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Arnaud Pigneux
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Journal Articles

Real-World Treatment Patterns and Clinical Outcomes in Newly Diagnosed Acute Myeloid Leukemia with and without mIDH1 Treated with Intensive Chemotherapy from an International Real-World Database (REAL-IDH)

Joshua F. Zeidner, Priyanka Mehta, Benyam Muluneh, Sarah Bertoli, Pierre-Yves Dumas, Arnaud Pigneux, Cédric Fernandez, Hélène Derrien, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 3816.
https://doi.org/10.1182/blood-2023-188548
Published: 2023
Journal Articles

Tyrosine Kinase Inhibitors with Intensive Chemotherapy in AML with t(9;22)(q34.1;q11.2)/ BCR::ABL1 : Time to Reconsider Prognostic Risk? a Study from the Dataml Registry

Camille Gondran, Pierre-Yves Dumas, Audrey Bidet, Emilie Bérard, Suzanne Tavitian, Thibaut Leguay, Françoise Huguet, Isabelle Luquet, Émilie Klein, Audrey Sarry, Anne-Charlotte De Grande, Eric Delabesse, Édouard Forcade, Cécile Borel, Arnaud Pigneux, Christian Recher, Laetitia Largeaud, Sarah Bertoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2023-180817
Published: 2023
Journal Articles

Acute Myeloid Leukemia Patients Who Stopped Venetoclax or/and Azacytidine for Other Reasons Than Progression Have a Prolonged Treatment Free Remission and Overall Survival. a Filo Study

Sylvain Garciaz, Sarah Bertoli, David A Sallman, Justine Decroocq, Pierre-Yves Dumas, Amine Belhabri, Corentin Orvain, Gaspar Aspas Requena, Celestine Simand, Kamel Laribi, Martin Carré, Alberto Santagostino, Ludovic Gabellier, Marie Anne Hospital, Ariane Mineur, Arnaud Pigneux, Norbert Vey, Christian Récher
Journal: Blood
Blood (2023) 142 (Supplement 1): 161.
https://doi.org/10.1182/blood-2023-185437
Published: 2023
Journal Articles

Long-Term Real-World Experience of CPX-351 in Combined French-Italian Cohorts Identified High Rate of Negative Measurable Residual Disease (MRD) and Prolonged Overall Survival

Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahmé, Sarah Bertoli, Livio Pagano, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Mohamad Mohty, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina Dargenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christian Recher, Norbert Vey, Francesco Grimaldi, Lionel Ades, Roberto Massimo Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 4255.
https://doi.org/10.1182/blood-2023-177951
Published: 2023
Journal Articles

Safety and Tolerability of AZD0466 As Monotherapy for Patients with Advanced Hematologic Malignancies. Results from a Phase I/II Trial

Shukaib Arslan, Giovanni Marconi, Giovanni Martinelli, Shaun Fleming, Antonio Curti, Shira N. Dinner, James S Blachly, Matteo Giovanni Della Porta, Ashish Bajel, Tim Sauer, Martina Crysandt, Arnaud Pigneux, Lars Fransecky, Claudia D Baldus, Marina Y. Konopleva, Yotvat Marmor, Shringi Sharma, Nairouz Elgeioushi, Patricia Cheung, Emily Rowe, Ekaterina Jahn, Ting Yu, Jamal Saeh, Raoul Tibes, Fathima Zumla Cader, Nitin Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 5907.
https://doi.org/10.1182/blood-2023-179168
Published: 2023
Journal Articles

Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Gaspar Aspas Requena, Pierre Yves Dumas, Rebeca Rodriguez Veiga, Sarah Bertoli, Cristina Gil, Celestine Simand, Fernando Jesús Ramos-Ortega, Pierre Peterlin, Josefina Serrano, Rudy Birsen, Teresa Bernal Del Castillo, Emmanuelle Tavernier, Mar Tormo, Martin Carre, Maria Jose Garcia, Adrien Contejean, Rosalia Riaza Grau, Corentin Orvain, Jose Antonio Pérez-Simón, Esther Perez Santaolla, Lauren Veronese, Beatriz De Rueda Ciller, Eric Delabesse, Antonio Gutiérrez, Ariane Mineur, Adolfo De La Fuente Burguera, Romain Guieze, Arnaud Pigneux, Pau Montesinos, Christian Recher, David Matínez-Cuadrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 2864.
https://doi.org/10.1182/blood-2023-190128
Published: 2023
Journal Articles

Current Results of Intensive Therapy in Younger Adults with Acute Myeloid Leukemia (AML): The Large Randomized French Backbone Intergroup (BIG)-1 Study on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Hunault-Berger Mathilde, Cécile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Tony Marchand, Marie Anne Hospital, Mael Heiblig, Sylvain Chantepie, Martin Carré, Pierre Peterlin, Emilie Lemasle, Célestine Simand, Maria Pilar Gallego Hernanz, Anne Huynh, Edouard Forcade, Raynier Devillier, Stéphanie Nguyen Quoc, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Gerard Socié, Jean-Yves Cahn, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Arnaud Pigneux, Christian Recher, Hervé Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 967.
https://doi.org/10.1182/blood-2023-179376
Published: 2023
Journal Articles

