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Journal Articles

Venetoclax and decitabine in myeloproliferative neoplasm-blast Phase (MPN-BP): Results of enable, a gimema and airc-mynerva multicenter, Phase 2 trial

Free
Alessandro Vannucchi, Francesco Mannelli, Francesca Crupi, Jessica Caroprese, Mirko Lomi, Alessio Enderti, Stefano Soddu, Alfonso Piciocchi, Alessandro Rambaldi, Giovanni Caocci, Monica Bocchia, Ernesta Audisio, Antonio Curti, Fabrizio Pane, Erika Borlenghi, Massimo Breccia, Niccolò Bartalucci, Marco Frigeni, Olga Mulas, Corrado Zuanelli Brambilla, Chiara Frairia, Cristina Papayannidis, Francesco Grimaldi, Lorenzo Masina, Monica Rondi, Marco Sanna, Pellegrino Musto, Prassede Salutari, Patrizia Chiusolo, Elisa Coviello, Mario Luppi, Daniela Cilloni, leonardo Signori, Luca Malcovati, Maria Paola Martelli, Matteo Della Porta, Rossella Manfredini, Maria Teresa Voso, Paola Fazi, Marco Vignetti, Paola Guglielmelli
Journal: Blood
Blood (2025) 146 (Supplement 1): 1025.
https://doi.org/10.1182/blood-2025-1025
Published: 2025
Journal Articles

CPX-351 is a feasible bridge to allogeneic hematopoietic stem cell transplantation in TP53 mutated acute myeloid leukemia with  myelodisplastic related changes or therapy related without del(17p): Sub-analysis from a large italian real world retrospective study

Free
Elisabetta Todisco, Ivana Lotesoriere, Federico Lussana, Valentina Mancini, Federica Gigli, Cristina Papayannidis, Michela Rondoni, Felicetto Ferrara, Sara Mastaglio, Annalina Piccioni, Michelina Dargenio, Andrea Corbingi, Francesco Mannelli, Alessandro Cignetti, Patrizia Zappasodi, Maria Paola Martelli, Monia Lunghi, Luana Fianchi, Patrizia Chiusolo, Francesco Grimaldi, Federica Pilo, Carla Fili, Debora Capelli, Massimo Breccia, Monica Bocchia, Monica Fumagalli, Sara Galimberti, Luca Maurillo, Calogero Vetro, Alessandra Sperotto, Caterina Patti, Erika Borlenghi, Federica Lessi, Alessandro Isidori, Raffaele Palmieri, Caterina Alati, Samuele Gatani, Chiara Pessina, Paola Minetto, Carola Riva, Marco Frigeni, Nicola Stefano Fracchiolla, Carla Mazzone, Marco Cerrano, Massimo Bernardi, Michele Gottardi, Roberto Cairoli, Adriano Venditti, Livio Pagano, Roberto Lemoli, Fabio Guolo
Journal: Blood
Blood (2025) 146 (Supplement 1): 4608.
https://doi.org/10.1182/blood-2025-4608
Published: 2025
Journal Articles

First interim analysis of venetoclax real-world observational study on newly-diagnosed AML patients in Italy (VERO): Focus on patient and diseases characteristics and quality of life at baseline

Free
Ivana Lotesoriere, Caterina Alati, lorenzo celona, Monia Lunghi, gianluca martini, jacopo nanni, Vincenzo Federico, Antonino Mule', MARINA PARISI, PRASSEDE SALUTARI, Ida Carmosino, Valeria Cardinali, ANDREA PASQUINI, Marco Frigeni, Roberto Cairoli, FEDERICO MORETTI, Anna Candoni, SELENIA VITIELLO, Irene Zacheo, Benedetta Neri, PAOLA FINSINGER, LUIGI DI CAPRIO, GIULIANA GUALBERTI, LUDOVICA MAGI, CARMEN STEFANINI, Marta Ubezio
Journal: Blood
Blood (2025) 146 (Supplement 1): 5159.
https://doi.org/10.1182/blood-2025-5159
Published: 2025
Journal Articles

Elderly Acute Myeloid Leukemia (AML) with NPM1 or FLT3-ITD mutated: Is venetoclax the game changer also in fit patients? a real-life retrospective analysis by the rete ematologica lombarda

