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Jerome Ritz
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Journal Articles

Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma

Clinical Trials & Observations
Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H. Gohil, Shogo Miura, Robert Redd, Haoxiang Lyu, Wesley Lu, Yohei Arihara, Justin Budka, Mikaela McDonough, Michela Ansuinelli, Carol Reynolds, Heather Jacene, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Brodie Miles, Mike Mattie, Donna S. Neuberg, Rafael A. Irizarry, Philippe Armand, Catherine J. Wu, Caron Jacobson
Journal: Blood
Blood (2024) 144 (24): 2490–2502.
https://doi.org/10.1182/blood.2024024381
Published: 2024
Includes: Supplemental data
Journal Articles

Feasibility, Safety and Efficacy of Oral Maintenance Therapy with Venetoclax Plus Decitabine/Cedazuridine after Venetoclax Plus FluBu2 for High Risk MDS/AML Undergoing RIC Allo-HCT

Jacqueline S. Garcia, Haesook T. Kim, Jennifer Brock, H. Moses Murdock, Mahasweta Gooptu, Vincent T. Ho, Roman M. Shapiro, Christopher J. Gibson, Amar H. Kelkar, Corey S. Cutler, Denbaa Bat-Erdene, Jeremy Ryan, Anna Bosch-Vilaseca, Anthony G. Letai, Jerome Ritz, Coleman Lindsley, Robert J. Soiffer, Joseph Antin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1045.
https://doi.org/10.1182/blood-2024-194170
Published: 2024
Journal Articles

Effects of GvHD Prophylaxis with Post-Transplant Cyclophosphamide on Immune Reconstitution and TCR Repertoire after Haploidentical and HLA-Matched Transplantation Compared to Prophylaxis with Calcineurin Inhibitor Plus Methotrexate in HLA-Matched Transplantation

Michela Ansuinelli, Haesook T. Kim, Carol G. Reynolds, Francesco Malfona, Shuntaro Ikegawa, Rakuyo Tamada, Roman M. Shapiro, Mahasweta Gooptu, Rizwan Romee, Sarah Nikiforow, John Koreth, Vincent T. Ho, Corey S. Cutler, Joseph H. Antin, Leslie Kean, Robert J. Soiffer, Jerome Ritz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1041.
https://doi.org/10.1182/blood-2024-201835
Published: 2024
Journal Articles

Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-Charge™ Platform

Shuntaro Ikegawa, Adam S. Sperling, Sarah Nikiforow, Andrew Ghazi, Anthony Christidis, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Allison Charles, Marc Credi, Nina Orwitz, Madisyn Strange, Rakuyo Tamada, Kevin M. Panaro, Casey Gervais, Michela Ansuinelli, Yohei Arihara, Rao Prabhala, Carol G. Reynolds, Robert Gentleman, Serena De Vita, Nikhil C. Munshi, Jerome Ritz
Journal: Blood
Blood (2024) 144 (Supplement 1): 149.
https://doi.org/10.1182/blood-2024-199890
Published: 2024
Journal Articles

Deconvolving Immunologic Networks of the AML Marrow Microenvironment with Spatial Multi-Omic Profiling

Katie Maurer, Florian Raths, Kenneth Gouin, Cameron Y Park, Michael Lawson, Jake Koh, Martin Fabani, Kenneth J. Livak, Jerome Ritz, Robert J. Soiffer, Eli Glezer, Catherine J. Wu, Elham Azizi
Journal: Blood
Blood (2024) 144 (Supplement 1): 928.
https://doi.org/10.1182/blood-2024-204226
Published: 2024
Journal Articles

Early Safety and Efficacy of CAR-T Cell Therapy in Precursor Myeloma: Results of the CAR-PRISM Study Using Ciltacabtagene Autoleucel in High-Risk Smoldering Myeloma

Omar Nadeem, Sarah Nikiforow, Kevin DeBraganca, Anna Bosch-Vilaseca, Elizabeth K. O'Donnell, Adam S. Sperling, Yuxin Liu, Frances Arters, Marjorie Marto, Colin O'Donnell, Brendan Kineavy, Sarah Holmes, Hope Wei, Emily Durlacher, Elizabeth Grimm, Amy Goguen, Rocio Montes de Oca, Lorenzo Trippa, Eric L. Smith, Kenneth C. Anderson, Nikhil C. Munshi, Mark Wildgust, Jerome Ritz, Craig Tendler, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1027.
https://doi.org/10.1182/blood-2024-202676
Published: 2024
Journal Articles

