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Roni Shouval
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Journal Articles

Development of ALL-Hematotox (ALL-HT): Predicting post CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Monica S Nair, Sara K Silbert, Kai Rejeski, Karilynn A Wilson, Adam Joseph Lamble, Yannis K. Valtis, Bonnie Yates, Alexa Morales Arana, Roni Shouval, Kevin J. Curran, Rebecca A Gardner, Haneen Shalabi, Colleen Annesley, Jae H. Park, Marion Subklewe, Nirali N Shah
Journal: Blood
Blood blood.2024025910.
https://doi.org/10.1182/blood.2024025910
Published: 2024
Includes: Supplemental data
Journal Articles

When Can We Define Cure after CAR-T Therapy in LBCL? Insights from Serial Landmark Analyses

Marina Gomez-Llobell, Roni Shouval, Samantha Brown, Noa Golan Accav, Sean M. Devlin, Magdalena Corona, Kai Rejeski, Alfredo Rivas-Delgado, Alejandro Luna, Efrat Luttwak, Sandeep S. Raj, Mohammad Alhomoud, Ronit Marcus, Avichai Shimoni, Shimrit Ringelstein-Harlev, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Ofrat Beyar-Katz, Abraham Avigdor, Miguel Angel Perales
Journal: Blood
Blood (2024) 144 (Supplement 1): 2369.
https://doi.org/10.1182/blood-2024-201029
Published: 2024
Journal Articles

Comparative Real-World Outcomes of Commercial CD19-Directed CAR T-Cell Therapies in Large B-Cell Lymphoma

Xavier Deschênes-Simard, Maria Bromberg, Sean M. Devlin, Ofrat Beyar Katz, Andrew Ip, Ronit Marcus, Abraham Avigdor, Annamaria Ballweg, Emma Rabinovich, Mohammad Alhomoud, Alfredo Rivas-Delgado, Magdalena Corona, Alejandro Luna De Abia, Maria Lia Palomba, Gunjan L. Shah, Richard J. Lin, Alexander P. Boardman, Lorenzo Falchi, Jennifer Kimberly Lue, Gilles Salles, Miguel-Angel Perales, Roni Shouval, Parastoo B Dahi, Michael Scordo
Journal: Blood
Blood (2024) 144 (Supplement 1): 3752.
https://doi.org/10.1182/blood-2024-211475
Published: 2024
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

Tumor Determinants of Response to CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma

Zachary D. Epstein-Peterson, Christine E. Ryan, Sean M. Devlin, Noa Golan Accav, Abraham Avigdor, Magdalena Corona, Ivetta Danylesko, Jamie Dela Cruz, Andre Goy, Caron A. Jacobson, Ofrat Beyar Katz, Hazim Khatib, Anita Kumar, Lori A. Leslie, Alejandro Luna, Ronit Marcus, Reid W. Merryman, Miguel Angel Perales, Alfredo Rivas-Delgado, Gilles Salles, Michael Scordo, Inbal Sdayoor, Gunjan L. Shah, Noga Shem-Tov, Avichai Shimoni, Nataly Vahaba, Ronit Yerushalmi, Andrew D. Zelenetz, Maria Lia Palomba, Andrew Ip, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 4393.
https://doi.org/10.1182/blood-2024-193091
Published: 2024
Journal Articles

Predictors of Early Safety Outcomes with Axicabtagene Ciloleucel (axi-cel) in Patients with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Christopher Strouse, Umar Farooq, Roni Shouval, Anusha Vallurupalli, Amy Moskop, Caron A. Jacobson, Frederick Locke, John H. Baird, Paolo Strati, Dilan A. Patel, Saurabh Dahiya, Michael T. Hemmer, Brad Du, Clare Spooner, Jenny J. Kim, Debbie L. Mirjah, Zhen-Huan Hu, Marcelo C. Pasquini, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 609.
https://doi.org/10.1182/blood-2024-207976
Published: 2024
Journal Articles

Comparable Outcomes of Point-of-Care and Commercial CD19 CAR-T Therapies: A Patient-Matched Analysis in Large B-Cell Lymphoma

