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Journal Articles

Discerning the Landscape of Menin Inhibitor Resistance

Wallace Bourgeois, Jevon Cutler, Hannah E Rice, Brandon Regalado, Daniela V. Wenge, Florian Perner, John G. Doench, Jerry M McGeehan, Scott A Armstrong
Journal: Blood
Blood (2024) 144 (Supplement 1): 724.
https://doi.org/10.1182/blood-2024-208887
Published: 2024
Journal Articles

Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A -r and NPM1c AML

Wallace Bourgeois, Jevon A. Cutler, Brandon J. Aubrey, Daniela V. Wenge, Florian Perner, Cynthia Martucci, Jill A. Henrich, Kelly Klega, Radosław P. Nowak, Katherine A. Donovan, Meaghan Boileau, Yanhe Wen, Charlie Hatton, Athina A. Apazidis, Sarah Naomi Olsen, Nadia Kirmani, Yana Pikman, Jessica A. Pollard, Jennifer A. Perry, Adam S. Sperling, Benjamin L. Ebert, Gerard M. McGeehan, Brian D. Crompton, Eric S. Fischer, Scott A. Armstrong
Journal: Blood
Blood (2024) 143 (15): 1513–1527.
https://doi.org/10.1182/blood.2023021105
Published: 2024
Includes: Supplemental data
Journal Articles

Menin Inhibitor Induced Menin Protein Degradation Contributes to Menin Inhibitor Efficacy

Jevon Cutler, Jonathan Tsai, Brandon Regalado, Wallace Bourgeois, Daniela Wenge, Jeonghyeon Kim, Radoslaw Nowak, Elizabeth Ener, Katherine Donovan, Sarah Naomi Olsen, Eric Fischer, Benjamin L. Ebert, Scott A Armstrong
Journal: Blood
Blood (2023) 142 (Supplement 1): 2788.
https://doi.org/10.1182/blood-2023-184931
Published: 2023
Journal Articles

Potent Ikaros Degradation By the Cereblon E3 Ligase Modulator CC-92480 Is Effective in Combination with Menin-MLL1 Inhibition in MLL1 -Rearranged and NPM1 -Mutant AML

Wallace Bourgeois, Brandon J. Aubrey, Jevon A. Cutler, Katherine A. Donovan, Charles Hatton, Alexandra C. P. Theall, Radoslaw P. Nowak, Gerard M. McGeehan, Eric S. Fischer, Scott A. Armstrong
Journal: Blood
Blood (2021) 138 (Supplement 1): 208.
https://doi.org/10.1182/blood-2021-150971
Published: 2021
Journal Articles

Health Care Utilization and Cost of Allogeneic Hematopoietic Cell Transplantation in Children with Malignant and Non-Malignant Diseases

Angela Ricci, MD, Zhezhen Jin, PhD, Wallace Bourgeois, MD, Matt Hall, PhD, Prakash Satwani, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2109.
https://doi.org/10.1182/blood.V130.Suppl_1.2109.2109
Published: 2017
Journal Articles

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia

Courtney L. Jones, Christy M. Gearheart, Susan Fosmire, Cristina Delgado-Martin, Nikki A. Evensen, Karen Bride, Angela J. Waanders, Faye Pais, Jinhua Wang, Teena Bhatla, Danielle S. Bitterman, Simone R. de Rijk, Wallace Bourgeois, Smita Dandekar, Eugene Park, Tamara M. Burleson, Pillai Pallavi Madhusoodhan, David T. Teachey, Elizabeth A. Raetz, Michelle L. Hermiston, Markus Müschen, Mignon L. Loh, Stephen P. Hunger, Jinghui Zhang, Michael J. Garabedian, Christopher C. Porter, William L. Carroll
Journal: Blood
Blood (2015) 126 (19): 2202–2212.
https://doi.org/10.1182/blood-2015-04-639138
Published: 2015
Includes: Supplemental data
Journal Articles

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

Courtney L Jones, PhD, Christy M Gearheart, PhD, Susan Fosmire, Cristina Delgado-Martin, PhD, Faye Pais, MD, Jinhua Wang, PhD, Teena Bhatla, MD, Danielle S Bitterman, Simone R de Rijk, Wallace Bourgeois, Smita C. Dandekar, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD PhD, Michael J Garabedian, PhD, Christopher C. Porter, MD, William L. Carroll, MD
Journal: Blood
Blood (2014) 124 (21): 789.
https://doi.org/10.1182/blood.V124.21.789.789
Published: 2014
Journal Articles

Inhibition Of The Wnt Pathway Leads To Improved Chemosensitivity In Pediatric Acute Lymphoblastic Leukemia

Smita C. Dandekar, MD, Eleny Romanos-Sirakis, MD, Faye Pais, Ph.D., Teena Bhatla, MD, Courtney L Jones, Wallace Bourgeois, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD, PhD, Ramanuj Dasgupta, Debra J. Morrison, PhD, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 1428.
https://doi.org/10.1182/blood.V122.21.1428.1428
Published: 2013
Journal Articles

Genome-Wide shRNA Screen Implicates Mitogen Activated Protein Kinase (MAPK) Pathway In Glucocorticoid Resistance In Acute Lymphoblastic Leukemia

Jones L. Courtney, Christy M. Gearheart, Ph.D., Fosmire Susan, Wang Jinhua, Ph.D., Danielle S. Bitterman, Teena Bhatla, MD, Wallace Bourgeois, Christopher C. Porter, MD, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 1296.
https://doi.org/10.1182/blood.V122.21.1296.1296
Published: 2013
Journal Articles

Deletions In TBL1XR1 Results In Glucocorticoid Resistance By Decreasing Glucocorticoid Signaling In Childhood B-Lymphoblastic Leukemia

Courtney L Jones, Teena Bhatla, MD, Jinhua Wang, PhD, Wallace Bourgeois, Bitterman S Danielle, Elizabeth A. Raetz, MD, Debra J. Morrison, PhD, David T. Teachey, MD, Garabedian Michael, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 602.
https://doi.org/10.1182/blood.V122.21.602.602
Published: 2013