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Sergio Giralt
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Journal Articles

Ide-cel vs standard regimens in triple-class–exposed relapsed and refractory multiple myeloma: updated KarMMa-3 analyses

Clinical Trials & Observations
Sikander Ailawadhi, Bertrand Arnulf, Krina Patel, Michele Cavo, Ajay K. Nooka, Salomon Manier, Natalie Callander, Luciano J. Costa, Ravi Vij, Nizar J. Bahlis, Philippe Moreau, Scott Solomon, Ingerid Weum Abrahamsen, Rachid Baz, Annemiek Broijl, Christine Chen, Sundar Jagannath, Noopur Raje, Christof Scheid, Michel Delforge, Reuben Benjamin, Thomas Pabst, Shinsuke Iida, Jesús Berdeja, Sergio Giralt, Anna Truppel-Hartmann, Yanping Chen, Xiaobo Zhong, Fan Wu, Julia Piasecki, Laurie Eliason, Devender Dhanda, Jasper Felten, Andrea Caia, Mark Cook, Mihaela Popa McKiver, Paula Rodríguez-Otero
Journal: Blood
Blood (2024) 144 (23): 2389–2401.
https://doi.org/10.1182/blood.2024024582
Published: 2024
Includes: Supplemental data
Journal Articles

Impact of Daratumumab Refractoriness on Clinical Outcomes Following CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma

Sridevi Rajeeve, Bruno Almeida Costa, Eric M Jurgens, Noriko Nishimura, Tasmin Farzana, Ross S Firestone, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Carlyn Rose Tan, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7090.
https://doi.org/10.1182/blood-2024-206511
Published: 2024
Journal Articles

Real-World Safety and Early Efficacy of Talquetamab in Patients with Heavily-Pretreated Relapsed/Refractory Multiple Myeloma

Bruno Almeida Costa, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7026.
https://doi.org/10.1182/blood-2024-206413
Published: 2024
Journal Articles

Body Mass Index Trajectory during Triplet Induction Therapy: Clinical Implications in Newly Diagnosed Multiple Myeloma

Ram Prakash Thirugnanasambandam, Ross S Firestone, Andriy Derkach, Helena Furberg, Tala Shekarkhand, Colin Rueda, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Dhwani Patel, Oscar Boutros Lahoud, Heather J. Landau, David J. Chung, Gunjan L. Shah, Michael Scordo, Hani Hassoun, Alexander M. Lesokhin, Sergio Giralt, Neha Korde, Saad Z. Usmani, Carlyn Rose Tan, Urvi A. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 6948.
https://doi.org/10.1182/blood-2024-201845
Published: 2024
Journal Articles

Genomic Complexity Correlates with the Degree of Marrow Independence of Malignant Plasma Cells in the Context of Extramedullary Disease

Kylee H Maclachlan, Juan-Jose Garces, Tala Shekarkhand, Sridevi Rajeeve, Hamza Hashmi, Hani Hassoun, Malin Hultcrantz, Neha Korde, Carlyn Rose Tan, Sham Mailankody, Anish Simhal, David J. Chung, Gunjan L. Shah, Michael Scordo, Sergio Giralt, Alexandra Maria Poos, Lukas John, Yanming Zhang, Robert Cimera, Maria E. Arcila, Juan E Arango Ossa, Umesh Bhanot, Mala Jain, Tala Merghoub, Heather J. Landau, Alexander M. Lesokhin, Saad Z. Usmani, Niels Weinhold, Francesco Maura, Urvi A. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 248.
https://doi.org/10.1182/blood-2024-204341
Published: 2024
Journal Articles

Genomic Determinants of Resistance to Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) Therapies in Patients with Relapsed/Refractory Multiple Myeloma

