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Nicolas Duployez
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Journal Articles

Fludarabine and cytarabine is not superior to high dose cytarabine as consolidation therapy in standard risk AML in children: Results from the international Phase III MyeChild01 trial

Free
Brenda Gibson, André Baruchel, Andrew Moore, Shanna Maycock, Owen Smith, Geoff Shenton, Cécile Renard, Nicholas Heaney, Anna Lawson, Persis Amrolia, Paul Saultier, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Siobhan Cross, Paul Virgo, Lucy Wheeler, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy CUCCUINI, Marina Lafage-Pochitaloff, Claude Preudhomme, Pierre Hirsch, Gareth Veal, David Gillis, Pam Kearns, Guy Leverger, Philip Ancliff, Aimee Jackson, Arnaud Petit
Journal: Blood
Blood (2025) 146 (Supplement 1): 879.
https://doi.org/10.1182/blood-2025-879
Published: 2025
Journal Articles

Clinical impact of FLT3 microclones on outcomes in patients with newly diagnosed FLT3-ITD negative AML: A subanalysis from the pethema quiwi trial

Free
Claudia Sargas, Augustin Boudry, Pilar Lloret Madrid, Nicolas Duployez, Eva Barragán, Rosa Ayala Diaz, Rafael Colmenares, Carmen Chillon, Maria Calasanz, Maria Jose Larrayoz, Rebeca Rodriguez Veiga, Juan Miguel Bergua Burgues, Lorenzo Algarra, Carmen Botella, Eduardo Rodríguez-Arbolí, Teresa Bernal Del Castillo, Mar Tormo, Maria Calbacho, Olga Salamero, Josefina Serrano, Victor Noriega Concepción, Juan Antonio López-López, Susana Vives, José Luis López Lorenzo, Mercedes Colorado, María-Belén Vidriales, Raimundo García-Boyero, Maria Teresa Olave Rubio, Pilar Herrera Puente, Olga Arce-Fernández, Manuel Barrios García, David Martinez-Cuadron, Jorge Labrador, Claude Preudhomme, Pau Montesinos
Journal: Blood
Blood (2025) 146 (Supplement 1): 1719.
https://doi.org/10.1182/blood-2025-1719
Published: 2025
Journal Articles

Only young age and genetics retain prognostic value for 2-year relapse-free survival in AML

Free
Wissam Mahrez, Céline Berthon, Laurene Fenwarth, Carine Hauspie, Nicolas Duployez, Claude Preudhomme, Magalie Joris, Jean Pierre Marolleau, Delphine Lebon
Journal: Blood
Blood (2025) 146 (Supplement 1): 3382.
https://doi.org/10.1182/blood-2025-3382
Published: 2025
Journal Articles

Molecular landscape and clonal evolution in minor versus major BCR::ABL1 chronic myeloid leukemia under tyrosine kinase inhibition : A Study from the french group fi-LMC

Free
Benjamin Podvin, Olivier Nibourel, Sandrine Hayette, Valerie Coiteux, Rathana KIM, Lucie Rigolot, Stéphanie Dulucq, Augustin Boudry, Wayne-Corentin Lambert, Pascale Flandrin-Gresta, Ivan Sloma, Christophe Roumier, Marie Balsat, Sandrine Loron, Chloe Li, Sandrine Geffroy, Jean-Michel Cayuela, Francoise Huguet, Francois-Xavier Mahon, Franck Nicolini, Delphine Rea, Claude Preudhomme, Nicolas Duployez, Catherine Roche-Lestienne
Journal: Blood
Blood (2025) 146 (Supplement 1): 77.
https://doi.org/10.1182/blood-2025-77
Published: 2025
Journal Articles

Comprehensive mutational profiling and clinical outcome of adults AML with NUP98 rearrangement

Free
Ducourneau Benoit, Arnaud Pages, Stéphanie Struski, Matthieu Decamp, Emmanuel Raffoux, Céline Berthon, Laurene Fenwarth, Vincent Marmouset, Cecile Pautas, Thomas Cluzeau, Delphine Lebon, Madalina Uzunov, Patricio Pereyra, Mael Heiblig, Jean-Valère Malfuson, Laure Farnault, Pierre-Yves Dumas, Julia HIEULLE, Sarah Bertoli, Sylvain Chantepie, Nathalie Auger, Audrey Bidet, Marie Joelle Mozziconacci, Augustin Boudry, Isabelle Luquet, Laureen Chat, Romain Loyaux, Lina EL-MURR, Emmanuelle Clappier, Claude Gardin, Mathilde Hunault, Stephane De Botton, Arnaud Pigneux, Dominique Penther, Eric Delabesse, Raphael Itzykson, Claude Preudhomme, Herve Dombret, Christian Recher, Nicolas Duployez, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 7002.
https://doi.org/10.1182/blood-2025-7002
Published: 2025
Journal Articles

