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Alexander Lesokhin
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Journal Articles

Clinical Outcomes Associated with Del(17p) in Newly Diagnosed Multiple Myeloma Treated with Triplet and Daratumumab-Based Quadruplet Induction Regimens

Eric Jurgens, Ross Firestone, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Yanming Zhang, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Neha Korde, Saad Z Usmani, Carlyn Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2024.
https://doi.org/10.1182/blood-2023-190728
Published: 2023
Journal Articles

Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) and Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone (DKRd) As Induction Therapy in Newly Diagnosed Multiple Myeloma

Carlyn Tan, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Saad Z Usmani, Neha Korde
Journal: Blood
Blood (2023) 142 (Supplement 1): 4744.
https://doi.org/10.1182/blood-2023-181868
Published: 2023
Journal Articles

A Whole Foods Plant-Based Weight Loss Intervention Improves Quality of Life, Metabolic, Microbiome and Immune Profile in MGUS/SMM As Well As Progression Trajectory in a Subset - the Nutrivention Trial

Urvi A Shah, Francesca Castro, Andriy Derkach, Teng Fei, Kinga K Hosszu, Devin McAvoy, Susan DeWolf, Justin Cross, Ana Gradissimo, Alexis Nwankwo, Aishwarya Anuraj, Miranda Burge, Blaslov Jenna, Elizabeth Raynor, Jenna Wosleger, Peter Adintori, Michael Pollak, Jenny Paredes Sanchez, Thomas Atkinson, Kylee H Maclachlan, Sham Mailankody, Neha Korde, Carlyn Tan, Malin Hultcrantz, Hani Hassoun, Jonathan U. Peled, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Anita D'Souza, Ola Landgren, Sergio A. Giralt, Neil M. Iyengar, Saad Z Usmani, Alexander Lesokhin, Marcel R.M. van den Brink
Journal: Blood
Blood (2023) 142 (Supplement 1): 4771.
https://doi.org/10.1182/blood-2023-182878
Published: 2023
Journal Articles

Long-Term Efficacy and Safety of Elranatamab Monotherapy in the Phase 2 Magnetismm-3 Trial in Relapsed or Refractory Multiple Myeloma (RRMM)

Michael Tomasson, Shinsuke Iida, Ruben Niesvizky, Mohamad Mohty, Nizar J Bahlis, Joaquin Martinez-Lopez, Guenther Koehne, Paula Rodriguez Otero, H. Miles Prince, Andrea Viqueira, Eric Leip, Umberto Conte, Sharon T Sullivan, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3385.
https://doi.org/10.1182/blood-2023-182130
Published: 2023
Journal Articles

Dose Escalation of ISB 1342, a Novel CD38xCD3 Bispecific Antibody, in Patients with Relapsed / Refractory Multiple Myeloma (RRMM)

Prashant Kapoor, Don A. Stevens, Xavier Leleu, Karim Belhadj Merzoug, Lionel Karlin, Salomon Manier, Thomas Chalopin, Cyrille Hulin, Aurore Perrot, Jésus G Berdeja, Cristiana Costa Chase, Cyrille Touzeau, Philippe Moreau, Sanjay Mohan, Alexander Lesokhin, Carol Huff, David H. Vesole, Joshua Richter, Jeffrey Matous, Eileen Wolff, Tejas Shah, Jeppe Koch-Olsen, Andrew Garton, Vinu Menon, Sunitha Gn, Mario Perro, Eugene Zhukovsky, Cyril Konto, Lida Pacaud, Mohamad Mohty
Journal: Blood
Blood (2023) 142 (Supplement 1): 3339.
https://doi.org/10.1182/blood-2023-186664
Published: 2023
Journal Articles