Francesco Maura, Ciara Louise Freeman, Holly Lee, Kylee H Maclachlan, Michael Durante, Bachisio Ziccheddu, Meghan Menges, Benjamin Diamond, Marios Papadimitriou, Ariosto Siqueira Silva, Praneeth Reddy Sudalagunta, Noemie Leblay, Sungwoo Ahn, Ethan Fuller, Edward Briercheck, Phaedra Agius, Doris K. Hansen, Xiaofei Song, Xiaohong Zhao, Mark B. Meads, Jamie Teer, Ross S Firestone, Juan-Jose Garces, Tomas Jelinek, Rachid Baz, Melissa Alsina, Anusuyam Ramasubramanian, Eric Smith, Sergio Giralt, Sham Mailankody, Paola Neri, Saad Z. Usmani, Frederick Locke, Nizar J. Bahlis, Ola Landgren, Kenneth H. Shain
Journal: Blood
Blood (2024) 144 (Supplement 1): 247.
https://doi.org/10.1182/blood-2024-201288
Published: 2024
Journal Articles

Immune-MRD Status Informs Tumor-MRD Outcome Prognostication in Multiple Myeloma Patients on Lenalidomide Maintenance

Ross S Firestone, Anish Kumar Simhal, Devin McAvoy, Eric M Jurgens, Juan-José Garcés, David Nemirovsky, Andriy Derkach, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Urvi A. Shah, Carlyn Rose Tan, Neha Korde, Hani Hassoun, Sridevi Rajeeve, Hamza Hashmi, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Sergio Giralt, Benjamin Diamond, Francesco Maura, Kinga K. Hosszu, David J. Chung, Ola Landgren, Saad Z. Usmani, Alexander M. Lesokhin
Journal: Blood
Blood (2024) 144 (Supplement 1): 672.
https://doi.org/10.1182/blood-2024-206646
Published: 2024
Journal Articles

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

Urvi A. Shah, Laura Lucia Cogrossi, Andriy Derkach, Francesca Castro, Teng Fei, Susan DeWolf, Juan-Jose Garces, Anna Policastro, Matteo Grioni, Sofia Sisti, Blaslov Jenna, Peter Adintori, Kinga K. Hosszu, Devin McAvoy, Mirae Baichoo, Justin Cross, Aishwarya Anuraj, Charlotte Pohl, Ruben Ramos, Jenny Paredes Sanchez, Brianna Gipson, Kylee H Maclachlan, Ana Gradissimo, Leonardo Boiocchi, Richard Koche, Ronan Chaligne, Torin Block, Neha Korde, Carlyn Rose Tan, Malin Hultcrantz, Hani Hassoun, Gunjan L. Shah, Michael Scordo, Oscar B Lahoud, David J. Chung, Heather J. Landau, Jonathan U. Peled, Nicola Clementi, Marta Chesi, P. Leif Bergsagel, Sham Mailankody, Michael Pollak, Anita D'Souza, Ola Landgren, Susan Chimonas, Sergio Giralt, Saad Z. Usmani, Neil M. Iyengar, Alexander M. Lesokhin, Matteo Bellone, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 671.
https://doi.org/10.1182/blood-2024-202224
Published: 2024
Journal Articles

Barriers to Immune Effector Cell Therapy: Rapid Disease Progression, Concern for Toxicity, and Lack of Appropriate Trials Drive Non-Receipt after Referral at a Large Academic Center

Yannis K. Valtis, Kuo-Kai Chin, Meira Yisraeli Salman, Leora Boussi, Briana Cadzin, Carina Mcloughlin, Elizabeth Cathcart, Paul Davis, Chelsea Brooklyn, Todd Goldstein, Christopher Famulare, Gunjan L. Shah, Moneeza Walji, Alexander P. Boardman, Roni Shouval, Eytan M. Stein, Sham Mailankody, Maria Lia Palomba, Gilles Salles, Sergio Giralt, Miguel Angel Perales, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 781.
https://doi.org/10.1182/blood-2024-200915
Published: 2024
Journal Articles

Frailty and Outcomes after Bispecific T-Cell Engager Therapy for Patients with Relapsed/Refractory Multiple Myeloma

Benjamin O Adegbite, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4735.
https://doi.org/10.1182/blood-2024-201824
Published: 2024
Journal Articles

