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David Cordas Dos Santos
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Journal Articles

Single-cell immune profiling reveals enhanced immune fitness of endogenous and engineered T cells in patients with high-risk smoldering myeloma compared to Relapsed/Refractory myeloma following bispecific antibodies or CAR-T cell therapies.

Free
Francesco Corrado, Nayda Bidikian, Anna Bosch-Vilaseca, Yoshinobu Konishi, Rosa Toenges, Jean-Baptiste Alberge, Ting Wu, Sophie Magidson, Lorena Pantano, Michelle Aranha, Elizabeth Lightbody, Joseph Flinn, Michael Timonian, David Cordas Dos Santos, Rocio Montes De Oca, Tamar Lengil, Diego Vieyra, Mark Wildgust, Vicki Plaks, Denise De Wiest, Kevin De Braganca, Shonali Midha, Elizabeth O'Donnell, Yuxin Liu, Ashlee Sturtevant, Kenneth Anderson, Nikhil Munshi, Jerome Ritz, Omar Nadeem, Gad Getz, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 921.
https://doi.org/10.1182/blood-2025-921
Published: 2025
Journal Articles

Results of the promise study from ~30,000 individuals screened for monoclonal gammopathies

Free
Sabine Allam, Sungjae Kim, Jean-Baptiste Alberge, Habib El-Khoury, Floris Chabrun, Jacqueline Perry, Katherine Padgett, Julia Colchie, Joseph Flinn, Grace Fleming, Rachel Choi, Kaitlin Bondi, Ciara Murphy, Sofia Wallin, Luca Bertamini, David Lee, Derek Troske, Dhananjay Sakrikar, David Barnidge, Stephen Harding, David Cordas Dos Santos, Romanos Sklavenitis-Pistofidis, Meletios Dimopoulos, Efstathios Kastritis, Irit Avivi, Wenlong Chen, Maureen Joffe, Elizabeth Karlson, Elizabeth O'Donnell, Omar Nadeem, Lorenzo Trippa, Catherine Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 403.
https://doi.org/10.1182/blood-2025-403
Published: 2025
Journal Articles

Hematotoxicity and immune deficits with bispecific antibodies: A systematic review and meta-analysis in lymphoma and multiple myeloma

Free
Tobias Tix, Mohammad Alhomoud, Jaromir Tomasik, Gloria Iacoboni, Edward Cliff, Doris Hansen, Saad Usmani, Gilles Salles, Marion Subklewe, Michael Von Bergwelt, Samuel Yamshon, Miguel-Angel Perales, Roni Shouval, David Cordas Dos Santos, Kai Rejeski
Journal: Blood
Blood (2025) 146 (Supplement 1): 8135.
https://doi.org/10.1182/blood-2025-8135
Published: 2025
Journal Articles

Identification of persister cells and evolution of tumor clones during immunotherapy and at minimal residual disease timepoints decoded by single-cell whole-genome sequencing in multiple myeloma

Free
Rosa Toenges, Jean-Baptiste Alberge, Tomoki Iemura, Francesco Corrado, Nayda Bidikian, David Cordas Dos Santos, Ankit Dutta, Romanos Sklavenitis-Pistofidis, Subear Hussein, Carlson Ketcham, Sophie Magidson, Shonali Midha, Elizabeth O'Donnell, Adam Sperling, Jacob Laubach, Kenneth Anderson, Eric Smith, Nikhil Munshi, Omar Nadeem, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3930.
https://doi.org/10.1182/blood-2025-3930
Published: 2025
Journal Articles

Spatial proteomics of the bone marrow reveals distinct Tumor–Immune niches in smoldering and relapsed myeloma and their remodeling in response to bispecific antibody and CAR-T therapy

Free
David Cordas Dos Santos, Kane Foster, Daniel Heilpern-Mallory, Sophia Schroeder, Yoshinobu Konishi, Maria-Theresa Silverio, Jacqueline Perry, Sophie Magidson, Diego Vieyra, Rocio Montes De Oca, Daniel Zangrando, Nina Lane, Adam Sperling, Eric Smith, Jacob Laubach, Elizabeth O'Donnell, Nikhil Munshi, Kenneth Anderson, Shonali Midha, Gad Getz, Omar Nadeem, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2025-3921
Published: 2025
Journal Articles

Spatial profiling of the bone marrow microenvironment in patients with IgM gammopathies reveals a T cell–Enriched tumor niche associated with asymptomatic waldenstrom macroglobulinemia progression

Free
David Cordas Dos Santos, Kane Foster, Daniel Heilpern-Mallory, Sophia Schroeder, Minhua Su, Vidhi Patel, Catherine Tobia, Mohammed Rahman, Jacqueline Perry, Daniel Zangrando, Nina Lane, Yoshinobu Konishi, Steven Treon, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3559.
https://doi.org/10.1182/blood-2025-3559
Published: 2025
Journal Articles

Adipose tissue-associated lipid serum signatures modulate efficacy and toxicity of CAR-T cell therapy in lymphoid malignancies

Free
David Cordas Dos Santos, Hannah Thurisch, Jingke Tu, Daniel Heilpern-Mallory, Amar Hadzic, Martin Kirmaier, Werner Schmitz, Martin Vaeth, Sabine Oganesian, Adriano Carboniero, Ludovica Vona, Viktoria Blumenberg, Veit Buecklein, Michael Von Bergwelt, Kai Rejeski, Marion Subklewe, Sebastian Theurich
Journal: Blood
Blood (2025) 146 (Supplement 1): 5887.
https://doi.org/10.1182/blood-2025-5887
Published: 2025