Hyperleukocytosis Increases the Risk of Early Relapses Independently of Genetics in AML

Raphaël Liévin, Nicolas Duployez, Loïc Vasseur, Juliette Lambert, Mael Heiblig, Mathilde Hunault, Claude Gardin, Stephane De Botton, Elise Fournier, Cecile Pautas, Christine Terré, Eric Delabesse, Norbert Ifrah, Arnaud Pigneux, Celli-Lebras Karine, Christian Recher, Claude Preudhomme, Herve Dombret, Raphael Itzykson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4322.
https://doi.org/10.1182/blood-2023-173614
Published: 2023
Journal Articles

Molecular Relapse after First-Line Intensive Therapy in Patients with Core-Binding Factor and NPM1 -Mutated Acute Myeloid Leukemia - a Filo Study

Corentin Orvain, Sarah Bertoli, Pierre Peterlin, Yohan Desbrosses, Pierre-Yves Dumas, Alexandre Iat, Marie Anne Hospital, Martin Carre, Emmanuelle Tavernier, Anne Bouvier, Audrey Bidet, Sylvie Tondeur, Florian Renosi, Eric Delabesse, Arnaud Pigneux, Hunault-Berger Mathilde, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 421.
https://doi.org/10.1182/blood-2023-184848
Published: 2023
Journal Articles

A First-in-Human Phase 1 Study of the Menin-KMT2A (MLL1) Inhibitor JNJ-75276617 in Adult Patients with Relapsed/Refractory Acute Leukemia Harboring KMT2A or NPM1 Alterations

Elias Jabbour, Emma Searle, Maher Abdul-Hay, Sameem Abedin, Ibrahim Aldoss, Ana Alfonso Piérola, Juan Manuel Alonso-Dominguez, Patrice Chevallier, Carrye Cost, Nikki Daskalakis, Richard Dillon, Neil Dunavin, Jordi Esteve, Amir T. Fathi, Pasquale L. Fedele, Lucille Ferrante, Sylvain Garciaz, Christina Guttke, Emmanuel Gyan, Brett Hiebert, Min Chul Kwon, Jonathan Miller, Teng Fong Ng, Kathryn Packman, Ulrike Philippar, Arnaud Pigneux, Christian Recher, Olga Salamero, Madhu Sanga, Richard M Stone, Peter Tan, Jan Willem Thuring, Trevor Tucker, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 57.
https://doi.org/10.1182/blood-2023-172422
Published: 2023
Journal Articles

Venetoclax in Combination with Intermediate Doses of Cytarabine in Consolidation Phase for Acute Myeloid Leukemia Patients in First Complete Remission; Results of the Part 1 of the Phase 1/2 Multicentric Covenidac Study

Lauris Gastaud, Pierre Peterlin, Mathilde Hunault, Emmanuel Raffoux, Sarah Bertoli, Martin Carré, Cecile Pautas, Sylvain Chantepie, Juliette Lambert, Nicolas Duployez, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Vey, Arnaud Pigneux, Eric Delabesse, Claude Preudhomme, Adriana Plesa, Francois Vergez, Jean-François Hamel, Herve Dombret, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2023-173656
Published: 2023
Journal Articles

Levofloxacin to Prevent Bacterial Infection in Patients with Acute Myeloid Leukemia Treated By Azacitidine and Venetoclax: A Study from the Dataml Registry

Xavier Brousse, Nicolas Rasandisona, Harmony Leroy, Karen Delavigne, Nathan Mottal, Suzanne Tavitian, Thibaut Leguay, Leopoldine Lapierre, Eric Delabesse, Audrey Bidet, Martin Gauthier, Diane Lara, Claire Calmettes, Audrey Sarry, Noemie Gadaud, Benoit Branco, anne-Charlotte de Grande, Clementine Beranger, Christian Recher, Arnaud Pigneux, Sarah Bertoli, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 7443.
https://doi.org/10.1182/blood-2023-182117
Published: 2023
Journal Articles

CPX-351 in Patients with Newly Diagnosed Post Myeloproliferative Neoplasms Acute Myeloid Leukemia

Sylvain Garciaz, Amine Belhabri, Romain Guieze, Laure Goursaud, Pierre Peterlin, Marie-Pierre Ledoux, Hunault-Berger Mathilde, Safia Chebrek, Jean-Baptiste Robin, Arnaud Pigneux, Sarah Bonnet, Caroline Bonmati, Sarah Bertoli, Thorsten Braun, Sylvain Chantepie, Mathieu Meunier, Mael Heiblig, Thomas Cluzeau, Eric Jourdan, Alban Villate, Christian Recher, Norbert Vey, Jerome Rey
Journal: Blood
Blood (2023) 142 (Supplement 1): 2917.
https://doi.org/10.1182/blood-2023-184591
Published: 2023
Journal Articles

Association between Molecular Profile and Outcome after Intensive Chemotherapy in Patients > 60 Years with Adverse Cytogenetic Risk and/or Secondary Acute Myeloid Leukemia - a Filo Study