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma

Brief Report
Ross S. Firestone, Nicholas D. Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander M. Lesokhin, Hani Hassoun, Urvi Shah, Kylee H. Maclachlan, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Oscar B. Lahoud, Sergio Giralt, Kazunori Murata, Saad Z. Usmani, David J. Chung
Journal: Blood
Blood (2024) 144 (4): 402–407.
https://doi.org/10.1182/blood.2023023557
Published: 2024
Includes: Supplemental data
Journal Articles

A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract

Clinical Trials & Observations
Doris M. Ponce, Amin M. Alousi, Ryotaro Nakamura, John Slingerland, Marco Calafiore, Karamjeet S. Sandhu, Juliet N. Barker, Sean Devlin, Jinru Shia, Sergio Giralt, Miguel-Angel Perales, Gillian Moore, Samira Fatmi, Cristina Soto, Antonio Gomes, Paul Giardina, LeeAnn Marcello, Xiaoqiang Yan, Tom Tang, Kevin Dreyer, Jianmin Chen, William L. Daley, Jonathan U. Peled, Marcel R. M. van den Brink, Alan M. Hanash
Journal: Blood
Blood (2023) 141 (12): 1389–1401.
https://doi.org/10.1182/blood.2021015111
Published: 2023
Includes: Supplemental data
Journal Articles

Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy

Clinical Trials & Observations
Oliver Van Oekelen, Karthik Nath, Tarek H. Mouhieddine, Tasmin Farzana, Adolfo Aleman, David T. Melnekoff, Yogita Ghodke-Puranik, Gunjan L. Shah, Alexander Lesokhin, Sergio Giralt, Santiago Thibaud, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Joshua Richter, Shambavi Richard, Hearn J. Cho, Ajai Chari, Saad Z. Usmani, Sundar Jagannath, Urvi A. Shah, Sham Mailankody, Samir Parekh
Journal: Blood
Blood (2023) 141 (7): 756–765.
https://doi.org/10.1182/blood.2022017848
Published: 2023
Includes: Supplemental data
Journal Articles

Early intestinal microbial features are associated with CD4 T-cell recovery after allogeneic hematopoietic transplant

Clinical Trials & Observations
Oriana Miltiadous, Nicholas R. Waters, Hana Andrlová, Anqi Dai, Chi L. Nguyen, Marina Burgos da Silva, Sarah Lindner, John Slingerland, Paul Giardina, Annelie Clurman, Gabriel K. Armijo, Antonio L. C. Gomes, Madhavi Lakkaraja, Peter Maslak, Michael Scordo, Roni Shouval, Anna Staffas, Richard O’Reilly, Ying Taur, Susan Prockop, Jaap Jan Boelens, Sergio Giralt, Miguel-Angel Perales, Sean M. Devlin, Jonathan U. Peled, Kate A. Markey, Marcel R. M. van den Brink
Journal: Blood
Blood (2022) 139 (18): 2758–2769.
https://doi.org/10.1182/blood.2021014255
Published: 2022
Includes: Supplemental data
Journal Articles

Novel Agents May be Preferable to Chemotherapy for Large B-Cell Lymphoma Progressing after CD19-CAR-T: A Multicenter Observational Study

Ana Alarcon Tomas, Joshua A Fein, Shalev Fried, Warren Fingrut, Theodora Anagnostou, Anna Alperovich, Nishi Shah, Ellen Fraint, Richard J Lin, Michael Scordo, Aishat Olaide Afuye, Connie Lee Batlevi, Michal Besser, Parastoo B Dahi, Ivetta Danylesko, Sergio Giralt, Brandon S. Imber, Elad Jacobi, Arnon Nagler, M. Lia Palomba, Gilles Salles, Craig S. Sauter, Gunjan L Shah, Noga Shem-Tov, Avichai Shimoni, Joachim Yahalom, Ronit Yerushalmi, Abraham Avigdor, Miguel-Angel Perales, Roni Shouval
Journal: Blood
Blood (2021) 138 (Supplement 1): 883.
https://doi.org/10.1182/blood-2021-147568
Published: 2021
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma, a Real-World Experience