Free
Erika Borlenghi, Chiara Cattaneo, Marco Frigeni, Patrizia Zappasodi, Ivana Lotesoriere, Claudia Maria Basilico, Nicola Stefano Fracchiolla, Marta Riva, Massimo Bernardi, Alfredo Molteni, Monica Fumagalli, Paola Maria Cozzi, Federica Gigli, Federico Lussana, Mauro Turrini, Lorenzo Masina, Gianluca Martini, Mariarita Sciumè, Valentina Mancini, Lorenzo Rizzo, Chiara Pagani, Alessandra Tucci, Giuseppe Rossi, Roberto Cairoli, Elisabetta Todisco
Journal: Blood
Blood (2025) 146 (Supplement 1): 3438.
https://doi.org/10.1182/blood-2025-3438
Published: 2025
Journal Articles

Treatment initiation pattern, ramp-up measures and management of AML patients treated in real life in Italy with venetoclax+azacitidine - first interim analysis of the prospective vero study

Free
Marta Ubezio, Caterina Alati, lorenzo celona, Monia Lunghi, gianluca martini, Antonio Curti, Vincenzo Federico, Antonino Mule', MARINA PARISI, PRASSEDE SALUTARI, Massimo Breccia, Valeria Cardinali, Marco Frigeni, matteo piccini, Mariarita Sciumè, DEBORA CAPELLI, Rossella Stella, AMBRA DI VEROLI, CARMINE SELLERI, PAOLA FINSINGER, LUIGI DI CAPRIO, Benedetta Neri, DARIA NUCCIARELLI, VIRGINIA SALA, SILVIA SCHIFANO, Elisabetta Todisco
Journal: Blood
Blood (2025) 146 (Supplement 1): 3383.
https://doi.org/10.1182/blood-2025-3383
Published: 2025
Journal Articles

Health-related quality of life and symptom burden of patients with vexas: Real-world data from a multicenter observational study

Free
Fabio Efficace, Elisa Diral, Daniela Krepper, Corrado Campochiaro, Fabrizio Pane, Giorgia Battipaglia, Erika Morsia, Jacqueline Ferrari, Marco Frigeni, Isabella Capodanno, Gabriele Todisco, Cinzia Sissa, Bruno Fattizzo, Cristina Papayannidis, Paola Guglielmelli, Chiara Cattaneo, Elena Crisa, Arianna Savi, Alfonso Fiumarella, Davide Firinu, Francesca Tartaglia, Laura Cicconi, Antonio Pierini, Paola Triggianese, Paola Fazi, Maria Teresa Voso, Carmelo Gurnari
Journal: Blood
Blood (2025) 146 (Supplement 1): 2685.
https://doi.org/10.1182/blood-2025-2685
Published: 2025
Journal Articles

A novel multi-target NGS application for molecular monitoring of measurable residual disease in Acute Myeloid Leukemia

Free
Annalisa Condorelli, Chiara Pavoni, Federico Lussana, Anna Grassi, Marco Frigeni, Orietta Spinelli, Alessandra Algarotti, Alessandro Rambaldi, Silvia Salmoiraghi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3513.
https://doi.org/10.1182/blood-2025-3513
Published: 2025
Journal Articles

Centralized MRD Assessment in Gimema AML1718 Trial, a Phase 2 Open-Label Study of Venetoclax Combined with Intensified FLAI Chemotherapy (V-FLAI) As Induction Therapy of Non Low-Risk AML

Free
Paola Minetto, Fabio Guolo, Sara Rosellini, Alfonso Piciocchi, Giovanni Marconi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Giovanni Marsili, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Valentina Arena, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Elisabetta Tedone, Giovanni Martinelli, Roberto Massimo Lemoli
Journal: Blood
Blood (2024) 144 (Supplement 1): 1574.
https://doi.org/10.1182/blood-2024-198139
Published: 2024
Journal Articles

Optimizing Acute Myeloid Leukemia Monitoring: A Novel Multi-Target NGS Application for Measurable Residual Disease Assessment

Free
Annalisa Condorelli, Orietta Spinelli, Roberta Stavola, Slawomir Kubik, Yuanlong Liu, Jonathan Bieler, Marco Frigeni, Federico Lussana, Alessandro Rambaldi, Silvia Salmoiraghi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6169.
https://doi.org/10.1182/blood-2024-205645
Published: 2024
Journal Articles

Survival Analysis of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Free
Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Saveria Capria, Michela Rondoni, Matteo Giovanni Della Porta, Germana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Anna Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 2891.
https://doi.org/10.1182/blood-2024-207842
Published: 2024
Journal Articles

