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Journal Articles

Acute Lymphoblastic Leukemia (ALL) Outcomes after Allogeneic Blood or Marrow Transplantation (alloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) in the Era of More Effective Pre-Transplant Therapy

Jonathan Allen Webster, Madison C Reed, Hua-Ling Tsai, Philip Imus, B. Douglas Smith, Alexander J. Ambinder, Mark J. Levis, Amy E. DeZern, Gabrielle T. Prince, Javier Bolanos-Meade, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Theodoros Karantanos, Suman Paul, Ephraim Joseph Fuchs, Cole Sterling, Lode J. Swinnen, Nina Wagner-Johnston, Richard F. Ambinder, Christian B. Gocke, Syed Abbas Ali, Carol Ann Huff, Leo Luznik, Ravi Varadhan, Richard J. Jones, Ivana Gojo
Journal: Blood
Blood (2024) 144 (Supplement 1): 3551.
https://doi.org/10.1182/blood-2024-212141
Published: 2024
Journal Articles

Efficacy and Tolerability of Blinatumomab in Clinical Trial Ineligible Patients with CD19+ Leukemias

John Preston Claiborne, Daniel Li, B. Douglas Smith, Mark J. Levis, Ivana Gojo, Amy E. DeZern, Alexander J. Ambinder, Tania Jain, Gabrielle T. Prince, Lukasz P. Gondek, Theodoros Karantanos, Gabriel Ghiaur, William Brian Dalton, Jonathan Allen Webster
Journal: Blood
Blood (2024) 144 (Supplement 1): 5904.
https://doi.org/10.1182/blood-2024-207608
Published: 2024
Journal Articles

Efficacy and Safety of Pembrolizumab Added to Azacitidine Plus Venetoclax for Patients with Acute Myeloid Leukemia: Results from an Investigator-Initiated, Multi-Center, CTEP-Sponsored Randomized, Phase II Trial (BLAST AML-2)

Jessica M. Stempel, Geoffrey L. Uy, Shira N. Dinner, Ivana Gojo, Daniel Reed, Rupali Roy, Kenneth P Byrd, Swaroopa Yerrabothala, Catherine E. Lai, Kimberley Doucette, Anne Caldwell, Ondrej Blaha, Nikolai A. Podoltsev, Lourdes M Mendez, Jan Philipp Bewersdorf, Tariq Kewan, Ignacio Wistuba, Gheath Alatrash, Cara L Haymaker, Howard Streicher, Elad Sharon, Richard Little, Steven D. Gore, Jerald P. Radich, Brent L. Wood, Amer M. Zeidan, Rory M. Shallis
Journal: Blood
Blood (2024) 144 (Supplement 1): 736.
https://doi.org/10.1182/blood-2024-210370
Published: 2024
Journal Articles

CD8 + T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia

Francesco Mazziotta, Luca Biavati, Joseph Rimando, Sergio Rutella, Nicholas Borcherding, Sonali Parbhoo, Rupkatha Mukhopadhyay, Sayan Chowdhury, Hanna A. Knaus, Peter Valent, Hubert Hackl, Ivan M. Borrello, Bruce R. Blazar, Katerina Hatzi, Ivana Gojo, Leo Luznik
Journal: Blood
Blood (2024) 144 (11): 1168–1182.
https://doi.org/10.1182/blood.2023021680
Published: 2024
Includes: Supplemental data
Journal Articles

A Phase IB/II Study of Blinatumomab in Patients with B-Cell Acute Lymphoblastic Leukemia (ALL) and B-Cell Non-Hodgkin Lymphoma (NHL) As Post-Allogeneic Blood or Marrow Transplant (alloBMT) Remission Maintenance

Jonathan Allen Webster, Richard J. Jones, Amanda Blackford, Audra Shedeck, Richard F. Ambinder, Lode J. Swinnen, Nina Wagner-Johnston, Ephraim Joseph Fuchs, Javier Bolanos-Meade, Philip Imus, Challice L. Bonifant, Heather Jill Symons, Tania Jain, Gabrielle T. Prince, Mark J. Levis, Leo Luznik, Ivana Gojo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3582.
https://doi.org/10.1182/blood-2023-191047
Published: 2023
Journal Articles

A Phase I Trial of Activated Donor-Derived Marrow Infiltrating Lymphocytes to Treat Relapsed Hematologic Malignancies after Allogeneic Transplantation with Post-Transplantation Cyclophosphamide As Graft-Versus-Host Disease Prophylaxis

Joseph Rimando, Francesco Mazziotta, Alison Gareau, Maria Bettinotti, Jonathan Allen Webster, Syed Abbas Ali, Philip Imus, Mario Victor Lemas, Amy E. DeZern, Mark J. Levis, Marianna Zahurak, Ravi Varadhan, Richard F. Ambinder, Carol Huff, Ivana Gojo, Richard J. Jones, Ivan M. Borrello, Leo Luznik
Journal: Blood
Blood (2023) 142 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2023-179394
Published: 2023
Journal Articles