Ronit Marcus, Abraham Avigdor, Uri Greenbaum, Noa Golan Accav, Noga Shem-Tov, Ronit Yerushalmi, Ivetta Danylesko, Elad Jacoby, Arnon Nagler, Avichai Shimoni, Annamaria Ballweg, Xavier Deschênes-Simard, Efrat Luttwak, Gunjan L. Shah, Michael Scordo, Parastoo B Dahi, Miguel Angel Perales, Tsila Zuckerman, Israel Henig, Dana Yehudai-Ofir, Hazim Khatib, Roni Shouval, Ofrat Beyar Katz
Journal: Blood
Blood (2024) 144 (Supplement 1): 608.
https://doi.org/10.1182/blood-2024-207638
Published: 2024
Journal Articles

Inflammation-Based Scores Predict Survival after CD3xCD20 Bispecific T Cell Engagers in R/R LBCL

Giulia Magno, Kai Rejeski, Giulia Rappa, Sissi Kupf, Sophia Stock, Alessandra M. E. Holzem, Julia Katharina Scholz, Rebecca Wurm-Kuczera, Shimrit Harlev, Nadine Kutsch, Giuliano Filippini Velazquez, Stephanie Mayer, Maria Landwehr, Jamila Mammadova, Sandeep S. Raj, Roni Shouval, Fabian Mueller, Björn Chapuy, Ofrat Beyar-Katz, Udo Holtick, Christoph Schmidt, Hendrik Poeck, Gloria Iacoboni, Pere Barba, Ning Dong, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 1714.
https://doi.org/10.1182/blood-2024-211459
Published: 2024
Journal Articles

Reduction in Platelet Counts May Predict the Development of Immune Effector Cell Associated Neurotoxicity Syndrome in Patients Receiving CD19 CAR-T Cell Therapy for Relapsed/Refractory Large B Cell Lymphoma

Hazim Khatib, Amit Parizat, Jabour Halloun, Roni Shouval, Niveen Shibli, Onit Alalouf, Tsila Zuckerman, Nataly Vahaba, Iris Halamish, Danielle Sapir, Israel Henig, Dana Yehudai-Ofir, Shimrit Harlev, Netanel A. Horowitz, Noa Lavi, Nurit Horesh, Riva Fineman, Inna Tzoran, Tsofia Levi, Eldad J. Dann, Ahmad Mruwat, Benjamin Brenner, Ron Hoffman, Ayal Rozenberg, Yoav Shechtman, Ofrat Beyar-Katz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1748.
https://doi.org/10.1182/blood-2024-202937
Published: 2024
Journal Articles

Impact of Broad-Spectrum Antibiotic Exposure on CAR-T Therapy Outcomes in B-Cell Lymphoma: A Multicenter International Study

Roni Shouval, Teng Fei, Giulia Gabrielli, Natalie Grier Smith, Guido Ghilardi, John Slingerland, Jonathan U. Peled, Ying Taur, Sunita D. Nasta, Alejandro Luna, Magdalena Corona, Kai Rejeski, Sophia Stock, Ronit Marcus, Noa Golan Accav, Ofrat Beyar-Katz, Hazim Khatib, Sandeep S. Raj, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Jakub Svoboda, Elise A. Chong, Stefan K. Barta, Daniel J. Landsburg, Avichai Shimoni, Arnon Nagler, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Stephen J. Schuster, Tsila Zuckerman, Marion Subklewe, Abraham Avigdor, Miguel Angel Perales, Marcel R.M. van den Brink, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 1746.
https://doi.org/10.1182/blood-2024-203871
Published: 2024
Journal Articles

CAR T-Cell Therapy for DLBCL with CNS Involvement: Overall Safe and Effective with Limited Efficacy in Patients with Leptomeningeal Disease

