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Journal Articles

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Simona Pagliuca, Carmelo Gurnari, Arda Durmaz, Ashwin Kishtagari, Zain Virk, Lukasz P. Gondek, Matthew Guo, Maria Bettinotti, Mark B Juckett, Qing Cao, Suresh Kumar Balasubramanian, Vikram Dhillon, Ben K. Tomlinson, Koen van Besien, Alice Aarnink, Marie Thérèse Rubio, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 927.

https://doi.org/10.1182/blood-2024-210565

Published: 2024

Journal Articles

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Benjamin Kroger, Roni Tamari, Carmelo Gurnari, Julio Alvarenga Thiebaud, Alejandro Marinos Velarde, Yazan F Madanat, Robert H. Collins, Clayton Jackson, Vivian Irizarry Gatell, Valeria Visconte, Jaroslaw Maciejewski, David Sallman, Stephen Chung

Blood (2024) 144 (Supplement 1): 777.

https://doi.org/10.1182/blood-2024-212380

Published: 2024

Journal Articles

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Arda Durmaz, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Luca Guarnera, Serhan Unlu, Hussein Awada, Praveena Thiagarajan, Yuriy Fedorov, Drew Adams, Carmelo Gurnari, Jacob G. Scott, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 4980.

https://doi.org/10.1182/blood-2024-208903

Published: 2024

Journal Articles

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Serhan Unlu, Christopher Haddad, Tariq Kewan, Olisaemeka Ogbue, Arda Durmaz, Waled Bahaj, Arooj Ahmed, Carlos Bravo-Perez, Luca Guarnera, Hetty E. Carraway, Yasuo Kubota, Carmelo Gurnari, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 3199.

https://doi.org/10.1182/blood-2024-205865

Published: 2024

Journal Articles

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Olisaemeka Ogbue, Ahmad Kiwan, Hussein Awada, Hetty E. Carraway, Suresh Kumar Balasubramanian, Taha Bat, Yazan F Madanat, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 850.

https://doi.org/10.1182/blood-2024-207770

Published: 2024

Journal Articles

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Ahmad Kiwan, Tariq Kewan, Carlos Bravo-Perez, Valeria Visconte, Carmelo Gurnari, Arda Durmaz, Alexa Siddon, Stephanie Halene, Tarsheen Sethi, Jaroslaw Maciejewski, Francine M. Foss

Blood (2024) 144 (Supplement 1): 4436.

https://doi.org/10.1182/blood-2024-209344

Published: 2024

Journal Articles

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Zachary Brady, Luca Guarnera, Matteo D'Addona, Carmelo Gurnari, Chao-Yie Yang, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4096.

https://doi.org/10.1182/blood-2024-208366

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Zachary Brady, Nakisha D Williams, Arda Durmaz, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Heesun J. Rogers, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Valeria Visconte

Blood (2024) 144 (Supplement 1): 2675.

https://doi.org/10.1182/blood-2024-208405

Published: 2024

Journal Articles

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

Hussein Awada, Arda Durmaz, Luca Guarnera, Tyler Birkholz, Olisaemeka Ogbue, Mark Orland, Olga Lytvynova, Matteo D'Addona, Praveena Thiagarajan, Arooj Ahmed, Zachary Brady, Carlos Bravo-Perez, Valeria Visconte, Jaroslaw Maciejewski, Carmelo Gurnari

Blood (2024) 144 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2024-211518

Published: 2024

Journal Articles

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Aashray Mandala, Carlos Bravo-Perez, Matteo D'Addona, Zachary Brady, Mark Orland, Luca Guarnera, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Arooj Ahmed, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4084.

https://doi.org/10.1182/blood-2024-210304

Published: 2024

Journal Articles

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Matteo D'Addona, Eno-Obong B. Udoh, Luca Guarnera, Carlos Bravo-Perez, Serhan Unlu, Zachary Brady, Kartik Lakhotiya, Hussein Awada, Christopher Haddad, Aashray Mandala, Mark Orland, Arda Durmaz, Carmelo Gurnari, Aaron D. Viny, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 6696.

