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Journal Articles

Reduced overall survival in TP53-mutated ccus is driven by prior cytotoxic exposure and cytopenia rather than leukemic progression

Blood (2025) 146 (Supplement 1): 5643.

https://doi.org/10.1182/blood-2025-5643

Published: 2025

Journal Articles

17p loss in TP53-non-mutated myeloid neoplasms confers survival comparable to TP53-mutated disease

Blood (2025) 146 (Supplement 1): 3858.

https://doi.org/10.1182/blood-2025-3858

Published: 2025

Journal Articles

Consideration of genomic determinants improves the diagnostic accuracy of oligomonocytic chronic myelomonocytic leukemia

Blood (2025) 146 (Supplement 1): 3849.

https://doi.org/10.1182/blood-2025-3849

Published: 2025

Journal Articles

CMML2AML: Machine-learning discovery of co-mutations predictive of blast transformation in chronic myelomonocytic leukemia

Blood (2025) 146 (Supplement 1): 3844.

https://doi.org/10.1182/blood-2025-3844

Published: 2025

Journal Articles

Treatment-requiring paroxysmal nocturnal hemoglobinuria in association with myeloproliferative neoplasms (MPNs): Clinical correlations and outcomes

Priyansh Faldu, Rania Abdelaziz, Muhammad Yousuf, Animesh Pardanani, Mrinal Patnaik, Ayalew Tefferi, Naseema Gangat

Blood (2025) 146 (Supplement 1): 3188.

https://doi.org/10.1182/blood-2025-3188

Published: 2025

Journal Articles

Myeloproliferative neoplasm driver mutations (JAK2/CALR/MPL) in chronic myelomonocytic leukemia are associated with an increased risk of blast transformation

Muhammad Yousuf, Saubia Fathima, Priyansh Faldu, Ali Alsugair, Abiola Bolarinwa, Andrew Cannon, Terra Lasho, Abhishek Mangaonkar, Kaaren Reichard, Rong He, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2067.

https://doi.org/10.1182/blood-2025-2067

Published: 2025

Journal Articles

A phase 2, open-label study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of DISC-3405 in participants with polycythemia vera (PV)

Blood (2025) 146 (Supplement 1): 2053.

https://doi.org/10.1182/blood-2025-2053

Published: 2025

Journal Articles

Clonal persistence and early cooperative mutations shape transformation in myelofibrosis

Noushin Farnoud, Kamal Menghrajani, Paola Guglielmelli, Christopher Famulare, Erin McGovern, Giuseppe Gaetano Loscocco, Andriy Derkach, Andrew Dunbar, Naseema Gangat, Vikas Gupta, Andrea Arruda, Taghi Manshouri, Srdan Verstovsek, Andrew Kuykendall, Vincent Ho, Auro Viswabandya, Joachim Deeg, Thomas Monahan, Tania Jain, Jeanne Palmer, Alla Keyzner, Aaron Gerds, Alexandra Gomez-Arteaga, Nikolai Podoltsev, Roni Tamari, Helen Ajufo, Satyajit Kosuri, Haris Ali, Idoroenyi Amanam, Jordan Chervin, Minal Patel, Jesús Gutiérrez-Abril, Sarun Sereewattanawoot, Juan Arango Ossa, Francesco Passamonti, Francesco Maura, Maymona Abdelmagid, Ahmed Abdelrheem, Yassin Bashir, Muhammad Yousuf, Animesh Pardanani, Kapila Viges, David Shoultz, Rick Winneker, Omar Abdel-Wahab, John Mascarenhas, Ronald Hoffman, Ross Levine, Elli Papaemmanuil, Alessandro Vannucchi, Ayalew Tefferi, Raajit Rampal

Blood (2025) 146 (Supplement 1): 2046.

https://doi.org/10.1182/blood-2025-2046

Published: 2025

Journal Articles

RALLY MF: A phase 2 Study of DISC-0974, an anti-hemojuvelin antibody, in patients with myelofibrosis and anemia

