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Journal Articles

Impact of Daratumumab Refractoriness on Clinical Outcomes Following CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma

Sridevi Rajeeve, Bruno Almeida Costa, Eric M Jurgens, Noriko Nishimura, Tasmin Farzana, Ross S Firestone, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Carlyn Rose Tan, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7090.
https://doi.org/10.1182/blood-2024-206511
Published: 2024
Journal Articles

Prospective Feasibility Trial of Pharmacokinetic Directed Melphalan for Lymphoma Patients Undergoing Autologous Hematopoietic Cell Transplantation

Charlotte FM Hughes, Andrew Lin, Maria Bromberg, Sean M. Devlin, Amethyst Saldia, Danielle E Engstler, Danielle M Hanley, Yetunde Aremu, Martin Donach, Elizabeth Hoover, Oscar B Lahoud, Arnab Ghosh, Moneeza Walji, Miguel-Angel Perales, Michael Scordo, Sergio A. Giralt, Gunjan L. Shah, Parastoo B Dahi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6492.
https://doi.org/10.1182/blood-2024-208310
Published: 2024
Journal Articles

Infectious Complications during Treatment with Commercial CAR T-Cell Therapy and Bispecific Antibodies for Relapsed/Refractory Multiple Myeloma

Eric M Jurgens, Tala Shekarkhand, Tasmin Farzana, Colin Rueda, David Nemirovsky, Andriy Derkach, Ross S Firestone, Noriko Nishimura, Kevin Miller, Bruno Almeida Costa, Karthik Nath, Sridevi Rajeeve, Alexander M. Lesokhin, Neha Korde, Carlyn Rose Tan, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio A. Giralt, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Saad Z. Usmani, Sham Mailankody, Zainab Shahid
Journal: Blood
Blood (2024) 144 (Supplement 1): 6935.
https://doi.org/10.1182/blood-2024-207977
Published: 2024
Journal Articles

Real-World Safety and Early Efficacy of Talquetamab in Patients with Heavily-Pretreated Relapsed/Refractory Multiple Myeloma

Bruno Almeida Costa, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7026.
https://doi.org/10.1182/blood-2024-206413
Published: 2024
Journal Articles

Defining the Rates of Cytokine Release Syndrome Associated with Talquetamab Step-up Doses

Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross S Firestone, Alice X Wang, Neha Korde, Malin Hultcrantz, Alexander M. Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A. Shah, Kylee H Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Gunjan L. Shah, Michael Scordo, David J. Chung, Heather J. Landau, Sergio A. Giralt, Saad Z. Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6990.
https://doi.org/10.1182/blood-2024-209891
Published: 2024
Journal Articles

Body Mass Index Trajectory during Triplet Induction Therapy: Clinical Implications in Newly Diagnosed Multiple Myeloma

Ram Prakash Thirugnanasambandam, Ross S Firestone, Andriy Derkach, Helena Furberg, Tala Shekarkhand, Colin Rueda, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Dhwani Patel, Oscar Boutros Lahoud, Heather J. Landau, David J. Chung, Gunjan L. Shah, Michael Scordo, Hani Hassoun, Alexander M. Lesokhin, Sergio Giralt, Neha Korde, Saad Z. Usmani, Carlyn Rose Tan, Urvi A. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 6948.
https://doi.org/10.1182/blood-2024-201845
Published: 2024
Journal Articles

Comparison of Acute Kidney Injury in Patients with Relapsed or Refractory Multiple Myeloma Following CAR T-Cell and Bispecific Antibody Therapies

Noriko Nishimura, Sham Mailankody, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Tasmin Farzana, Aisha Shaikh, Sheron Latcha, Victoria Gutgarts, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 6944.
https://doi.org/10.1182/blood-2024-212006
Published: 2024
Journal Articles

Genomic Complexity Correlates with the Degree of Marrow Independence of Malignant Plasma Cells in the Context of Extramedullary Disease

Kylee H Maclachlan, Juan-Jose Garces, Tala Shekarkhand, Sridevi Rajeeve, Hamza Hashmi, Hani Hassoun, Malin Hultcrantz, Neha Korde, Carlyn Rose Tan, Sham Mailankody, Anish Simhal, David J. Chung, Gunjan L. Shah, Michael Scordo, Sergio Giralt, Alexandra Maria Poos, Lukas John, Yanming Zhang, Robert Cimera, Maria E. Arcila, Juan E Arango Ossa, Umesh Bhanot, Mala Jain, Tala Merghoub, Heather J. Landau, Alexander M. Lesokhin, Saad Z. Usmani, Niels Weinhold, Francesco Maura, Urvi A. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 248.
https://doi.org/10.1182/blood-2024-204341
Published: 2024
Journal Articles

Comparable Outcomes of Point-of-Care and Commercial CD19 CAR-T Therapies: A Patient-Matched Analysis in Large B-Cell Lymphoma

