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Journal Articles

Late Hematologic Recovery after CPX-351 Induction Chemotherapy in AML: Predictive Disease and Patient's Factors and Their Impact on Survival

Michela Rondoni, Paola Minetto, Bruna Puglisi, Francesco Saraceni, Lorenzo Brunetti, Anna Maria Mianulli, Monica Bocchia, Adele Santoni, Carola Riva, Barbara Giannini, Federica Monaco, Beatrice Zannetti, Claudia Cellini, Annalisa Nicoletti, Anna Maria Valenti, Debora Capelli, Donatella Raspadori, Attilio Olivieri, Francesco Lanza, Claudio Graziano, Patrizia Tosi, Roberto Massimo Lemoli, Fabio Guolo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4275.
https://doi.org/10.1182/blood-2023-182993
Published: 2023
Journal Articles

Carfilzomib-Lenalidomide-Dexamethasone (KRd) Vs. Lenalidomide-Dexamethasone (Rd) in Newly Diagnosed Fit or Intermediate-Fit Multiple Myeloma Patients Not Eligible for Autologous Stem-Cell Transplantation (Phase III EMN20 Trial): Analysis of Sustained Undetectable Minimal Residual Disease (MRD)

Sara Bringhen, Elisabetta Antonioli, Barbara Gamberi, Benedetto Bruno, Daniele Derudas, Patrizia Tosi, Francesca Fazio, Rita Mazza, Sonia Ronconi, Paolo Corradini, Flavia Lotti, Claudia Cellini, Antonietta Pia Falcone, Piero Galieni, Roberto Ria, Angelo Belotti, Donato Mannina, Anna Maria Cafro, Clotilde Cangialosi, Iolanda Donatella Vincelli, Alessandra Lombardo, Alessandra Larocca, Mario Boccadoro, Mattia D'Agostino
Journal: Blood
Blood (2023) 142 (Supplement 1): 205.
https://doi.org/10.1182/blood-2023-177673
Published: 2023
Journal Articles

Bortezomib-Melphalan-Prednisone (VMP) Vs. Lenalidomide-Dexamethasone (Rd) in Transplant-Ineligible Real-Life Multiple Myeloma Patients: Updated Results of the Randomized Phase IV Real MM Trial

Sara Bringhen, Mattia D'Agostino, Nicola Giuliani, Irene Attucci, Renato Zambello, Sonia Ronconi, Iolanda Donatella Vincelli, Alessandro Allegra, Giovanna Leonardi, Giuseppe Rossi, Francesco Cattel, Andrea Capra, Piero Galieni, Alessandra Lombardo, Francesca Bonello, Patrizia Tosi, Maide Maria Cavalli, Elisa Sciorsi, Donato Mannina, Roberto Ria, Francesca Patriarca, Michele Cavo, Silvia Mangiacavalli, Giulia Benevolo, Andrea Evangelista, Mario Boccadoro, Benedetto Bruno, Alessandra Larocca
Journal: Blood
Blood (2022) 140 (Supplement 1): 1814–1816.
https://doi.org/10.1182/blood-2022-162178
Published: 2022
Journal Articles

Total Metabolic Tumor Volume Is Confirmed As Independent Prognostic Factor in Treatment Naïve Follicular Lymphoma Patients and Can be Combined with FLIPI2 to Improve Prognostic Accuracy. a FOLL12 Substudy By the Fondazione Italiana Linfomi

Stefano Luminari, Luca Guerra, Carla Minoia, Stephane Chauvie, Antonella Anastasia, Federica Cavallo, Paolo Corradini, Sara Rattotti, Rexhep Durmo, Chiara Ghiggi, Jacopo Olivieri, Simone Ferrero, Gloria Margiotta Casaluci, Luca Nassi, Caterina Stelitano, Francesca Ricci, Vittorio Ruggero Zilioli, Antonio Pinto, Manuela Zanni, Bolis Silvia, Caterina Patti, Michele Merli, Annalisa Chiarenza, Gerardo Musuraca, Patrizia Tosi, Massimo Federico, Annibale Versari
Journal: Blood
Blood (2022) 140 (Supplement 1): 1313–1315.
https://doi.org/10.1182/blood-2022-166225
Published: 2022
Journal Articles

