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Journal Articles

Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemia: Topline Efficacy and Safety Results from the Pivotal Augment-101 Phase 2 Study

Ibrahim Aldoss, Ghayas C. Issa, Michael Thirman, John DiPersio, Martha Arellano, James S. Blachly, Gabriel N. Mannis, Alexander Perl, David S. Dickens, Christine M. McMahon, Elie Traer, C. Michel Zwaan, Carolyn Grove, Richard Stone, Paul J. Shami, Ioannis Mantzaris, Matthew Greenwood, Neerav Shukla, Branko Cuglievan, Yu Gu, Rebecca G. Bagley, Kate Madigan, Soujanya Sunkaraneni, Huy Van Nguyen, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-5.
https://doi.org/10.1182/blood-2023-192042
Published: 2023
Journal Articles

Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemias: Efficacy and Safety Results from the Augment-101 Phase 1/2 Study

Ibrahim Aldoss, Ghayas C. Issa, Michael J Thirman, John DiPersio, Martha Arellano, James S. Blachly, Gabriel Mannis, Alexander Perl, David Dickens, Christine M. McMahon, Elie Traer, C. Michel Zwaan, Carolyn Grove, Richard Stone, Paul J Shami, Ioannis Mantzaris, Matthew Greenwood, Neerav Shukla, Branko Cuglievan, Yu Gu, Rebecca G Bagley, Kate Madigan, Soujanya Sunkaraneni, Huy Van Nguyen, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2907.
https://doi.org/10.1182/blood-2023-189762
Published: 2023
Journal Articles

Genomic Profiles and Associated Survival Prognosticators in Black Patients with Acute Myeloid Leukemia

Andrew Stiff, Deedra Nicolet, Maarten Fornerod, Ben Kelly, Katherine Miller, Krzysztof Mrózek, Isaiah Boateng, Bailee Nicole Kain, Elizabeth Garfinkle, Eileen Y Hu, Saranga Wijeratne, Gregory Wheeler, Christopher J. Walker, Jill Buss, Adrienne Heyrosa, Helee Desai, Andrea Laganson, Yazan Abu-Shihab, Hasan Abaza, Alice Mims, Christopher C. Oakes, Bethany L Mundy-Bosse, Andrew J Carroll, Bayard L Powell, Jonathan E Kolitz, Richard Stone, Electra D Paskett, Ross L Levine, Kamal Menghrajani, Debyani Chakravarty, Michael F. Berger, Nathan Salomonis, Daniel Bottomly, Shannon K McWeeney, Jeffrey W Tyner, John C. Byrd, H. Leighton Grimes, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 837.
https://doi.org/10.1182/blood-2023-181876
Published: 2023
Journal Articles

Phase 1 Trial of Dendritic Cell/AML Fusion Cell Vaccine after Allogeneic Stem Cell Transplant in Acute Myeloid Leukemia

Jessica Liegel, Giulia Cheloni, Georges Chedid, Genevieve Gerhard, Dimitra Karagkouni, Richard Stone, Robert J. Soiffer, Lina Bisharat, Samprity Ankita, Isabella Saldarriaga, Emma K Logan, Michele Narcis, Jennifer Tichon, Yiwen Liu, Malgorzata McMasters, Juan Carlos Varela, Hassan El Banna, Vincent T. Ho, Rizwan Romee, Donna S. Neuberg, Kathrine S Rallis, Sophia Adamia, Benjamin L. Ebert, Donald Kufe, Ioannis Vlachos, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 772.
https://doi.org/10.1182/blood-2023-190832
Published: 2023
Journal Articles

A Phase 2 Study of Lenalidomide in Combination with Mitoxantrone, Etoposide, and Cytarabine (Len plus MEC) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Manik Razdan Kuchroo, Robert A. Redd, Jacqueline S. Garcia, Michael Keng, Gabriela S. Hobbs, Jacalyn Rosenblatt, Marlise R. Luskin, Rupa Narayan, Philip C. Amrein, Malgorzata McMasters, Martha Wadleigh, Hanno Hock, Richard Stone, Donna S. Neuberg, David Avigan, Karen K. Ballen, Amir T. Fathi, Daniel J. DeAngelo, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2023-188182
Published: 2023
Journal Articles

Measurable residual disease does not preclude prolonged progression-free survival in CLL treated with ibrutinib

Clinical Trials & Observations
Xin Victoria Wang, Curtis A. Hanson, Renee C. Tschumper, Connie E. Lesnick, Esteban Braggio, Elisabeth M. Paietta, Susan O’Brien, Jacqueline C. Barrientos, Jose Francisco Leis, Cong Christine Zhang, Steven E. Coutre, Paul M. Barr, Amanda F. Cashen, Anthony R. Mato, Avina K. Singh, Michael P. Mullane, Harry Erba, Richard Stone, Mark R. Litzow, Martin S. Tallman, Tait D. Shanafelt, Neil E. Kay
Journal: Blood
Blood (2021) 138 (26): 2810–2827.
https://doi.org/10.1182/blood.2020010146
Published: 2021
Includes: Supplemental data
Journal Articles

