled Analysis of 3 Randomized Phase III Trials

Francesca Gay, MD, Mattia D'Agostino, MD, Roman Hajek, prof, MD PhD, Sara Bringhen, MD, Concetta Conticello, MD, Gianluca Gaidano, MD PhD, Vittorio Montefusco, Sara Pezzatti, MD, Marco Salvini, MD, Tommaso Caravita, MD, Anna Maria Cafro, MD, Michele Cavo, MD, Marina Ruggeri, Fortunato Morabito, MD, Roberto Mina, MD, Luca Baldini, MD Prof, Giulia Benevolo, MD, Tommasina Guglielmelli, MD, Annalisa Bernardini, Roberto Foà, MD, Francesca Patriarca, MD, Massimo Offidani, MD, Roberto Ria, MD, Dina Ben Yehuda, MD, Maria Teresa Petrucci, MD, Andrew Spencer, MD, Antonio Palumbo, MD, Mario Boccadoro, MD
Journal: Blood
Blood (2016) 128 (22): 995.
https://doi.org/10.1182/blood.V128.22.995.995
Published: 2016
Journal Articles

Consolidation Followed By Maintenance Therapy Versus Maintenance Alone in Newly Diagnosed, Transplant Eligible Patients with Multiple Myeloma (MM): A Randomized Phase 3 Study of the European Myeloma Network (EMN02/HO95 MM Trial)

Pieter Sonneveld, MDPhD, Meral Beksac, Professor, Bronno van der Holt, PhD, Meletios A. Dimopoulos, Angelo Michele Carella, Heinz Ludwig, Christoph Driessen, MD PhD, Ruth Wester, Roman Hajek, Sandra Croockewit, Rossella Troia, Francesca Gay, MD, Anna Maria Cafro, Luca De Rosa, G Fioritoni, MD, Ulf-Henrik Mellqvist, Hans Erik Johnsen, MDDMSc, Sonja Zweegman, MD PhD, Ka Lung Wu, Joana Parreira, MD, Fredrik H. Schjesvold, MD, James D'Rozario, Antonio Palumbo, MD, Michele Cavo
Journal: Blood
Blood (2016) 128 (22): 242.
https://doi.org/10.1182/blood.V128.22.242.242
Published: 2016
Journal Articles

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

Clinical Trials & Observations
Meletios A. Dimopoulos, Antonio Palumbo, Paolo Corradini, Michele Cavo, Michel Delforge, Francesco Di Raimondo, Katja C. Weisel, Albert Oriol, Markus Hansson, Angelo Vacca, María Jesús Blanchard, Hartmut Goldschmidt, Chantal Doyen, Martin Kaiser, Mario Petrini, Pekka Anttila, Anna Maria Cafro, Reinier Raymakers, Jesus San-Miguel, Felipe de Arriba, Stefan Knop, Christoph Röllig, Enrique M. Ocio, Gareth Morgan, Neil Miller, Mathew Simcock, Teresa Peluso, Jennifer Herring, Lars Sternas, Mohamed H. Zaki, Philippe Moreau
Journal: Blood
Blood (2016) 128 (4): 497–503.
https://doi.org/10.1182/blood-2016-02-700872
Published: 2016
Journal Articles

Safety and Efficacy of Pomalidomide Plus Low-Dose Dexamethasone (POM + LoDEX) in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM) in Italy: A Subanalysis of the Stratus Trial (MM-010)

Michele Cavo, Paolo Corradini, Francesco Di Raimondo, Mario Petrini, Anna Maria Cafro, Tommaso Caravita di Toritto, Massimo Offidani, Gianpietro Semenzato, Renato Zambello, Antonio Lazzaro, Maria Teresa Petrucci, Francesco Rodeghiero, Mathew Simcock, Ana Slaughter, Jennifer Herring, Teresa Peluso, Antonio Palumbo
Journal: Blood
Blood (2015) 126 (23): 5376.
https://doi.org/10.1182/blood.V126.23.5376.5376
Published: 2015
Journal Articles

Autologous Transplantation Versus Cyclophosphamide-Lenalidomide-Prednisone Followed By Lenalidomide-Prednisone Versus Lenalidomide Maintenance in Multiple Myeloma: Long-Term Results of a Phase III Trial

Francesca Gay, Valeria Magarotto, MD, Maria Teresa Petrucci, Francesco Di Raimondo, Luděk Pour, Tommaso Caravita, Vlastimil Scudla, Anna Maria Cafro, Anna Marina Liberati, Stefano Spada, Maisnar Vladimir, Norbert Pescosta, Roberto Ria, Massimo Offidani, Sara Bringhen, Annalisa Bernardini, Francesca Patriarca, Paolo Corradini, Roberto Foà, Nicola Cascavilla, Lucio Catalano, Andrew Spencer, Roman Hajek, Mario Boccadoro, MD, Antonio Palumbo
Journal: Blood
Blood (2015) 126 (23): 392.
https://doi.org/10.1182/blood.V126.23.392.392
Published: 2015