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Journal Articles

Updated Results from a Phase II Study of Vibecotamab, a CD3-CD123 Bispecific T-Cell Engaging Antibody, for MDS or CMML after Hypomethylating Failure and in MRD-Positive AML

Daniel Nguyen, Farhad Ravandi, Sa A. Wang, Jeffrey L. Jorgensen, Wei WANG, Sanam Loghavi, Jaehyun Lee, Pavan Bachireddy, Courtney D. DiNardo, Kelly S. Chien, Guillermo Montalban-Bravo, Ghayas C. Issa, Abhishek Maiti, Yesid Alvarado Valero, Naval Daver, Elias Jabbour, Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Danielle T Nguyen, Uday Popat, Elizabeth J. Shpall, Guillermo Garcia-Manero, Hagop Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 1007.
https://doi.org/10.1182/blood-2024-208684
Published: 2024
Journal Articles

Impact of Flow Cytometry-Based Measurable Residual Disease Clearance Kinetics in Patients with Acute Myeloid Leukemia Undergoing Intensive Chemotherapy

Wei-Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Sherry Pierce, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 1572.
https://doi.org/10.1182/blood-2024-212036
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia: 3-Year Update

Fadi G. Haddad, Hagop M. Kantarjian, Nicholas J. Short, Jayastu Senapati, Nitin Jain, Koji Sasaki, Jeffrey L. Jorgensen, Joseph E. Jabbour, Sa A. Wang, Yesid Alvarado Valero, Xuemei Wang, Alessandra Ferrajoli, Diane Habib, Jan A. Burger, Courtney D. DiNardo, Zena Komrokji, Lucia Masarova, Tapan M. Kadia, Guillermo Garcia-Manero, Farhad Ravandi, Rebecca Garris, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4194.
https://doi.org/10.1182/blood-2024-210642
Published: 2024
Journal Articles

Peripheral Blood CAR T-Cell Level Using a Clia-Validated Assay Is Prognostic for Treatment Response and Icans in Large B-Cell Lymphoma

Anath Lionel, Naishu Kui, Ryan Sun, Eslam Aboismail, Sanjit Om Tewari, Ajlan Al Zaki, Sushanth Gouni, Preetesh Jain, Dai Chihara, Swaminathan P Iyer, Michael Wang, Ranjit Nair, Luis Enrique Malpica Castillo, Hun Ju Lee, Chijioke Nze, Luis E. Fayad, Frederick Hagemeister, Maria Alma Rodriguez, Amy A. Ayers, Cristina Gutierrez, Gabriela Rondon, Fareed Khawaja, Partow Kebriaei, Elizabeth J. Shpall, Christopher R. Flowers, Jason R. Westin, Paolo Strati, Wei WANG, Sa A. Wang, Sairah Ahmed, Sattva S. Neelapu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3001.
https://doi.org/10.1182/blood-2024-208300
Published: 2024
Journal Articles

Myeloid Progenitor Cells with Preleukemic Immunophenotypes Are Common in Myelodysplasia-Related and NPM1- mutated Acute Myeloid Leukemia and Should Not be Interpreted As Measurable Residual Disease

Sanam Loghavi, Sa A. Wang, Wei-Ying Jen, Wei Wang, Hong Fang, Shaoying Li, Sofia A. Garces, Andres E Quesada, Jie Xu, Chi Young Ok, Shimin Hu, Jeffrey L. Jorgensen, Guilin Tang, Cedric Nasnas, Omer Karrar, Ghayas C. Issa, Naval Daver, Courtney D. DiNardo, Tapan M. Kadia, Hagop M. Kantarjian, L. Jeffrey Medeiros, Farhad Ravandi, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 4336.
https://doi.org/10.1182/blood-2024-209462
Published: 2024
Journal Articles

Phase 2 study of inotuzumab ozogamicin for measurable residual disease in acute lymphoblastic leukemia in remission

Clinical Trials & Observations Brief Report
Elias Jabbour, Fadi G. Haddad, Nicholas J. Short, Jayastu Senapati, Nitin Jain, Koji Sasaki, Jeffrey Jorgensen, Sa A. Wang, Yesid Alvarado, Xuemei Wang, Courtney DiNardo, Lucia Masarova, Tapan Kadia, Rebecca S. Garris, Farhad Ravandi, Hagop Kantarjian
Journal: Blood
Blood (2024) 143 (5): 417–421.
https://doi.org/10.1182/blood.2023022330
Published: 2024
Includes: Supplemental data
Journal Articles

