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Carmelo Gurnari
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Journal Articles

Acute Promyelocytic Leukemia: Long-Term Outcomes from the HARMONY Project

Maria Teresa Voso, Luca Guarnera, Sören Lehmann, Konstanze Döhner, Hartmut Döhner, Uwe Platzbecker, Nigel H. Russell, Richard James Dillon, Ian Thomas, Gert J Ossenkoppele, Torsten Haferlach, Marco Vignetti, Edoardo La Sala, Alfonso Piciocchi, Paola Fazi, Ángela Villaverde Ramiro, Laura Tur Giménez, Carmelo Gurnari, Lars Bullinger, Jesus M. Hernandez
Journal: Blood
Blood blood.2024026186.
https://doi.org/10.1182/blood.2024026186
Published: 2024
Includes: Supplemental data
Journal Articles

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Simona Pagliuca, Carmelo Gurnari, Arda Durmaz, Ashwin Kishtagari, Zain Virk, Lukasz P. Gondek, Matthew Guo, Maria Bettinotti, Mark B Juckett, Qing Cao, Suresh Kumar Balasubramanian, Vikram Dhillon, Ben K. Tomlinson, Koen van Besien, Alice Aarnink, Marie Thérèse Rubio, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 927.
https://doi.org/10.1182/blood-2024-210565
Published: 2024
Journal Articles

Artificial-Intelligence, Data-Driven, Comprehensive Classification of Myeloid Neoplasms Based on Genomic, Morphological and Histological Features

Luca Lanino, Saverio D'Amico, Giulia Maggioni, Najla H. Al Ali, Yu-Hung Wang, Carmelo Gurnari, Nico Gagelmann, Jan Philipp Bewersdorf, Somedeb Ball, Paola Guglielmelli, Manja Meggendorfer, Anthony M. Hunter, Anne Sophie Kubasch, Erica Travaglino, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Cristina Astrid Tentori, Alessandro Buizza, Elisabetta Sauta, Matteo Zampini, Elena Riva, Gianluca Asti, Mattia Delleani, Francesca Ficara, Armando Santoro, Claudia Sala, Daniele Dall'Olio, Lorenzo Dall'Olio, Tariq Kewan, Ilaria Carola Casetti, Hussein Awada, Blanca Xicoy, Vladan Vucinic, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Angela Consagra, David Sallman, Wolfgang Kern, Massimo Bernardi, Patrizia Chiusolo, Lorenza Maria Borin, Maria Teresa Voso, Lisa Pleyer, Laura Palomo, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Guillermo Garcia-Manero, Sanam Loghavi, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Nicolaus Kröger, Pierre Fenaux, Michaela Fontenay, Valeria Santini, Torsten Haferlach, Ulrich Germing, Eric Padron, Marie Robin, Francesco Passamonti, Eric Solary, Alessandro M. Vannucchi, Gastone Castellani, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1005.
https://doi.org/10.1182/blood-2024-204826
Published: 2024
Journal Articles

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Benjamin Kroger, Roni Tamari, Carmelo Gurnari, Julio Alvarenga Thiebaud, Alejandro Marinos Velarde, Yazan F Madanat, Robert H. Collins, Clayton Jackson, Vivian Irizarry Gatell, Valeria Visconte, Jaroslaw Maciejewski, David Sallman, Stephen Chung
Journal: Blood
Blood (2024) 144 (Supplement 1): 777.
https://doi.org/10.1182/blood-2024-212380
Published: 2024
Journal Articles

Luspatercept for the Treatment of Transfusion-Dependent Anemia in Patients with Myelodysplastic Neoplasms with del5q, Refractory/Resistant/Intolerant to Prior Treatments (QOL-ONE Phoenix)

Esther Natalie Oliva, Antonella Poloni, Chiara Frairia, Marta Riva, Isabella Capodanno, Ilaria Maria Delfino, Maria Grazia D'Errigo, Corrado Mammì, Giuseppe Ianni', Gina Zini, Davide Griguolo, Monia Marchetti, Carmelo Gurnari, Maria Teresa Voso, Bruno Fattizzo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6741.
https://doi.org/10.1182/blood-2024-205325
Published: 2024
Journal Articles

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Arda Durmaz, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Luca Guarnera, Serhan Unlu, Hussein Awada, Praveena Thiagarajan, Yuriy Fedorov, Drew Adams, Carmelo Gurnari, Jacob G. Scott, Jaroslaw Maciejewski, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2024-208903
Published: 2024
Journal Articles

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Serhan Unlu, Christopher Haddad, Tariq Kewan, Olisaemeka Ogbue, Arda Durmaz, Waled Bahaj, Arooj Ahmed, Carlos Bravo-Perez, Luca Guarnera, Hetty E. Carraway, Yasuo Kubota, Carmelo Gurnari, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 3199.
https://doi.org/10.1182/blood-2024-205865
Published: 2024
Journal Articles

Aplastic Anemia in the Elderly: Treatment Patterns and Outcomes from an International Observational Study

Bruno Fattizzo, Carmelo Gurnari, Sabrina Giammarco, Antony Ricchiuti, Hussein Awada, Marta Bortolotti, Giacinto Luca Pedone, Francesco Versino, Dario Consonni, Roochi Trikha, Shreyans Gandhi, Simona Sica, Jaroslaw Maciejewski, Austin G. Kulasekararaj, Wilma Barcellini
Journal: Blood
Blood (2024) 144 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2024-198321
Published: 2024
Journal Articles

Personalized Transplant Decision Making for Myelofibrosis in the Era of Molecular Genetics and JAK Inhibition