Impact of midostaurin in younger AML patients intensively treated with high-dose anthracycline

Free
Pierre-Yves Dumas, Mathieu Leclerc, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Thibaut Leguay, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Sylvain Chantepie, Mael Heiblig, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Delphine Lebon, Madalina Uzunov, Jean-Valère Malfuson, Thomas Cluzeau, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Eric Delabesse, Jean-François Hamel, Raphael Itzykson, Claude Preudhomme, Stephane De Botton, Nicolas Duployez, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2025-1682
Published: 2025
Journal Articles

Secondary-type acute myeloid leukemia is associated with a higher risk of invasive fungal infection during intensive induction therapy. a correlative study on the ALFA 0702 trial.

Free
Jean-Eudes Fahrner, Mauricette Michallet, Laurene Fenwarth, Mohamad Sobh, Stéphane Morisset, Alexandre Deloire, Emmanuel Raffoux, Stephane De Botton, Sylvain Chantepie, Stephane Girault, Céline Berthon, Sarah Bertoli, Stephane Lepretre, Pierre Yves Dumas, Juliette Lambert, Delphine Lebon, Cecile Pautas, Jean Valère Malfuson, Norbert Vey, Thorsten Braun, Felipe Suarez, Aline Schmidt, Remy Gressin, Caroline Bonmati, Karine Celli-Lebras, Mael Heiblig, Mohamed El-Hamri, Claude Preudhomme, Hervé Dombret, Anne Bergeron, Nicolas Duployez, Raphael Itzykson
Journal: Blood
Blood (2025) 146 (Supplement 1): 994.
https://doi.org/10.1182/blood-2025-994
Published: 2025
Journal Articles

Induction chemotherapy with a single anthracycline-containing cycle in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Cecile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Martin Carre, Sylvain Chantepie, Pierre Peterlin, Maria Pilar Gallego Hernanz, Juliette Lambert, Corentin Orvain, Romain Guieze, Pascal Turlure, Celestine Simand, Emilie Lemasle, Chantal Himberlin, Caroline Bonmati, Jean Valère Malfuson, Delphine Lebon, Thomas Cluzeau, Emmanuelle Tavernier, Jean-Baptiste Micol, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Anne Huynh, Thibaut Leguay, Isabelle Luquet, Dominique Penther, Nicolas Duployez, Eric Delabesse, Claude Preudhomme, Herve Dombret, Jean-François Hamel, Arnaud Pigneux, Hunault-Berger Mathilde
Journal: Blood
Blood (2025) 146 (Supplement 1): 43.
https://doi.org/10.1182/blood-2025-43
Published: 2025
Journal Articles

Therapy-related core binding factor Acute Myeloid Leukemia – a Study of the french acute leukemia intergroup

Free
Mathilde Chanut, Loïc Vasseur, Matthieu Duchmann, Pierre Hirsch, Céline Berthon, Mael Heiblig, Thorsten Braun, Mathieu Leclerc, Jean Valère Malfuson, Delphine Lebon, Madalina Uzunov, Jean-Noel Bastie, Gian Matteo Pica, Marie-Anne Hospital, Thomas Cluzeau, Juliette Lambert, Lauris Gastaud, Karine Celli-Lebras, Arnaud Pigneux, Stephane De Botton, Christian Recher, Claude Preudhomme, Eric Jourdan, Herve Dombret, Nicolas Boissel, Nicolas Duployez, Raphael Itzykson, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 37.
https://doi.org/10.1182/blood-2025-37
Published: 2025
Journal Articles

Randomized study of high-dose cytarabine with or without dexamethasone as post-remission therapy in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Marie-Anne Hospital, Thibaut Leguay, Martin Carre, Corentin Orvain, Caroline Bonmati, Emmanuel Raffoux, Celestine Simand, Romain Guieze, Jamilé Frayfer, Juliette Lambert, Sylvain Chantepie, Marc Bernard, Pierre Peterlin, Magda Alexis, Pascal Turlure, Cecile Pautas, Sarah Bertoli, Ludovic Gabellier, Edouard Forcade, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Pierre-Yves Dumas, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Herve Dombret, Arnaud Pigneux, Hunault-Berger Mathilde, Stephane De Botton
Journal: Blood
Blood (2025) 146 (Supplement 1): 881.
https://doi.org/10.1182/blood-2025-881
Published: 2025
Journal Articles