Venetoclax and Hypomethylating Agents Confirmed to be Standard Therapy in De Novo and ELN17 Not Adverse Acute Myeloid Leukemia Patients, Unfit for Chemotherapy According to SIE/Sies/GITMO Criteria. a Multicentric Real-Life Study on 379 Patients, By the Hematological Network Rete Ematologica Lombarda (REL)

Free
Erika Borlenghi, Lorenzo Masina, Marco Frigeni, Patrizia Zappasodi, Ivana Lotesoriere, Claudia Basilico, Nicola Fracchiolla, Massimo Bernardi, Marta Riva, Alfredo Molteni, Monica Fumagalli, Mauro Turrini, Paola Maria Cozzi, Federica Gigli, Chiara Cattaneo, Federico Lussana, Chiara Pagani, Valentina Mancini, Mariarita Sciumè, Gianluca Martini, Alessandro Bruno, Lorenzo Rizzo, Alessandra Tucci, Giuseppe Rossi, Roberto Cairoli, Elisabetta Todisco
Journal: Blood
Blood (2024) 144 (Supplement 1): 2863.
https://doi.org/10.1182/blood-2024-202530
Published: 2024
Journal Articles

CPX-351 Induces High Rate of Complete Remission in the New ICC/ELN 2022 Adverse-Risk Entity ‘AML with MDS-Related Gene Mutations’: Evidence from a Large Real-World Italian Study

Free
Gaetano Cimino, Matteo Caridi, Valeria Cardinali, Sofia Sciabolacci, Luana Fianchi, Federico Lussana, Sara Mastaglio, Monica Fumagalli, Sara Galimberti, Luca Maurillo, Federica Gigli, Caterina Patti, Erika Borlenghi, Monia Lunghi, Samuele Gatani, Jr., Ivana Lotesoriere, Marco Frigeni, Nicola Stefano Fracchiolla, Patrizia Chiusolo, Roberta La Starza, Caterina Matteucci, Massimo Bernardi, Antonio Pierini, Alessandra Carotti, Roberto Cairoli, Livio Pagano, Roberto Massimo Lemoli, Maria Teresa Voso, Adriano Venditti, Fabio Guolo, Elisabetta Todisco, Maria Paola Martelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 2849.
https://doi.org/10.1182/blood-2024-210042
Published: 2024
Journal Articles

Methodology and Clinical Significance of Longitudinal UBA1 Clonal Burden Evaluation in Vexas Syndrome

Free
Carmelo Gurnari, Elisa Galossi, Eleonora Lumia, Alfonso Piciocchi, Mariadomenica Divona, Tiziana Ottone, Elisa Casciani, Francesca Romano, Elisa Diral, Alessandro Tomelleri, Federico Caroni, Antonio Vitale, Gregorio Maria Bergonzi, Annalisa Condorelli, Giorgia Battipaglia, Erika Morsia, Antonella Poloni, Elena Crisa, Daniela Caravelli, Paola Triggianese, Arianna Savi, Chiara Cardamone, Matteo Dragani, Giulia Rivoli, Federica Pilo, Davide Firinu, Sara Plebani, Francesco D'Agostino, Alessandro D'Ambrosio, Katja Sockel, Antonio Curti, Cristina Papayannidis, Marco Frigeni, Attilio Olivieri, Fabrizio Pane, Monica Bocchia, Luca Cantarini, Alessandro Rambaldi, Corrado Campochiaro, Lorenzo Dagna, Raffaella Greco, Fabio Ciceri, Orietta Spinelli, Christian Thiede, Maria Teresa Voso
Journal: Blood
Blood (2024) 144 (Supplement 1): 2690.
https://doi.org/10.1182/blood-2024-194413
Published: 2024
Journal Articles

Real World Outcome of Unfit Patients with Acute Myeloid Leukemia Treated with the Combination Venetoclax Plus Hypomethylating Agents in the Gimema AML2320 Observational Trial