Efrat Luttwak, Giulio Cassanello, Samantha Brown, Sean M. Devlin, Brandon S. Imber, Andrew Ip, Lori A. Leslie, Noa Golan Accav, Ofrat Beyar-Katz, Magdalena Corona, Alejandro Luna De Abia, Alfredo Rivas-Delgado, Jennifer Kimberly Lue, Christian Grommes, Gunjan L. Shah, Jae H. Park, Miguel Angel Perales, Gilles Salles, Roni Shouval, Maria Lia Palomba, Michael Scordo
Journal: Blood
Blood (2024) 144 (Supplement 1): 4509.
https://doi.org/10.1182/blood-2024-212274
Published: 2024
Journal Articles

CD19 CAR-T Cell Therapy Is Effective in Richter Transformation: A Multicenter Retrospective Analysis By the European Research Initiative on Chronic Lymphocytic Leukemia

Ofrat Beyar-Katz, Ohad Benjamini, Julio Delgado, Marco Ruella, Ron Ram, Sigal Grisariu, Andrea Visentin, Elisabeth Vandenberghe, Massimo Gentile, Abraham Avigdor, Avichai Shimoni, Roni Shouval, Ronit Marcus, Stephen J. Schuster, Valentin Ortiz-Maldonado, Guido Ghilardi, Luca Paruzzo, Tsila Zuckerman, Tamar Tadmor, Riva Fineman, Odelia Amit, Nuria Martinez-Cibrian, Giulia Gabrielli, Batia Avni, Eva Minga, Noga Shem-Tov, Lydia Scarfo, Ronit Yerushalmi, Arnon Nagler, Ronit Leiba, Ivetta Danylesko, Kostas Stamatopoulos, Thomas Chatzikonstantinou, Paolo Ghia, Yair Herishanu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4504.
https://doi.org/10.1182/blood-2024-200050
Published: 2024
Journal Articles

Bridging Radiotherapy May Decrease Inflammation Prior to CAR-T Cell Therapy

Roshal R. Patel, Alexander Tward, Beatrice Fregonese, Harper Hubbeling, Kaitlyn Lapen, Nikhil P. Mankuzhy, Sandeep S. Raj, Miguel-Angel Perales, Roni Shouval, Joachim Yahalom, Brandon S. Imber
Journal: Blood
Blood (2024) 144 (Supplement 1): 7164.
https://doi.org/10.1182/blood-2024-210814
Published: 2024
Journal Articles

Pre-Apheresis Prediction of Toxicity and Response in Patients Receiving BCMA-Directed CAR-T for Relapsed/Refractory Multiple Myeloma

Kai Rejeski, Doris K. Hansen, David M. Cordas Dos Santos, Andre De Menezes Silva Corraes, Omar Castaneda, Christen M Dillard, Winfried Alsdorf, Jan H. Frenking, Anna Purcarea, Saurabh Chhabra, Ciara Louise Freeman, Mirco Julian Friedrich, Mahmoud R. Gaballa, Rebecca Gonzalez, Syed Hamza Bin Waqar, Yi Lisa Hwa, Michael D. Jain, Ricardo D. Parrondo, Oren Pasvolsky, Wajma Shahbaz, Roni Shouval, Genevieve Spiess, Haily Stephens, Sebastian Theurich, Florian Bassermann, Judith S. Hecker, Marc S. Raab, Katja C. Weisel, Frederick L. Locke, Marion Subklewe, Krina K. Patel, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 895.
https://doi.org/10.1182/blood-2024-208376
Published: 2024
Journal Articles

Treatment Patterns and Outcomes Following Progression of Disease Post-CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter Analysis

Zachary D. Epstein-Peterson, Anath C. Lionel, Ashlee Joseph, Esther Drill, Suheil Albert Atallah-Yunes, Taylor R. Brooks, Elise A. Chong, Emeline R. Chong, Jamie Dela Cruz, Matthew J. Frank, Andrew Ip, Madiha Iqbal, Caron A. Jacobson, Manali K. Kamdar, Reem Karmali, Kami J. Maddocks, Matthew Matasar, Reid W. Merryman, Javier Munoz, Peter A. Riedell, Christine E. Ryan, Gilles Salles, Craig S. Sauter, Yazeed Sawalha, Roni Shouval, Navika Shukla, Alexander V. Stanisic, Dylan Therwhanger, Herman Van Besien, Yucai Wang, Samuel Yamshon, Andrew D. Zelenetz, Maria Lia Palomba, Preetesh Jain, Anita Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 238.
https://doi.org/10.1182/blood-2024-192995
Published: 2024
Journal Articles