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

Free
Clifford Csizmar, Guillermo Montalban-Bravo, Leila Cysique-Foinlan, Anuya Natu, Terra Lasho, Christy Finke, Aref Al-Kali, Hassan Alkhateeb, Ali Alsugair, Kebede Begna, Saubia Fathima, Naseema Gangat, Abhishek Mangaonkar, Antoine Saliba, Ayalew Tefferi, Margot Morabito, Nathalie Droin, Cyril Quivoron, Benjamin Podvin, Nicolas Duployez, Olivier Kosmider, Christophe Marzac, Sylvain Thépot, Mathieu Meunier, Céline Berthon, Thorsten Braun, Christophe Willekens, Stephane De Botton, Lionel Ades, Alexandre Bazinet, Kelly Chien, Danielle Hammond, Courtney DiNardo, Tapan Kadia, Rashmi Kanagal-Shamanna, Sanam Loghavi, Naveen Pemmaraju, Farhad Ravandi, Koji Sasaki, Hagop Kantarjian, Pierre Fenaux, Eric Solary, Guillermo Garcia-Manero, Aline Renneville, Mrinal Patnaik
Journal: Blood
Blood (2025) 146 (Supplement 1): 2081.
https://doi.org/10.1182/blood-2025-2081
Published: 2025
Journal Articles

Clonal hematopoiesis of indeterminate potential in coronary disease patients: A 24-year follow-up

Free
Annabelle Dupont, Cynthia Carbonneau, Laurene Fenwarth, Flavien Vincent, Nicolas Duployez, Mickael Rosa, Melanie Daniel, Bart Staels, Claude Preudhomme, Eric Van Belle, Sophie Susen
Journal: Blood
Blood (2025) 146 (Supplement 1): 4951.
https://doi.org/10.1182/blood-2025-4951
Published: 2025
Journal Articles

Real-life CD34+CD38- leukemic stem cell (LSC) flow quantification in adult AML at diagnosis independently predicts survival of intensively but not AZA-VEN treated patients: A study of prospective observational ALFA-PPP acute leukemia french association

Free
Adriana Plesa, Alexandra COELHO, Stéphanie Mathis, Veronique Saada, Isabelle Arnoux, Valerie Bardet, Florent Dumezy, Clémentine Chauvel, Jaja Zhu, Vanessa Nivaggioni, Delphine Manzoni, Iole Oster, Dominique Penther, Nicolas Duployez, Karine Celli-Lebras, Nicole Raus, Emmanuel Raffoux, Lionel Ades, Christophe Willekens, Jean-Baptiste Micol, Stephane De Botton, Laure Farnault, Sylvain Chantepie, Thomas Cluzeau, Julia HIEULLE, Céline Berthon, Ahmad Aljijakli, Claire Bories, Kevin-James Wattebled, Renaud Buffet, Raphael Itzykson, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2025) 146 (Supplement 1): 3483.
https://doi.org/10.1182/blood-2025-3483
Published: 2025
Journal Articles

Frequency and impact of FLT3-ITD microclones in younger AML patients

Free
Nicolas Duployez, Romane Joudinaud, Augustin Boudry, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean-François Hamel, Stephane De Botton, Arnaud Pigneux, Herve Dombret, Christian Recher, Claude Preudhomme, Pierre-Yves Dumas
Journal: Blood
Blood (2025) 146 (Supplement 1): 456.
https://doi.org/10.1182/blood-2025-456
Published: 2025
Journal Articles

Real-world patterns of treatment intensity and prognostic model performance in older AML: Insights from the french ALFA-PPP cohort

Free
Lin-Pierre Zhao, Céline Berthon, Lauren Fenwarth, Stephane De Botton, Thomas Cluzeau, Laure Farnault, Sylvain Chantepie, Pierre Arnautou, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Ahmad Aljijakli, Isabelle Plantier, Ollivier Legrand, Juliette Lambert, Christophe Willekens, Emmanuel Raffoux, Claire Bories, Emilie Lemasle, Kevin-James Wattebled, Ambroise Marçais, Celia Salanoubat, Pascal Turlure, Jamilé Frayfer, Benjamin Carpentier, Madalina Uzunov, Reda Garidi, Ioana Vaida, Renaud Buffet, Alexandra COELHO, Karine Celli-Lebras, Raphael Itzykson, Claude Preudhomme, Nicolas Duployez, Hervé Dombret, Lionel Ades
Journal: Blood
Blood (2025) 146 (Supplement 1): 454.
https://doi.org/10.1182/blood-2025-454
Published: 2025
Journal Articles

Real life treatments and outcomes of older patients aged more than 60 years with FLT3-mutated acute myeloid leukemia: Report from the multicentric french observational ALFA-PPP study

