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Journal Articles

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

Blood (2024) 144 (Supplement 1): 5634.

https://doi.org/10.1182/blood-2024-209240

Published: 2024

Journal Articles

MISTRG6kit W41 : Enhanced Engraftment in a Cytokine Humanized Patient-Derived Xenotransplantation Mouse Model

Amro Baassiri, Jamie Maziarz, Holly Nicole Blackburn, Hannah Maul-Newby, Jennifer VanOudenhove, Xuan Zhang, Martin Matthews, Sambuddha Paul, Wei Liu, Esen Sefik, Nathan Salomonis, H. Leighton Grimes, Richard Flavell, Stephanie Halene

Blood (2024) 144 (Supplement 1): 1815.

https://doi.org/10.1182/blood-2024-211908

Published: 2024

Journal Articles

O6-Guanine Targeting Novel DNA Cross-Linker and ATR Inhibitor Combination for MGMT-Silenced IDH1/2 Mutant Acute Myeloid Leukemia

Prateek Bhardwaj, Ranjini Sundaram, Sam Friedman, Amro Baassiri, Martin Matthews, Jennifer VanOudenhove, Susan Gueble, Stephanie Halene, Ranjit Bindra

Blood (2024) 144 (Supplement 1): 6130.

https://doi.org/10.1182/blood-2024-210621

Published: 2024

Journal Articles

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Xuan Zhang, Guangyuan Li, Anna Oliverio, Jennifer VanOudenhove, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, H. Leighton Grimes, Nathan Salomonis

Blood (2024) 144 (Supplement 1): 1810.

https://doi.org/10.1182/blood-2024-211099

Published: 2024

Journal Articles

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Ahmad Kiwan, Tariq Kewan, Carlos Bravo-Perez, Valeria Visconte, Carmelo Gurnari, Arda Durmaz, Alexa Siddon, Stephanie Halene, Tarsheen Sethi, Jaroslaw Maciejewski, Francine M. Foss

Blood (2024) 144 (Supplement 1): 4436.

https://doi.org/10.1182/blood-2024-209344

Published: 2024

Journal Articles

Unraveling the Drivers of the Stress Granule Signature in Splicing Factor-Mutant Myeloid Malignancies

Giulia Biancon, Emma Busarello, Matthew Cheng, Simone Sidoli, Jennifer VanOudenhove, Giorgia Bucciarelli, Toma Tebaldi, Stephanie Halene

Blood (2024) 144 (Supplement 1): 4117.

https://doi.org/10.1182/blood-2024-211265

Published: 2024

Journal Articles

Immune Landscape and Outcomes of Patients with RNA Splicing Factor-Mutant Acute Myeloid Leukemia and Myelodysplastic Syndromes Treated with Azacitidine +/- the Anti-PD-L1 Antibody Durvalumab

Jan Philipp Bewersdorf, Vanessa Hasle, Rory M. Shallis, Ethan G. Thompson, Daniel Lopes De Menezes, Shelonitda Rose, Isaac W. Boss, Lourdes Mendez, Nikolai A. Podoltsev, Maximilian Stahl, Tariq Kewan, Stephanie Halene, Torsten Haferlach, Brian Fox, Amer M. Zeidan

Blood (2024) 144 (Supplement 1): 4585.

https://doi.org/10.1182/blood-2024-194929

Published: 2024

Journal Articles

Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)

Luca Lanino, Somedeb Ball, Jan Philipp Bewersdorf, Monia Marchetti, Giulia Maggioni, Erica Travaglino, Najla H Al Ali, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Maria Diez-Campelo, Avani M Singh, Akriti Gupta Jain, Luis E. Aguirre, Sara M. Tinsley-Vance, Zaker I. Schwabkey, Onyee Chan, Zhuoer Xie, Andrew M. Brunner, Andrew T. Kuykendall, John M. Bennett, Rena Buckstein, Rafael Bejar, Hetty E. Carraway, Amy E. DeZern, Elizabeth A. Griffiths, Stephanie Halene, Robert Hasserjian, Jeffrey Lancet, Alan F. List, Sanam Loghavi, Olatoyosi Odenike, Eric Padron, Mrinal M. Patnaik, Gail J. Roboz, Maximilian Stahl, Mikkael A. Sekeres, David Peter Steensma, Michael R. Savona, Justin Taylor, Mina Xu, Kendra Sweet, David A Sallman, Stephen D. Nimer, Christopher S. Hourigan, Andrew H. Wei, Elisabetta Sauta, Saverio D'Amico, Gianluca Asti, Gastone Castellani, Uma M. Borate, Guillermo Sanz, Fabio Efficace, Steven D. Gore, Tae Kon Kim, Naval Daver, Guillermo Garcia-Manero, María Rozman, Alberto Orfao, Sa A. Wang, M. Kathy Foucar, Ulrich Germing, Torsten Haferlach, Phillip Scheinberg, Yasushi Miyazaki, Marcelo Iastrebner, Austin Kulasekararaj, Thomas Cluzeau, Shahram Kordasti, Arjan A. van de Loosdrecht, Lionel Ades, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta

Blood (2023) 142 (Supplement 1): 998.

https://doi.org/10.1182/blood-2023-186580

Published: 2023

Journal Articles

Mutant p53 Drives the Development of Myelodysplastic Syndromes Via Dysregulating Pre-mRNA Splicing in Hematopoietic Stem and Progenitor Cells

Sergio Barajas, Sisi Chen, Sasidhar Vemula, Yuxia Yang, Edward Simpson, Wenjie Cai, Shiyu Xiao, Hongxia Chen, Stephanie Halene, Madina Sukhanova, Yunlong Liu, Omar Abdel-Wahab, Yan Liu

Blood (2023) 142 (Supplement 1): 4582.

https://doi.org/10.1182/blood-2023-180382

Published: 2023

Journal Articles

Evaluation of Metabolic Profile in Monoclonal Gammopathy of Undetermined Significance and Asymptomatic Multiple Myeloma

Sabrina L. Browning, Allison J. Li, Terri L. Parker, Noffar Bar, Tara Anderson, Erica Stevens, Yuxin Liu, Martin Matthews, Jennifer VanOudenhove, Rebecca Cardone, Qiushi Sun, Robert Hale, Stephanie Halene, Richard Kibbey, Natalia Neparidze

Blood (2023) 142 (Supplement 1): 4774.

https://doi.org/10.1182/blood-2023-186401

Published: 2023

Journal Articles

CAR T-Related Toxicities Based on Dynamic Proteomic Profiles Identifies Risk Factors for Cytokine Release Syndrome (CRS) and Immune Effector Cell -Associated Neurotoxicity Syndrome (ICANS)

Tariq Kewan, Sayeef Mirza, Alexander B Pine, Yusuf Rasheed, Ramzi Hamouche, Etienne Leveille, George Goshua, Sean X Gu, Yuxin Liu, Jennifer Vanoudenhove, Noffar Bar, Natalia Neparidze, Francine M. Foss, Lohith Gowda, Iris Isufi, Stephanie Halene, Alfred I Lee, Stuart Seropian

Blood (2023) 142 (Supplement 1): 2132.

https://doi.org/10.1182/blood-2023-187295

Published: 2023

Journal Articles

Feasibility, Safety and Predictors of Outcomes of Patients with Newly Diagnosed Acute Myeloid Leukemia Discharged “Early” after Intensive Induction Therapy

Cameron Hunter, Wei Cheng, Stephanie Halene, Lourdes Mendez, Nikolai A. Podoltsev, Amer M. Zeidan, Lisa Barbarotta, Rory M. Shallis

Blood (2023) 142 (Supplement 1): 589.

https://doi.org/10.1182/blood-2023-182989

Published: 2023

Journal Articles

Characterizing Outpatient Classical Hematology Referrals at an Academic Healthcare System

Eric Y Chang, Anna Kress, Friedrich Ackermann, Monica Fradkin, Stephanie Halene, Elizabeth Herbert, Lisa Shomsky, Latha Sudhakar, Alfred I Lee, Robert D Bona

Blood (2023) 142 (Supplement 1): 7196.

https://doi.org/10.1182/blood-2023-186065

Published: 2023

Journal Articles

Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution

Olisaemeka Ogbue, Tariq Kewan, Omar Mehkri, Francois Fadell, Ishani Nautiyal, Megan Reynold, Arda Durmaz, Jennifer VanOudenhove, Hussein Awada, Serhan Unlu, Abhay Singh, Valeria Visconte, Lourdes Mendez, David S. Bosler, Abhijit Duggal, Stephanie Halene, Jaroslaw P. Maciejewski, Mohammed J Al-Jaghbeer, Carmelo Gurnari

Blood (2023) 142 (Supplement 1): 2691.

https://doi.org/10.1182/blood-2023-187424

Published: 2023

Journal Articles

Spatial Multiomics Profiling of Angioimmunoblastic T-Cell Lymphoma

Mina Xu, Stephanie Halene, Rong Fan, Archibald Enninful

Blood (2023) 142 (Supplement 1): 6109.

https://doi.org/10.1182/blood-2023-190647

Published: 2023

Journal Articles

Trial in Progress: Venetoclax in Combination with ASTX727, an All-Oral Therapy for Chronic Myelomonocytic Leukemia and Other MDS/MPN with Excess Blasts (VICTORY MDS/MPN): A Randomized, Phase 2 Trial

