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Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation Following CAR T Therapy in Relapsed/Refractory Acute Lymphoblastic Leukemia

Natalie Rafaeli, David Marin, Celina Ledesma, Nitin Jain, Priti Tewari, Issa F. Khouri, Amanda L. Olson, Gheath Alatrash, Nicholas J. Short, Elias Jabbour, Katy Rezvani, Amin M. Alousi, Uday Popat, Richard E. Champlin, Elizabeth J. Shpall, Partow Kebriaei
Journal: Blood
Blood (2024) 144 (Supplement 1): 2810.
https://doi.org/10.1182/blood-2024-193954
Published: 2024
Journal Articles

Cord-Derived Invariant Natural Killer T Cells As Novel Cell Therapy to Improve the Outcome of Hematopoietic Stem Cell Transplantation

Abel Trujillo-Ocampo, Maison Grefe, Pamella Borges, Jelita Clinton, Hong He, Dan Li, Ling Yu, Martiela Vaz de Freitas, Lisa St. John, Karen Clise-Dwyer, Gheath Alatrash, Dinler Amaral Antues, Qing Ma, Jeffrey J. Molldrem, Elizabeth J. Shpall, Jin S. Im
Journal: Blood
Blood (2024) 144 (Supplement 1): 4818.
https://doi.org/10.1182/blood-2024-210168
Published: 2024
Journal Articles

Myeloablative Fractionated Busulfan, Fludarabine, Cladribine, Thiotepa and Venetoclax (Cladillac) Conditioning Regimen for Very High-Risk AML/MDS: A Phase 2 Trial

Uday Popat, Roland L. Bassett, Amin M. Alousi, Gheath Alatrash, Yosra M. Aljawai, Qaiser Bashir, George Chen, Warren B. Fingrut, Chitra Hosing, Jin S. Im, Partow Kebriaei, David Marin, Yago Nieto, Amanda L. Olson, Betul Oran, Muzaffar H. Qazilbash, Jeremy Ramdial, Neeraj Y. Saini, Portia Smallbone, Samer A. Srour, Benigno C. Valdez, Richard E. Champlin, Borje S. Andersson, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 506.
https://doi.org/10.1182/blood-2024-203338
Published: 2024
Journal Articles

CBX250 Is a Novel Cathepsin G Peptide-HLA-Targeting T Cell Engager That Exhibits High Tumor Antigen Selectivity and Potent Antileukemic Activity In Vivo

Benjamin H. Lee, Geraldine Paulus, Jennifer Helble, Preethi Sankaran, Tanzila Rahman, Delainey O'Connor, Melissa Bikowitz, Sarah Jaffe, Alona Kulesha, Bhupal Ban, Nga Sze Amanda Mak, Michael Princiotta, Chunhua Shi, Jun Yan, Hong He, Ningping Feng, Jeffrey J. Molldrem, Timothy Heffernan, Gheath Alatrash, Dmitri Wiederschain
Journal: Blood
Blood (2024) 144 (Supplement 1): 208.
https://doi.org/10.1182/blood-2024-201699
Published: 2024
Journal Articles

Efficacy and Safety of Pembrolizumab Added to Azacitidine Plus Venetoclax for Patients with Acute Myeloid Leukemia: Results from an Investigator-Initiated, Multi-Center, CTEP-Sponsored Randomized, Phase II Trial (BLAST AML-2)

Jessica M. Stempel, Geoffrey L. Uy, Shira N. Dinner, Ivana Gojo, Daniel Reed, Rupali Roy, Kenneth P Byrd, Swaroopa Yerrabothala, Catherine E. Lai, Kimberley Doucette, Anne Caldwell, Ondrej Blaha, Nikolai A. Podoltsev, Lourdes M Mendez, Jan Philipp Bewersdorf, Tariq Kewan, Ignacio Wistuba, Gheath Alatrash, Cara L Haymaker, Howard Streicher, Elad Sharon, Richard Little, Steven D. Gore, Jerald P. Radich, Brent L. Wood, Amer M. Zeidan, Rory M. Shallis
Journal: Blood
Blood (2024) 144 (Supplement 1): 736.
https://doi.org/10.1182/blood-2024-210370
Published: 2024
Journal Articles

AML Immunotherapy Using a Novel Tcrm-Based Bispecific Antibody That Targets a Leader Sequence Peptide Derived from Cathepsin G