Blinatumomab in Combination with Immune Checkpoint Inhibitors (ICIs) of PD-1 and CTLA-4 in Adult Patients with Relapsed/Refractory (R/R) CD19 Positive B-Cell Acute Lymphoblastic Leukemia (ALL): Results of a Phase I Study

Jonathan Allen Webster, Marlise R. Luskin, Joseph Rimando, Amanda Blackford, Amer M. Zeidan, Elad Sharon, Howard Streicher, Daniel J. DeAngelo, Leo Luznik, Ivana Gojo
Journal: Blood
Blood (2023) 142 (Supplement 1): 966.
https://doi.org/10.1182/blood-2023-191109
Published: 2023
Journal Articles

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Journal: Blood
Blood (2023) 141 (6): 567–578.
https://doi.org/10.1182/blood.2022017865
Published: 2023
Journal Articles

Different Subsets of Exhausted and Senescent-like T Cells Correlate with Response and Survival in Patients with Acute Myeloid Leukemia (AML) Undergoing Chemotherapy

Francesco Mazziotta, Luca Biavati, Sonali Parbhoo, Sayan Chowdhury, Joseph Rimando, Ivan M. Borrello, Katerina Hatzi, Bruce R. Blazar, Ivana Gojo, Leo Luznik
Journal: Blood
Blood (2022) 140 (Supplement 1): 9132–9133.
https://doi.org/10.1182/blood-2022-167107
Published: 2022
Journal Articles

Phase II Study of Tagraxofusp in Newly Diagnosed Secondary Acute Myeloid Leukemia (S-AML) after Previous Exposure to Hypomethylating Agents (TAGALONG Study)

Steven D. Green, Brian Parkin, Catherine Lai, Ivana Gojo, Matthew C. Foster, Joshua F. Zeidner
Journal: Blood
Blood (2022) 140 (Supplement 1): 11749–11750.
https://doi.org/10.1182/blood-2022-170738
Published: 2022
Journal Articles

Gemtuzumab Ozogamicin for Cytoreduction in Hyperleukocytosis

Matthew Scarlotta, Jonathan Webster, Matthew Newman, Cory Schulz, Kristin Stokvis, Alexander J. Ambinder, Tania Jain, William Brian Dalton, Lukasz P. Gondek, Gabrielle T. Prince, Gabriel Ghiaur, Christopher S. Hourigan, Amy E. DeZern, Ivana Gojo, Jonathan Allen Webster, Mark J. Levis
Journal: Blood
Blood (2022) 140 (Supplement 1): 11747–11748.
https://doi.org/10.1182/blood-2022-160300
Published: 2022
Journal Articles

Outcomes of Patients with TP53 -Mutated Myeloid Neoplasms (TP53-MN) and the Role of Allogenic Blood or Marrow Transplantation (alloBMT)

Sergiu Pasca, Saurav D. Haldar, Alexander J. Ambinder, Jonathan Webster, Tania Jain, William Brian Dalton, Gabrielle T. Prince, Gabriel Ghiaur, Amy E. DeZern, Ivana Gojo, Jonathan Allen Webster, Cory Schulz, Kristin Stokvis, Mark J. Levis, Richard J. Jones, Lukasz P. Gondek
Journal: Blood
Blood (2022) 140 (Supplement 1): 10629–10631.
https://doi.org/10.1182/blood-2022-169148
Published: 2022
Journal Articles

Allogeneic Blood or Marrow Transplantation (AlloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) for Acute Lymphoblastic Leukemia (ALL) in Patients Aged ≥ 55: Best Results in B ALL in First Remission (CR1) with Reduced-Intensity Conditioning (RIC)

Jonathan Allen Webster, Madison C. Reed, Hua-Ling Tsai, Alexander J. Ambinder, Tania Jain, Amy E. DeZern, Mark J. Levis, Margaret M. Showel, Gabrielle T. Prince, Christopher S. Hourigan, Javier Bolaños-Meade, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Suman Paul, Ephraim J. Fuchs, Christian B. Gocke, Abbas Abbas Ali, Douglas E. Gladstone, Carol Ann Huff, Ivan M. Borrello, Lode J. Swinnen, Nina D. Wagner-Johnston, Richard F. Ambinder, Leo Luznik, Ivana Gojo, B. Douglas Douglas Smith, Ravi Varadhan, Richard J. Jones, Philip H. Imus
Journal: Blood
Blood (2022) 140 (Supplement 1): 4813–4815.
https://doi.org/10.1182/blood-2022-171038
Published: 2022
Journal Articles

The Composition of Acute Myeloid Leukemia Cell Differentiation States Predicts Response to Immune Checkpoint Blockade

Joseph Rimando, Leslie Cope, Karen McKinnon, Benjamin G. Vincent, Sergio Rutella, Joshua F. Zeidner, Jonathan S. Serody, Ivana Gojo, Leo Luznik
Journal: Blood
Blood (2022) 140 (Supplement 1): 6314–6315.
https://doi.org/10.1182/blood-2022-165458
Published: 2022
Journal Articles

