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Journal Articles

Modal CAR T cells: A synthetic cytokine circuit to overcome TGFβ-mediated immunosuppression in AML

Fuguo Liu, Xingyu Deng, Veronica Hui, Maily Nguyen, Wenxin Xu, Mubin Tarannum, Andreia Maia, Shaobo Yang, Remy Dulery, Stephanie Sendker, Alaa Ali, John Koreth, Jose Cancelas, Jianzhu Chen, Robert Soiffer, Catherine Wu, Jerome Ritz, Toni Choueiri, Rizwan Romee

Blood (2025) 146 (Supplement 1): 4096.

https://doi.org/10.1182/blood-2025-4096

Published: 2025

Journal Articles

Early TCR diversity and recipient stem-cell persistence predict relapse and reveal therapeutic targets after allogeneic transplantation

Blood (2025) 146 (Supplement 1): 6065.

https://doi.org/10.1182/blood-2025-6065

Published: 2025

Journal Articles

Single-cell immune profiling reveals enhanced immune fitness of endogenous and engineered T cells in patients with high-risk smoldering myeloma compared to Relapsed/Refractory myeloma following bispecific antibodies or CAR-T cell therapies.

Blood (2025) 146 (Supplement 1): 921.

https://doi.org/10.1182/blood-2025-921

Published: 2025

Journal Articles

Development of a novel multiomic sequencing approach to characterize infused donor memory-like NK cells in an immune compatible environment

Roman Shapiro, Grace Birch, Chen Weng, Jonas Gudera, Michael Poeschla, Matthew Booker, Michael Tolstorukov, Michal Sheffer, Remy Dulery, Sarah Nikiforow, John Koreth, Catherine Wu, Robert Soiffer, Jerome Ritz, Vijay Sankaran, Rizwan Romee

Blood (2025) 146 (Supplement 1): 2352.

https://doi.org/10.1182/blood-2025-2352

Published: 2025

Journal Articles

Long-term follow-up of the first in human post-transcriptional genetic silencing of BCL11A in sickle cell disease in a phase 1 pilot and feasibility trial

Blood (2025) 146 (Supplement 1): 2533.

https://doi.org/10.1182/blood-2025-2533

Published: 2025

Journal Articles

Functional fitness of CAR-T cells in the bone marrow following anti-BCMA durcabtagene autoleucel (PHE885) therapy correlate with prolonged PFS in RRMM

Rao Prabhala, Lakshmi Bhavani Potluri, Srikanth Talluri, Hannah Seah, Vaishnavi Bade, Sahan Vangala, Mehmet Samur, Sarah Nikiforow, Alejandro Alonso, Shuntaro Ikegawa, Sinead Dolan, David Pearson, Pedro Milanez-Almeida, Jennifer Mataraza, Jerome Ritz, Dexiu BU, Marc Credi, Adam Sperling, Nikhil Munshi

Blood (2025) 146 (Supplement 1): 5713.

https://doi.org/10.1182/blood-2025-5713

Published: 2025

Journal Articles

Impact of graft versus host disease prophylaxis with post transplant cyclophosphamide on the prognostic value of HCT-CI

Ansh Mehta, Haesook Kim, Arcita Pramudita, Deborah Liney, Remy Dulery, Vincent Ho, Corey Cutler, John Koreth, Mahasweta Gooptu, Joseph Antin, Amar Kelkar, Sarah Nikiforow, Prashant Nageshwar, Catherine Wu, Jerome Ritz, Rizwan Romee, Robert Soiffer, Roman Shapiro

Blood (2025) 146 (Supplement 1): 4227.

https://doi.org/10.1182/blood-2025-4227

Published: 2025

Journal Articles

HLA mismatch-derived epitopes predict acute graft-versus-host disease risk after unrelated donor transplantation

Nicoletta Cieri, Yiren Shao, Luis Correa-Medero, Julia Keating, Meilun He, Yung-Tsi Bolon, Griffin Lawrence, Jerome Ritz, Robert Soiffer, Jenn Abelin, Donna Neuberg, Stephen Spellman, Catherine Wu