Heterogeneity of PD-1 + regulatory T Cells after Low-Dose IL-2 Therapy for Patients with Chronic Graft-Versus-Host Disease

Shuntaro Ikegawa, Takeru Asano, Bohoon Shim, Mehdi Borji, Haesook T. Kim, Shuqiang Li, Kenneth J. Livak, Gordon J. Freeman, Xia Bu, Roger Belizaire, Jennifer Whangbo, Roman M. Shapiro, Mahasweta Gooptu, Rizwan Romee, Sarah Nikiforow, Vincent T. Ho, Corey S. Cutler, Joseph H. Antin, Robert J. Soiffer, John Koreth, Jeremy M. Simon, Catherine J. Wu, Jerome Ritz
Journal: Blood
Blood (2024) 144 (Supplement 1): 379.
https://doi.org/10.1182/blood-2024-200128
Published: 2024
Journal Articles

Acute GvHD of the Gut Is Associated with Minor Histocompatibility Antigens Cross-Reactive Against Gut-Tropic Viral Epitopes

Nicoletta Cieri, Yiren Shao, Kaila Power, Vincent T. Ho, Jonathan Stevens, William J. Lane, Haesook T. Kim, Donna S. Neuberg, Chip Stewart, Gad Getz, Jerome Ritz, Robert J. Soiffer, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 102.
https://doi.org/10.1182/blood-2024-198976
Published: 2024
Journal Articles

Induction of Graft-Versus-Leukemia Effect with Treg-Depleted DLI Plus Ipilimumab for Myeloid Disease Relapse after HLA-Matched Transplant

Roman M. Shapiro, Haesook T. Kim, William H Terral, Vincent T. Ho, Mahasweta Gooptu, Rizwan Romee, Christopher J. Gibson, Amar H. Kelkar, Corey S. Cutler, Joseph H. Antin, Katie Maurer, Catherine J. Wu, Robert Zeiser, Jerome Ritz, Robert J. Soiffer, Sarah Nikiforow, John Koreth
Journal: Blood
Blood (2024) 144 (Supplement 1): 4833.
https://doi.org/10.1182/blood-2024-194102
Published: 2024
Journal Articles

Early CMV Viral Load Burden Predicts Late Clinically Significant CMV Infections in Patients Receiving Ptcy-Based Hematopoietic Cell Transplantation

Jessica S. Little, Kyle Hebert, Donna S. Neuberg, Sarah Nikiforow, Mahasweta Gooptu, Roman M. Shapiro, John Koreth, Joseph H. Antin, Corey S. Cutler, Robert J. Soiffer, Jerome Ritz, Rizwan Romee, Vincent T. Ho, Nicolas C Issa, Lindsey R. Baden, Remy Dulery, Susan E Prockop
Journal: Blood
Blood (2024) 144 (Supplement 1): 4885.
https://doi.org/10.1182/blood-2024-205169
Published: 2024
Journal Articles

Expression of HLA-B*35 Is Associated with an Increased Risk of CMV Viremia and Clinically Significant CMV Infection in Patients Receiving Ptcy-Based Hematopoietic Cell Transplantation

Jessica S. Little, Kyle Hebert, Donna S. Neuberg, Sarah Nikiforow, Mahasweta Gooptu, Roman M. Shapiro, John Koreth, Joseph H. Antin, Corey S. Cutler, Robert J. Soiffer, Jerome Ritz, Rizwan Romee, Vincent T. Ho, Nicolas C Issa, Lindsey R. Baden, Remy Dulery, Susan E Prockop
Journal: Blood
Blood (2024) 144 (Supplement 1): 4866.
https://doi.org/10.1182/blood-2024-205070
Published: 2024
Journal Articles

BK Virus Reactivation and Disease after Allogeneic Hematopoietic-Cell Transplantation: A Natural History Study

Isabel H. Gonzalez-Bocco, Haesook T. Kim, Kaiwen Chen, Esther Arbona-Haddad, Muneerah Aleissa, Kaitlyn M. Timblin, Jose Orejas, Carol B Benson, Edmund Cibas, Sarah P. Hammond, Nicolas C Issa, Jessica S. Little, Corey S. Cutler, Vincent T. Ho, John Koreth, Mahasweta Gooptu, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, C. Sabrina Tan, Sophia Koo, Francisco M. Marty, Lindsey R. Baden, Jerome Ritz, Matthew P. Cheng
Journal: Blood
Blood (2024) 144 (Supplement 1): 3500.
https://doi.org/10.1182/blood-2024-199776
Published: 2024
Journal Articles

