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Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Blood (2023) 141 (19): 2359–2371.

https://doi.org/10.1182/blood.2022018244

Published: 2023

Includes: Supplemental data

Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Blood (2021) 138 (Supplement 1): 3271.

https://doi.org/10.1182/blood-2021-145927

Published: 2021

Journal Articles

Vitamin C Enhances PARPi Efficacy for the Treatment of AML

John P Brabson, Tiffany Leesang, Byron Fang, Jingjing Wang, Victoria Strippoli, Yoon-Sing Yap, Sofia Mohammad, Carolina Bañuelos, Peter Lyon, Sana Chaudhry, Minh Lam, Benjamin G Neel, Stephen Nimer, Ramiro E Verdun, Daniel Bilbao, Maria E. Figueroa, Luisa Cimmino

Blood (2021) 138 (Supplement 1): 1168.

https://doi.org/10.1182/blood-2021-153884

Published: 2021

Journal Articles

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks

Gloria Mas Martin, PhD, Na Man, Daniel Karl, PhD, Concepcion Martinez, B.S., Stephanie Duffort, Hidehiro Itonaga, MD PhD, Adnan K Mookhtiar, BS, Daniel Bilbao, PhD, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, PhD, Francisco Vega, MDPhD, Scott C. Kogan, MD, Stephen Nimer, MD

Blood (2020) 136 (Supplement 1): 13.

https://doi.org/10.1182/blood-2020-142030

Published: 2020

Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD

Blood (2019) 134 (Supplement_1): 561.

https://doi.org/10.1182/blood-2019-130507

Published: 2019

Journal Articles

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Xiaoqing Lu, Tharu M. Fernando, Chen Lossos, Nevin Yusufova, Fan Liu, Lorena Fontán, Matthew Durant, Huimin Geng, Jacob Melnick, Yuan Luo, Francisco Vega, Vincent Moy, Giorgio Inghirami, Stephen Nimer, Ari M. Melnick, Izidore S. Lossos

Blood (2018) 132 (19): 2026–2039.

https://doi.org/10.1182/blood-2018-02-831438

Published: 2018

Includes: Supplemental data

Journal Articles

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

Fan LIU, PhD, Guoyan Cheng, PhD, Fabiana Perna, MD PhD, Xu Haiming, PhD, Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Stephen Nimer, MD

Blood (2014) 124 (21): 4335.

https://doi.org/10.1182/blood.V124.21.4335.4335

Published: 2014

Journal Articles

Mutation Profiling of Therapy-Related Myeloid Neoplasms Using Next-Generation Sequencing Demonstrates Distinct Profiles from De Novo Disease

Alan H. Shih, MDPhD, Franck Rapaport, PhD, Stephen S. Chung, MD, Emily K Dolezal, Sean Hobson, MA, Mary K Amato, Christopher Y. Park, MD PhD, Mikkael A. Sekeres, MD MS, Marcel R.M. van den Brink, MD PhD, Stephen Nimer, MD, Ross L. Levine, MD, Jaroslaw P. Maciejewski, MD PhD, Virginia M. Klimek, MD

Blood (2014) 124 (21): 4611.

https://doi.org/10.1182/blood.V124.21.4611.4611

Published: 2014

Journal Articles

DNA Hydroxymethylation Profiling Reveals That WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

Blood (2014) 124 (21): 365.

https://doi.org/10.1182/blood.V124.21.365.365

Published: 2014

Journal Articles

Role of p21 in a Mouse Model of NUP98-HOXD13 Fusion Driven Myelodysplastic Syndromes (MDS)

Haiming Xu, PhD, Tony R Deblassio, MS, Scott A. Armstrong, MD PhD, Stephen Nimer, MD

Blood (2014) 124 (21): 4616.

https://doi.org/10.1182/blood.V124.21.4616.4616

Published: 2014

Journal Articles

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Andriana Kotini, PhD, Jeffrey J Delrow, PhD, Timothy A. Graubert, MD, Stephen Nimer, MD, Eirini P Papapetrou, MD PhD

Blood (2014) 124 (21): 524.

https://doi.org/10.1182/blood.V124.21.524.524

Published: 2014

Journal Articles

Comprehensive Mutational Profiling In Myelodysplastic Syndromes Treated With Decitabine and Tretinoin

Alan H. Shih, MD PhD, Sean M. Devlin, PhD, Emily K. Dolezal, Kristina M. Knapp, BS, Kai Wang, MD PhD, Eric M. Sanford, BS, Tim Brennan, PhD, Roman Yelensky, PhD, Michelle Nahas, PhD, Geoff A Otto, PhD, Doron Lipson, PhD, Philip J Stephens, PhD, Vincent Miller, MD, Marcel R.M. van den Brink, MD, PhD, Ross L. Levine, MD, Stephen Nimer, MD, Virginia M. Klimek, M.D