Blood (2025) 146 (Supplement 1): 4249.

https://doi.org/10.1182/blood-2025-4249

Published: 2025

Journal Articles

First-in-human phase 1 trial of trimeric APRIL (TriPRIL) CAR T cells in relapsed or refractory multiple myeloma: Clinical outcomes and biological correlates of disease response and resistance

Blood (2025) 146 (Supplement 1): 270.

https://doi.org/10.1182/blood-2025-270

Published: 2025

Journal Articles

LIME: A first-in-class of live bacterial immune engagers for cancer immunotherapy

Blood (2025) 146 (Supplement 1): 264.

https://doi.org/10.1182/blood-2025-264

Published: 2025

Journal Articles

Reprogramming CAR-NK cells with IL-7/IL-7Rα to amplify STAT1 signaling and activate bystander T cells for enhanced immunotherapy

Blood (2025) 146 (Supplement 1): 4129.

https://doi.org/10.1182/blood-2025-4129

Published: 2025

Journal Articles

Highly efficient collection and manufacture of autologous HSC gene therapy cell product for patients with sickle cell disease using a lentiviral vector containing a shmir targeting BCL11a

Blood (2025) 146 (Supplement 1): 6094.

https://doi.org/10.1182/blood-2025-6094

Published: 2025

Journal Articles

Overcoming CAR T cell resistance in NPM1c and KMT2Ar AML through menin pathway inhibition

Sara Piccinelli, Wallace Bourgeois, Andreia Maia, Eden Bobilev, Fuguo Liu, Xingyu Deng, Han Dong, Robert Soiffer, Catherine Wu, Jerome Ritz, Daniel Deangelo, Andrew Lane, Roman Shapiro, Jianzhu Chen, John Koreth, Rizwan Romee

Blood (2025) 146 (Supplement 1): 2319.

https://doi.org/10.1182/blood-2025-2319

Published: 2025

Journal Articles

Effect of graft cellular content on outcomes in HLA mismatched hematopoietic cell transplantation using post-transplant cyclophosphamide

Remy Dulery, Sandra Lee, Sarah Nikiforow, Carol Reynolds, Heather Garrity, Karl Stasko, Andrew Mason, Corey Cutler, John Koreth, Mahasweta Gooptu, Joseph Antin, Amar Kelkar, Vincent Ho, Catherine Wu, Rizwan Romee, Jerome Ritz, Robert Soiffer, Roman Shapiro

Blood (2025) 146 (Supplement 1): 4260.

https://doi.org/10.1182/blood-2025-4260

Published: 2025

Journal Articles

Mechanisms of immune escape and altered tissue homing in leukemia cutis

Livius Penter, Alexandria Maurer, Nicoletta Cieri, Wesley Lu, Haoxiang Lyu, Shuqiang Li, Kenneth Livak, Lars Bullinger, Jerome Ritz, Pavan Bachireddy, Matthew S Davids, Jacqueline Garcia, Robert Soiffer, Catherine Wu

Blood (2025) 146 (Supplement 1): 2483.

https://doi.org/10.1182/blood-2025-2483

Published: 2025

Journal Articles

Dual-function engineered bacteria remodel AML tumor microenvironment via IL-12 delivery and adenosine depletion to sustain NK cell immunity

Blood (2025) 146 (Supplement 1): 5912.

https://doi.org/10.1182/blood-2025-5912

Published: 2025

Journal Articles

Ven+FluBu2 with ptcy/tac/MMF RIC transplant followed by venetoclax/azacitidine maintenance for high-risk MDS/AML

H. Moses Murdock, Kyle Hebert, Jennifer Brock, Elise Auriemma, Felicia Lim, Jeremy Ryan, Mahasweta Gooptu, Roman Shapiro, Corey Cutler, Amar Kelkar, Vincent Ho, Denbaa Bat-Erdene, Anthony Letai, Jerome Ritz, R. Coleman Lindsley, Joseph Antin, Robert Soiffer, Jacqueline Garcia

Blood (2025) 146 (Supplement 1): 4206.