Efficacy and Safety of Luspatercept in Adult Patients with Transfusion-Dependent Anemia Due to Very Low, Low and Intermediate Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts, Who Had an Unsatisfactory Response to or Are Ineligible for Erythropoietin-Based Therapy: A Retrospective Multicenter Study By Fondazione Italiana Sindromi Mielodisplastiche (FiSiM ETS)

Luca Lanino, Prassede Salutari, Alessandra Perego, Bruno Fattizzo, Marta Riva, Marta Ubezio, Pellegrino Musto, Daniela Cilloni, Esther Natalie Oliva, Maria Teresa Voso, Anna Maria Pelizzari, Antonella Poloni, Isabella Capodanno, Chiara Elena, Claudio Fozza, Fabrizio Pane, Massimo Breccia, Marco De Gobbi, Francesco Di Bassiano, Daniela Barraco, Elena Crisà, Dario Ferrero, Chiara Frairia, Antonella Vaccarino, Davide Griguolo, Stefania Paolini, Martina Quintini, Mariarosaria Sessa, Mauro Turrini, Monica Bocchia, Nicola Di Renzo, Elisa Diral, Cristina Foli, Alfredo Molteni, Ubaldo Occhini, Giulia Rivoli, Carmine Selleri, Roberto Bono, Anna Calvisi, Andrea Castelli, Eros Di Bona, Ambra Di Veroli, Luana Fianchi, Sara Galimberti, Daniele Grimaldi, Monia Marchetti, Marianna Norata, Alessandro Rambaldi, Ilaria Tanasi, Patrizia Tosi, Ilaria Naldi, Valeria Santini, Matteo G. Della Porta
Journal: Blood
Blood (2022) 140 (Supplement 1): 6945–6948.
https://doi.org/10.1182/blood-2022-164559
Published: 2022
Journal Articles

The Accuracy of the International Myeloma Working Group Frailty Score in Capturing Health-Related Quality of Life Profile of Patients with Relapsed Refractory Multiple Myeloma

Fabio Efficace, Gianluca Gaidano, Maria Teresa Petrucci, Pasquale Niscola, Lucia Tognazzi, Elisabetta Antonioli, Francesco Cottone, Ombretta Annibali, Agostino Tafuri, Catello Califano, Alessandra Larocca, Leonardo Potenza, Giulia Palazzo, Claudio Fozza, Domenico Pastore, Gian Matteo Rigolin, Massimo Offidani, Alessandra Romano, Patrizia Tosi, Charalampia Kyriakou, Nicola Cascavilla, Stefano Molica, Alessandro Gozzetti, Daniele Derudas, Marco Vignetti, Michele Cavo
Journal: Blood
Blood (2021) 138 (Supplement 1): 115.
https://doi.org/10.1182/blood-2021-145977
Published: 2021
Journal Articles

Dose/schedule-adjusted Rd-R vs continuous Rd for elderly, intermediate-fit patients with newly diagnosed multiple myeloma

Clinical Trials & Observations
Alessandra Larocca, Francesca Bonello, Gianluca Gaidano, Mattia D’Agostino, Massimo Offidani, Nicola Cascavilla, Andrea Capra, Giulia Benevolo, Patrizia Tosi, Monica Galli, Roberto Marasca, Nicola Giuliani, Annalisa Bernardini, Elisabetta Antonioli, Delia Rota-Scalabrini, Claudia Cellini, Alessandra Pompa, Federico Monaco, Francesca Patriarca, Tommaso Caravita di Toritto, Paolo Corradini, Paola Tacchetti, Mario Boccadoro, Sara Bringhen
Journal: Blood
Blood (2021) 137 (22): 3027–3036.
https://doi.org/10.1182/blood.2020009507
Published: 2021
Includes: Supplemental data
Journal Articles

Azacitidine and Lenalidomide in Higher-Risk Myelodysplastic Syndromes. Long-Term Results of a Randomized Phase II Multicenter Study and Impact of Cytogenetic Scores and Mutational Status on Long-Lasting Responses

