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Karthik Nath
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Journal Articles

Infectious Complications during Treatment with Commercial CAR T-Cell Therapy and Bispecific Antibodies for Relapsed/Refractory Multiple Myeloma

Eric M Jurgens, Tala Shekarkhand, Tasmin Farzana, Colin Rueda, David Nemirovsky, Andriy Derkach, Ross S Firestone, Noriko Nishimura, Kevin Miller, Bruno Almeida Costa, Karthik Nath, Sridevi Rajeeve, Alexander M. Lesokhin, Neha Korde, Carlyn Rose Tan, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio A. Giralt, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Saad Z. Usmani, Sham Mailankody, Zainab Shahid
Journal: Blood
Blood (2024) 144 (Supplement 1): 6935.
https://doi.org/10.1182/blood-2024-207977
Published: 2024
Journal Articles

Comparison of Acute Kidney Injury in Patients with Relapsed or Refractory Multiple Myeloma Following CAR T-Cell and Bispecific Antibody Therapies

Noriko Nishimura, Sham Mailankody, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Tasmin Farzana, Aisha Shaikh, Sheron Latcha, Victoria Gutgarts, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 6944.
https://doi.org/10.1182/blood-2024-212006
Published: 2024
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

A Phase II Trial of Prophylactic Anakinra to Prevent Neurotoxicity in Patients Receiving Anti-CD19 CAR T-Cell Therapy for Relapsed or Refractory Lymphoma: Final Results from Cohort 2

Karthik Nath, Sean M. Devlin, Craig S Sauter, Maria Lia Palomba, Gunjan L. Shah, Parastoo Bahrami Dahi, Richard J. Lin, Michael Scordo, Miguel-Angel Perales, Lori A. Leslie, Roni Shouval, Sara Bekele, Elizabeth Cathcart, Elena Mead, Bianca Santomasso, Andrei Holodny, Renier Brentjens, Isabelle Riviere, Michel Sadelain, Jae H. Park
Journal: Blood
Blood (2023) 142 (Supplement 1): 357.
https://doi.org/10.1182/blood-2023-174728
Published: 2023
Journal Articles

Comparison of Bendamustine Versus Fludarabine/ Cyclophosphamide Lymphodepletion in Adult Patients Receiving CD19 CAR-T Cell Therapy

Ivan Landego, David Nemirovsky, Sean M. Devlin, Beatriz Wills, Allison Parascondola, Amethyst Saldia, Parastoo B. Dahi, Ana Alarcon Tomas, Andrew Ip, Hyung C Suh, Lori A. Leslie, Karthik Nath, Sergio A. Giralt, Richard J. Lin, Maria Lia Palomba, Gilles Salles, Gunjan L. Shah, Roni Shouval, Miguel-Angel Perales, Michael Scordo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3510.
https://doi.org/10.1182/blood-2023-189349
Published: 2023
Journal Articles

A Comparative Analysis of Infectious Complications in Patients with Multiple Myeloma Treated with BCMA-Targeted Bispecific Antibodies and CAR T-Cell Therapy

Karthik Nath, Tala Shekarkhand, Bruno Almeida Costa, David Nemirovsky, Andriy Derkach, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Kylee H Maclachlan, Neha Korde, Urvi A Shah, Carlyn Rose Tan, Malin Hultcrantz, Sergio A. Giralt, Saad Z Usmani, Zainab Shahid, Sham Mailankody, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2023-179413
Published: 2023
Journal Articles

Demographic Disparities in Clinical Trial Enrollment of US Patients with Newly-Diagnosed Multiple Myeloma

Bruno Almeida Costa, Neha Debnath, Thomaz Alexandre Costa, Raphael Bertasi, Tarek H. Mouhieddine, Karthik Nath, Adriana C Rossi
Journal: Blood
Blood (2023) 142 (Supplement 1): 7371.
https://doi.org/10.1182/blood-2023-190861
Published: 2023
Journal Articles

Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy

Clinical Trials & Observations
Oliver Van Oekelen, Karthik Nath, Tarek H. Mouhieddine, Tasmin Farzana, Adolfo Aleman, David T. Melnekoff, Yogita Ghodke-Puranik, Gunjan L. Shah, Alexander Lesokhin, Sergio Giralt, Santiago Thibaud, Adriana Rossi, Cesar Rodriguez, Larysa Sanchez, Joshua Richter, Shambavi Richard, Hearn J. Cho, Ajai Chari, Saad Z. Usmani, Sundar Jagannath, Urvi A. Shah, Sham Mailankody, Samir Parekh
Journal: Blood
Blood (2023) 141 (7): 756–765.
https://doi.org/10.1182/blood.2022017848
Published: 2023
Includes: Supplemental data
Journal Articles

Prospective Analysis to Determine Barriers to Allogeneic Hematopoietic Cell Transplantation in Patients with Newly Diagnosed and Relapsed Acute Leukemia