Transcriptomic Features of Immune Exhaustion and Senescence Predict Outcomes and Define Checkpoint Blockade-Unresponsive Microenvironments in Acute Myeloid Leukemia

Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung On Yau, Rupkatha Mukhopadhyay, Heidi Altmann, Michael Kramer, Hanna A. Knaus, Joshua F. Zeidner, Vedran Radojcic, Andrea Arruda, Mark D. Minden, Sarah K Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik
Journal: Blood
Blood (2021) 138 (Supplement 1): 223.
https://doi.org/10.1182/blood-2021-145854
Published: 2021
Journal Articles

Bone Marrow GZMK + IL7R + Progenitor-Exhausted CD8 + T Cells Correlate with Sustained Clinical Remission in Patients with Acute Myeloid Leukemia (AML) Undergoing Chemotherapy

Francesco Mazziotta, Luca Biavati, Rupkatha Mukhopadhyay, Hanna A. Knaus, Ivan M. Borrello, Ivana Gojo, Leo Luznik
Journal: Blood
Blood (2021) 138 (Supplement 1): 521.
https://doi.org/10.1182/blood-2021-149150
Published: 2021
Journal Articles

Nonmyeloablative Allogeneic Transplantation in First Remission for Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Outcomes By Receipt of Pre-Transplant Blinatumomab

Jonathan Webster, B. Douglas Smith, Amy E. DeZern, Alexander J. Ambinder, Mark Levis, Margaret M. Showel, Gabrielle T. Prince, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Christopher S. Hourigan, Tania Jain, Douglas E Gladstone, Leo Luznik, Philip H. Imus, Javier Bolanos-Meade, Ephraim J. Fuchs, Christian B. Gocke, Abbas Abbas Ali, Carol Ann Huff, Ivan M. Borrello, Lode J. Swinnen, Nina D. Wagner-Johnston, Richard F. Ambinder, Richard J. Jones, Ivana Gojo
Journal: Blood
Blood (2021) 138 (Supplement 1): 1846.
https://doi.org/10.1182/blood-2021-153750
Published: 2021
Journal Articles

An Immune Senescence and Exhaustion-Related RNA Profile Predicts Clinical Outcomes in Acute Myeloid Leukemia

Jayakumar Vadakekolathu, PhD, Tung On Yau, Heidi Altmann, PhD, Sarah E. Church, PhD, Hanna A Knaus, MD, Mark D. Minden, Jan K Davidson-Moncada, MDPhD, Sarah K Tasian, MD, Martin Bornhäuser, MD, Ivana Gojo, MD, Leo Luznik, MD, Sergio Rutella, MDPhDFRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-134779
Published: 2020
Journal Articles

Allogeneic Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Assessing the Importance of Conditioning Regimen, Donor Choice, and Tyrosine Kinase Inhibitor Use

Jonathan Webster, MD, Leo Luznik, MD, Hua-Ling Tsai, ScM, Philip H. Imus, MD, Amy E. DeZern, MD, Keith W. Pratz, MD, Mark Levis, MD PhD, Ivana Gojo, MD, Margaret M. Showel, MD, Gabrielle T. Prince, MD, Javier Bolanos-Meade, MD, Lukasz P. Gondek, MDPhD, Gabriel Ghiaur, MD PhD, William Brian Dalton, MD PhD, Tania Jain, MD, Ephraim J. Fuchs, MD MBA, Douglas E Gladstone, MD, Christian B. Gocke, MD PhD, Abbas Abbas Ali, MD, Carol Ann Huff, MD, Ivan M. Borrello, MD, Lode J. Swinnen, MB ChB, Nina D. Wagner-Johnston, Richard F. Ambinder, MD, Richard J. Jones, MD, B. Douglas Smith, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-141294
Published: 2020
Journal Articles

Reduced-Intensity Induction with Dasatinib Vs. Hypercvad + 2 nd Generation TKIs with MRD-Guided Follow-up Therapy Leads to Comparable Rates of MRD-Negative Remission While Reducing Transfusions and Neutropenia in Ph+ ALL

Jonathan Webster, MD, Hua-Ling Tsai, ScM, Eric Gehrie, Tania Jain, MD, Christopher S. Hourigan, MDDPhil, William Brian Dalton, MD PhD, Gabrielle T. Prince, MD, Lukasz P. Gondek, MDPhD, Gabriel Ghiaur, MD PhD, Amy E. DeZern, MD, Margaret M. Showel, MD, Ivana Gojo, MD, Douglas E Gladstone, MD, Philip H. Imus, MD, Javier Bolanos-Meade, MD, Leo Luznik, MD, Ephraim J. Fuchs, MD MBA, Christian B. Gocke, MD PhD, Abbas Abbas Ali, MD, Carol Ann Huff, MD, Ivan M. Borrello, MD, Lode J. Swinnen, MB ChB, Nina D. Wagner-Johnston, Richard F. Ambinder, MD, Richard J. Jones, MD, B. Douglas Smith, MD, Mark Levis, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-141264
Published: 2020