Barriers to Immune Effector Cell Therapy: Rapid Disease Progression, Concern for Toxicity, and Lack of Appropriate Trials Drive Non-Receipt after Referral at a Large Academic Center

Yannis K. Valtis, Kuo-Kai Chin, Meira Yisraeli Salman, Leora Boussi, Briana Cadzin, Carina Mcloughlin, Elizabeth Cathcart, Paul Davis, Chelsea Brooklyn, Todd Goldstein, Christopher Famulare, Gunjan L. Shah, Moneeza Walji, Alexander P. Boardman, Roni Shouval, Eytan M. Stein, Sham Mailankody, Maria Lia Palomba, Gilles Salles, Sergio Giralt, Miguel Angel Perales, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 781.
https://doi.org/10.1182/blood-2024-200915
Published: 2024
Journal Articles

Comparison of Acute Kidney Injury in Patients with Relapsed or Refractory Multiple Myeloma Following CAR T-Cell and Bispecific Antibody Therapies

Noriko Nishimura, Sham Mailankody, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Tasmin Farzana, Aisha Shaikh, Sheron Latcha, Victoria Gutgarts, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 6944.
https://doi.org/10.1182/blood-2024-212006
Published: 2024
Journal Articles

CAR-Tography: Longitudinal Mapping of CAR-T Toxicities across B-Cell Malignancies Reveals Biologically Distinct and Prognostically Relevant Toxicity Phenotypes

Kai Rejeski, Teng Fei, Alejandro Luna, Mohammad Alhomoud, Yannis K. Valtis, Noriko Nishimura, Marina Gomez-Llobell, Noa Golan Accav, Ofrat Beyar-Katz, Sandeep S. Raj, Magdalena Corona, Alfredo Rivas-Delgado, Hamza Hashmi, Sridevi Rajeeve, Efrat Luttwak, Michael Scordo, Gunjan L. Shah, Maria Lia Palomba, Michael von Bergwelt-Baildon, Marion Subklewe, Abraham Avigdor, Ronit Marcus, Avichai Shimoni, Arnon Nagler, Tsila Zuckerman, Jabour Halloun, Uri Greenbaum, Sham Mailankody, Saad Z. Usmani, Gilles Salles, Jae H. Park, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 912.
https://doi.org/10.1182/blood-2024-203520
Published: 2024
Journal Articles

Patterns of Immune Reconstitution and Their Clinical Significance in Aggressive Lymphoma Treated with CAR-T Therapy

Danny Luan, Susan DeWolf, Teng Fei, Sandeep S. Raj, Gunjan L. Shah, Caleb Lareau, Mohammad Alhomoud, Gilles Salles, Alfredo Rivas-Delgado, Kai Rejeski, Jae H. Park, Efrat Luttwak, Alejandro Luna, Magdalena Corona, Evangelos Ntrivalas, Giulio Cassanello, Marina Gomez-Llobell, Allison Parascondola, Michael Scordo, Katharine C. Hsu, Maria Lia Palomba, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 2034.
https://doi.org/10.1182/blood-2024-205548
Published: 2024
Journal Articles

From Widespread to Tailored Antifungal Prophylaxis in Lymphoma Patients Treated with CD19 CAR T- Cell Therapy: Less Is Better

Giovanna Melica, Alejandro Luna De Abia, Magdalena Corona, Joshua Fein, Parastoo B Dahi, Sergio A. Giralt, Ivan Landego, Richard J. Lin, Maria Lia Palomba, Allison Parascondola, Jae H. Park, Gilles Salles, Amethyst Saldia, Michael Scordo, Ana Alarcon Tomas, Gunjan L. Shah, Roni Shouval, Ying Taur, Miguel-Angel Perales, Susan K. Seo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3514.
https://doi.org/10.1182/blood-2023-181997
Published: 2023