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Daniel Wiseman
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Journal Articles

Prospera (ABNL-MARRO 002): A randomized phase 2 study of pacritinib vs. hydroxyurea in patients with advanced proliferative chronic myelomonocytic leukemia (CMML)

Free
Zhuoer Xie, Qianxing Mo, Sarah Buckley, David Sallman, Jeffrey Lancet, Michael Savona, Rami Komrokji, Mrinal Patnaik, Daniel Wiseman, Eric Padron
Journal: Blood
Blood (2025) 146 (Supplement 1): 3873.
https://doi.org/10.1182/blood-2025-3873
Published: 2025
Journal Articles

Refining the prognostic hierarchy of TP53 multihit alterations and isolated deletion of chromosome 5q in myelodysplastic syndromes

Free
Maria Julia Montoro, Pamela Acha, Claudia Haferlach, Onyee Chan, Raja Prince-Eladnani, Yasuo Kubota, Felicitas Schulz, Robert Briski, Najla Al Ali, Blanca Xicoy, Laura Palomo, Felix Lopez, Francesc Bosch Albareda, Manja Meggendorfer, Lea Naomi Eder, Andres Jerez, Yu-Hung Wang, Alessia Campagna, Beate Betz, Valeria Santini, Teresa Bernal Del Castillo, Esperanza Such, Anne Sophie Kubasch, Tariq Kewan, Carmelo Gurnari, Carla Zindel, Austin Kulasekararaj, Maria Teresa Voso, Mikkael Sekeres, Nicolas Diaz Varela, Aref Al-Kali, Antonella Pollini, Elisa Diral, Mara Memoli, Uwe Platzbecker, Detlef Haase, Amer Zeidan, Pierre Fenaux, Maria Diez-Campelo, Guillermo Garcia-Manero, Daniel Wiseman, Matteo Della Porta, Ulrich Germing, Jaroslaw Maciejewski, Rami Komrokji, Francesc Sole, Torsten Haferlach, David Valcarcel
Journal: Blood
Blood (2025) 146 (Supplement 1): 2068.
https://doi.org/10.1182/blood-2025-2068
Published: 2025
Journal Articles

SRSF2 mutation-induced CHD8 exon skipping represents a novel pathogenic mediator and therapeutic dependence in chronic myelomonocytic leukemia (CMML)

Free
Yu-Hung Wang, Kristian Gurashi, Laura Guest, Roberto Paredes, Carlos Rivera, Luciano Nicosia, Shalini Sankar, David Walter, Curtis Hart, Sylvie Lachmann, Wei-Hsiang Lin, Antony Adamson, Kiran Batta, Daniel Wiseman
Journal: Blood
Blood (2025) 146 (Supplement 1): 676.
https://doi.org/10.1182/blood-2025-676
Published: 2025
Journal Articles

ASTX727 delivers superior response rates and associated survival benefit versus hydroxycarbamide/best supportive care in CMML and other MDS/MPN overlap syndromes: First results from the Phase 2 UK multicenter randomized ammo trial

Free
Daniel Wiseman, Jak Laight, Rebecca Boucher, Chhaya Sankhalpara, Rebecca Record, Jennifer Byrne, Onima Chowdhury, Dominic Culligan, Nicholas Cunningham, Srinivasan Narayanan, Rob Sellar, Kiran Batta, Manoj Raghavan, Dr. Emma Searle, Catherine Cargo, Steve Knapper, Austin Kulasekararaj
Journal: Blood
Blood (2025) 146 (Supplement 1): 488.
https://doi.org/10.1182/blood-2025-488
Published: 2025
Journal Articles

Patient experience sub-study of a randomised UK multicentre Phase 2 trial of ASTX727 versus hydroxycarbamide/best supportive care in myelodysplastic (MDS)/myeloproliferative (MPN) overlap syndromes (AMMO)

Free
Ashleigh Ward, Sally Taylor, Grant Punnett, Ramsay Devaraj, Chhaya Sankhalpara, Rebecca Record, Kiran Batta, Jennifer Byrne, Catherine Cargo, Onima Chowdhury, Dominic Culligan, Nicholas Cunningham, Steve Knapper, Austin Kulasekararaj, Srinivasan Narayanan, Manoj Raghavan, Rob Sellar, Daniel Wiseman, Janelle Yorke
Journal: Blood
Blood (2025) 146 (Supplement 1): 8164.
https://doi.org/10.1182/blood-2025-8164
Published: 2025
Journal Articles

Myelodysplastic/myeloproliferative overlap neoplasms: Clinicopathological features, treatment strategies, and outcomes — a UK multicentre cohort Study