Naseema Gangat, Ayalew Tefferi, Prithviraj Bose, Elizabeth Hexner, Laura Michaelis, Aaron Gerds, Akriti Jain, Prioty Islam, Raajit Rampal, Ronan Swords, Moshe Talpaz, Kristen Pettit, Sima Bhatt, Akshay Buch, Olivia Pelletier, Will Savage, Anna Halpern

Blood (2025) 146 (Supplement 1): 2042.

https://doi.org/10.1182/blood-2025-2042

Published: 2025

Journal Articles

Next-generation sequencing panel for hereditary erythrocytosis identifies genomic variants in over half of adults with otherwise unexplained erythrocytosis

Mahsa Rezasoltani, Jennifer Herrick, Aruna Rangan, Xi Zhang, Animesh Pardanani, Ayalew Tefferi, Naseema Gangat

Blood (2025) 146 (Supplement 1): 2877.

https://doi.org/10.1182/blood-2025-2877

Published: 2025

Journal Articles

Myeloproliferative neoplasms-unclassifiable (MPN-U): A carefully curated series of 30 Mayo Clinic patients

Rania Abdelaziz, Priyansh Faldu, Saubia Fathima, Kaaren Reichard, Rong He, Cinthya Mendoza Zepeda, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 7314.

https://doi.org/10.1182/blood-2025-7314

Published: 2025

Journal Articles

Identification of red cell distribution width as a key predictor of leukemic transformation in polycythemia vera and essential thrombocythemia: A machine learning approach involving 10,560 cases

Lior Rokach, Tamar Tadmor, Rania Abdelaziz, Guy Melamed, Priyansh Faldu, Hilel Alapi, Muhammad Yousuf, Merry Nakhleh, Animesh Pardanani, Kaaren Reichard, Rong He, Naseema Gangat, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2021.

https://doi.org/10.1182/blood-2025-2021

Published: 2025

Journal Articles

DIPSS-R: A revised age-agnostic clinical risk model for chronic phase primary myelofibrosis

Ayalew Tefferi, Alessandro Vannucchi, Yassin Bashir, Ahmed Abdelrheem, Maymona Abdelmagid, Giuseppe Gaetano Loscocco, leonardo Signori, Giulia Borgi, Valentina Boldrini, Kebede Begna, Kaaren Reichard, Rong He, Cinthya Mendoza, Tiziano Barbui, Francesco Passamonti, Animesh Pardanani, Naseema Gangat, Paola Guglielmelli

Blood (2025) 146 (Supplement 1): 84.

https://doi.org/10.1182/blood-2025-84

Published: 2025

Journal Articles

Risk-adjusted comparison of survival in chronic myelomonocytic leukemia with and without allogeneic stem cell transplant: Mayo Clinic experience in 775 consecutive patients

Blood (2025) 146 (Supplement 1): 5636.

https://doi.org/10.1182/blood-2025-5636

Published: 2025

Journal Articles

Integrated prognostic model for TP53‑mutated myeloid neoplasms across all myeloid neoplasm subtypes

Blood (2025) 146 (Supplement 1): 2087.

https://doi.org/10.1182/blood-2025-2087

Published: 2025

Journal Articles

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

Blood (2025) 146 (Supplement 1): 2081.

https://doi.org/10.1182/blood-2025-2081

Published: 2025

Journal Articles

Validation of blast and blast-mol risk models in chronic myelomonocytic leukemia: Mayo-humanitas collaborative project involving 1,101 patients

Saubia Fathima, Muhammad Yousuf, Priyansh Faldu, Ali Alsugair, Clifford Csizmar, Merry Nakhleh, Abhishek Mangaonkar, Animesh Pardanani, Luca Lanino, Alessia Campagna, Giulia Maggioni, Kaaren Reichard, Rong He, Naseema Gangat, Mrinal Patnaik, Matteo Della Porta, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2077.

https://doi.org/10.1182/blood-2025-2077

Published: 2025

Journal Articles

MAPS-R: International consensus classification-guided revision of the mayo alliance prognostic system for systemic mastocytosis