Stem Cell Utilization in the Era of Novel Therapies for Multiple Myeloma

Noriko Nishimura, David Nemirovsky, Sean M. Devlin, Parastoo B. Dahi, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Sham Mailankody, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander Lesokhin, Urvi A Shah, Carlyn Tan, Gaurav Gupta, Elena Maryamchik, Rugved Pattarkine, Grace Linder, Saad Z Usmani, Sergio A. Giralt, David Chung
Journal: Blood
Blood (2023) 142 (Supplement 1): 2219.
https://doi.org/10.1182/blood-2023-188103
Published: 2023
Journal Articles

The Complex Structural Variant Chromothripsis Can be Defined on Targeted Sequencing Panels, Allowing Direct Clinical Translation in Order to Improve Multiple Myeloma Prognostication

Kylee H Maclachlan, Bachisio Ziccheddu, Carlyn Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, Benjamin Diamond, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ola Landgren, Alexander Lesokhin, Neha Korde, Francesco Maura, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3343.
https://doi.org/10.1182/blood-2023-189316
Published: 2023
Journal Articles

Revealing Novel Mechanisms Underlying Inactivation of Tumor Suppressor Genes on Duplicated Chromosomes in Multiple Myeloma

Anthony Cirrincione, Marcella Kaddoura, Alexandra Maria Poos, Bachisio Ziccheddu, Kylee H Maclachlan, Monika Chojnacka, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander Lesokhin, Faith E. Davies, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Elias K. Mai, Neha Korde, Gareth J. Morgan, Marc S. Raab, Saad Z Usmani, Ola Landgren, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2023) 142 (Supplement 1): 874.
https://doi.org/10.1182/blood-2023-186802
Published: 2023
Journal Articles

Comprehensive Genomic Characterization of Response and Resistance to Daratumumab-Based Quadruplet Induction in Newly Diagnosed Multiple Myeloma Patients

Kylee H Maclachlan, Carlyn Rose Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, David Nemirovsky, Andriy Derkach, Andrew McPherson, Benjamin Diamond, Bachisio Ziccheddu, Eileen Boyle, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ahmet Dogan, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura, Neha Korde, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2023-187891
Published: 2023
Journal Articles

T-Cell Exhaustion Signature Predicts Early Relapse after Autologous Stem Cell Transplant for Multiple Myeloma: BMT CTN 0702 Secondary Immune Analysis

Nezar Mehanna, Andriy Derkach, Billel Gasmi, Theodora Anagnostou, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Sham Mailankody, Urvi A Shah, Carlyn Rose Tan, Saad Z Usmani, Sergio A. Giralt, Alexander Lesokhin, David Chung
Journal: Blood
Blood (2023) 142 (Supplement 1): 3326.
https://doi.org/10.1182/blood-2023-177960
Published: 2023
Journal Articles

Dietary Patterns Among Individuals with Plasma Cell Disorders Compared to the General US Population

Kadiatou Traore, Alankrita Taneja, Elan Gorshein, Francesca Castro, Andriy Derkach, Jorge Arturo Hurtado Martinez, Edith Serrano, Alexander Lesokhin, Jennifer M. Ahlstrom, Torin Block, Jay R. Hydren, Saad Z Usmani, Urvi A Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 7363.
https://doi.org/10.1182/blood-2023-186913
Published: 2023
Journal Articles

Patterns of Cytokine Release Syndrome with Teclistamab in Relapsed/Refractory Multiple Myeloma with or without Prior T-Cell Redirection Therapy

Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross Firestone, Alice Wang, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A Shah, Kylee H Maclachlan, Dhwani Patel, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Sergio A. Giralt, Saad Z Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1961.
https://doi.org/10.1182/blood-2023-180283
Published: 2023
Journal Articles

Evaluating the Effect of Evolving Changes in Serum Biomarkers on the Risk of Progression in Smoldering Multiple Myeloma

Theresia Akhlaghi, David Nemirovsky, Kylee H Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Dhwani Patel, Urvi A Shah, Carlyn Tan, Oscar Boutros Lahoud, Heather Landau, Gunjan L. Shah, Michael Scordo, David Chung, Ola Landgren, Sergio A. Giralt, Saad Z Usmani, Andriy Derkach, Malin Hultcrantz
Journal: Blood
Blood (2023) 142 (Supplement 1): 877.
https://doi.org/10.1182/blood-2023-180315
Published: 2023
Journal Articles