Free
Ahmad Alabdulkarim, Michael Luong, Yu-Hung Wang, Elena Torre, Athanasia Papadaki, Adrian Choy, Vaishak Vidyadhar, Jeyanthy Bavanthan, Alex Rampotas, Nomathamsanqa Tshuma, Delphine Appadurai, Kamini Hari, Alasdair Longden, Noha Gasmelseed, Annabel Mcmillan, Samah Alimam, Andrew Wilson, Jenny O'Nions, Kavita Raj, Rob Sellar, Marc Mansour, Rajeev Gupta, Jonathan Lambert, Daniel Wiseman, Elspeth Payne, Donal McLornan
Journal: Blood
Blood (2025) 146 (Supplement 1): 7365.
https://doi.org/10.1182/blood-2025-7365
Published: 2025
Journal Articles

Investigating the clonal and biological underpinnings of systemic mastocytosis with an associated hematological neoplasm

Free
Nana Adjoa Ben-Crentsil, Somedeb Ball, Hannah Newman, Christopher Ryder, Surendra Neupane, Anthony Hunter, Yu-Hung Wang, Kiran Batta, Kristian Gurashi, Traci Kruer, Maria Balasis, Ariel Quintana, Rami Komrokji, David Sallman, Andrew Kuykendall, Tracy George, Daniel Wiseman, Eric Padron
Journal: Blood
Blood (2025) 146 (Supplement 1): 3763.
https://doi.org/10.1182/blood-2025-3763
Published: 2025
Journal Articles

Redefining the myeloid disease continuum: Machine learning–based development and validation of an integrated multimodal classification of myeloid neoplasms

Free
Yu-Hung Wang, Kristian Gurashi, Chien-Chin Lin, Carmelo Gurnari, Hussein Awada, Adrian Mosquera, Manuel Perez Encinas, Donal McLornan, Andrius Zucenka, Talha Badar, Bor-Sheng Ko, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Nick Telford, Kiran Batta, Daniel Wiseman
Journal: Blood
Blood (2025) 146 (Supplement 1): 4347.
https://doi.org/10.1182/blood-2025-4347
Published: 2025
Journal Articles

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms

Free
Justin Taylor, Xiaoli Mi, Khrystyna North, Moritz Binder, Alexander Penson, Terra Lasho, Katherine Knorr, Michael Haddadin, Bo Liu, Joseph Pangallo, Salima Benbarche, Daniel Wiseman, Ayalew Tefferi, Stephanie Halene, Yang Liang, Mrinal M. Patnaik, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2020) 136 (13): 1477–1486.
https://doi.org/10.1182/blood.2020006868
Published: 2020
Includes: Supplemental data
Journal Articles

Post Allograft Rituximab Responsive Cytopenia (RRC)

Free
Samar Kulkarni, MD, John Murray, RGN, MSc, David Kaye, MSc, Michael Dennis, FRCPath, Anna Castleton, FRCPath, Mohd K Mamat, MRCP, James Cavet, Daniel Wiseman, FRCPath, Tim Somervaille, FRCPath, Sven Sommerfeld, MRCP, Richard Chasty, FRCPath, Adrian Bloor, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5645.
https://doi.org/10.1182/blood-2019-132214
Published: 2019
Journal Articles

The SF3B1 K700E Mutation Induces R-Loop Accumulation and Associated DNA Damage

Free
Shalini Singh, Doaa Ahmed, Hamid Dolatshad, Dharamveer Tatwavedi, Ulrike Schulze, Andrea Sanchi, Sarah Ryley, Ashish Dhir, Lee Carpenter, Suzanne M. Watt, Amal M. Abdel-Aal, Sohair K. Sayed, Somia A. Mohamed, Anna Schuh, PhD, Nicholas J. Proudfoot, Andriana G. Kotini, Eirini P. Papapetrou, Daniel Wiseman, FRCPath, Andrea Pellagatti, Jacqueline Boultwood
Journal: Blood
Blood (2019) 134 (Supplement_1): 4219.
https://doi.org/10.1182/blood-2019-126981
Published: 2019
Journal Articles

Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study

Free
Steven Knapper, DM, Michael Dennis, MD, MRCP, FRCPath, Mark W Drummond, PhDMD, Robert K. Hills, MA, DPhil, MSc, Richard James Dillon, MA, PhD MRCP, FRCPath, Christopher Pocock, MD PhD, Dominic J. Culligan, Paresh Vyas, Daniel Wiseman, MB, ChB, Joanna Zabkiewicz, PhD, Marie Hodges, PhD MSc, Catherine Cargo, MB, FRCPath, Jan Taylor, PhD MSc, BSc, Laura Upton, Melissa Wright, David Bowen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1818.
https://doi.org/10.1182/blood-2018-99-110356
Published: 2018
Journal Articles

Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis

Free
Akihide Yoshimi, Kuan-Ting Lin, PhD, Daniel Wiseman, MB, ChB, Andrew M Intlekofer, MD PhD, Bo Wang, Alessandro Pastore, MD, Mohammad Rahman, Stanley Chun-Wei Lee, PhD, Bo Liu, PhD, Jean-Baptiste Micol, MD PhD, Stephane De Botton, Virginie Penard-Lacronique, PhD, Alan H. Shih, MD PhD, Eytan M. Stein, MD, Benjamin H Durham, MD BS, Daichi Inoue, MD PhD, Xiao Jing Zhang, Todd Albrecht, Young Rock Chung, MS, Shouyong Peng, Silvia Buonamici, PhD, James Palacino, PhD, Peter Smith, PhD, Craig B. Thompson, MD, Ross L. Levine, MD, Eric Wagner, PhD, Adrian R. Krainer, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 473.
https://doi.org/10.1182/blood.V130.Suppl_1.473.473
Published: 2017
Journal Articles

Transcriptome of DNA Repair Genes in CMML: Rationale for Targeting ERCC1 and CDKN1A As a Synthetic Lethality Approach

Free
Ana M Hurtado, Ginés Luengo-Gil, Tzu Hua Chen-Liang, Fabio Amaral, Laura Palomo, MSc, Eva Lumbreras, Bartlomiej Przychodzen, Eva Caparrós, Maria Luz Amigo, Maria Díez-Campelo, Lurdes Zamora, PhD, Eduardo José Salido, MD, Jaroslaw P. Maciejewski, PhD MD FACP, Francisco José Ortuño, Vicente Vicente, Consuelo Del Cañizo, MDPhD, Francesc Sole, PhD, Francisca Ferrer Marin, Daniel Wiseman, MB, ChB, Andres Jerez
Journal: Blood
Blood (2017) 130 (Supplement 1): 1679.
https://doi.org/10.1182/blood.V130.Suppl_1.1679.1679
Published: 2017
Journal Articles

Retrospective Analysis of Seasonal Respiratory Viral Infections (SRVI) in Hematology, Lymphoma and Oncology Patients

Free
Samar Kulkarni, MD MRCP, FRCPath, Stephanie Michail, MBBS, Charlotte Smith, MSc, Joanna Tomlins, MSc, John Murray, BSc (hons), MSc, Michael Dennis, FRCPath, Jim Cavet, FRCPath, Tim Somervaille, MD PhD, Daniel Wiseman, FRCPath, Anna Z Castleton, FRCPath, Adrian Bloor
Journal: Blood
Blood (2016) 128 (22): 4608.
https://doi.org/10.1182/blood.V128.22.4608.4608
Published: 2016
Journal Articles

Higher Incidence and Risk of Developing Second Solid Cancers (SSC) after Haematopoetic Stem Cell Transplantation (HSCT) As Compared to General Population

Free
Samar Kulkarni, MD MRCP, FRCPath, John Murray, BSc (hons), MSc, Charlotte Smith, MSc, Stephanie Cleaver, RGN, Michael Dennis, FRCPath, Jim Cavet, FRCPath, Tim Somervaille, MD PhD, Anna Z Castleton, FRCPath, Daniel Wiseman, FRCPath, Joanna Tomlins, MSc, Kaz Mamat, MRCP, Angie Leather, MSc, Rita Angelica, BSc, Adrian Bloor
Journal: Blood
Blood (2016) 128 (22): 4610.
https://doi.org/10.1182/blood.V128.22.4610.4610
Published: 2016
Journal Articles

Therapeutic Cyclosporine Exposure Measured As Area Under the Curve (AUC) Significantly Influences the Outcome after Allogeneic Hematopoetic Stem Cell Transplant (alloHSCT)

Free
Samar Kulkarni, MD MRCP, FRCPath, John Murray, BSc (hons), MSc, Michael Dennis, FRCPath, Jim Cavet, FRCPath, Anna Z Castleton, FRCPath, Tim Somervaille, MDPhD, Daniel Wiseman, FRCPath, Joanna Tomlins, MSc, Adrian Bloor
Journal: Blood
Blood (2016) 128 (22): 2237.
https://doi.org/10.1182/blood.V128.22.2237.2237
Published: 2016
Journal Articles

Pre-Transplantation Assessment Of Mortality (PAM) Score Is a Poor Predictor For Survival In The Highest Risk Group When Used In T Cell Depleted Myeloablative Allogeneic Transplants

Free
Bhuvan Kishore, Daniel Wiseman, MBChB, MRCP, Emmanouil Nikolousis, Richard Lovell, Donald Milligan, MD, Kathy Holder, Lynn Bratby, Vidhya Murthy, Shankaranarayana Paneesha
Journal: Blood
Blood (2013) 122 (21): 5553.
https://doi.org/10.1182/blood.V122.21.5553.5553
Published: 2013
Journal Articles

Distal Limb Infiltration by Transformed Lymphoplasmacytoid Lymphoma.

Free
James Cavet, MRCPath, PhD, Daniel Wiseman, MBChB
Journal: Blood
Blood (2006) 108 (11): 4647.
https://doi.org/10.1182/blood.V108.11.4647.4647
Published: 2006