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Journal Articles

Acute Promyelocytic Leukemia: Long-Term Outcomes from the HARMONY Project

Maria Teresa Voso, Luca Guarnera, Sören Lehmann, Konstanze Döhner, Hartmut Döhner, Uwe Platzbecker, Nigel H. Russell, Richard James Dillon, Ian Thomas, Gert J Ossenkoppele, Torsten Haferlach, Marco Vignetti, Edoardo La Sala, Alfonso Piciocchi, Paola Fazi, Ángela Villaverde Ramiro, Laura Tur Giménez, Carmelo Gurnari, Lars Bullinger, Jesus M. Hernandez
Journal: Blood
Blood blood.2024026186.
https://doi.org/10.1182/blood.2024026186
Published: 2024
Includes: Supplemental data
Journal Articles

Factors Predicting Short-Term Symptom Burden in Patients with Aggressive B-Cell Lymphomas Treated with CAR T-Cell Therapy: A Real-World Study By the Gimema

Fabio Efficace, Francesca Bonifazi, Pier Luigi Zinzani, Ilaria Cutini, Annalisa Chiappella, Barbara Botto, Maria Chiara Tisi, Stefania Bramanti, Thomas Baldi, Francesca Tartaglia, Mirko Farina, Simone Ragaini, Massimiliano Gambella, Enrico Orciuolo, Massimo Martino, Maurizio Martelli, Claudio Cartoni, Paolo Corradini, Paola Fazi, Marco Vignetti, Alice Di Rocco
Journal: Blood
Blood (2024) 144 (Supplement 1): 7823.
https://doi.org/10.1182/blood-2024-199498
Published: 2024
Journal Articles

Identification of Genomic Structural Variants (SVs) with Adverse Prognostic Significance in Normal-Karyotype (nk) Acute Myeloid Leukemia (AML) Patients

Niccolò Bartalucci, Francesco Mannelli, Danilo Tarantino, Barbara Scappini, Alessio Enderti, Giacomo Gianfaldoni, Matteo Piccini, Simone Romagnoli, Daniele Colazzo, Leonardo Signori, Fiorenza Irushani, Silvia Salmoiraghi, Tiziana Ottone, Alfonso Piciocchi, Margherita Vannucchi, Maria Chiara Siciliano, Roberto Boccacci, Silvia Orsi, Alessia Civini, Paola Fazi, Raffaella Santi, Marco Vignetti, Stefania Bortoluzzi, Alberto Bosi, Adriano Venditti, Alessandro Rambaldi, Maria Teresa Voso, Paola Guglielmelli, Alessandro M. Vannucchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 65.
https://doi.org/10.1182/blood-2024-198342
Published: 2024
Journal Articles

Molecular Outcome of Chronic Myeloid Leukemia Affected Patients Not in Deep Molecular Response: The “Others” from the Gimema Labnet Network

Fabio Stagno, Rosalba Cucci, Giovanni Marsili, Fausto Castagnetti, Sara Galimberti, Barbara Izzo, Federica Sorà, Simona Soverini, Monica Messina, Alfonso Piciocchi, Massimiliano Bonifacio, Daniela Cilloni, Alessandra Iurlo, Giovanni Martinelli, Gianantonio Rosti, Paola Fazi, Marco Vignetti, Massimo Breccia, Alessandro Allegra, Fabrizio Pane
Journal: Blood
Blood (2024) 144 (Supplement 1): 992.
https://doi.org/10.1182/blood-2024-210201
Published: 2024
Journal Articles

Digital Twins As Control Groups to Accelerate Assessment of Safety and Efficacy of Novel Treatment Strategies in Ph-Negative Acute Lymphoblastic Leukemia

Alfonso Piciocchi, Monica Messina, Giovanni Marsili, Marta Cipriani, Francesca Paola Paoloni, Davide Lazzarotto, Anna Candoni, Alessandro Rambaldi, Matteo Leoncin, Paola Fazi, Marco Vignetti, Robin Foà, Sabina Chiaretti
Journal: Blood
Blood (2024) 144 (Supplement 1): 274.
https://doi.org/10.1182/blood-2024-200643
Published: 2024
Journal Articles

Profiling Baseline Health-Related Quality of Life of Patients with Newly Diagnosed Myeloid Malignancies: A Pooled Analysis of 3349 Patients with AML, APL and MDS from the International Proactive Project

Fabio Efficace, Adriano Venditti, Thomas Baldi, Joanna Canham, Giovanni Martinelli, Alfonso Piciocchi, Mike Dennis, Steve Knapper, Nigel H. Russell, Sean Johnson, Maria Teresa Voso, Marco Vignetti, Ian Thomas
Journal: Blood
Blood (2024) 144 (Supplement 1): 407.
https://doi.org/10.1182/blood-2024-204588
Published: 2024
Journal Articles