Karthik Nath, Jasme Lee, Theresa A Elko, Lauren Levy, Elaina Preston, Sean M. Devlin, Doris M Ponce, Richard J. Lin, Brian C. Shaffer, Christina Cho, Ioannis Politikos, Ann A Jakubowski, Jae H Park, Raajit Rampal, Miguel-Angel Perales, Martin S. Tallman, Juliet N. Barker, Sergio A Giralt, Ellin Berman, Roni Tamari, Eytan Stein, Boglarka Gyurkocza
Journal: Blood
Blood (2022) 140 (Supplement 1): 2137–2139.
https://doi.org/10.1182/blood-2022-157193
Published: 2022
Journal Articles

Severe Persistent Cytopenias Following CAR T-Cell Therapy in Patients with Large B-Cell Lymphoma

Magdalena Corona De Lapuerta, Roni Shouval, Ana Alarcon Tomas, Jessica R. Flynn, Sean M. Devlin, Connie Lee Batlevi, Joshua A Fein, Sergio A Giralt, Richard J. Lin, Karthik Nath, Maria Lia Palomba, Allison Parascondola, Gunjan L. Shah, Gilles Salles, Michael Scordo, Moneeza Walji, Miguel-Angel Perales, Parastoo B Dahi
Journal: Blood
Blood (2022) 140 (Supplement 1): 12770–12772.
https://doi.org/10.1182/blood-2022-163457
Published: 2022
Journal Articles

Inflammatory Biomarker Clusters Are Predictive of Response and Toxicity in Large B-Cell Lymphoma Treated with CD19 CAR-T Cell Therapy

Sandeep Raj, Miguel-Angel Perales, Joshua A Fein, Ana Alarcon Tomas, Connie Lee Batlevi, Magdalena Corona De Lapuerta, Parastoo B Dahi, Ivetta Danylesko, Shalev Fried, Tyler Funnell, Sergio A. Giralt, Elad Jacoby, Meirav Kedmi, Richard J. Lin, Arnon Nagler, Karthik Nath, Allison Parascondola, M.Lia Palomba, Gilles Salles, Michael Scordo, Gunjan L. Shah, Noga Shem-Tov, Avichai Shimoni, John Slingerland, Moneeza Walji, Ronit Yerushalmi, Abraham Avigdor, Marcel R M van den Brink, Roni Shouval
Journal: Blood
Blood (2022) 140 (Supplement 1): 648–650.
https://doi.org/10.1182/blood-2022-162286
Published: 2022
Journal Articles

Predictors and Implications of Renal Injury in Large Cell Lymphoma Patients Receiving CD19 CAR T Cell Therapy

Alexander P. Boardman, Victoria Gutgarts, Jessica R. Flynn, Sean M. Devlin, Ana Alarcon Tomas, Joshua A. Fein, John Slingerland, Allison Parascondola, Richard J. Lin, Michael Scordo, Connie Lee Batlevi, Parastoo B. Dahi, Sergio A. Giralt, M.Lia Palomba, Gilles Salles, Karthik Nath, Moneeza Walji, Magdalena Corona De Lapuerta, Gunjan L. Shah, Miguel-Angel Perales, Insara Jaffer-Sathick, Roni Shouval
Journal: Blood
Blood (2022) 140 (Supplement 1): 4671–4672.
https://doi.org/10.1182/blood-2022-157455
Published: 2022
Journal Articles

The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma

Jay Gunawardana, Muhammed B. Sabdia, Karolina Bednarska, Soi C. Law, Sandra Brosda, Hennes Tsang, Lilia Merida De Long, Andreea Zaharia, Justina Lee, Emily Jude, Eliza Hawkes, Karthik Nath, Clare Gould, Melinda Lea Burgess, Fiona Swain, Joshua W.D. Tobin, Colm Keane, Simone Birch, Dipti Talaulikar, Sanjiv Jain, Mohamed Shanavas, Cameron Snell, Maher Gandhi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3513.
https://doi.org/10.1182/blood-2021-145840
Published: 2021
Journal Articles

Neoantigens Are Typically Associated with Intact HLA Class I Presentation in Early-Stage Follicular Lymphoma

Hennes Tsang, BSc, Ann-Marie Patch, PhD, Colm Keane, MD, Soi C. Law, PhD, Jay Gunawardana, PhD, Piers Blombery, MBBS, Ella R Thompson, PhD BSc, Muhammed B. Sabdia, Lilia Merida De Long, Clemence J Belle, Karthik Nath, MBBS, Joshua W.D. Tobin, MD, Stephen H Kazakoff, PhD, John F. Seymour, Michael MacManus, Maher K. Gandhi, PhDFRACP,FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-135954
Published: 2020
Journal Articles

Intra-Tumoral CD8+ T-Cells in Follicular Lymphoma Contain Large Clonal Expansions That Are Amenable to Dual-Checkpoint Blockade

Karthik Nath, MBBS, Soi C. Law, Muhammed B. Sabdia, Lilia Merida De Long, Mohamed Shanavas, MD, Joshua W.D. Tobin, MD, Jay Gunawardana, PhD, Frank Vari, PhD, Sarah-Jane Halliday, Annette Hernandez, BS, Donna Cross, Robert J. Bird, FRACP,FRCP,FRCPA,MBBS,MRCP, Colm Keane, MD, Maher K. Gandhi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2793.
https://doi.org/10.1182/blood-2019-130050
Published: 2019