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Journal Articles

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

Blood (2022) 140 (13): 1496–1506.

https://doi.org/10.1182/blood.2022016985

Published: 2022

Includes: Supplemental data

Journal Articles

Novel somatic mutations in UBA1 as a cause of VEXAS syndrome

James A. Poulter, Jason C. Collins, Catherine Cargo, Ruth M. De Tute, Paul Evans, Daniela Ospina Cardona, David T. Bowen, Joanna R. Cunnington, Elaine Baguley, Mark Quinn, Michael Green, Dennis McGonagle, David B. Beck, Achim Werner, Sinisa Savic

Blood (2021) 137 (26): 3676–3681.

https://doi.org/10.1182/blood.2020010286

Published: 2021

Includes: Supplemental data

Journal Articles

A Phase 1b Study of Eltrombopag and Azacitidine in Patients with High Risk Myelodysplastic Syndromes and Related Disorders

Alex Sternberg, MRCP,FRCPath, Rebecca H. Boucher, BSc, MSc, PhD, Helen C Coulthard, BSc, Manoj Raghavan, MBBS, PhD MRCP, FRCPath, Dominic J. Culligan, MD, Aimee Jackson, BSc, MSc, Catherine Cargo, MB, PhD, Mike Dennis, MD, Marlen Metzner, MSc, Rachel Moore, BA, David Bowen, MD, Paresh Vyas, MRCP, FRCP, FRCPath

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-134227

Published: 2020

Journal Articles

Germline TET2 loss of function causes childhood immunodeficiency and lymphoma

Blood (2020) 136 (9): 1055–1066.

https://doi.org/10.1182/blood.2020005844

Published: 2020

Includes: Supplemental data

Journal Articles

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, PhD, Yasuhito Nannya, MD PhD, Tetsuichi Yoshizato, MD PhD, Robert P. Hasserjian, MD, Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Sean M. Devlin, PhD, Heinz Tuechler, Araxe Sarian, Luca Malcovati, MD, Francesc Sole, PhD, Detlef Haase, MD, Maria Creignou, Max Levine, MS, Ulrich Germing, MD, Catherine Cargo, MB, FRCPath, Yanming Zhang, MD, Juan Medina, MS, Juan E. Arango Ossa, BS, Julie Schanz, MD PhD, Arjan van de Loosdrecht, MD PhD, Martin Jädersten, MD PhD, John M. Bennett, MD, Magnus Tobiasson, MD PhD, Olivier Kosmider, PharmD, PhD, Matilde Y Follo, PhD, Felicitas Thol, MD, Ronald F Pinheiro, MD, Valeria Santini, MD, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio PS Santos, MD, Senji Kasahara, MD PhD, Takayuki Ishikawa, MD PhD, Hisashi Tsurumi, MD PhD, Akifumi Takaori-Kondo, MD PhD, Toru Kiguchi, Chantana Polprasert, MD, Virginia M. Klimek, MD, Michael R. Savona, MD, Monika Belickova, PhD, Christina Ganster, Lionel Ades, MD PhD, Matteo Giovanni Della Porta, MD, Alexandra Smith, PhD, Yesenia Werner, Minal A Patel, MPH, Agnes Viale, PhD, Katelynd Vanness, Donna S Neuberg, ScD, Kristen E. Stevenson, MS, Kamal Menghrajani, MD, Kelly Bolton, MD PhD, Pierre Fenaux, MD PhD, Andrea Pellagatti, Uwe Platzbecker, MD, Michael Heuser, MD, Peter Valent, MD, Shigeru Chiba, MD PhD, Yasushi Miyazaki, MD PhD, Carlo Finelli, Maria Teresa Voso, MD, Lee-Yung Shih, MD, Michaela Fontenay, MD PhD, Joop H. Jansen, PhD, José Cervera, MD PhD, Yoshiko Atsuta, MD PhD, Norbert Gattermann, MD, Benjamin L. Ebert, MD PhD, Rafael Bejar, MD PhD, Peter L Greenberg, MD, Mario Cazzola, MD, Eva Hellstrom Lindberg, MD PhD, Seishi Ogawa, MD PhD, Elli Papaemmanuil, PhD

Blood (2019) 134 (Supplement_1): 675.