Rory M. Shallis, Ondrej Blaha, Stephanie Halene, Lourdes Mendez, Nikolai A. Podoltsev, Anne Caldwell, Jan Philipp Bewersdorf, Richard F. Little, Richard Piekarz, Mrinal M. Patnaik, Steven D. Gore, Amer M. Zeidan

Blood (2023) 142 (Supplement 1): 3252.

https://doi.org/10.1182/blood-2023-182814

Published: 2023

Journal Articles

Harmonizing the Annotation of Hematopoietic Populations in Single-Cell Atlases with the Cell Marker Accordion

Emma Busarello, Zuhairia Ibnat, Giulia Biancon, Jennifer VanOudenhove, Fabio Lauria, Gabriella Viero, Stephanie Halene, Toma Tebaldi

Blood (2022) 140 (Supplement 1): 4968–4969.

https://doi.org/10.1182/blood-2022-162180

Published: 2022

Journal Articles

Chronic Inflammation Drives p53 Mutant Clonal Hematopoiesis Via Activating the NLRP1 Inflammasome

Sergio of Barajas, Sasidhar Vemula, Sisi Chen, Hongxia Chen, Wenjie Cai, Shiyu Xiao, Stephanie Halene, Omar Abdel-Wahab, Linsey Mayo, Sharon A. Savage, Yan Liu

Blood (2022) 140 (Supplement 1): 5743–5744.

https://doi.org/10.1182/blood-2022-169754

Published: 2022

Journal Articles

Impact of Allelic State on Overall Survival in TP53- mutant Acute Myeloid Leukemia (AML) and Higher Risk Myelodysplastic Syndromes (HR-MDS)

Jan Philipp Bewersdorf, Vanessa Hasle, Rory Michael Shallis, Ethan G. Thompson, Daniel Lopes de Menezes, Shelonitda Rose, Isaac W. Boss, Stephanie Halene, Torsten Haferlach, Brian Fox, Amer M. Zeidan

Blood (2022) 140 (Supplement 1): 8910–8911.

https://doi.org/10.1182/blood-2022-158592

Published: 2022

Journal Articles

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

Xuan Zhang, Baobao (Annie) Song, Mohammad Daud Khan, Kyle Ferchen, Chih-Hsing Chou, Guangyuan Li, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, Nathan Salomonis, H. Leighton Grimes

Blood (2022) 140 (Supplement 1): 9759–9760.

https://doi.org/10.1182/blood-2022-169300

Published: 2022

NARROW

Impact of Sepsis and Stress Hematopoiesis on the Acquisition and Persistence of Clonal Hematopoiesis

MISTRG6kit W41 : Enhanced Engraftment in a Cytokine Humanized Patient-Derived Xenotransplantation Mouse Model

O6-Guanine Targeting Novel DNA Cross-Linker and ATR Inhibitor Combination for MGMT-Silenced IDH1/2 Mutant Acute Myeloid Leukemia

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Unraveling the Drivers of the Stress Granule Signature in Splicing Factor-Mutant Myeloid Malignancies

Immune Landscape and Outcomes of Patients with RNA Splicing Factor-Mutant Acute Myeloid Leukemia and Myelodysplastic Syndromes Treated with Azacitidine +/- the Anti-PD-L1 Antibody Durvalumab

Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)

Mutant p53 Drives the Development of Myelodysplastic Syndromes Via Dysregulating Pre-mRNA Splicing in Hematopoietic Stem and Progenitor Cells

Evaluation of Metabolic Profile in Monoclonal Gammopathy of Undetermined Significance and Asymptomatic Multiple Myeloma

CAR T-Related Toxicities Based on Dynamic Proteomic Profiles Identifies Risk Factors for Cytokine Release Syndrome (CRS) and Immune Effector Cell -Associated Neurotoxicity Syndrome (ICANS)

Feasibility, Safety and Predictors of Outcomes of Patients with Newly Diagnosed Acute Myeloid Leukemia Discharged “Early” after Intensive Induction Therapy

Characterizing Outpatient Classical Hematology Referrals at an Academic Healthcare System

Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution

Spatial Multiomics Profiling of Angioimmunoblastic T-Cell Lymphoma

Trial in Progress: Venetoclax in Combination with ASTX727, an All-Oral Therapy for Chronic Myelomonocytic Leukemia and Other MDS/MPN with Excess Blasts (VICTORY MDS/MPN): A Randomized, Phase 2 Trial

Harmonizing the Annotation of Hematopoietic Populations in Single-Cell Atlases with the Cell Marker Accordion

Chronic Inflammation Drives p53 Mutant Clonal Hematopoiesis Via Activating the NLRP1 Inflammasome

Impact of Allelic State on Overall Survival in TP53- mutant Acute Myeloid Leukemia (AML) and Higher Risk Myelodysplastic Syndromes (HR-MDS)

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

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American Society of Hematology

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American Society of Hematology

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