Multicenter Retrospective Analysis of Eosinophilic Myeloid Neoplasms

Eoghan Molloy, William Shomali, Maggie J Cox, Joseph Butterfield, Julien Catherine, Michael W. Deininger, Juehua Gao, Grzegorz Helbig, Gabriela S. Hobbs, Fuli Jia, Jean Emmanuel Kahn, Paneez Khoury, Hirsh Komarow, Andrew T. Kuykendall, Orly Leiva, Guillaume Lefèvre, Hana I Lim, Bridget Marcellino, Irina Maric, John Mascarenhas, Elena Mishchenko, Stephen T. Oh, Eric Padron, Sandhya R Panch, Ami Patel, Cecelia Perkins, Thanai Pongdee, Florence Roufosse, Andrew I. Schafer, Brady L. Stein, Srdan Verstovsek, Sa A. Wang, Ling Zhang, Jason Gotlib, Amy D Klion
Journal: Blood
Blood (2023) 142 (Supplement 1): 4576.
https://doi.org/10.1182/blood-2023-187092
Published: 2023
Journal Articles

Ibrutinib, Fludarabine, Cyclophosphamide and Obinutuzumab (iFCG) for Firstline Treatment of Patients with CLL with Mutated IGHV and without Del(17p)/ TP53 Mutation: Six-Year Follow-up Analyses

Nitin Jain, Philip Thompson, Akhil Jain, Jan A. Burger, Alessandra Ferrajoli, Jayastu Senapati, Koichi Takahashi, Mahesh Swaminathan, Zeev Estrov, Gautam Borthakur, Prithviraj Bose, Tapan M. Kadia, Naveen Pemmaraju, Koji Sasaki, Divyam Bansal, Marina Y. Konopleva, Elias Jabbour, Naveen Garg, Xuemei Wang, Rashmi Kanagal-Shamanna, Keyur P. Patel, Wei Wang, Sa A. Wang, Jeffrey L. Jorgensen, Wanda Lopez, Ana Ayala, William Plunkett, Varsha Gandhi, Hagop M. Kantarjian, Susan M. O'Brien, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3267.
https://doi.org/10.1182/blood-2023-188084
Published: 2023
Journal Articles

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Himachandana Atluri, Jeremy DiGennaro, Keyur P. Patel, Mark Routbort, Betul Oran, Ghayas C. Issa, Nicholas J. Short, Naval Daver, Tapan M. Kadia, Farhad Ravandi, Uday R. Popat, Richard E. Champlin, Elizabeth J. Shpall, Sherry Pierce, Rashmi Kanagal-Shamanna, Chi Young Ok, Guilin Tang, Sa A. Wang, Raja Luthra, Audrey Lasry, Bettina Nadorp, Antonia Chroni, Ann-Kathrin Eisfeld, Iannis Aifantis, Najla H Al Ali, David A Sallman, Jeffrey Lancet, Onyee Chan, Eric Padron, Zhuoer Xie, L. Jeffrey Medeiros, Courtney D. DiNardo, Rami S. Komrokji, Sanam Loghavi
Journal: Blood
Blood (2023) 142 (Supplement 1): 959.
https://doi.org/10.1182/blood-2023-188319
Published: 2023
Journal Articles

Combined Ibrutinib and Venetoclax for First-Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL): 5-Year Follow-up Data

Nitin Jain, Michael J. Keating, Philip A. Thompson, Alessandra Ferrajoli, Jayastu Senapati, Jan A. Burger, Gautam Borthakur, Mahesh Swaminathan, Koichi Takahashi, Zeev Estrov, Marina Y. Konopleva, Koji Sasaki, Tapan M. Kadia, Naveen Pemmaraju, Naval Daver, Elias Jabbour, Courtney D. DiNardo, Yesid Alvarado Valero, Musa Yilmaz, Prithviraj Bose, Maro Ohanian, Rashmi Kanagal-Shamanna, Keyur Patel, Jeffrey L. Jorgensen, Sa A. Wang, Sameh Nassar, Naveen Garg, Hyunsoo Hwang, Xuemei Wang, Nichole Cruz, Ana Ayala, William Plunkett, Hagop M. Kantarjian, Varsha Gandhi, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 4635.
https://doi.org/10.1182/blood-2023-189711
Published: 2023
Journal Articles