https://doi.org/10.1182/blood-2019-129392

Published: 2019

Journal Articles

Targeted Sequencing Predicts the Development of Myeloid Malignancies and Clinical Outcome in Patients with Unexplained Cytopenia

Catherine Cargo, MB, FRCPath, Kelly Bolton, MD PhD, Tumas Beinortas, MBBS, Paul Glover, MSc, Michael Short, Alexandra Smith, PhD, Jan Taylor, PhD MSc, BSc, Paul A S Evans, PhD, Elli Papaemmanuil, PhD, Simon Crouch, PhD BA, MA, MSc

Blood (2019) 134 (Supplement_1): 1712.

https://doi.org/10.1182/blood-2019-131402

Published: 2019

Journal Articles

The use of targeted sequencing and flow cytometry to identify patients with a clinically significant monocytosis

Catherine Cargo, Matthew Cullen, Jan Taylor, Mike Short, Paul Glover, Suzan Van Hoppe, Alex Smith, Paul Evans, Simon Crouch

Blood (2019) 133 (12): 1325–1334.

https://doi.org/10.1182/blood-2018-08-867333

Published: 2019

Includes: Supplemental data

Journal Articles

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Blood (2018) 132 (Supplement 1): 1762.

https://doi.org/10.1182/blood-2018-99-111559

Published: 2018

Journal Articles

Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study

Steven Knapper, DM, Michael Dennis, MD, MRCP, FRCPath, Mark W Drummond, PhDMD, Robert K. Hills, MA, DPhil, MSc, Richard James Dillon, MA, PhD MRCP, FRCPath, Christopher Pocock, MD PhD, Dominic J. Culligan, Paresh Vyas, Daniel Wiseman, MB, ChB, Joanna Zabkiewicz, PhD, Marie Hodges, PhD MSc, Catherine Cargo, MB, FRCPath, Jan Taylor, PhD MSc, BSc, Laura Upton, Melissa Wright, David Bowen, MD PhD

Blood (2018) 132 (Supplement 1): 1818.

https://doi.org/10.1182/blood-2018-99-110356

Published: 2018

Journal Articles

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Results from the MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Allison Scotch, MD MPH, Robyn M. Scherber, MD, Marlene Bruso, MS, Heidi Elizabeth Kosiorek, MS, Amylou C. Dueck, PhD, Holly Geyer, MD, Veena D. S. Fauble, MD, Alessandro M. Vannucchi, Ana Kerguelen Fuentes, Christen Lykkegaard Andersen, PhD, Elisabeth Ejerblad, MD, Gunnar Birgegard, MD PhD, Peter L. Johansson, MD PhD, Bjorn Andreasson, David M Ross, MBBS, PhD FRACP, FRCPA, Federico Sackman, MD PhD, Jean-Loup Demory, MD PhD, Constantine S. Tam, MBBS, MD FRACP, FRCPA, Jan J. Michiels, PhD, Deepti Radia, MD, Joanne Ewing, PhD BMBS, BSc, FRPATH,, Frances Wadelin, MD, Robert N. Lown, MBBS, MRCP, MD, Mary Frances McMullin, MB,Bch BAO, MD FRCPath, Wunna Swe, Jonathan O. Cullis, MD, Nigel Sargant, BSc, FRPATH, MRCP,, Paul Moreton, MD MRCP, FRCPath, Catherine Cargo, MB, FRCPath, Mallika Sekhar, MBBS, MD FRCPath, FRCP, Satareh Shekouhi, Ruben A Mesa, MD

Blood (2017) 130 (Supplement 1): 1641.

https://doi.org/10.1182/blood.V130.Suppl_1.1641.1641

Published: 2017

Journal Articles

Mutational Profiling of Peripheral Blood and Bone Marrow Samples Discriminates Reactive Monocytosis from Chronic Myelomonocytic Leukaemia

Catherine Cargo, MB, FRCPath, Matt Cullen, PhD, Jan Taylor, PhD, Mike Short, BSc, Paul Evans, PhD, Simon Crouch, PhD

Blood (2016) 128 (22): 3181.