Leukemia Evolution and Resistance to Graft-Versus-Leukemia Responses Revealed By Mitochondrial DNA Mutations

Livius Penter, Nicoletta Cieri, Katie Maurer, Marwan Kwok, Haoxiang Lyu, Wesley S Lu, Giacomo Oliveira, Satyen H Gohil, Ignaty Leshchiner, Caleb Lareau, Leif S Ludwig, Donna S. Neuberg, Haesook T. Kim, Shuqiang Li, Lars Bullinger, Jerome Ritz, Gad Getz, Jacqueline S. Garcia, Robert J. Soiffer, Kenneth J. Livak, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 926.
https://doi.org/10.1182/blood-2024-199009
Published: 2024
Journal Articles

Mesothelin Targeting IL12-Engineered CAR Memory-like NK Cells Demonstrate Promising Efficacy in Acute Myeloid Leukemia

Jieun Jang, Mila Stanojevic, Sara Piccinelli, Michal Sheffer, Grace Caroline Birch, Roman M. Shapiro, Maximilian Stahl, John Koreth, Catherine J. Wu, Robert J. Soiffer, Jerome Ritz, Mubin Tarannum, Rizwan Romee
Journal: Blood
Blood (2024) 144 (Supplement 1): 917.
https://doi.org/10.1182/blood-2024-204369
Published: 2024
Journal Articles

Impact of Consolidative Cellular Therapy with DLI or Second Transplant in Patients with AML Who Achieve Complete Remission Following Post-Transplant Relapse

H. Moses Murdock, Haesook T. Kim, Katie Maurer, Amar H. Kelkar, Roman M. Shapiro, Mahasweta Gooptu, Rizwan Romee, Corey S. Cutler, John Koreth, Jerome Ritz, Joseph H. Antin, Vincent T. Ho, Sarah Nikiforow, Catherine J. Wu, Robert J. Soiffer
Journal: Blood
Blood (2024) 144 (Supplement 1): 3538.
https://doi.org/10.1182/blood-2024-204343
Published: 2024
Journal Articles

One-Step Construction of Allogeneic CAR-NK Cells Preventing Rejection and Mediating Enhanced Anti-Tumor Responses

Fuguo Liu, Mubin Tarannum, Yingjie Zhao, Yiming J Zhang, James Dongjoo Ham, Kewen Lei, Yuhao Qiang, Xingyu Deng, Maily Nguyen, Dinh Khanhlinh, Shaobo Yang, Alaa Kassim Ali, Grace Caroline Birch, Yuwen Yin, Junru Cui, Fangfeng Yuan, Jerome Ritz, Jianzhu Chen, Rizwan Romee
Journal: Blood
Blood (2024) 144 (Supplement 1): 915.
https://doi.org/10.1182/blood-2024-198167
Published: 2024
Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ + T cells targeting multiple myeloma

Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Derin B. Keskin, Kenneth Livak, Shuqiang Li, Mubin Tarannum, Rizwan Romee, Mehmet Samur, Nikhil C. Munshi, Shin Kaneko, Jerome Ritz, Kenneth C. Anderson
Journal: Blood
Blood (2024) 143 (10): 895–911.
https://doi.org/10.1182/blood.2023020528
Published: 2024
Includes: Supplemental data
Journal Articles

ASXL1 Truncating Mutations Drive Leukemic Resistance to T Cell Attack

Dustin McCurry, Zhongqi Ge, Jaehyun Lee, Pranaya Raparla, Thomas Koehnke, Rishi Pasumarthi, Xiaohong Leng, Oren Pasvolsky, Vinhkhang Nguyen, Katie Maurer, Shuqiang Li, Kenneth J. Livak, Elham Azizi, Robert J. Soiffer, Sachet Shukla, Ravindra Majeti, Jerome Ritz, Catherine J Wu, Jeffrey J. Molldrem, Pavan Bachireddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 364.
https://doi.org/10.1182/blood-2023-189177
Published: 2023
Journal Articles

An Analytic Framework for the Prediction of Gvl Minor Histocompatibility Antigens to Prevent or Treat Post-Transplant Relapse

Nicoletta Cieri, Liang Li, Nidhi Hookeri, Kari Stromhaug, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 361.
https://doi.org/10.1182/blood-2023-187705
Published: 2023