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Journal Articles

Genetic Profiling and Survival Analysis of Patients with Acute Myeloid Leukemia and a History of Autoimmune Disease

Blood (2024) 144 (Supplement 1): 6127.

https://doi.org/10.1182/blood-2024-199358

Published: 2024

Journal Articles

Budd-Chiari Syndrome: Pathogenetic Factors and Completeness of Screening for Paroxysmal Nocturnal Hemoglobinuria

Aashray Mandala, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Arda Durmaz, Mark Orland, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 1254.

https://doi.org/10.1182/blood-2024-211609

Published: 2024

Journal Articles

Using Machine Learning to Predict the Risk of Evolution to Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia

Erika Ren, Katayoun Elizabeth Khalilian, Mutlu Mete, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Taha Bat

Blood (2024) 144 (Supplement 1): 1315.

https://doi.org/10.1182/blood-2024-203826

Published: 2024

Journal Articles

A Real-Life Experience of Iptacopan in Paroxysmal Nocturnal Hemoglobinuria

Arooj Ahmed, Mark Orland, Praveena Thiagarajan, Megan Basch, Serhan Unlu, Carlos Bravo-Perez, Hussein Awada, Arda Durmaz, Carmelo Gurnari, Olga Lytvynova, Zachary Brady, Matteo D'Addona, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 5695.

https://doi.org/10.1182/blood-2024-211788

Published: 2024

Journal Articles

Clinical Significance of HOX and Meis gene Expression Profiling in Acute Myeloid Leukemia

Vikram Dhillon, Jeff Aguilar, Paul Kim, Dakshin Padmanabhan, Sandhya Dhiman, Gregory Dyson, Jaroslaw Maciejewski, Suresh Kumar Balasubramanian

Blood (2024) 144 (Supplement 1): 6162.

https://doi.org/10.1182/blood-2024-212337

Published: 2024

Journal Articles

LGL Versus MGUS: Clonal Immune Pathogenetic Culprits in Hyporegenerative Anemias and Red Cell Aplasia

Carlos Bravo-Perez, Carmelo Gurnari, Zachary Brady, Arooj Ahmed, Matteo D'Addona, Luca Guarnera, Aashray Mandala, Christopher Haddad, Kartik Lakhotiya, Praveena Thiagarajan, Megan Nakashima, Hetty E. Carraway, Heesun J. Rogers, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 5234.

https://doi.org/10.1182/blood-2024-209314

Published: 2024

Journal Articles

Targeting Poly(U) Binding Splicing Factor 60 (PUF60): A Small-Molecule Inhibitor Shows Anti-Leukemic Activity and Impacts Cell Cycle in Leukemia Models

Xinrui Yuan, Mona Kazemi Sabzvar, Amol D Patil, Arda Durmaz, Jaroslaw Maciejewski, Valeria Visconte, Chao-Yie Yang

Blood (2024) 144 (Supplement 1): 7470.

https://doi.org/10.1182/blood-2024-210241

Published: 2024

Journal Articles

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Jill Durkin, Daniel Vail, Dongxu Jiang, Yahan Zhang, Simon Schlanger, Jaroslaw Maciejewski, Thomas Laframboise, Babal K. Jha

Blood (2024) 144 (Supplement 1): 5727.

https://doi.org/10.1182/blood-2024-207943

Published: 2024

Journal Articles

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

Blood (2024) 144 (Supplement 1): 5634.

https://doi.org/10.1182/blood-2024-209240

Published: 2024

Journal Articles

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Matteo D'Addona, Eno-Obong B. Udoh, Luca Guarnera, Carlos Bravo-Perez, Serhan Unlu, Zachary Brady, Kartik Lakhotiya, Hussein Awada, Christopher Haddad, Aashray Mandala, Mark Orland, Arda Durmaz, Carmelo Gurnari, Aaron D. Viny, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 6696.

https://doi.org/10.1182/blood-2024-207614

Published: 2024

Journal Articles

Clonal Evolution of TP53 Configurations with Treatment Predict Prognosis in Myeloid Neoplasms