https://doi.org/10.1182/blood-2024-207614

Published: 2024

Journal Articles

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

Carlos Bravo-Perez, Carmelo Gurnari, Arda Durmaz, Stephan Hutter, Zachary Brady, Hussein Awada, Aashray Mandala, Luca Guarnera, Matteo D'Addona, Kartik Lakhotiya, Praveena Thiagarajan, Alan Eli Lichtin, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 31.

https://doi.org/10.1182/blood-2024-208885

Published: 2024

Journal Articles

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Kartik Lakhotiya, Carmelo Gurnari, Carlos Bravo-Perez, Aashray Mandala, Matteo D'Addona, Christopher Haddad, Mark Orland, Zachary Brady, Luca Guarnera, Praveena Thiagarajan, Ishani Nautiyal, Simona Pagliuca, Hari Krishnamurthy, Karthik Krishna, Vasanth Jayaraman, Valeria Visconte, Jaroslaw Maciejewski, Arda Durmaz

Blood (2024) 144 (Supplement 1): 35.

https://doi.org/10.1182/blood-2024-210990

Published: 2024

Journal Articles

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

Blood (2024) 144 (Supplement 1): 5634.

https://doi.org/10.1182/blood-2024-209240

Published: 2024

Journal Articles

A Real-Life Experience of Iptacopan in Paroxysmal Nocturnal Hemoglobinuria

Arooj Ahmed, Mark Orland, Praveena Thiagarajan, Megan Basch, Serhan Unlu, Carlos Bravo-Perez, Hussein Awada, Arda Durmaz, Carmelo Gurnari, Olga Lytvynova, Zachary Brady, Matteo D'Addona, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 5695.

https://doi.org/10.1182/blood-2024-211788

Published: 2024

Journal Articles

LGL Versus MGUS: Clonal Immune Pathogenetic Culprits in Hyporegenerative Anemias and Red Cell Aplasia

Carlos Bravo-Perez, Carmelo Gurnari, Zachary Brady, Arooj Ahmed, Matteo D'Addona, Luca Guarnera, Aashray Mandala, Christopher Haddad, Kartik Lakhotiya, Praveena Thiagarajan, Megan Nakashima, Hetty E. Carraway, Heesun J. Rogers, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 5234.

https://doi.org/10.1182/blood-2024-209314

Published: 2024

Journal Articles

Targeting Poly(U) Binding Splicing Factor 60 (PUF60): A Small-Molecule Inhibitor Shows Anti-Leukemic Activity and Impacts Cell Cycle in Leukemia Models

Xinrui Yuan, Mona Kazemi Sabzvar, Amol D Patil, Arda Durmaz, Jaroslaw Maciejewski, Valeria Visconte, Chao-Yie Yang

Blood (2024) 144 (Supplement 1): 7470.

https://doi.org/10.1182/blood-2024-210241

Published: 2024

Journal Articles

Genetic Profiling and Survival Analysis of Patients with Acute Myeloid Leukemia and a History of Autoimmune Disease

Blood (2024) 144 (Supplement 1): 6127.

https://doi.org/10.1182/blood-2024-199358

Published: 2024

Journal Articles

Elucidating the Somatic Genetic Rescue Underlying Del(20q) Myeloid Neoplasms

Mark Orland, Arda Durmaz, Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Christopher Haddad, Kartik Lakhotiya, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4573.

https://doi.org/10.1182/blood-2024-208520

Published: 2024

NARROW

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

A Real-Life Experience of Iptacopan in Paroxysmal Nocturnal Hemoglobinuria

LGL Versus MGUS: Clonal Immune Pathogenetic Culprits in Hyporegenerative Anemias and Red Cell Aplasia

Targeting Poly(U) Binding Splicing Factor 60 (PUF60): A Small-Molecule Inhibitor Shows Anti-Leukemic Activity and Impacts Cell Cycle in Leukemia Models

Genetic Profiling and Survival Analysis of Patients with Acute Myeloid Leukemia and a History of Autoimmune Disease

Elucidating the Somatic Genetic Rescue Underlying Del(20q) Myeloid Neoplasms

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American Society of Hematology

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ASH Publications

American Society of Hematology

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