Next-Generation RNA Sequencing-Based Analysis Identifies a Novel Set of Prognostic Micrornas (miRs) in Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Dimitrios Papaioannou, MD, Deedra Nicolet, MS, Kellie J Archer, PhD, Allison Walker, Krzysztof Mrózek, MD PhD, Andrew J. Carroll, PhD, Jessica Kohlschmidt, PhD, Ann-Kathrin Eisfeld, MD, Marius Bill, MD PhD, Christopher J. Walker, PhD, Geoffrey L. Uy, MD, Bayard L Powell, MD, Jonathan E. Kolitz, MD, Richard Stone, MD, John C. Byrd, MD, Ramiro Garzon, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2694.
https://doi.org/10.1182/blood-2019-125727
Published: 2019
Journal Articles

Sleep Disturbance Among Patients with Myelodysplastic Syndromes and Acute Leukemia

Marlise Luskin, MDMS, Eric Zhou, PhD, Zilu Zhang, MS, Daniel J. DeAngelo, MD PhD, Richard Stone, MD, Martha Wadleigh, MD, Jacqueline S Garcia, MD, Eric S. Winer, MD, Christopher Recklitis, PhD, Kelsey O'Day, Victoria Lapiana, Ryan Osborn, David P. Steensma, MD, Gregory A. Abel, MDMPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4786.
https://doi.org/10.1182/blood-2019-125147
Published: 2019
Journal Articles

A Phase I Study of Asciminib (ABL001) in Combination with Dasatinib and Prednisone for Untreated BCR-ABL1-Positive ALL in Older Adults

Marlise Luskin, MDMS, Mark A. Murakami, MDMA,MMSc, Kristen E. Stevenson, MS, Martha Wadleigh, MD, Malgorzata McMasters, MD, Peter Winter, PhD, David M. Weinstock, MD, Richard Stone, MD, Daniel J. DeAngelo, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3879.
https://doi.org/10.1182/blood-2019-125138
Published: 2019
Journal Articles

Distinct Gene Expression Profiles and Mutations Associate with Outcome in Younger Adults with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (Alliance)

Christopher J. Walker, PhD, Ann-Kathrin Eisfeld, MD, Hatice G Ozer, PhD, Jessica Kohlschmidt, PhD, Deedra Nicolet, Krzysztof Mrózek, MD PhD, Dimitrios Papaioannou, MD, Luke K Genutis, BS, Bayard L Powell, MD, Geoffrey L. Uy, MD, Jonathan E. Kolitz, MD, Andrew J. Carroll, PhD, Richard Stone, MD, Ramiro Garzon, MD, John C. Byrd, MD, Albert de la Chapelle, MD PhD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1247.
https://doi.org/10.1182/blood-2019-127478
Published: 2019
Journal Articles

Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma

Clinical Trials & Observations
John Kuruvilla, Michael Savona, Rachid Baz, Paul Morten Mau-Sorensen, Nashat Gabrail, Ramiro Garzon, Richard Stone, Michael Wang, Lynn Savoie, Peter Martin, Ian Flinn, Meagan Jacoby, Thaddeus J. Unger, Jean-Richard Saint-Martin, Tami Rashal, Sharon Friedlander, Robert Carlson, Michael Kauffman, Sharon Shacham, Martin Gutierrez
Journal: Blood
Blood (2017) 129 (24): 3175–3183.
https://doi.org/10.1182/blood-2016-11-750174
Published: 2017
Includes: Supplemental data
Journal Articles

A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia

Clinical Trials & Observations
Ramiro Garzon, Michael Savona, Rachid Baz, Michael Andreeff, Nashat Gabrail, Martin Gutierrez, Lynn Savoie, Paul Morten Mau-Sorensen, Nina Wagner-Johnston, Karen Yee, Thaddeus J. Unger, Jean-Richard Saint-Martin, Robert Carlson, Tami Rashal, Trinayan Kashyap, Boris Klebanov, Sharon Shacham, Michael Kauffman, Richard Stone
Journal: Blood
Blood (2017) 129 (24): 3165–3174.
https://doi.org/10.1182/blood-2016-11-750158
Published: 2017
Includes: Supplemental data
Journal Articles

Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era

Clinical Trials & Observations
Simon Mantha, Debra A. Goldman, Sean M. Devlin, Ju-Whei Lee, Diana Zannino, Marnie Collins, Dan Douer, Harry J. Iland, Mark R. Litzow, Eytan M. Stein, Frederick R. Appelbaum, Richard A. Larson, Richard Stone, Bayard L. Powell, Susan Geyer, Kristina Laumann, Jacob M. Rowe, Harry Erba, Steven Coutre, Megan Othus, Jae H. Park, Peter H. Wiernik, Martin S. Tallman
Journal: Blood
Blood (2017) 129 (13): 1763–1767.
https://doi.org/10.1182/blood-2016-10-747170
Published: 2017
Journal Articles

MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells

Suiyang Liu, Li Yin, Dina Stroopinsky, Hasan Rajabi, Alexandre Puissant, Kimberly Stegmaier, David Avigan, Surender Kharbanda, Donald Kufe, Richard Stone
Journal: Blood
Blood (2014) 123 (5): 734–742.
https://doi.org/10.1182/blood-2013-04-493858
Published: 2014
Includes: Supplemental data
Journal Articles

Measuring Mitochondrial Apoptotic Priming by BH3 Profiling Predicts Induction Outcome for Acute Myeloid Leukemia Patients

Thanh-Trang T Vo, MD, Richard Stone, MD, Daniel J DeAngelo, MD, PhD, Mark G. Frattini, MD, PhD, Anthony G. Letai, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 239.
https://doi.org/10.1182/blood.V118.21.239.239
Published: 2011
Journal Articles

SAR302503: Interim Safety, Efficacy and Long-Term Impact on JAK2 V617F Allele Burden in a Phase I/II Study in Patients with Myelofibrosis,

Animesh Pardanani, MBBS, PhD, Jason Gotlib, M.D., M.S., Catriona Jamieson, Jorge E. Cortes, Moshe Talpaz, Richard Stone, MD, Guozhi Gao, Jenny (Yanzhen) Zhang, MD, PhD, Frank Neumann, MD, PhD, Ayalew Tefferi, MD
Journal: Blood
Blood (2011) 118 (21): 3838.
https://doi.org/10.1182/blood.V118.21.3838.3838
Published: 2011
Journal Articles

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

Elspeth M. Payne, Niccolò Bolli, Jennifer Rhodes, Omar I. Abdel-Wahab, Ross Levine, Cyrus V. Hedvat, Richard Stone, Arati Khanna-Gupta, Hong Sun, John P. Kanki, Hanna T. Gazda, Alan H. Beggs, Finbarr E. Cotter, A. Thomas Look
Journal: Blood
Blood (2011) 118 (4): 903–915.
https://doi.org/10.1182/blood-2010-11-318022
Published: 2011
Includes: Multimedia, Supplemental data
Journal Articles

MUC1-C oncoprotein suppresses reactive oxygen species–induced terminal differentiation of acute myelogenous leukemia cells

Li Yin, Zekui Wu, David Avigan, Jacalyn Rosenblatt, Richard Stone, Surender Kharbanda, Donald Kufe
Journal: Blood
Blood (2011) 117 (18): 4863–4870.
https://doi.org/10.1182/blood-2010-10-296632
Published: 2011
Includes: Supplemental data
Journal Articles

Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse

Clinical Trials & Observations
Mark Levis, Farhad Ravandi, Eunice S. Wang, Maria R. Baer, Alexander Perl, Steven Coutre, Harry Erba, Robert K. Stuart, Michele Baccarani, Larry D. Cripe, Martin S. Tallman, Giovanna Meloni, Lucy A. Godley, Amelia A. Langston, Sergio Amadori, Ian D. Lewis, Arnon Nagler, Richard Stone, Karen Yee, Anjali Advani, Dan Douer, W. Wiktor-Jedrzejczak, Gunnar Juliusson, Mark R. Litzow, Stephen Petersdorf, Miguel Sanz, Hagop M. Kantarjian, Takashi Sato, Lothar Tremmel, Debra M. Bensen-Kennedy, Donald Small, B. Douglas Smith
Journal: Blood
Blood (2011) 117 (12): 3294–3301.
https://doi.org/10.1182/blood-2010-08-301796
Published: 2011
Journal Articles

Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition

Dina Stroopinsky, PhD, Jacalyn Rosenblatt, MD, MSc, Keisuke Ito, MD, PhD, Li Yin, Hasan Rajabi, PhD, Baldev Vasir, PhD, Turner Kufe, Brett Glotzbecker, MD, Katarina Luptakova, MD, Heidi Mills, BA, Robin Joyce, MD, Dimitrios Tzachanis, MD, PhD, Vassiliki A Boussiotis, MD, PhD, James Levine, MD, Ilene Galinsky, ANP, Richard Stone, MD, Pier Paolo Pandolfi, MD, PhD, Donald Kufe, MD, David Avigan, MD
Journal: Blood
Blood (2010) 116 (21): 848.
https://doi.org/10.1182/blood.V116.21.848.848
Published: 2010