Dakshin Padmanabhan, Jeff Aguilar, Paul Kim, Sandhya Dhiman, Asmita Shukla, Vikram Dhillon, Sushmitha Nanja Reddy, David Carr, Jay Yang, Julie Boerner, Jaroslaw Maciejewski, Suresh Kumar Balasubramanian

Blood (2024) 144 (Supplement 1): 1540.

https://doi.org/10.1182/blood-2024-210037

Published: 2024

Journal Articles

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Arda Durmaz, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Luca Guarnera, Serhan Unlu, Hussein Awada, Praveena Thiagarajan, Yuriy Fedorov, Drew Adams, Carmelo Gurnari, Jacob G. Scott, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 4980.

https://doi.org/10.1182/blood-2024-208903

Published: 2024

Journal Articles

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Serhan Unlu, Christopher Haddad, Tariq Kewan, Olisaemeka Ogbue, Arda Durmaz, Waled Bahaj, Arooj Ahmed, Carlos Bravo-Perez, Luca Guarnera, Hetty E. Carraway, Yasuo Kubota, Carmelo Gurnari, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 3199.

https://doi.org/10.1182/blood-2024-205865

Published: 2024

Journal Articles

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Ahmad Kiwan, Tariq Kewan, Carlos Bravo-Perez, Valeria Visconte, Carmelo Gurnari, Arda Durmaz, Alexa Siddon, Stephanie Halene, Tarsheen Sethi, Jaroslaw Maciejewski, Francine M. Foss

Blood (2024) 144 (Supplement 1): 4436.

https://doi.org/10.1182/blood-2024-209344

Published: 2024

Journal Articles

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Dongxu Jiang, Daniel J Vail, Yahan Zhang, Raziullah Khan, Anand Tiwari, Simon Schlanger, Kunho Chung, Cassandra Gilmour, Xiaorong Gu, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2664.

https://doi.org/10.1182/blood-2024-211363

Published: 2024

Journal Articles

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Zachary Brady, Luca Guarnera, Matteo D'Addona, Carmelo Gurnari, Chao-Yie Yang, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4096.

https://doi.org/10.1182/blood-2024-208366

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Zachary Brady, Nakisha D Williams, Arda Durmaz, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Heesun J. Rogers, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Valeria Visconte

Blood (2024) 144 (Supplement 1): 2675.

https://doi.org/10.1182/blood-2024-208405

Published: 2024

Journal Articles

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

Hussein Awada, Arda Durmaz, Luca Guarnera, Tyler Birkholz, Olisaemeka Ogbue, Mark Orland, Olga Lytvynova, Matteo D'Addona, Praveena Thiagarajan, Arooj Ahmed, Zachary Brady, Carlos Bravo-Perez, Valeria Visconte, Jaroslaw Maciejewski, Carmelo Gurnari

Blood (2024) 144 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2024-211518

Published: 2024

Journal Articles

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Aashray Mandala, Carlos Bravo-Perez, Matteo D'Addona, Zachary Brady, Mark Orland, Luca Guarnera, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Arooj Ahmed, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4084.

https://doi.org/10.1182/blood-2024-210304

Published: 2024

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Genetic Profiling and Survival Analysis of Patients with Acute Myeloid Leukemia and a History of Autoimmune Disease

Budd-Chiari Syndrome: Pathogenetic Factors and Completeness of Screening for Paroxysmal Nocturnal Hemoglobinuria

Using Machine Learning to Predict the Risk of Evolution to Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia

A Real-Life Experience of Iptacopan in Paroxysmal Nocturnal Hemoglobinuria

Clinical Significance of HOX and Meis gene Expression Profiling in Acute Myeloid Leukemia

LGL Versus MGUS: Clonal Immune Pathogenetic Culprits in Hyporegenerative Anemias and Red Cell Aplasia

Targeting Poly(U) Binding Splicing Factor 60 (PUF60): A Small-Molecule Inhibitor Shows Anti-Leukemic Activity and Impacts Cell Cycle in Leukemia Models

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Clonal Evolution of TP53 Configurations with Treatment Predict Prognosis in Myeloid Neoplasms

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

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American Society of Hematology

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