Evaluating Tumor-Intrinsic and Patient-Specific Mechanisms of Resistance to Teclistamab in Anti-BCMA Exposed and Naïve Multiple Myeloma

Ross Firestone, Devin McAvoy, Tala Shekarkhand, Edith Serrano, Issam S. Hamadeh, Alice Wang, Menglei Zhu, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, Kinga K Hosszu, David Chung, Alexander Lesokhin, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 333.
https://doi.org/10.1182/blood-2023-187467
Published: 2023
Journal Articles

Identifying Causes of Unscheduled Healthcare Interactions and Changes to Patient Disposition in Individuals Receiving Outpatient Commercial Bispecific Antibody Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Anna J Howard, Tala Shekarkhand, Issam S. Hamadeh, Alice Wang, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, David Chung, Alexander Lesokhin, Saad Z Usmani, Ross Firestone
Journal: Blood
Blood (2023) 142 (Supplement 1): 3707.
https://doi.org/10.1182/blood-2023-187889
Published: 2023
Journal Articles

Clinical Factors Associated with Cytokine Release Syndrome and Dosing Recommendations for Restarting Elranatamab Following an Interruption

Ruben Niesvizky, Bertrand Arnulf, Mohamad Mohty, Ajay K. Nooka, Salomon Manier, Michael Tomasson, Nizar J Bahlis, Donald Irby, Jennifer Hibma, Andrea Viqueira, Eric Leip, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3384.
https://doi.org/10.1182/blood-2023-182166
Published: 2023
Journal Articles

A Comparative Analysis of Infectious Complications in Patients with Multiple Myeloma Treated with BCMA-Targeted Bispecific Antibodies and CAR T-Cell Therapy

Karthik Nath, Tala Shekarkhand, Bruno Almeida Costa, David Nemirovsky, Andriy Derkach, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Kylee H Maclachlan, Neha Korde, Urvi A Shah, Carlyn Rose Tan, Malin Hultcrantz, Sergio A. Giralt, Saad Z Usmani, Zainab Shahid, Sham Mailankody, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2023-179413
Published: 2023
Journal Articles

Efficacy and Safety of Elranatamab in Black Patients with Relapsed/Refractory Multiple Myeloma (RRMM): A Subgroup Analysis of the Magnetismm Studies

Asya Varshavsky-Yanovsky, Yogesh Jethava, Don A. Stevens, Ajay K. Nooka, Patrick J. Stiff, Isabel Perez-Cruz, Eric Leip, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2023-181951
Published: 2023
Journal Articles

Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Therapy in High-Risk Newly Diagnosed Multiple Myeloma

Carlyn Tan, Neha Korde, Andriy Derkach, Malin Hultcrantz, Kylee H Maclachlan, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Alexander Lesokhin, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Craig C. Hofmeister, Jonathan L. Kaufman, Ajay K. Nooka, Saad Z Usmani, Sagar Lonial, Nisha S. Joseph
Journal: Blood
Blood (2023) 142 (Supplement 1): 1996.
https://doi.org/10.1182/blood-2023-190279
Published: 2023
Journal Articles

Whole-Genome Sequencing Reveals Distinct Mutational Signatures in Multiple Myeloma Patients with African Ancestry Compared with Those of Non-African Ancestry

Kylee H Maclachlan, Patrick Blaney, Anthony Cirrincione, Timothy R. Chu, Alexandra Maria Poos, Elizabeth E. Brown, Elisabet E. Manasanch, Antje Hoering, Liming Hou, Dylan Gagler, Yubao Wang, Sanxiong Liu, Benjamin Diamond, Bachisio Ziccheddu, Marc S. Raab, Niels Weinhold, Ola Landgren, Nicolas Robine, Faith E. Davies, Alexander Lesokhin, Saad Z Usmani, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2023-190882
Published: 2023