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Journal Articles

Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study

Clinical Trials & Observations
Teena Bhatla, Laura E. Hogan, David T. Teachey, Francisco Bautista, John Moppett, Pablo Velasco Puyó, Concetta Micalizzi, Claudia Rossig, Neerav Shukla, Gil Gilad, Franco Locatelli, André Baruchel, C. Michel Zwaan, Natalie S. Bezler, Alba Rubio-San-Simón, David C. Taussig, Elizabeth A. Raetz, Zhengwei J. Mao, Brent L. Wood, Diana Alvarez Arias, Maria Krevvata, Ivo Nnane, Nibedita Bandyopadhyay, Lorena Lopez Solano, Robyn M. Dennis, Robin Carson, Ajay Vora
Journal: Blood
Blood (2024) 144 (21): 2237–2247.
https://doi.org/10.1182/blood.2024024493
Published: 2024
Includes: Supplemental data
Journal Articles

Knowledge and Perceptions about Curative Therapies for Sickle Cell Disease and Hydroxyurea Among Caregivers and Patients at a Large Tertiary Care Center: A Survey Study

Amanda Walker, Olivia Faye Scott, Vipluv Singh, Lucie Pham, Teena Bhatla, Surabhi Batra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5305.
https://doi.org/10.1182/blood-2023-190408
Published: 2023
Journal Articles

Anti-Leukemic Activity of Luveltamab Tazevibulin (LT, STRO-002), a Novel Folate Receptor-α (FR-α)-Targeting Antibody Drug Conjugate (ADC) in Relapsed/Refractory CBF2AT3::GLIS2 AML

Robin Williams, Lane Miller, Stephanie Massaro, Elizabeth Krieger, Melinda Pauly, Catherine Nelson, Rebecca Johnson, Jennifer J.G. Welch, Deepa Bhojwani, Babak Moghimi, Philip Neff, Terzah M. Horton, Hamayun Imran, Raul C. Ribeiro, Terri L. Guinipero, Matthew A. Kutny, Felipe Bautista, Amy Johnson, Karen Lewing, Alan S Gamis, Julienne Brackett, David McCall, Teena Bhatla, Maria Luisa Sulis, Amy Tellinghuisen, Jill C. Beck, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4295.
https://doi.org/10.1182/blood-2023-180141
Published: 2023
Journal Articles

Prognostic Importance of Cytogenetic Subgroups in Relapse Risk Stratification in Children and Young Adults with First Relapsed B-ALL: A Children's Oncology Group Study AALL1331

Teena Bhatla, Laura Hogan, Xinxin Xu, Lingyun Ji, Andrew J. Carroll, Nyla A. Heerema, Mary Shago, Lia Gore, James A. Whitlock, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown
Journal: Blood
Blood (2022) 140 (Supplement 1): 3476–3477.
https://doi.org/10.1182/blood-2022-166523
Published: 2022
Journal Articles

A Randomized Phase 3 Trial of Blinatumomab Vs. Chemotherapy As Post-Reinduction Therapy in Low Risk (LR) First Relapse of B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Adolescents/Young Adults (AYAs): A Report from Children's Oncology Group Study AALL1331

Patrick A. Brown, Lingyun Ji, Xinxin Xu, Meenakshi Devidas, Laura Hogan, Teena Bhatla, Michael Borowitz, Elizabeth A. Raetz, Lia Gore, James A. Whitlock, Stephen P. Hunger, Mignon L. Loh
Journal: Blood
Blood (2021) 138 (Supplement 1): 363.
https://doi.org/10.1182/blood-2021-147946
Published: 2021
Journal Articles

Cytogenetic Subgroups Drive Risk Stratification and Response to Chemotherapy and Blinatumomab in Children and Young Adults with Relapsed B-ALL: A Children's Oncology Group Study

Teena Bhatla, MD, Laura Hogan, MD, Xinxin Xu, MS, Lingyun Ji, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Mary Shago, PhD, Lia Gore, MD, James A. Whitlock, MD, Stephen P Hunger, MD, Mignon L. Loh, MD, Patrick A. Brown, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-136364
Published: 2020
Journal Articles

Induction Toxicities Are More Frequent in Young Adults Compared to Children Treated on the Children's Oncology Group (COG) First Relapse B-Lymphoblastic Leukemia Clinical Trial AALL1331

Laura Brook Hogan, MD, Teena Bhatla, MD, Sue Rheingold, MD, Lingyun Ji, PhD, Xinxin Xu, Elizabeth A. Raetz, MD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Patrick Brown, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1382.
https://doi.org/10.1182/blood-2018-99-112269
Published: 2018
Journal Articles

Genomic and Epigenetic Effects of DNA Methyltransferase Inhibition in Acute Lymphoblastic Leukemia

Shella Saint Fleur-Lominy, MDPhD, Teena Bhatla, MD, Stephen Kelly, MS, Varshini Vasudevaraja, MS, Aristotelis Tsirigos, PhD, William L. Carroll, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2479.
https://doi.org/10.1182/blood.V130.Suppl_1.2479.2479
Published: 2017
Journal Articles

Measurement of Phosphorylated ERK As a Prognostic and Predictive Marker for MEK Inhibition in Pediatric B-Lymphoblastic Leukemia: A Pilot Study