Chunhua Shi, Ze Tian, Jun Yan, Mao Zhang, Pariya Sukhumalchandra, Edward Chang, Guojun Yang, Junping You, Meng Cui, Qing Shi, Anne Philips, Na Qiao, Anna Sergeeva, Lisa St. John, Hong He, Dongxing Zha, Jeffrey J. Molldrem, Gheath Alatrash
Journal: Blood
Blood (2023) 142 (Supplement 1): 1415.
https://doi.org/10.1182/blood-2023-189514
Published: 2023
Journal Articles

Incidence and Risk Factors of Veno-Occlusive Disease Are Different in Younger Versus Older Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Curtis Marcoux, Rima M. Saliba, Whitney Wallis, Sajad Khazal, Dristhi Ragoonanan, Gabriela Rondon, Priti Tewari, Uday R. Popat, Betul Oran, Amanda L. Olson, Qaiser Bashir, Muzaffar H. Qazilbash, Amin Alousi, Chitra Hosing, Yago Nieto, Gheath Alatrash, David Marin, Katayoun Rezvani, Issa F. Khouri, Samer A. Srour, Richard E. Champlin, Elizabeth J. Shpall, Partow Kebriaei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4920.
https://doi.org/10.1182/blood-2023-185025
Published: 2023
Journal Articles

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Irene Ganan-Gomez, Bijender Kumar, Juan Jose Rodriguez Sevilla, Feiyang Ma, Yi June Kim, Kelly S. Chien, Kate Nelson, Hui Yang, Roselyn Tan, Zongrui Li, Tomoyuki Tanaka, Hidetaka Uryu, Rashmi Kanagal-Shamanna, Sanam Loghavi, Gheath Alatrash, Rafael Bejar, Katayoun Rezvani, Koichi Takahashi, Guillermo Garcia-Manero, May Daher, MD, Simona Colla
Journal: Blood
Blood (2023) 142 (Supplement 1): 514.
https://doi.org/10.1182/blood-2023-184349
Published: 2023
Journal Articles

Patient Characteristics and Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Muzaffar H. Qazilbash, Hina N. Khan, Denái R. Milton, Oren Pasvolsky, Mark R. Tanner, Uday R. Popat, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Katayoun Rezvani, Yago Nieto, Betul Oran, Samer A. Srour, Neeraj Y. Saini, Amanda L. Olson, Sairah Ahmed, Gheath Alatrash, Gabriela Rondon, Marina Y. Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Qaiser Bashir, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4988.
https://doi.org/10.1182/blood-2023-181031
Published: 2023
Journal Articles

A Public Neoantigen Produced By the SF3B1 K700E Mutation Is a Bona Fide T Cell Target in AML/MDS

Noah J Tubo, Duncheng Wang, Qiuming He, Yibin Chen, Ho Ngai, Yanqing Huang, Celine Kerros, Xizeng Mao, Shoudan Liang, Hong He, Gheath Alatrash, Priya Koppikar, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 6816.
https://doi.org/10.1182/blood-2023-190199
Published: 2023
Journal Articles

CD47 Blockade Enhances Phagocytic Activity of the TCR-Mimic Antibody Hu8F4 Against HLA-A2+ AML

Anna Sergeeva, Hong He, Lisa St. John, Ling Yu, Rong Cai, Kathryn Ruissard, Karen Clise-Dwyer, Rolando Vedia, Dan Li, Qing Ma, Celine Kerros, Mithil Chokshi, Vanshika Jhonsa, Gang Bao, Gheath Alatrash, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 4176.
https://doi.org/10.1182/blood-2023-190099
Published: 2023
Journal Articles

Phase 1/2 Trial to Jointly Optimize Dose and Administration Schedule of Evomela in Newly Diagnosed Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation

Qaiser Bashir, Peter Thall, Dawen Sui, Jitesh Kawedia, Cristina Knape, Ruby Delgado, Jandi L Schindler, Uday R. Popat, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Yago Nieto, Betul Oran, Samer A. Srour, Neeraj Y. Saini, Amanda L. Olson, Sairah Ahmed, Gheath Alatrash, Gabriela Rondon, Hans C. Lee, Sheeba K. Thomas, Elisabet E. Manasanch, Krina K. Patel, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash
Journal: Blood
Blood (2023) 142 (Supplement 1): 4972.
https://doi.org/10.1182/blood-2023-189844
Published: 2023
Journal Articles

