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Journal Articles

CD8+ T-cell Differentiation and Dysfunction Inform Treatment Response in Acute Myeloid Leukemia

Francesco Mazziotta, Luca Biavati, Joseph Cataquiz Rimando, Sergio Rutella, Nicholas Borcherding, Sonali Parbhoo, Rupkatha Mukhopadhyay, Hanna A. Knaus, Peter Valent, Hubert Hackl, Ivan Borrello, Bruce R Blazar, Katerina Hatzi, Ivana Gojo, Leo Luznik

Blood blood.2023021680.

https://doi.org/10.1182/blood.2023021680

Published: 2024

Includes: Supplemental data

Journal Articles

Transcriptomic Features of Immune Exhaustion and Senescence Predict Outcomes and Define Checkpoint Blockade-Unresponsive Microenvironments in Acute Myeloid Leukemia

Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung On Yau, Rupkatha Mukhopadhyay, Heidi Altmann, Michael Kramer, Hanna A. Knaus, Joshua F. Zeidner, Vedran Radojcic, Andrea Arruda, Mark D. Minden, Sarah K Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik

Blood (2021) 138 (Supplement 1): 223.

https://doi.org/10.1182/blood-2021-145854

Published: 2021

Journal Articles

Bone Marrow GZMK + IL7R + Progenitor-Exhausted CD8 + T Cells Correlate with Sustained Clinical Remission in Patients with Acute Myeloid Leukemia (AML) Undergoing Chemotherapy

Francesco Mazziotta, Luca Biavati, Rupkatha Mukhopadhyay, Hanna A. Knaus, Ivan M. Borrello, Ivana Gojo, Leo Luznik

Blood (2021) 138 (Supplement 1): 521.

https://doi.org/10.1182/blood-2021-149150

Published: 2021