Ronit Marcus, Abraham Avigdor, Uri Greenbaum, Noa Golan Accav, Noga Shem-Tov, Ronit Yerushalmi, Ivetta Danylesko, Elad Jacoby, Arnon Nagler, Avichai Shimoni, Annamaria Ballweg, Xavier Deschênes-Simard, Efrat Luttwak, Gunjan L. Shah, Michael Scordo, Parastoo B Dahi, Miguel Angel Perales, Tsila Zuckerman, Israel Henig, Dana Yehudai-Ofir, Hazim Khatib, Roni Shouval, Ofrat Beyar Katz
Journal: Blood
Blood (2024) 144 (Supplement 1): 608.
https://doi.org/10.1182/blood-2024-207638
Published: 2024
Journal Articles

Immune-MRD Status Informs Tumor-MRD Outcome Prognostication in Multiple Myeloma Patients on Lenalidomide Maintenance

Ross S Firestone, Anish Kumar Simhal, Devin McAvoy, Eric M Jurgens, Juan-José Garcés, David Nemirovsky, Andriy Derkach, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Urvi A. Shah, Carlyn Rose Tan, Neha Korde, Hani Hassoun, Sridevi Rajeeve, Hamza Hashmi, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Sergio Giralt, Benjamin Diamond, Francesco Maura, Kinga K. Hosszu, David J. Chung, Ola Landgren, Saad Z. Usmani, Alexander M. Lesokhin
Journal: Blood
Blood (2024) 144 (Supplement 1): 672.
https://doi.org/10.1182/blood-2024-206646
Published: 2024
Journal Articles

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

Urvi A. Shah, Laura Lucia Cogrossi, Andriy Derkach, Francesca Castro, Teng Fei, Susan DeWolf, Juan-Jose Garces, Anna Policastro, Matteo Grioni, Sofia Sisti, Blaslov Jenna, Peter Adintori, Kinga K. Hosszu, Devin McAvoy, Mirae Baichoo, Justin Cross, Aishwarya Anuraj, Charlotte Pohl, Ruben Ramos, Jenny Paredes Sanchez, Brianna Gipson, Kylee H Maclachlan, Ana Gradissimo, Leonardo Boiocchi, Richard Koche, Ronan Chaligne, Torin Block, Neha Korde, Carlyn Rose Tan, Malin Hultcrantz, Hani Hassoun, Gunjan L. Shah, Michael Scordo, Oscar B Lahoud, David J. Chung, Heather J. Landau, Jonathan U. Peled, Nicola Clementi, Marta Chesi, P. Leif Bergsagel, Sham Mailankody, Michael Pollak, Anita D'Souza, Ola Landgren, Susan Chimonas, Sergio Giralt, Saad Z. Usmani, Neil M. Iyengar, Alexander M. Lesokhin, Matteo Bellone, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 671.
https://doi.org/10.1182/blood-2024-202224
Published: 2024
Journal Articles

CAR-Tography: Longitudinal Mapping of CAR-T Toxicities across B-Cell Malignancies Reveals Biologically Distinct and Prognostically Relevant Toxicity Phenotypes

Kai Rejeski, Teng Fei, Alejandro Luna, Mohammad Alhomoud, Yannis K. Valtis, Noriko Nishimura, Marina Gomez-Llobell, Noa Golan Accav, Ofrat Beyar-Katz, Sandeep S. Raj, Magdalena Corona, Alfredo Rivas-Delgado, Hamza Hashmi, Sridevi Rajeeve, Efrat Luttwak, Michael Scordo, Gunjan L. Shah, Maria Lia Palomba, Michael von Bergwelt-Baildon, Marion Subklewe, Abraham Avigdor, Ronit Marcus, Avichai Shimoni, Arnon Nagler, Tsila Zuckerman, Jabour Halloun, Uri Greenbaum, Sham Mailankody, Saad Z. Usmani, Gilles Salles, Jae H. Park, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 912.
https://doi.org/10.1182/blood-2024-203520
Published: 2024
Journal Articles

Patterns of Immune Reconstitution and Their Clinical Significance in Aggressive Lymphoma Treated with CAR-T Therapy

Danny Luan, Susan DeWolf, Teng Fei, Sandeep S. Raj, Gunjan L. Shah, Caleb Lareau, Mohammad Alhomoud, Gilles Salles, Alfredo Rivas-Delgado, Kai Rejeski, Jae H. Park, Efrat Luttwak, Alejandro Luna, Magdalena Corona, Evangelos Ntrivalas, Giulio Cassanello, Marina Gomez-Llobell, Allison Parascondola, Michael Scordo, Katharine C. Hsu, Maria Lia Palomba, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 2034.
https://doi.org/10.1182/blood-2024-205548
Published: 2024
Journal Articles

Impact of Broad-Spectrum Antibiotic Exposure on CAR-T Therapy Outcomes in B-Cell Lymphoma: A Multicenter International Study

