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Salima Benbarche
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Journal Articles

Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity

Bin Lu, Pu Zhang, Sisi Chen, Salima Benbarche, Cynthia Castro, Nina Fox, Mohammad Abubakar, Jeetayu Biswas, Ruslan Soldatov, Richard Koche, Omar Abdel-Wahab
Journal: Blood
Blood (2023) 142 (Supplement 1): 242.
https://doi.org/10.1182/blood-2023-180913
Published: 2023
Journal Articles

Synthetic Introns Identify the Novel RNA Splicing Factor GPATCH8 As Required for Mis-Splicing Induced By SF3B1 Mutations

Salima Benbarche, Jose Maria Bello Pineda, Laura Baquero Galvis, Bo Liu, Jeetayu Biswas, Eric Wang, K. Ashley Lyttle, Alexander M. Lewis, Martina Sarchi, Sanjoy Mehta, Ralph Garippa, Juliana Ortiz-Pacheco, Zhuoning Li, Mara Monetti, Robert Stanley, Sergei Doulatov, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2023) 142 (Supplement 1): 3.
https://doi.org/10.1182/blood-2023-179848
Published: 2023
Journal Articles

RAF-Independent MEK Mutations Drive Histiocytic Neoplasms In Vivo and Are Sensitive to Single-Agent ERK Inhibition in Patients

Benjamin H Durham, Michael E Singer, Salima Benbarche, Caroline Erickson, Jahan Rahman, David B. Solit, Matthew Witkowski, Neal Rosen, Omar Abdel-Wahab, Eli L Diamond
Journal: Blood
Blood (2022) 140 (Supplement 1): 1098–1100.
https://doi.org/10.1182/blood-2022-163575
Published: 2022
Journal Articles

Impaired RAS Proteolysis Drives Clonal Hematopoietic Transformation

Sisi Chen, Rahul S. Vedula, Pau Castel, Antonio Cuevas Navarro, Simon J. Hogg, Eric Wang, Xiaoli Mi, Salima Benbarche, Katherine Knorr, Won Jun Kim, Hana Cho, Caroline Erickson, Michael E Singer, Daniel Cui, Benjamin H. Durham, Daichi Inoue, Sebastien Monette, Neal Rosen, Frank McCormick, R. Coleman Lindsley, Jr., Omar Abdel-Wahab
Journal: Blood
Blood (2021) 138 (Supplement 1): 356.
https://doi.org/10.1182/blood-2021-147026
Published: 2021
Journal Articles

Splicing factor mutations in hematologic malignancies

Sisi Chen, Salima Benbarche, Omar Abdel-Wahab
Journal: Blood
Blood (2021) 138 (8): 599–612.
https://doi.org/10.1182/blood.2019004260
Published: 2021
Journal Articles

Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation

Anna S Nam, MD, Neville Dusaj, MS, Franco Izzo, PhD, Rekha Murali, MS, Tarek H Mouhieddine, MD, Robert M Myers, Jesus Sotelo, Salima Benbarche, PhD, Federico Gaiti, PhD, Sabrin Tahri, MD MSc, Omar Abdel-Wahab, MD, Irene M. Ghobrial, MD, Ronan Chaligne, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-142574
Published: 2020
Journal Articles

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms

Justin Taylor, Xiaoli Mi, Khrystyna North, Moritz Binder, Alexander Penson, Terra Lasho, Katherine Knorr, Michael Haddadin, Bo Liu, Joseph Pangallo, Salima Benbarche, Daniel Wiseman, Ayalew Tefferi, Stephanie Halene, Yang Liang, Mrinal M. Patnaik, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2020) 136 (13): 1477–1486.
https://doi.org/10.1182/blood.2020006868
Published: 2020
Includes: Supplemental data
Journal Articles

Crispri-Based Screening of Clustered Regulatory Elements Reveals Novel Leukemia Dependencies

Salima Benbarche, PhD, Cécile K Lopez, Thomas Mercher, PhD, Camille Lobry, PhD MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 654.
https://doi.org/10.1182/blood-2018-99-111865
Published: 2018