https://doi.org/10.1182/blood-2025-4206

Published: 2025

Journal Articles

Mechanisms of immune escape and extramedullary tropism in leukemia cutis

Livius Penter, Katie Maurer, Nicoletta Cieri, Wesley Lu, Haoxiang Lyu, Mischa Selig, Maria Joosten, Jana Ihlow, Shuqiang Li, Kenneth J Livak, Lars Bullinger, Jerome Ritz, Pavan Bachireddy, Matthew S. Davids, Jacqueline S. Garcia, Robert J. Soiffer, Catherine J Wu

Blood blood.2025029121.

https://doi.org/10.1182/blood.2025029121

Published: 2025

Includes: Supplemental data

Journal Articles

Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma

Blood (2024) 144 (24): 2490–2502.

https://doi.org/10.1182/blood.2024024381

Published: 2024

Includes: Supplemental data

Journal Articles

Impact of Consolidative Cellular Therapy with DLI or Second Transplant in Patients with AML Who Achieve Complete Remission Following Post-Transplant Relapse

H. Moses Murdock, Haesook T. Kim, Katie Maurer, Amar H. Kelkar, Roman M. Shapiro, Mahasweta Gooptu, Rizwan Romee, Corey S. Cutler, John Koreth, Jerome Ritz, Joseph H. Antin, Vincent T. Ho, Sarah Nikiforow, Catherine J. Wu, Robert J. Soiffer

Blood (2024) 144 (Supplement 1): 3538.

https://doi.org/10.1182/blood-2024-204343

Published: 2024

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Modal CAR T cells: A synthetic cytokine circuit to overcome TGFβ-mediated immunosuppression in AML

Early TCR diversity and recipient stem-cell persistence predict relapse and reveal therapeutic targets after allogeneic transplantation

Single-cell immune profiling reveals enhanced immune fitness of endogenous and engineered T cells in patients with high-risk smoldering myeloma compared to Relapsed/Refractory myeloma following bispecific antibodies or CAR-T cell therapies.

Development of a novel multiomic sequencing approach to characterize infused donor memory-like NK cells in an immune compatible environment

Long-term follow-up of the first in human post-transcriptional genetic silencing of BCL11A in sickle cell disease in a phase 1 pilot and feasibility trial

Functional fitness of CAR-T cells in the bone marrow following anti-BCMA durcabtagene autoleucel (PHE885) therapy correlate with prolonged PFS in RRMM

Impact of graft versus host disease prophylaxis with post transplant cyclophosphamide on the prognostic value of HCT-CI

HLA mismatch-derived epitopes predict acute graft-versus-host disease risk after unrelated donor transplantation

First-in-human phase 1 trial of trimeric APRIL (TriPRIL) CAR T cells in relapsed or refractory multiple myeloma: Clinical outcomes and biological correlates of disease response and resistance

LIME: A first-in-class of live bacterial immune engagers for cancer immunotherapy

Reprogramming CAR-NK cells with IL-7/IL-7Rα to amplify STAT1 signaling and activate bystander T cells for enhanced immunotherapy

Highly efficient collection and manufacture of autologous HSC gene therapy cell product for patients with sickle cell disease using a lentiviral vector containing a shmir targeting BCL11a

Overcoming CAR T cell resistance in NPM1c and KMT2Ar AML through menin pathway inhibition

Effect of graft cellular content on outcomes in HLA mismatched hematopoietic cell transplantation using post-transplant cyclophosphamide

Mechanisms of immune escape and altered tissue homing in leukemia cutis

Dual-function engineered bacteria remodel AML tumor microenvironment via IL-12 delivery and adenosine depletion to sustain NK cell immunity

Ven+FluBu2 with ptcy/tac/MMF RIC transplant followed by venetoclax/azacitidine maintenance for high-risk MDS/AML

Mechanisms of immune escape and extramedullary tropism in leukemia cutis

Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma

Impact of Consolidative Cellular Therapy with DLI or Second Transplant in Patients with AML Who Achieve Complete Remission Following Post-Transplant Relapse

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American Society of Hematology

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