Nico Gagelmann, Barbara Mora, Filippo Branzanti, Alessandro Maria Vannucchi, Massimo Breccia, Giuseppe Alberto Maria Palumbo, Massimiliano Bonifacio, Erika Morsia, Elena Maria Elli, Mario Tiribelli, Giulia Benevolo, Mirko Farina, Fabrizio Pane, Roberto Massimo Lemoli, Giovanni Caocci, Alessia Tieghi, Gianni Binotto, Francesco Cavazzini, Bruno Martino, Alessandro Isidori, Margherita Maffioli, Elisa Rumi, Tiziano Barbui, Francisco Cervantes, Matteo Giovanni Della Porta, Andrew T. Kuykendall, Marianna Caramella, Alessandra Iurlo, Valerio De Stefano, Jean-Jacques Kiladjian, David Ross, Jason Gotlib, Timothy Devos, Marco Ruggeri, Richard T. Silver, Rachel B. Salit, Thomas Schroeder, Carmelo Gurnari, Simona Pagliuca, Christina Rautenberg, Marie Robin, Marie-Thérèse Rubio, Jaroslaw Maciejewski, Alessandro Rambaldi, Maria Chiara Finazzi, Andrea Bacigalupo, Patrizia Chiusolo, Hans Christian Reinhardt, Bart L. Scott, Nicolaus Kröger, Francesco Passamonti, Francesca Palandri
Journal: Blood
Blood (2024) 144 (Supplement 1): 245.
https://doi.org/10.1182/blood-2024-210804
Published: 2024
Journal Articles

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Olisaemeka Ogbue, Ahmad Kiwan, Hussein Awada, Hetty E. Carraway, Suresh Kumar Balasubramanian, Taha Bat, Yazan F Madanat, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 850.
https://doi.org/10.1182/blood-2024-207770
Published: 2024
Journal Articles

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Ahmad Kiwan, Tariq Kewan, Carlos Bravo-Perez, Valeria Visconte, Carmelo Gurnari, Arda Durmaz, Alexa Siddon, Stephanie Halene, Tarsheen Sethi, Jaroslaw Maciejewski, Francine M. Foss
Journal: Blood
Blood (2024) 144 (Supplement 1): 4436.
https://doi.org/10.1182/blood-2024-209344
Published: 2024
Journal Articles

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Zachary Brady, Luca Guarnera, Matteo D'Addona, Carmelo Gurnari, Chao-Yie Yang, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4096.
https://doi.org/10.1182/blood-2024-208366
Published: 2024
Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Luca Guarnera, Adam Wahida, Carmelo Gurnari, Stephan Hutter, Sabine Stainczyk, Nakisha D Williams, Arda Durmaz, Yasuo Kubota, Carlos Bravo-Perez, Naomi Kawashima, Simona Pagliuca, Yimin Huang, Thomas Laframboise, Valeria Visconte, Wencke Walter, Manja Meggendorfer, Claudia Haferlach, Wolfgang Kern, Frank Westermann, Lars Feuerbach, Torsten Haferlach, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4104.
https://doi.org/10.1182/blood-2024-209923
Published: 2024
Journal Articles

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Zachary Brady, Nakisha D Williams, Arda Durmaz, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Heesun J. Rogers, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 2675.
https://doi.org/10.1182/blood-2024-208405
Published: 2024
Journal Articles

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

Hussein Awada, Arda Durmaz, Luca Guarnera, Tyler Birkholz, Olisaemeka Ogbue, Mark Orland, Olga Lytvynova, Matteo D'Addona, Praveena Thiagarajan, Arooj Ahmed, Zachary Brady, Carlos Bravo-Perez, Valeria Visconte, Jaroslaw Maciejewski, Carmelo Gurnari
Journal: Blood
Blood (2024) 144 (Supplement 1): 4085.
https://doi.org/10.1182/blood-2024-211518
Published: 2024
Journal Articles

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Aashray Mandala, Carlos Bravo-Perez, Matteo D'Addona, Zachary Brady, Mark Orland, Luca Guarnera, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Arooj Ahmed, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4084.
https://doi.org/10.1182/blood-2024-210304
Published: 2024
Journal Articles

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Matteo D'Addona, Eno-Obong B. Udoh, Luca Guarnera, Carlos Bravo-Perez, Serhan Unlu, Zachary Brady, Kartik Lakhotiya, Hussein Awada, Christopher Haddad, Aashray Mandala, Mark Orland, Arda Durmaz, Carmelo Gurnari, Aaron D. Viny, Jaroslaw Maciejewski, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 6696.
https://doi.org/10.1182/blood-2024-207614
Published: 2024
Journal Articles

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

Carlos Bravo-Perez, Carmelo Gurnari, Arda Durmaz, Stephan Hutter, Zachary Brady, Hussein Awada, Aashray Mandala, Luca Guarnera, Matteo D'Addona, Kartik Lakhotiya, Praveena Thiagarajan, Alan Eli Lichtin, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 31.
https://doi.org/10.1182/blood-2024-208885
Published: 2024
Journal Articles

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Kartik Lakhotiya, Carmelo Gurnari, Carlos Bravo-Perez, Aashray Mandala, Matteo D'Addona, Christopher Haddad, Mark Orland, Zachary Brady, Luca Guarnera, Praveena Thiagarajan, Ishani Nautiyal, Simona Pagliuca, Hari Krishnamurthy, Karthik Krishna, Vasanth Jayaraman, Valeria Visconte, Jaroslaw Maciejewski, Arda Durmaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 35.
https://doi.org/10.1182/blood-2024-210990
Published: 2024
Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1003.
https://doi.org/10.1182/blood-2024-200104
Published: 2024