Carlo Finelli, Sarah Parisi, MDPhD, Matilde Y Follo, PhD, Cristina Clissa, MD, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Costanza Bosi, MD, Isabella Capodanno, MD, Barbara Castagnari, MD, Anna Candoni, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Giovanna Leonardi, Maurizio Miglino, PhD, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, Andrea Pellagatti, Jacqueline Boultwood, Lucio Cocco, MD, Michele Cavo
Journal: Blood
Blood (2020) 136 (Supplement 1): 45.
https://doi.org/10.1182/blood-2020-138371
Published: 2020
Journal Articles

On-Demand Plerixafor with Cyclophosphamide and G-CSF for Hematopoietic Stem-Cell Mobilization in Multiple Myeloma Patients: Preliminary Results of a Prospective Observational Study (MOZOBL06877)

Roberto Mina, MD, Francesca Bonello, Giuseppe Milone, Maria Teresa Petrucci, Chiara Nozzoli, Velia Bongarzoni, Andrea Capra, Francesco Pisani, Giusy Cetani, Alessandra Malfitano, Delia Rota Scalabrini, Stelvio Ballanti, Roberto M. Lemoli, Patrizia Tosi, Daniele Derudas, Tommaso Caravita di Toritto, Massimo Offidani, Pellegrino Musto, Paolo Corradini, Michele Cavo, Mario Boccadoro, Alessandra Larocca
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-136316
Published: 2020
Journal Articles

Poor Prognosis of Multiple Myeloma Predicted By High Levels of Circulating Plasma Cells Is Independent from Other High-Risk Features but Is Modulated By the Achievement of Minimal Residual Disease Negativity

Luca Bertamini, MD, Mariella Grasso, Mattia D'Agostino, MD, Anna Pascarella, Patrizia Tosi, Federico Monaco, Francesco Pisani, Paola Bertazzoni, Milena Gilestro, Andrea Capra, Piero Galieni, Ombretta Annibali, Vincenzo Pavone, Stefano Molica, MD, Sonia Ronconi, Paola Tacchetti, Pellegrino Musto, Francesca Gay, MD, Mario Boccadoro, Stefania Oliva
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-137075
Published: 2020
Journal Articles

Integrative Analysis of Baseline Prognostic Features and Achievement of Minimal Residual Disease Negativity As Predictors of Early Relapse in Transplant-Eligible Multiple Myeloma Patients

Francesca Gay, MD, Gian Maria Zaccaria, Massimo Offidani, Federico Vozella, Paolo Becco, Angelo Belotti, Andrea Capra, Monica Galli, Fortunato Morabito, Luca Bertamini, Francesco Pisani, Piero Galieni, Rita Rizzi, Alessandro Gozzetti, Norbert Pescosta, Luca De Rosa, Franco Narni, Milena Gilestro, Salvatore Palmieri, Michele Cea, Patrizia Tosi, Nicola Giuliani, Pellegrino Musto, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2019) 134 (Supplement_1): 605.
https://doi.org/10.1182/blood-2019-125588
Published: 2019
Journal Articles

In Systemic Masocytosis, Midostaurin Targets Both Kit and Aurora Kinase a Reverting H3K36Me3 Deficiency and Synergizes with Second-Generation Tyrosine Kinase Inhibitors

Manuela Mancini, PhD, Cecilia Monaldi, Dr, Sara De Santis, Dr, Cristina Papayannidis, Michela Rondoni, MD, Luana Bavaro, Dr, Margherita Martelli, Dr, Antonio Curti, MD PhD, Maria Chiara Fontana, PhD, Samantha Bruno, Dr, Roberta Zanotti, MD, Massimiliano Bonifacio, MD, Luigi Scaffidi, MD, Livio Pagano, MD, Marianna Criscuolo, MD, Francesco Albano, MD, Fabio Ciceri, MD, Chiara Elena, MD, Patrizia Tosi, Massimo Delledonne, Carla Avanzato, Luciano Xumerle, Peter Valent, MD, Giovanni Martinelli, Michele Cavo, Simona Soverini, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4204.
https://doi.org/10.1182/blood-2019-126538
Published: 2019
Journal Articles

Comparison of Two Different Therapeutic Regimens with Azacitidine and Lenalidomide (Combined versus Sequential) in Higher-Risk Myelodysplastic Syndromes. Update of Long-Term Results of a Randomized Phase II Multicenter Study