Phase I Study of the T-Cell Receptor-like Antibody, Hu8F4 in Patients with Relapsed and Refractory Myeloid Malignancies

Tapan M. Kadia, Hagop Kantarjian, Gheath Alatrash, Anna Sergeeva, Hong He, Lisa St. John, Priya Koppikar, Celine Kerros, Karen Clise-Dwyer, Kathryn Ruissard, Abhishek Maiti, Courtney D. DiNardo, Elias Jabbour, Srdan Verstovsek, Naveen Pemmaraju, Nitin Jain, Ghayas C. Issa, Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Aditi Shastri, Daniel R. Couriel, Maria Rhona Pinsoy, Sapna Parshottham, Richard E. Champlin, Jorge Cortes, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 1545.
https://doi.org/10.1182/blood-2023-189966
Published: 2023
Journal Articles

High-Throughput Identification of Graft-Vs-Leukemia TCRs in AML Patient Samples after Allogeneic Stem Cell Transplantation

Noah J Tubo, Duncheng Wang, Qiuming He, Yibin Chen, Ho Ngai, Yanqing Huang, Celine Kerros, Xizeng Mao, Shoudan Liang, Sachet Shukla, Arnau Peris Cuesta, Pavan Bachireddy, Julio Alcantara Montiel, Gheath Alatrash, Priya Koppikar, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 7168.
https://doi.org/10.1182/blood-2023-190330
Published: 2023
Journal Articles

Tagraxofusp Maintenance Post-Hematopoietic Stem Cell Transplantation Provides Long-Term Survival and Manageable Safety for a Patient with Blastic Plasmacytoid Dendritic Cell Neoplasm

Qaiser Bashir, Marina Y. Konopleva, Glorette Abueg, Jeremy Ramdial, Chitra Hosing, Samer A. Srour, Amin Alousi, Uday R. Popat, Yago Nieto, Gheath Alatrash, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 7058.
https://doi.org/10.1182/blood-2023-178874
Published: 2023
Journal Articles

Clinical Outcomes and Impact of Therapeutic Intervention in Patients (pts) with Acute Myeloid Leukemia (AML) with Recurrence of Measurable Residual Disease (MRD) after Achievement of MRD-Negative Remission

Walid Macaron, Farhad Ravandi, Tapan M. Kadia, Courtney D. DiNardo, Ghayas C. Issa, Naval Daver, Sa A Wang, Jeffrey L. Jorgensen, Keyur Patel, Sanam Loghavi, Marina Konopleva, Musa Yilmaz, Elias Jabbour, Abhishek Maiti, Hussein A Abbas, Elizabeth J Shpall, Uday R Popat, Gheath Alatrash, Sherry A. Pierce, Hagop Kantarjian, Nicholas Short
Journal: Blood
Blood (2022) 140 (Supplement 1): 543–545.
https://doi.org/10.1182/blood-2022-156955
Published: 2022
Journal Articles

Son Vs Daughter Haploidentical Donor for T Cell-Replete HCT with Ptcy Prophylaxis

Rohtesh S. Mehta, Rima M. Saliba, Amin M Alousi, Gheath Alatrash, Qaiser Bashir, Chitra Hosing, Partow Kebriaei, Issa F. Khouri, Yago Nieto, Betul Oran, Uday R Popat, Muzaffar H Qazilbash, Jeremy L. Ramdial, Gabriela Rondon, Samer A Srour, Katy Rezvani, Richard E Champlin, Elizabeth J Shpall, Kai Cao
Journal: Blood
Blood (2022) 140 (Supplement 1): 7649–7650.
https://doi.org/10.1182/blood-2022-166381
Published: 2022
Journal Articles

Targetable Cellular Etiology of Prolonged Cytopenia Following CD19 CAR T-Cell Therapy

Xubin Li, Qing Deng, Jared Henderson, Grace Watson, Laurel Deaton, Taylor Cain, Luis Fayad, Swaminathan Padmanabhan Iyer, Fredrick B. Hagemeister, Loretta J. Nastoupil, Nathan H. Fowler, Jason Westin, Raphael Steiner, Ranjit Nair, Sairah Ahmed, Gheath Alatrash, Sattva S. Neelapu, Paolo Strati, Michael R Green
Journal: Blood
Blood (2022) 140 (Supplement 1): 4502–4503.
https://doi.org/10.1182/blood-2022-166308
Published: 2022