Corentin Orvain, Anne Bouvier, Audrey Bidet, Pierre-Yves Dumas, Sarah Bertoli, Odile Blanchet, Sylvain Thepot, Aline Schmidt, Arnaud Pigneux, Eric Delabesse, Christian Recher, Hunault-Berger Mathilde
Journal: Blood
Blood (2023) 142 (Supplement 1): 2851.
https://doi.org/10.1182/blood-2023-184815
Published: 2023
Journal Articles

Venetoclax and Azacitidine for Molecular Relapse during First Line Intensive Chemotherapy in Patients with NPM1 Mutated or Core Binding Factor (CBF) AML. a Study from the Dataml Registry

Jules Higué, Pierre-Yves Dumas, Laetitia Largeaud, Audrey Bidet, Émilie Klein, Olivier Mansier, Lucie Rigolot, Eric Delabesse, Anne Banos, Suzanne Tavitian, Thibaut Leguay, Sarah Guenounou, Edouard Forcade, Sarah Bertoli, Arnaud Pigneux, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 2887.
https://doi.org/10.1182/blood-2023-180773
Published: 2023
Journal Articles

Clonal Dynamics of FLT3 -ITD Positive Acute Myeloid Leukemia Patients with Relapsed/Refractory Disease Following Intensive Chemotherapy +/- Midostaurin

Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Herve Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Lamya Haddaoui, Raphael Itzykson, Christian Recher, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 976.
https://doi.org/10.1182/blood-2023-182018
Published: 2023
Journal Articles

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Manja Meggendorfer, Enrico Tiacci, Christian Thiede, Richard Schlenk, Richard Dillon, Sebastian Stasik, Alessandra Venanzi, Sarah Bertoli, Eric Delabesse, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Amanda F. Gilkes, Ian Thomas, Maria Teresa Voso, Alessandro Rambaldi, Lorenzo Brunetti, Vincenzo M. Perriello, Vibeke Andresen, Bjorn T. Gjertsen, Maria Paola Martelli, Christian Récher, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Carsten Müller-Tidow, Claudia D. Baldus, Tortsten Haferlach, Nigel Russell, Brunangelo Falini
Journal: Blood
Blood (2023) 141 (15): 1846–1857.
https://doi.org/10.1182/blood.2022018108
Published: 2023
Includes: Supplemental data
Journal Articles

Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial

Clinical Trials & Observations
Naval G. Daver, Monique Dail, Jacqueline S. Garcia, Brian A. Jonas, Karen W. L. Yee, Kevin R. Kelly, Norbert Vey, Sarit Assouline, Gail J. Roboz, Stefania Paolini, Daniel A. Pollyea, Agostino Tafuri, Joseph M. Brandwein, Arnaud Pigneux, Bayard L. Powell, Pierre Fenaux, Rebecca L. Olin, Giuseppe Visani, Giovanni Martinelli, Maika Onishi, Jue Wang, Weize Huang, Cherie Green, Marion G. Ott, Wan-Jen Hong, Marina Y. Konopleva, Michael Andreeff
Journal: Blood
Blood (2023) 141 (11): 1265–1276.
https://doi.org/10.1182/blood.2022016362
Published: 2023
Includes: Supplemental data
Journal Articles

Enasidenib vs conventional care in older patients with late-stage mutant- IDH2 relapsed/refractory AML: a randomized phase 3 trial

Clinical Trials & Observations
Stéphane de Botton, Pau Montesinos, Andre C. Schuh, Cristina Papayannidis, Paresh Vyas, Andrew H. Wei, Hans Ommen, Sergey Semochkin, Hee-Je Kim, Richard A. Larson, Jaime Koprivnikar, Olga Frankfurt, Felicitas Thol, Jörg Chromik, Jenny Byrne, Arnaud Pigneux, Xavier Thomas, Olga Salamero, Maria Belen Vidriales, Vadim Doronin, Hartmut Döhner, Amir T. Fathi, Eric Laille, Xin Yu, Maroof Hasan, Patricia Martin-Regueira, Courtney D. DiNardo
Journal: Blood
Blood (2023) 141 (2): 156–167.
https://doi.org/10.1182/blood.2021014901
Published: 2023
Includes: Supplemental data
Journal Articles

Dexaml-02 : A Phase II Study of Dexamethasone Added to Induction and Postremission Therapy in Older Patients with Newly Diagnosed AML. a French Innovative Leukemia Organization (FILO) Study

Christian Recher, Sarah Bertoli, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Yosr Hicheri, Omar Benbrahim, Martin Carre, Hunault-Berger Mathilde, Anne Banos, Marc Bernard, Emmanuel Gyan, Alain Saad, Safia Chebrek, Gabrielle Roth Guepin, Veronique Dorvaux, Laurence Sanhes, Maria Pilar Gallego Hernanz, Carole Exbrayat, Laure Vincent, Chantal Himberlin, Laetitia Largeaud, Eric Delabesse, Francois Vergez, Norbert Vey, Ariane C Mineur, Célestine Simand, Isabelle Luquet, Arnaud Pigneux
Journal: Blood
Blood (2022) 140 (Supplement 1): 6149–6151.
https://doi.org/10.1182/blood-2022-158665
Published: 2022