Free
Adriano Venditti, Alfonso Piciocchi, Stefano Soddu, Marco Frigeni, Raffaele Palmieri, Erika Borlenghi, Nicola Fracchiolla, Maria Paola Martelli, Ernesta Audisio, Giacomo Gianfaldoni, Calogero Vetro, Nicola di Rienzo, Daniela Esposito, Ambra Di Veroli, Carmine Selleri, Federica Gigli, Antonio Curti, Antonino Mulè, Catello Califano, Sara Bigliardi, Massimo Breccia, Claudio Fozza, Monica Bocchia, Albana Lico, Federico Simonetti, Elisabetta Pierdomenico, Francesco Buccisano, Maria Ilaria Del Principe, Luca Maurillo, Paola Fazi, Marco Vignetti, Felicetto Ferrara, Roberto Cairoli, Giuseppe Rossi, Alessandro Rambaldi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1514.
https://doi.org/10.1182/blood-2023-178505
Published: 2023
Journal Articles

IPSS-M for Transplant Decision Making of Patients with Myelodysplastic Syndromes: A Retrospective Single-Center Study

Free
Annalisa Condorelli, Silvia Salmoiraghi, Chiara Pavoni, Matteo Raviglione, Alessia Civini, Alessandro Putelli, Marco Frigeni, Tamara Intermesoli, Federico Lussana, Giulia Quaresmini, Marta Bellini, Maria Chiara Finazzi, Orietta Spinelli, Alessandro Rambaldi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6449.
https://doi.org/10.1182/blood-2023-187369
Published: 2023
Journal Articles

Improving Prediction of Early Death in Acute Promyelocytic Leukemia: External Validation Study from Italian Single Center Experience

Free
Marco Frigeni, Leonardo Gerosa, Chiara Pavoni, Tamara Intermesoli, Giulia Quaresmini, Marta Bellini, Marta Castelli, Clara Belotti, Martina Milani, Silvia Salmoiraghi, Orietta Spinelli, Fabio Lorenzano, Alessandro Putelli, Monica Galli, Federico Lussana, Alessandro Rambaldi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4232.
https://doi.org/10.1182/blood-2023-187507
Published: 2023
Journal Articles

SIE/Sies/GITMO Criteria in Elderly Patients with Acute Myeloid Leukemia (AML): Useful Also in the New Drug Era? a Multicentric Real-Life Study By the Hematological Network Rete Ematologica Lombarda (REL)

Free
Erika Borlenghi, Lorenzo Masina, Marco Frigeni, Ivana Lotesoriere, Alfredo Molteni, Monica Fumagalli, Marta Riva, Patrizia Zappasodi, Massimo Bernardi, Nicola Fracchiolla, Federica Gigli, Claudia Basilico, Chiara Pagani, Federico Lussana, Paola Perfetti, Chiara Cattaneo, Monica Tajana, Silvia Viola, Gianluca Martini, Gloria Catalano, Mariarita Sciumè, Annalisa Condorelli, Giselda Cela, Giuseppe Rossi, Alessandra Tucci, Roberto Cairoli, Elisabetta Todisco
Journal: Blood
Blood (2023) 142 (Supplement 1): 956.
https://doi.org/10.1182/blood-2023-180568
Published: 2023
Journal Articles

Final Analysis for the Primary End-Point of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Free
Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Capria Saveria, Michela Rondoni, Matteo Giovanni Della Porta, Geramana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1536.
https://doi.org/10.1182/blood-2023-184678
Published: 2023
Journal Articles

The Impact of Baseline Genetic Profile and Treatment on Hematological Toxicity in CEBPA -Mutated Acute Myeloid Leukemia

Free
Francesco Mannelli, Matteo Piccini, Marco Frigeni, Giacomo Gianfaldoni, Sara Bencini, Silvia Salmoiraghi, Barbara Scappini, Benedetta Peruzzi, Roberto Caporale, Gaia Ciolli, Laura Fasano, Francesca Crupi, Elisa Quinti, Andrea Pasquini, Sofia Pilerci, Fiorenza Vanderwert, Giada Rotunno, Fabiana Pancani, Leonardo Signori, Danilo Tarantino, Chiara Maccari, Vivian Paradiso, Francesco Annunziato, Orietta Spinelli, Paola Guglielmelli, Alessandro Rambaldi, Alessandro Maria Vannucchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4215.
https://doi.org/10.1182/blood-2023-184845
Published: 2023
Journal Articles

Centralized MRD Assessment at Early Timepoints in Gimema AML1718 Trial, a Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk AML

Free
Paola Minetto, Fabio Guolo, Sara Rosellini, Alfonso Piciocchi, Giovanni Marconi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Francesca Paola Paoloni, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Valentina Arena, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Elisabetta Tedone, Giovanni Martinelli, Roberto M. Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1567.
https://doi.org/10.1182/blood-2023-189777
Published: 2023