Single-Cell Proteogenomics Analysis of AML Samples Treated with Decitabine and Venetoclax Reveals Divergent Treatment Escape Mechanisms

Yi June Kim, Zongrui Li, Abhishek Maiti, Tomoyuki Tanaka, Hidetaka Uryu, Ken Furudate, Kala Hayes, Naval Daver, Naveen Pemmaraju, Tapan M. Kadia, Farhad Ravandi, Nicholas J. Short, Maro Ohanian, Gautam Borthakur, Nitin Jain, Ghayas C. Issa, Lucia Masarova, Steven M. Kornblau, William G. Wierda, Sanam Loghavi, Sa A. Wang, Guillermo Garcia-Manero, Hagop Kantarjian, Courtney D. DiNardo, Marina Y. Konopleva, Koichi Takahashi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2931.
https://doi.org/10.1182/blood-2023-190400
Published: 2023
Journal Articles

Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)

Luca Lanino, Somedeb Ball, Jan Philipp Bewersdorf, Monia Marchetti, Giulia Maggioni, Erica Travaglino, Najla H Al Ali, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Maria Diez-Campelo, Avani M Singh, Akriti Gupta Jain, Luis E. Aguirre, Sara M. Tinsley-Vance, Zaker I. Schwabkey, Onyee Chan, Zhuoer Xie, Andrew M. Brunner, Andrew T. Kuykendall, John M. Bennett, Rena Buckstein, Rafael Bejar, Hetty E. Carraway, Amy E. DeZern, Elizabeth A. Griffiths, Stephanie Halene, Robert Hasserjian, Jeffrey Lancet, Alan F. List, Sanam Loghavi, Olatoyosi Odenike, Eric Padron, Mrinal M. Patnaik, Gail J. Roboz, Maximilian Stahl, Mikkael A. Sekeres, David Peter Steensma, Michael R. Savona, Justin Taylor, Mina Xu, Kendra Sweet, David A Sallman, Stephen D. Nimer, Christopher S. Hourigan, Andrew H. Wei, Elisabetta Sauta, Saverio D'Amico, Gianluca Asti, Gastone Castellani, Uma M. Borate, Guillermo Sanz, Fabio Efficace, Steven D. Gore, Tae Kon Kim, Naval Daver, Guillermo Garcia-Manero, María Rozman, Alberto Orfao, Sa A. Wang, M. Kathy Foucar, Ulrich Germing, Torsten Haferlach, Phillip Scheinberg, Yasushi Miyazaki, Marcelo Iastrebner, Austin Kulasekararaj, Thomas Cluzeau, Shahram Kordasti, Arjan A. van de Loosdrecht, Lionel Ades, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta
Journal: Blood
Blood (2023) 142 (Supplement 1): 998.
https://doi.org/10.1182/blood-2023-186580
Published: 2023
Journal Articles

A Phase II Study of Vibecotamab, a CD3-CD123 Bispecific T-Cell Engaging Antibody, for MDS or CMML after Hypomethylating Failure and in MRD-Positive AML

Daniel Nguyen, Farhad Ravandi, Sa A. Wang, Jeffrey L. Jorgensen, Wei Wang, Kelly S. Chien, Guillermo Montalban-Bravo, Ghayas C. Issa, Abhishek Maiti, Yesid Alvarado Valero, Naval Daver, Courtney D. DiNardo, Elias Jabbour, Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Jaehyun Lee, Pavan Bachireddy, Uday R. Popat, Guillermo Garcia-Manero, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2023) 142 (Supplement 1): 322.
https://doi.org/10.1182/blood-2023-190693
Published: 2023
Journal Articles

Does Detection of <20% Lymphoblasts in Patients with CML Herald Imminent Blast Crisis? a Study from BCR::ABL1 Pathology Group

Zimu Gong, Lianqun Qiu, Joseph DiGiuseppe, Mengxing Xue, Lorinda Soma, Wei Wang, Yi Zhou, Qi Shen, Mingqing Zhu, Anisha Naik, Weina Chen, Wei J Wang, Sa A. Wang, L. Jeffrey Medeiros, Elias Jabbour, Hagop M. Kantarjian, Jorge Cortes, Jerald P. Radich, Joseph D. Khoury, Andreas Hochhaus, Jane F Apperley, Suning Chen, Kikkeri N Naresh, Shimin Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2023-187020
Published: 2023
Journal Articles