Free
Ramy Rahmé, Emmanuel Raffoux, Lionel Ades, Stephane De Botton, Nicolas Duployez, Alexandra COELHO, Jean-Baptiste Micol, Sylvain Chantepie, Thomas Cluzeau, Delphine Lebon, Pierre Arnautou, Mathieu Leclerc, Laure Farnault, Ollivier Legrand, Ahmad Aljijakli, Céline Berthon, Juliette Lambert, Claire Bories, Ambroise Marçais, Julia HIEULLE, Celia Salanoubat, Pascal Turlure, Kevin-James Wattebled, Benjamin Carpentier, Jamile Frayfer, Ioana Vaida, Madalina Uzunov, Reda Garidi, Luca Inchiappa, Karine Celli-Lebras, Dominique Penther, Raynier Devillier, Raphael Itzykson, Claude Preudhomme, Renaud Buffet, Herve Dombret, Thorsten Braun
Journal: Blood
Blood (2025) 146 (Supplement 1): 449.
https://doi.org/10.1182/blood-2025-449
Published: 2025
Journal Articles

High prognostic value of NGS-based measurable residual FLT3-ITD in AML patients positive for FLT3-ITD treated with ponatinib in combination with cytarabine in first complete remission.

Free
Laurene Fenwarth, Claude Preudhomme, Thibaut Leguay, Augustin Boudry, Nais Prade, Eric Delabesse, Lisa Boureau, Audrey Bidet, Sebastian Stasik, Christian Thiede, Sandrine Geffroy, Melody Fort, Juliette Lambert, Emmanuel Raffoux, Sylvain Chantepie, Ollivier Legrand, Pierre Peterlin, Herve Dombret, Arnaud Pigneux, Pierre Yves Dumas, Nicolas Duployez, Philippe Rousselot
Journal: Blood
Blood (2025) 146 (Supplement 1): 5295.
https://doi.org/10.1182/blood-2025-5295
Published: 2025
Journal Articles

Outcomes of NPM1-mutated AMLs in first hematological relapse and prognostic value of MRD

Free
Sofiane Fodil, Matthieu Duchmann, Edoardo Tamellini, Anne Couprie, Rathana KIM, Pierre-Edouard Debureaux, Marie Passet, Nicolas Duployez, Etienne Lengline, Mattoe Dragani, Laureen Chat, Reinaldo Dal Bello, Matthieu Jestin, Lin-Pierre Zhao, Regis Peffault De Latour, Marie Sebert, Delphine Lebon, Nicolas Boissel, Lionel Ades, Emmanuelle Clappier, Emmanuel Raffoux, Raphael Itzykson
Journal: Blood
Blood (2025) 146 (Supplement 1): 5294.
https://doi.org/10.1182/blood-2025-5294
Published: 2025
Journal Articles

Treatments and outcomes of adult patients with TP53-mutated acute myeloid leukemia (AML) in the real-life –Report of the prospective french observational ALFA-PPP study.

Free
Jean-Baptiste Micol, Raphael Itzykson, Laure Farnault, Thomas Cluzeau, Jean-Valère Malfuson, Sylvain Chantepie, Delphine Lebon, Claire Bories, Ramy Rahme, Mathieu Leclerc, Ahmad Aljijakli, Laurene Fenwarth, Alexandra COELHO, Renaud Buffet, Emmanuel Raffoux, Christophe Willekens, Marie Sebert, Stephane De Botton, Claude Preudhomme, Herve Dombret, Dominique Penther, Nicolas Duployez, Elsa Bernard
Journal: Blood
Blood (2025) 146 (Supplement 1): 6386.
https://doi.org/10.1182/blood-2025-6386
Published: 2025
Journal Articles

Diagnostic relevance of SH2B3 mutations in suspected myeloid malignancies: Insights from a large-scale NGS-based screening study

Free
Leïla BEN DHIA, Mathieu Wemeau, Laurene Fenwarth, Alice Marceau-Renaut, Elise Fournier, Ducourneau Benoit, Sabine Tricot, Manon Deschildt, Pascal Huchette, Stéphane DARRE, Ilyes BENHALIMA, Emilie MARGAT, Claire Bories, Maxime DUFOSSE, Thomas Boyer, Etienne Paubelle, Amandine Charbonnier, Delphine Lebon, Julia HIEULLE, Sophie Dennetiere, Zoé MALBRANQUE, Adrien Daniel, Judith BRUGE, Laurent Pascal, Jan BRIJS, Benjamin Carpentier, Alexandre Willaume, Valerie Coiteux, Laure Goursaud, Claude Preudhomme, Olivier NIBOUREL, Nicolas Duployez
Journal: Blood
Blood (2025) 146 (Supplement 1): 2016.
https://doi.org/10.1182/blood-2025-2016
Published: 2025