Ayalew Tefferi, Fnu Aperna, Mahesh Kumar, Maymona Abdelmagid, Joseph Butterfield, Thanai Pongdee, Cecilia Arana Yi, Daniel Arber, Attilio Orazi, Dong Chen, Kaaren Reichard, Naseema Gangat, Animesh Pardanani

Blood (2025) 146 (Supplement 1): 2017.

https://doi.org/10.1182/blood-2025-2017

Published: 2025

Journal Articles

CSF3R-mutated chronic neutrophilic leukemia: A two-center study of 44 consecutive patients

Abiola Bolarinwa, Natasha Szuber, Janick Caron-L'Ecuyer, Aref Al-Kali, William Hogan, Mithun Shah, James Foran, Talha Badar, Kaaren Reichard, Rong He, Naseema Gangat, Cinthya Mendoza, Michelle Elliott, Animesh Pardanani, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2013.

https://doi.org/10.1182/blood-2025-2013

Published: 2025

Journal Articles

Acute leukemia during pregnancy: A three-decade Mayo Clinic experience

Brittany Kimball, Antoine Saliba, Mahsa Rezasoltani, Kristen McCullough, William Hogan, Mrinal Patnaik, Isla Johnson, Clifford Csizmar, Aldo Acosta Medina, Aref Al-Kali, Hassan Alkhateeb, Kebede Begna, Animesh Pardanani, Nandita Khera, Mark Litzow, Ayalew Tefferi, Naseema Gangat

Blood (2025) 146 (Supplement 1): 6408.

https://doi.org/10.1182/blood-2025-6408

Published: 2025

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Reduced overall survival in TP53-mutated ccus is driven by prior cytotoxic exposure and cytopenia rather than leukemic progression

17p loss in TP53-non-mutated myeloid neoplasms confers survival comparable to TP53-mutated disease

Consideration of genomic determinants improves the diagnostic accuracy of oligomonocytic chronic myelomonocytic leukemia

CMML2AML: Machine-learning discovery of co-mutations predictive of blast transformation in chronic myelomonocytic leukemia

Treatment-requiring paroxysmal nocturnal hemoglobinuria in association with myeloproliferative neoplasms (MPNs): Clinical correlations and outcomes

Myeloproliferative neoplasm driver mutations (JAK2/CALR/MPL) in chronic myelomonocytic leukemia are associated with an increased risk of blast transformation

A phase 2, open-label study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of DISC-3405 in participants with polycythemia vera (PV)

Clonal persistence and early cooperative mutations shape transformation in myelofibrosis

RALLY MF: A phase 2 Study of DISC-0974, an anti-hemojuvelin antibody, in patients with myelofibrosis and anemia

Next-generation sequencing panel for hereditary erythrocytosis identifies genomic variants in over half of adults with otherwise unexplained erythrocytosis

Myeloproliferative neoplasms-unclassifiable (MPN-U): A carefully curated series of 30 Mayo Clinic patients

Identification of red cell distribution width as a key predictor of leukemic transformation in polycythemia vera and essential thrombocythemia: A machine learning approach involving 10,560 cases

DIPSS-R: A revised age-agnostic clinical risk model for chronic phase primary myelofibrosis

Risk-adjusted comparison of survival in chronic myelomonocytic leukemia with and without allogeneic stem cell transplant: Mayo Clinic experience in 775 consecutive patients

Integrated prognostic model for TP53‑mutated myeloid neoplasms across all myeloid neoplasm subtypes

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

Validation of blast and blast-mol risk models in chronic myelomonocytic leukemia: Mayo-humanitas collaborative project involving 1,101 patients

MAPS-R: International consensus classification-guided revision of the mayo alliance prognostic system for systemic mastocytosis

CSF3R-mutated chronic neutrophilic leukemia: A two-center study of 44 consecutive patients

Acute leukemia during pregnancy: A three-decade Mayo Clinic experience

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