Carlo Finelli, MD, Cristina Clissa, MD, Matilde Y Follo, PhD, Sarah Parisi, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Isabella Capodanno, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Lucio Cocco, MD, Michele Cavo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2018-99-117714
Published: 2018
Journal Articles

MDM2 and Aurora Kinase a Contribute to SETD2 Loss of Function in Advanced Systemic Mastocytosis: Implications for Pathogenesis and Treatment

Manuela Mancini, PhD, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, MD, Luana Bavaro, Margherita Martelli, Abbenante Maria Chiara, Antonio Curti, Elisa Ficarra, Giulia Paciello, Maria Chiara Fontana, MSc, Roberta Zanotti, MD, Massimiliano Bonifacio, Luigi Scaffidi, MD, Livio Pagano, Marianna Criscuolo, Francesco Albano, MD, Fabio Ciceri, MD, Chiara Elena, MD, Patrizia Tosi, MD, Massimo Delledonne, Carla Avanzato, Luciano Xumerle, Peter Valent, Giovanni Martinelli, MD, Michele Cavo, MD, Simona Soverini, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1779.
https://doi.org/10.1182/blood-2018-99-113278
Published: 2018
Journal Articles

Carfilzomib-Lenalidomide-Dexamethasone (KRd) Induction-Autologous Transplant (ASCT)-Krd Consolidation Vs KRd 12 Cycles Vs Carfilzomib-Cyclophosphamide-Dexamethasone (KCd) Induction-ASCT-KCd Consolidation: Analysis of the Randomized Forte Trial in Newly Diagnosed Multiple Myeloma (NDMM)

Francesca Gay, MD, Chiara Cerrato, MD, Delia Rota Scalabrini, MD, Monica Galli, MD, Angelo Belotti, MD, Elena Zamagni, MD, Antonio Ledda, MD, Mariella Grasso, MD, Emanuele Angelucci, MD, Anna Marina Liberati, MD, Patrizia Tosi, MD, Francesco Pisani, MD, Stefano Spada, Ombretta Annibali, MD, Anna Baraldi, MD, Paola Omedé, Piero Galieni, MD, Rita Rizzi, MD, Norbert Pescosta, MD, Sonia Ronconi, MD, Donatella Vincelli, MD, Anna Maria Cafro, MD, Massimo Offidani, MD, Antonio Palumbo, MD, Pellegrino Musto, MD, Michele Cavo, MD, Mario Boccadoro, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 121.
https://doi.org/10.1182/blood-2018-99-112093
Published: 2018
Journal Articles

Efficacy and Feasibility of Dose/Schedule-Adjusted Rd-R Vs. Continuous Rd in Elderly and Intermediate-Fit Newly Diagnosed Multiple Myeloma (NDMM) Patients: RV-MM-PI-0752 Phase III Randomized Study

Alessandra Larocca, MD, Marco Salvini, MD, Lorenzo De Paoli, MD, Nicola Cascavilla, MD, Giulia Benevolo, MD, Monica Galli, MD, Vittorio Montefusco, MD, Tommaso Caravita di Toritto, MD, Anna Baraldi, MD, Stefano Spada, Nicola Giuliani, MD PhD, Chiara Pautasso, Stefano Pulini, MD, Sonia Ronconi, MD, Norbert Pescosta, MD, Anna Marina Liberati, MD, Francesca Patriarca, MD, Claudia Cellini, MD, Patrizia Tosi, MD, Massimo Offidani, MD, Michele Cavo, MD, Antonio Palumbo, MD, Mario Boccadoro, MD, Sara Bringhen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 305.
https://doi.org/10.1182/blood-2018-99-111796
Published: 2018
Journal Articles

Eltrombopag As Second Line Therapy in Adult Patients with Primary Immune Thrombocytopenia (ITP) in Attempt to Achieve Long-Term Remission. Preliminary Analysis of a Phase II, Multicenter, Prospective Study By Gimema Group (the ESTIT Study)