Malin Hultcrantz, Jennifer Orozco, Tim J Peterson, Andriy Derkach, Hani Hassoun, Neha Korde, Sydney X. Lu, Sham Mailankody, Dhwani Patel, Urvi A Shah, Carlyn Tan, Kylee H Maclachlan, David J. Chung, Heather J Landau, Gunjan L Shah, Oscar B Lahoud, Michael Scordo, Ola Landgren, Sergio Giralt, Alexander Lesokhin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1644.
https://doi.org/10.1182/blood-2021-153443
Published: 2021
Journal Articles

Genomic and Immune Signatures Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone (D-KRd)

Francesco Maura, Eileen M Boyle, Benjamin Diamond, Patrick Blaney, Hussein Ghamlouch, Bachisio Ziccheddu, Yubao Wang, Kylee H Maclachlan, James E. Hoffman, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Dickran Kazandjian, Gunjan L Shah, Heather J Landau, David J. Chung, Sergio Giralt, Benedetto Bruno, Yanming Zhang, Arnaldo A Arbini, Ahmet Dogan, Alexander Lesokhin, Faith E Davies, Neha Korde, Gareth J Morgan, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 325.
https://doi.org/10.1182/blood-2021-149112
Published: 2021
Journal Articles

Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study

Niloufer Khan, Sarah Lindner, Antonio L. C. Gomes, Sean M. Devlin, Gunjan L. Shah, Anthony D. Sung, Craig S. Sauter, Heather J. Landau, Parastoo B. Dahi, Miguel-Angel Perales, David J. Chung, Alexander M. Lesokhin, Anqi Dai, Annelie Clurman, John B. Slingerland, Ann E. Slingerland, Daniel G. Brereton, Paul A. Giardina, Molly Maloy, Gabriel K. Armijo, Carlos Rondon-Clavo, Emily Fontana, Lauren Bohannon, Sendhilnathan Ramalingam, Amy T. Bush, Meagan V. Lew, Julia A. Messina, Eric Littmann, Ying Taur, Robert R. Jenq, Nelson J. Chao, Sergio Giralt, Kate A. Markey, Eric G. Pamer, Marcel R. M. van den Brink, Jonathan U. Peled
Journal: Blood
Blood (2021) 137 (11): 1527–1537.
https://doi.org/10.1182/blood.2020006923
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical Outcomes of Acute Myeloid Leukemia Patients Bridged to Allogeneic Stem Cell Transplant By Venetoclax Combination Therapy

Maximilian Stahl, MD, Kamal Menghrajani, MD, Andriy Derkach, PhD, Susan DeWolf, MD, Josel D Ruiz, MPH, Doris M Ponce, MD, Brian C. Shaffer, MD, Roni Tamari, MD, James W. Young, MD, Juliet Barker, MBBS, Ann A. Jakubowski, MDPhD, Boglarka Gyurkocza, MD, Alexander Chan, Wenbin Xiao, MD PhD, Jacob L Glass, MDPhD, Amber C. King, PharmD, BCOP, Sheng F Cai, MDPhD, Anthony Daniyan, MD, Christopher Famulare, MS, Bernadette M. Cuello, BSN, MSN, NP, RN, Troy Z. Horvat, PharmD, BCOP, Eytan M. Stein, MD, Mikhail Roshal, MD PhD, Sergio Giralt, MD, Miguel-Angel Perales, MD, Christina Cho, MD, Martin S. Tallman, MD, Aaron D Goldberg, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-137749
Published: 2020
Journal Articles

Maintenance Use Is More Important Than the Choice of Bortezomib-Based Triplet Induction in Newly Diagnosed Multiple Myeloma Patients Undergoing Upfront Autologous Stem Cell Transplantation

Surbhi Sidana, MD, Shaji K. Kumar, MD, Raphael Fraser, PhD, Noel Estrada-Merly, MS, Maxim Norkin, MD PhD, Sergio Giralt, MD, Muzaffar H. Qazilbash, MD, Nina Shah, MD, Anita D'Souza, MD MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-139017
Published: 2020