Blood (2013) 122 (21): 2791.

https://doi.org/10.1182/blood.V122.21.2791.2791

Published: 2013

Journal Articles

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Ibrahim Boussaad, PhD, Andriana Kotini, PhD, Emily K Dolezal, Stephen Nimer, MD, Eirini P Papapetrou, MD, PhD

Blood (2013) 122 (21): 859.

https://doi.org/10.1182/blood.V122.21.859.859

Published: 2013

Journal Articles

Phase 2 Study of Decitabine in Combination with Tretinoin in Myelodysplastic Syndromes and Acute Myelogenous Leukemia: Interim Results

Virginia M. Klimek, M.D., Emily K Dolezal, Joseph G. Jurcic, MD, Sean Devlin, PhD, Kevin Zikaras, BS, Jae H. Park, MD, Todd L. Rosenblat, MD, Stephen Nimer, MD

Blood (2012) 120 (21): 3815.

https://doi.org/10.1182/blood.V120.21.3815.3815

Published: 2012

Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD

Blood (2012) 120 (21): 2296.

https://doi.org/10.1182/blood.V120.21.2296.2296

Published: 2012

Journal Articles

Administration of All-Trans Retinoic Acid (ATRA) to Newly Diagnosed Patients (pts) with Acute Promyelocytic Leukemia (APL) Is Delayed Even At Experienced Centers and Associated with An Increased Early Death Rate (EDR): A Retrospective Analysis of 205 Pts

Blood (2011) 118 (21): 942.

https://doi.org/10.1182/blood.V118.21.942.942

Published: 2011

Journal Articles

JAK2 V617F, PRMT5, and GATA-1 Form a Regulatory Loop That Controls Autophagy Via Effects on ATG3 Gene Expression

Michael W Harr, Ph.D., Xinyang Zhao, Ph.D., Mary Klein, Fan Liu, Ph.D., Megan Hatlen, Stephen Nimer, M.D.

Blood (2011) 118 (21): 2822.

https://doi.org/10.1182/blood.V118.21.2822.2822

Published: 2011

Journal Articles

Loss of p53 Accelerates the Complications of Myelodysplastic Syndromes (MDS) In the NUP98-HOXD13 Transgenic Mouse Model

Haiming Xu, PhD, Silvia Menendez, Tony R Deblasio, Peter Aplan, MD, Stephen Nimer, M.D.

Blood (2011) 118 (21): 2804.

https://doi.org/10.1182/blood.V118.21.2804.2804

Published: 2011

Journal Articles

Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells,

Xinyang Zhao, Ph.D., Ly P. Vu, Fabiana Perna, MD, Fan Liu, MD, Hao Xu, Stephen Nimer

Blood (2011) 118 (21): 3403.

https://doi.org/10.1182/blood.V118.21.3403.3403

Published: 2011

Journal Articles

The Acetylation of AML1-ETO Is Required for Leukemogenesis.

Lan Wang, PhD, Alexander Gural, MD, Fabiana Perna, MD, Xiaojian Sun, PhD, Xinyang Zhao, PhD, Haiming Xu, PhD, Megan A Hatlen, Gang Huang, Ph.D., Fan Liu, PhD, Hao Xu, MD, Tony Deblasio, Silvia Menendez, Francesca Voza, Robert Roeder, PhD, Stephen Nimer, MD

Blood (2010) 116 (21): 1588.

https://doi.org/10.1182/blood.V116.21.1588.1588

Published: 2010

NARROW

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Vitamin C Enhances PARPi Efficacy for the Treatment of AML

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

Mutation Profiling of Therapy-Related Myeloid Neoplasms Using Next-Generation Sequencing Demonstrates Distinct Profiles from De Novo Disease

DNA Hydroxymethylation Profiling Reveals That WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

Role of p21 in a Mouse Model of NUP98-HOXD13 Fusion Driven Myelodysplastic Syndromes (MDS)

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Comprehensive Mutational Profiling In Myelodysplastic Syndromes Treated With Decitabine and Tretinoin

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Phase 2 Study of Decitabine in Combination with Tretinoin in Myelodysplastic Syndromes and Acute Myelogenous Leukemia: Interim Results

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Administration of All-Trans Retinoic Acid (ATRA) to Newly Diagnosed Patients (pts) with Acute Promyelocytic Leukemia (APL) Is Delayed Even At Experienced Centers and Associated with An Increased Early Death Rate (EDR): A Retrospective Analysis of 205 Pts

JAK2 V617F, PRMT5, and GATA-1 Form a Regulatory Loop That Controls Autophagy Via Effects on ATG3 Gene Expression

Loss of p53 Accelerates the Complications of Myelodysplastic Syndromes (MDS) In the NUP98-HOXD13 Transgenic Mouse Model

Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells,

The Acetylation of AML1-ETO Is Required for Leukemogenesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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