Elisa Lucchini, MD, Francesca Palandri, PhD MD, Stefano Volpetti, MD, Nicola Vianelli, MD, Giuseppe Auteri, MD, Elena Rossi, MD, Andrea Patriarca, MD, Giuseppe Carli, MD, Wilma Barcellini, MD, Patrizia Tosi, MD, Ugo Consoli, MD, Federica Valeri, MD, Cristina Santoro, MD PhD, Francesca Paoloni, Paola Fazi, MD, Elena Boggio, PhD, Umberto Dianzani, MD PhD, Ilaria Giardini, Monica Carpenedo, Renato Fanin, MD, Francesco Zaja, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1135.
https://doi.org/10.1182/blood-2018-99-113314
Published: 2018
Journal Articles

Health-Related Quality of Life and Symptom Burden in Chronic Myeloid Leukemia Patients Treated with First Line with Imatinib Versus Those Treated with Dasatinib: First Results of the Leonidas Study

Fabio Efficace, PhD, Michele Baccarani, MD, Fabio Stagno, MD PhD, Alessandra Iurlo, MD PhD, Elisabetta Abruzzese, MD PhD, Luigi Scaffidi, Massimo Breccia, MD, PhD, Fausto Castagnetti, MD PhD, Emilio Usala, MD, Monica Crugnola, MD, Isabella Capodanno, Bruno Martino, Mario Tiribelli, MD, Gianluca Gaidano, MD PhD, Alberto Bosi, MD, Luigia Luciano, MD, Patrizia Pregno, Francesco Cottone, Patrizia Tosi, MD, Nicola Cascavilla, MD, Gianni Binotto, Susanne Saussele, MD, Claudio Fozza, Micaela Bergamaschi, MD, Rosaria Sancetta, MD, Giovanni Caocci, MD, Gianantonio Rosti, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3422.
https://doi.org/10.1182/blood.V130.Suppl_1.3422.3422
Published: 2017
Journal Articles

A Randomized Study of Carfilzomib-Lenalidomide-Dexamethasone Vs Carfilzomib-Cyclophosphamide-Dexamethasone Induction in Newly Diagnosed Myeloma Patients Eligible for Transplant: High Efficacy in High- and Standard-Risk Patients

Francesca Maria Gay, Delia Rota Scalabrini, MD, Angelo Belotti, MD, Monica Galli, MD PhD, Elena Zamagni, MD, Massimo Offidani, MD, Stefania Oliva, MD, Vittorio Montefusco, MD, Renato Zambello, MD, Antonio Ledda, MD, Mariella Grasso, MD, Sara Aquino, MD, Fabrizio Esma, Patrizia Tosi, MD, Francesco Pisani, MD, Ombretta Annibali, Anna Marina Liberati, Anna Baraldi, MD, Piero Galieni, MD, Giorgina Specchia, MD, Norbert Pescosta, MD, Katia Mancuso, MD, Laura Paris, MD, Rossella Ribolla, MD, Valentina Coha, MD, Antonio Palumbo, MD, Pellegrino Musto, MD, Michele Cavo, MD, Mario Boccadoro
Journal: Blood
Blood (2017) 130 (Supplement 1): 4541.
https://doi.org/10.1182/blood.V130.Suppl_1.4541.4541
Published: 2017
Journal Articles

Bortezomib-Based Therapy Overcomes the Adverse Impact of Renal Impairment in Transplant Eligible Patients: An Analysis of the Prospective Randomized EMN02/HO95 Study

Meletios A. Dimopoulos, Efstathios Kastritis, Roman Hajek, Luca Dozza, Meral Beksac, MD, Alessandra Larocca, Hans Erik Johnsen, MD Professor, Ulf-Henrik Mellqvist, MD, Anders Waage, MD PhD, Sonja Zweegman, MD PhD, Heinz Ludwig, MD, Lucia Pantani, MD, Andrew Spencer, MD, Anna Pascarella, Marina Martello, Susana Carvalho, Hlif Steingrimsdottir, MD, Claudia Cellini, MD, Petra Cornelisse, Rossella Troia, Patrizia Tosi, MD, Bronno van der Holt, Mario Boccadoro, Pieter Sonneveld, MDPhD, Michele Cavo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4545.
https://doi.org/10.1182/blood.V130.Suppl_1.4545.4545
Published: 2017