Pillai Pallavi Madhusoodhan, MD, Nikki Ann Evensen, PhD BS, Jason Saliba, PhD, Ashfiyah Chowdhury, BS, Daniel Newman, BA, BS, Cristina Delgado-Martin, PhD, Teena Bhatla, MD, Mignon L. Loh, MD, Michelle L. Hermiston, MD PhD, William L. Carroll, MD
Journal: Blood
Blood (2016) 128 (22): 1739.
https://doi.org/10.1182/blood.V128.22.1739.1739
Published: 2016
Journal Articles

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia

Courtney L. Jones, Christy M. Gearheart, Susan Fosmire, Cristina Delgado-Martin, Nikki A. Evensen, Karen Bride, Angela J. Waanders, Faye Pais, Jinhua Wang, Teena Bhatla, Danielle S. Bitterman, Simone R. de Rijk, Wallace Bourgeois, Smita Dandekar, Eugene Park, Tamara M. Burleson, Pillai Pallavi Madhusoodhan, David T. Teachey, Elizabeth A. Raetz, Michelle L. Hermiston, Markus Müschen, Mignon L. Loh, Stephen P. Hunger, Jinghui Zhang, Michael J. Garabedian, Christopher C. Porter, William L. Carroll
Journal: Blood
Blood (2015) 126 (19): 2202–2212.
https://doi.org/10.1182/blood-2015-04-639138
Published: 2015
Includes: Supplemental data
Journal Articles

Deciphering the Epigenetic Landscape of Relapsed Pediatric Acute Lymphoblastic Leukemia

Teena Bhatla, MD, Roy Blum, PhD, Jinhua Wang, PhD, Courtney L Jones, PhD, Debra J. Morrison, PhD, Elizabeth A Raetz, MD, Michael J. Burke, MD, Patrick Brown, MD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Mignon Loh, MD, Stephen P. Hunger, MD, William L. Carroll, MD
Journal: Blood
Blood (2014) 124 (21): 612.
https://doi.org/10.1182/blood.V124.21.612.612
Published: 2014
Journal Articles

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

Courtney L Jones, PhD, Christy M Gearheart, PhD, Susan Fosmire, Cristina Delgado-Martin, PhD, Faye Pais, MD, Jinhua Wang, PhD, Teena Bhatla, MD, Danielle S Bitterman, Simone R de Rijk, Wallace Bourgeois, Smita C. Dandekar, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD PhD, Michael J Garabedian, PhD, Christopher C. Porter, MD, William L. Carroll, MD
Journal: Blood
Blood (2014) 124 (21): 789.
https://doi.org/10.1182/blood.V124.21.789.789
Published: 2014
Journal Articles

Inhibition Of The Wnt Pathway Leads To Improved Chemosensitivity In Pediatric Acute Lymphoblastic Leukemia

Smita C. Dandekar, MD, Eleny Romanos-Sirakis, MD, Faye Pais, Ph.D., Teena Bhatla, MD, Courtney L Jones, Wallace Bourgeois, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD, PhD, Ramanuj Dasgupta, Debra J. Morrison, PhD, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 1428.
https://doi.org/10.1182/blood.V122.21.1428.1428
Published: 2013
Journal Articles

Genome-Wide shRNA Screen Implicates Mitogen Activated Protein Kinase (MAPK) Pathway In Glucocorticoid Resistance In Acute Lymphoblastic Leukemia

Jones L. Courtney, Christy M. Gearheart, Ph.D., Fosmire Susan, Wang Jinhua, Ph.D., Danielle S. Bitterman, Teena Bhatla, MD, Wallace Bourgeois, Christopher C. Porter, MD, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 1296.
https://doi.org/10.1182/blood.V122.21.1296.1296
Published: 2013
Journal Articles

Deletions In TBL1XR1 Results In Glucocorticoid Resistance By Decreasing Glucocorticoid Signaling In Childhood B-Lymphoblastic Leukemia

Courtney L Jones, Teena Bhatla, MD, Jinhua Wang, PhD, Wallace Bourgeois, Bitterman S Danielle, Elizabeth A. Raetz, MD, Debra J. Morrison, PhD, David T. Teachey, MD, Garabedian Michael, William L. Carroll, MD
Journal: Blood
Blood (2013) 122 (21): 602.
https://doi.org/10.1182/blood.V122.21.602.602
Published: 2013
Journal Articles

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia

Teena Bhatla, Jinhua Wang, Debra J. Morrison, Elizabeth A. Raetz, Michael J. Burke, Patrick Brown, William L. Carroll
Journal: Blood
Blood (2012) 119 (22): 5201–5210.
https://doi.org/10.1182/blood-2012-01-401687
Published: 2012
Includes: Supplemental data
Journal Articles

Epigenetic Modulation Leads to Re-Expression of Relapse Specific Silenced Genes and Induces Chemosensitivity in Childhood Acute Lymphoblastic Leukemia (ALL),

Teena Bhatla, MD, Debra J. Morrison, PhD, Jinhua Wang, PhD, Elizabeth A. Raetz, MD, Michael Burke, MD, Patrick Brown, MD, William L. Carroll, MD
Journal: Blood
Blood (2011) 118 (21): 3455.
https://doi.org/10.1182/blood.V118.21.3455.3455
Published: 2011
Journal Articles

Vorinostat Reverses Relapse-Specific Drug Resistance Gene Expression Signatures In Childhood Acute Lymphoblastic Leukemia (ALL).

Teena Bhatla, MD, Jinhua Wang, PhD, Debra J. Morrison, PhD, Wafik T. Zaky, MD, Elizabeth A. Raetz, MD, William L. Carroll, MD
Journal: Blood
Blood (2010) 116 (21): 3630.
https://doi.org/10.1182/blood.V116.21.3630.3630
Published: 2010