Roni Shouval, Teng Fei, Giulia Gabrielli, Natalie Grier Smith, Guido Ghilardi, John Slingerland, Jonathan U. Peled, Ying Taur, Sunita D. Nasta, Alejandro Luna, Magdalena Corona, Kai Rejeski, Sophia Stock, Ronit Marcus, Noa Golan Accav, Ofrat Beyar-Katz, Hazim Khatib, Sandeep S. Raj, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Jakub Svoboda, Elise A. Chong, Stefan K. Barta, Daniel J. Landsburg, Avichai Shimoni, Arnon Nagler, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Stephen J. Schuster, Tsila Zuckerman, Marion Subklewe, Abraham Avigdor, Miguel Angel Perales, Marcel R.M. van den Brink, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 1746.
https://doi.org/10.1182/blood-2024-203871
Published: 2024
Journal Articles

A Proof-of-Principle of Split-Course Bridging Radiotherapy (SC-BRT) Prior to CAR T-Cell Therapies for Relapsed or Refractory B-Cell Lymphomas: A Phase 1a Pilot Cohort

Brandon S. Imber, Anna Brosoff, Emma Roszak, Devin McAvoy, Kinga K. Hosszu, Alexander P. Boardman, Parastoo B Dahi, Gunjan L. Shah, Michael Scordo, Jae H. Park, Miguel-Angel Perales, Gilles Salles, Maria Lia Palomba, Joachim Yahalom
Journal: Blood
Blood (2024) 144 (Supplement 1): 3128.
https://doi.org/10.1182/blood-2024-210156
Published: 2024
Journal Articles

Tumor Determinants of Response to CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma

Zachary D. Epstein-Peterson, Christine E. Ryan, Sean M. Devlin, Noa Golan Accav, Abraham Avigdor, Magdalena Corona, Ivetta Danylesko, Jamie Dela Cruz, Andre Goy, Caron A. Jacobson, Ofrat Beyar Katz, Hazim Khatib, Anita Kumar, Lori A. Leslie, Alejandro Luna, Ronit Marcus, Reid W. Merryman, Miguel Angel Perales, Alfredo Rivas-Delgado, Gilles Salles, Michael Scordo, Inbal Sdayoor, Gunjan L. Shah, Noga Shem-Tov, Avichai Shimoni, Nataly Vahaba, Ronit Yerushalmi, Andrew D. Zelenetz, Maria Lia Palomba, Andrew Ip, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 4393.
https://doi.org/10.1182/blood-2024-193091
Published: 2024
Journal Articles

When Can We Define Cure after CAR-T Therapy in LBCL? Insights from Serial Landmark Analyses

Marina Gomez-Llobell, Roni Shouval, Samantha Brown, Noa Golan Accav, Sean M. Devlin, Magdalena Corona, Kai Rejeski, Alfredo Rivas-Delgado, Alejandro Luna, Efrat Luttwak, Sandeep S. Raj, Mohammad Alhomoud, Ronit Marcus, Avichai Shimoni, Shimrit Ringelstein-Harlev, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Ofrat Beyar-Katz, Abraham Avigdor, Miguel Angel Perales
Journal: Blood
Blood (2024) 144 (Supplement 1): 2369.
https://doi.org/10.1182/blood-2024-201029
Published: 2024
Journal Articles

Comparative Real-World Outcomes of Commercial CD19-Directed CAR T-Cell Therapies in Large B-Cell Lymphoma

Xavier Deschênes-Simard, Maria Bromberg, Sean M. Devlin, Ofrat Beyar Katz, Andrew Ip, Ronit Marcus, Abraham Avigdor, Annamaria Ballweg, Emma Rabinovich, Mohammad Alhomoud, Alfredo Rivas-Delgado, Magdalena Corona, Alejandro Luna De Abia, Maria Lia Palomba, Gunjan L. Shah, Richard J. Lin, Alexander P. Boardman, Lorenzo Falchi, Jennifer Kimberly Lue, Gilles Salles, Miguel-Angel Perales, Roni Shouval, Parastoo B Dahi, Michael Scordo
Journal: Blood
Blood (2024) 144 (Supplement 1): 3752.
https://doi.org/10.1182/blood-2024-211475
Published: 2024
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

Manufacture of Anti-BCMA CAR T Cell Is Feasible after Salvage Autologous or Allogeneic Hematopoietic Stem Cell Transplantation

Gunjan L. Shah, Karlo Perica, Katherine Nagel, Erica Payson, Kinga K. Hosszu, David J. Chung, Heather J. Landau, Michael Scordo, Malin Hultcrantz, Neha Korde, Kylee H Maclachlan, Urvi A. Shah, Carlyn Rose Tan, Hamza Hashmi, Alexander M. Lesokhin, Sridevi Rajeeve, Saad Z. Usmani, Sham Mailankody, Sergio A. Giralt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4850.
https://doi.org/10.1182/blood-2024-212230
Published: 2024