The Adverse Effect of Myelodysplasia-Related Mutations in De Novo Acute Myeloid Leukemia Is Associated with Higher Variant Allelic Frequency (VAF): A Proposal for a Numeric Cutoff for Variant Allelic Frequency

Sanam Loghavi, Patrick K Reville, Curtis A Lachowiez, Mark Routbort, Keyur Patel, Rashmi Kanagal-Shamanna, Chi Young Ok, Joseph D. Khoury, Guilin Tang, Sa A Wang, Tapan M. Kadia, Naval Daver, Koichi Takahashi, Guillermo Garcia-Manero, Sherry A. Pierce, Marina Konopleva, L. Jeffrey Medeiros, Hagop Kantarjian, Farhad Ravandi, Nicholas Short, Courtney D. DiNardo
Journal: Blood
Blood (2022) 140 (Supplement 1): 6306–6308.
https://doi.org/10.1182/blood-2022-164494
Published: 2022
Journal Articles

Improved Outcomes with Low-Dose Inotuzumab and Mini-Hyper-CVD Followed By Blinatumomab Consolidation in Relapsed-Refractory Acute Lymphoblastic Leukemia: Results of a Phase II Study

Fadi Haddad, Elias Jabbour, Nicholas Short, Nitin Jain, Emmanuel Almanza Huante, Koji Sasaki, Patrice Nasnas, Farhad Ravandi, Partow Kebriaei, Xuelin Huang, Marina Konopleva, Guillermo Garcia-Manero, Richard E Champlin, Tapan M. Kadia, Koichi Takahashi, Naval Daver, Joseph D. Khoury, Jeffrey L. Jorgensen, Sa A Wang, Jovitta Jacob, Rebecca Garris, Hagop Kantarjian
Journal: Blood
Blood (2022) 140 (Supplement 1): 11698–11701.
https://doi.org/10.1182/blood-2022-170049
Published: 2022
Journal Articles

Utility of Flow Cytometry in Monitoring of Measurable Residual Disease in Patients with Hairy Cell Leukemia

Tareq Abuasab, Fadi Haddad, Shehab Fareed Mohamed, Jeffrey L. Jorgensen, Sa A Wang, Philip A. Thompson, Tapan M. Kadia, Yesid Alvarado, Sherry A. Pierce, Michael J. Keating, David McCue, Hagop Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9385–9386.
https://doi.org/10.1182/blood-2022-165639
Published: 2022
Journal Articles

Clinical Outcomes and Impact of Therapeutic Intervention in Patients (pts) with Acute Myeloid Leukemia (AML) with Recurrence of Measurable Residual Disease (MRD) after Achievement of MRD-Negative Remission

Walid Macaron, Farhad Ravandi, Tapan M. Kadia, Courtney D. DiNardo, Ghayas C. Issa, Naval Daver, Sa A Wang, Jeffrey L. Jorgensen, Keyur Patel, Sanam Loghavi, Marina Konopleva, Musa Yilmaz, Elias Jabbour, Abhishek Maiti, Hussein A Abbas, Elizabeth J Shpall, Uday R Popat, Gheath Alatrash, Sherry A. Pierce, Hagop Kantarjian, Nicholas Short
Journal: Blood
Blood (2022) 140 (Supplement 1): 543–545.
https://doi.org/10.1182/blood-2022-156955
Published: 2022
Journal Articles

Achievement of Measurable Residual Disease (MRD) Negativity Supersedes Treatment Intensity in Predicting the Outcome of Patients with Acute Myeloid Leukemia

Alexandre Bazinet, Tapan M. Kadia, Nicholas Short, Gautam Borthakur, Sa A Wang, Sanam Loghavi, Jeffrey L. Jorgensen, Keyur P. Patel, Courtney D. DiNardo, Naval Daver, Yesid Alvarado, Fadi Haddad, Sherry A. Pierce, Graciela M. Nogueras González, Abhishek Maiti, Michael Andreeff, Elias Jabbour, Marina Konopleva, Xuelin Huang, Hagop Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2022) 140 (Supplement 1): 2267–2269.
https://doi.org/10.1182/blood-2022-162892
Published: 2022