The Prognostic Value for Survival of Self-Reported Fatigue in Patients with Newly Diagnosed Myelodysplastic Syndromes: An International Prospective Observational Study By the Gimema

Fabio Efficace, Wael Al Essa, Uwe Platzbecker, Pasquale Niscola, Giuseppe A Palumbo, Giovanni Caocci, Serena Puglia, Francesco Sparano, Massimo Breccia, Mario Luppi, Reinhard Stauder, Alessandra Ricco, Duska Petranovic, Frederic Baron, Maria Teresa Voso, Chiara Frairia, Isabella Capodanno, Chiara Sarlo, Rosangela Invernizzi, Claudio Fozza, Maribel Doro, Marco Vignetti
Journal: Blood
Blood (2024) 144 (Supplement 1): 404.
https://doi.org/10.1182/blood-2024-204633
Published: 2024
Journal Articles

Centralized MRD Assessment in Gimema AML1718 Trial, a Phase 2 Open-Label Study of Venetoclax Combined with Intensified FLAI Chemotherapy (V-FLAI) As Induction Therapy of Non Low-Risk AML

Paola Minetto, Fabio Guolo, Sara Rosellini, Alfonso Piciocchi, Giovanni Marconi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Giovanni Marsili, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Valentina Arena, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Elisabetta Tedone, Giovanni Martinelli, Roberto Massimo Lemoli
Journal: Blood
Blood (2024) 144 (Supplement 1): 1574.
https://doi.org/10.1182/blood-2024-198139
Published: 2024
Journal Articles

Survival Analysis of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Saveria Capria, Michela Rondoni, Matteo Giovanni Della Porta, Germana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Anna Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 2891.
https://doi.org/10.1182/blood-2024-207842
Published: 2024
Journal Articles

Evaluating the Impact of Cross-over from Imatinib to Nilotinib on the Overall Survival in Chronic Myeloid Leukemia Using Inverse Probability of Censoring Weighting: Results from the Gimema Sustrenim Study

Alfonso Piciocchi, Giovanni Marsili, Ylenia Belperio, Monica Messina, Francesca Paola Paoloni, Stefano Soddu, Isabella Capodanno, Rosaria Sancetta, Elisabetta Abruzzese, Alessandro Pulsoni, Monia Lunghi, Giovanni Caocci, Fausto Castagnetti, Paola Fazi, Marco Vignetti, Massimo Breccia, Fabrizio Pane
Journal: Blood
Blood (2024) 144 (Supplement 1): 4530.
https://doi.org/10.1182/blood-2024-198366
Published: 2024
Journal Articles

Decitabine in older patients with AML: quality of life results of the EORTC-GIMEMA-GMDS-SG randomized phase 3 trial

Clinical Trials & Observations
Fabio Efficace, Michal Kicinski, Corneel Coens, Stefan Suciu, Walter J. F. M. van der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F. M. Posthuma, Anna Candoni, Frédéric Baron, Olivier Legrand, Andrea Mengarelli, Paola Fazi, Marco Vignetti, Anne Giraut, Pierre W. Wijermans, Gerwin Huls, Michael Lübbert
Journal: Blood
Blood (2024) 144 (5): 541–551.
https://doi.org/10.1182/blood.2023023625
Published: 2024
Includes: Supplemental data
Journal Articles

Association of Financial Toxicity and Health-Related Quality of Life in Long-Term Survivors of Acute Promyelocytic Leukemia Treated within a Universal Healthcare System

Francesco Sparano, Adriano Venditti, Maria Teresa Voso, Johannes M. Giesinger, Alberto Brini, Paola Fazi, Marco Vignetti, Fabio Efficace
Journal: Blood
Blood (2023) 142 (Supplement 1): 3804.
https://doi.org/10.1182/blood-2023-179741
Published: 2023
Journal Articles

A Propensity Score Weighting Analysis Emphasizes the Progress of the Gimema Approach in Adult Ph-Positive Acute Lymphoblastic Leukemia in the TKI Era

Alfonso Piciocchi, Sabina Chiaretti, Marta Cipriani, Monica Messina, Loredana Elia, Irene Della Starza, Antonella Vitale, Paola Fazi, Marco Vignetti, Robin Foa
Journal: Blood
Blood (2023) 142 (Supplement 1): 4200.
https://doi.org/10.1182/blood-2023-179102
Published: 2023
Journal Articles

36-Month Follow-up Results of the Gimema ‘Veritas’ Trial of Front-Line Venetoclax and Rituximab (VenR) in Young and Fit Patients with Chronic Lymphocytic Leukemia and an Adverse Biologic Profile