https://doi.org/10.1182/blood.V128.22.3181.3181

Published: 2016

Journal Articles

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Interim Results from the MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Allison H Scotch, MD MPH, Robyn M. Scherber, MD MPH, Nan Zhang, MS, Heidi E. Kosiorek, MS, Amylou C. Dueck, PhD, Holly Geyer, MD, Veena Fauble, MD, Alessandro M. Vannucchi, MD PhD, Ana Kerguelen Fuentes, Christen Lykkegaard Andersen, MD PhD, Elisabeth Ejerblad, MD, Gunnar Birgegard, MD PhD, Peter L. Johansson, MD PhD, Bjorn Andreasson, David M. Ross, MBBS, PhD FRACP, FRCPA, Federico Sackmann, MD, Jean-Loup Demory, MD, Constantine S. Tam, Jan J. Michiels, PhD, Deepti Radia, MBBS, MRCPI, FRCPath MSc, MD, Mohan Mahalakshmi, MD, Daniel Jennings, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Frances Wadelin, MD, Robert N Lown, MBBS, MDRes), MRCP, FRCPath, Victoria Drew, John Hudson, Mary Frances McMullin, MD, Wunna Swe, Jonathan O. Cullis, MD MB, BS, MA, FRCP, FRCPath, Nigel Sargant, BSc, FRPATH, MRCP,, Paul Moreton, MD MRCP, MRCPath, Mari Frances Kilner, MBBS,MRCP,FRCPath, Catherine Cargo, MB, FRCPath, Mallika Sekhar, MBBS,MDFRCPath,FRCP, Satareh Shekouhi, Ruben A. Mesa, MD

Blood (2016) 128 (22): 5479.

https://doi.org/10.1182/blood.V128.22.5479.5479

Published: 2016

Journal Articles

Pegylated-Interferon Treatment Is Safe and Efficient for Pregnant Patients with Essential Thrombocythaemia

Yan Beauverd, Arvind Pillai, MBBS, MRCP, FRCPath, Steven Knapper, DM BMBCh FRCPath MRCP, Catherine Cargo, MB MRCP FRCPath, Claire N. Harrison, Susan Robinson

Blood (2015) 126 (23): 1613.

https://doi.org/10.1182/blood.V126.23.1613.1613

Published: 2015

Journal Articles

Early Diagnosis of Myelodysplastic Syndromes Can be Improved By Deep Sequencing and Array Based Cytogenetics

Catherine Cargo, MB FRCPath, Nicola Rowbotham, PhD, Paul Evans, PhD, Sharon Barrans, PhD, Simon Crouch, PhD, Andrew Jack, PhD

Blood (2014) 124 (21): 167.

https://doi.org/10.1182/blood.V124.21.167.167

Published: 2014

Journal Articles

A Unified Prognostic Model for Myelodysplastic Syndrome and Acute Myeloid Leukaemia Based on Flow Cytometric Blast Count

Alexandra Smith, BSc PhD, Simon Crouch, MA PhD, Dan Painter, Eve Roman, Matt Cullen, Fiona Bennett, Catherine Cargo, MB, MRCP, Andrew Jack, PhD, MB

Blood (2011) 118 (21): 1736.

https://doi.org/10.1182/blood.V118.21.1736.1736

Published: 2011

NARROW

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

Novel somatic mutations in UBA1 as a cause of VEXAS syndrome

A Phase 1b Study of Eltrombopag and Azacitidine in Patients with High Risk Myelodysplastic Syndromes and Related Disorders

Germline TET2 loss of function causes childhood immunodeficiency and lymphoma

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Targeted Sequencing Predicts the Development of Myeloid Malignancies and Clinical Outcome in Patients with Unexplained Cytopenia

The use of targeted sequencing and flow cytometry to identify patients with a clinically significant monocytosis

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Results from the MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Mutational Profiling of Peripheral Blood and Bone Marrow Samples Discriminates Reactive Monocytosis from Chronic Myelomonocytic Leukaemia

Myeloproliferative Neoplasm Quality of Life (MPN-QOL) Study Group: Interim Results from the MPN Experimental Assessment of Symptoms By Utilizing Repetitive Evaluation (MEASURE) Trial

Pegylated-Interferon Treatment Is Safe and Efficient for Pregnant Patients with Essential Thrombocythaemia

Early Diagnosis of Myelodysplastic Syndromes Can be Improved By Deep Sequencing and Array Based Cytogenetics

A Unified Prognostic Model for Myelodysplastic Syndrome and Acute Myeloid Leukaemia Based on Flow Cytometric Blast Count

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American Society of Hematology

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ASH Publications

American Society of Hematology

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