Francesca Romana Mauro, Irene Della Starza, Monica Messina, Gianluigi Reda, Livio Trentin, Marta Coscia, Paolo Sportoletti, Lorella Orsucci, Valentina Arena, Gianluca Gaidano, Roberto Marasca, Roberta Murru, Luca Laurenti, Caterina Stelitano, Donato Mannina, Fiorella Ilariucci, Massimo Massaia, Gian Matteo Rigolin, Lydia Scarfo, Monia Marchetti, Luciano Levato, Monica Tani, Annalisa Arcari, Gerardo Musuraca, Marina Deodato, Piero Galieni, Valeria Belsito Patrizi, Daniela Gottardi, Anna Marina Liberati, Annamaria Giordano, Maria Chiara Molinari, Sara Pepe, Costanza Andriola, Veronica Mattiello, Andrea Visentin, Candida Vitale, Francesco Albano, Antonino Neri, Maria Stefania De Propris, Mauro Nanni, Ilaria Del Giudice, Anna Guarini, Paola Fazi, Marco Vignetti, Alfonso Piciocchi, Antonio Cuneo, Robin Foà
Journal: Blood
Blood (2023) 142 (Supplement 1): 1905.
https://doi.org/10.1182/blood-2023-181597
Published: 2023
Journal Articles

Final Analysis for the Primary End-Point of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Capria Saveria, Michela Rondoni, Matteo Giovanni Della Porta, Geramana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1536.
https://doi.org/10.1182/blood-2023-184678
Published: 2023
Journal Articles

Selected Genomic Structural Variants Refine ELN-Based Prognostic Stratification of Patients with Acute Myeloid Leukemia and Normal Karyotype

Niccolò Bartalucci, Francesco Mannelli, Simone Romagnoli, Danilo Tarantino, Barbara Scappini, Alessio Enderti, Giacomo Gianfaldoni, Fiorenza Irushani, Matteo Piccini, Silvia Salmoiraghi, Tiziana Ottone, Alfonso Piciocchi, Silvia Orsi, Marco Vignetti, Alessia Civini, Chiara Pavoni, Renato Bassan, Stefania Bortoluzzi, Adriano Venditti, Alessandro Rambaldi, Maria Teresa Voso, Paola Guglielmelli, Alessandro Maria Vannucchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4317.
https://doi.org/10.1182/blood-2023-178599
Published: 2023
Journal Articles

Lifestyle Behaviors and Health-Related Quality of Life in Long-Term Survivors of Acute Myeloid Leukemia: An International Survivorship Study By the Gimema, EORTC Quality of Life and Leukemia Groups

Fabio Efficace, Laura Cannella, Xavier Thomas, Meltem Kurt Yuksel, Silvia Maria Trisolini, Capria Saveria, Alberto Brini, Ernesta Audisio, Luca Maurillo, Roberto Massimo Lemoli, Annalisa Imovilli, Irina Panovska Stavridis, Martina Quattrone, Maria Ciccone, Nunzio Filardi, Nicola Fracchiolla, Daniele Vallisa, Monica Crugnola, Lorella Maria Antonia Melillo, Matevz Skerget, Marco Vignetti, Frederic Baron
Journal: Blood
Blood (2023) 142 (Supplement 1): 3801.
https://doi.org/10.1182/blood-2023-179248
Published: 2023
Journal Articles

Long-Term Outcome of 1296 Patients with Newly Diagnosed with APL: A Harmony Alliance Study

Luca Guarnera, Soren Lehmann, Konstanze Döhner, Hartmut Döhner, Uwe Platzbecker, Nigel H. Russell, Richard Dillon, Ian Thomas, Gert Ossenkoppele, Marco Vignetti, Edoardo la Sala, Alfonso Piciocchi, Angela Villaverde Ramiro, Laura Tur, Carmelo Gurnari, Lars Bullinger, Jesús María Hernández-Rivas, Maria Teresa Voso
Journal: Blood
Blood (2023) 142 (Supplement 1): 727.
https://doi.org/10.1182/blood-2023-185121
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

Impact-AML: A European Master Framework for Cohort Studies and Pragmatic Clinical Trials in Relapse or Refractory Acute Myeloid Leukemia

Giovanni Marconi, Petros Kountouris, Jiri Mayer, Lars Bullinger, Dirk Reinhardt, Pau Montesinos, Pietro Merli, Marco Vignetti, Jos Dumortier, Jesús María Hernández-Rivas, Michael Heuser, Rolandas Gerbutavicius, Antonio Francesco Maturo, Gianni D'Errico, Samantha Nier, Chiara Zingaretti, Irene Azzali, Federica Campacci, Maria Del Mar Mañú-Pereira, Franco Locatelli, Rüdiger Hehlmann, Dietger W. Niederwieser, Giovanni Martinelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1533.
https://doi.org/10.1182/blood-2023-184745
Published: 2023