1-20 of 24
John Moppett
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study

Clinical Trials & Observations
Teena Bhatla, Laura E. Hogan, David T. Teachey, Francisco Bautista, John Moppett, Pablo Velasco Puyó, Concetta Micalizzi, Claudia Rossig, Neerav Shukla, Gil Gilad, Franco Locatelli, André Baruchel, C. Michel Zwaan, Natalie S. Bezler, Alba Rubio-San-Simón, David C. Taussig, Elizabeth A. Raetz, Zhengwei J. Mao, Brent L. Wood, Diana Alvarez Arias, Maria Krevvata, Ivo Nnane, Nibedita Bandyopadhyay, Lorena Lopez Solano, Robyn M. Dennis, Robin Carson, Ajay Vora
Journal: Blood
Blood (2024) 144 (21): 2237–2247.
https://doi.org/10.1182/blood.2024024493
Published: 2024
Includes: Supplemental data
Journal Articles

Cerebrospinal Fluid Flow Cytometry Improves Patient Stratification in Central Nervous System Acute Lymphoblastic Leukaemia but Requires Careful Standardization: Results from the ALLTogether1 CSF-FLOW Sub-Study

Ilaria Di Fazio, Lena Behrmann, Valerie de Haas, Victoria Dimitrova, Joaquin Duarte, Gabriele Escherich, Arja Harila, Mats Heyman, Mattias Hofmans, Magnus Hultdin, Inga Johannsdottir, Andrea Malone, Hanne Vibeke Marquart, Reda Matuzeviciene, Veerle Mondelaers, John Moppett, Liv T. N. Osnes, Samuli Rounioja, Kjeld Schmiegelow, Mervi Taskinen, Goda Vaitkeviciene, Inge M. van der Sluis, Lucy Wheeler, Christina Halsey
Journal: Blood
Blood (2024) 144 (Supplement 1): 2831.
https://doi.org/10.1182/blood-2024-203138
Published: 2024
Journal Articles

Blinatumomab with De-Escalated Chemotherapy for Infant KMT2A -Rearranged B-Cell Acute Lymphoblastic Leukemia

Angus Hodder, Avijeet Kumar Mishra, Philip Connor, Michelle Cummins, Danny Cheng, Michael Gattens, Brenda Gibson, Danielle Ingham, Katherine Lindsay, Andrea Malone, Majid Madni, John Moppett, Jayashree Motwani, Pritesh Patel, Subramaniam Ramanathan, Anindita Roy, Beki James, Phil Ancliff, Ajay Vora, Jack Bartram
Journal: Blood
Blood (2024) 144 (Supplement 1): 2816.
https://doi.org/10.1182/blood-2024-205461
Published: 2024
Journal Articles

Title: Risk Factors and Natural History of Vincristine Induced Neuropathy on UKALL 2011: A Randomised Controlled Trial of the Effect of Omitting Vincristine Pulses

Lucy Alderson, Lucy Waller, Mario Cortina Borja, Amy A Kirkwood, Vickaynne Carruthers, David Jamieson, Pam Kearns, Amrana Qureshi, Susan Baird, Jayashree Motwani, Rachael Hough, John Moppett, Ajay Vora, Gareth Veal, Sujith Samarasinghe
Journal: Blood
Blood (2023) 142 (Supplement 1): 2831.
https://doi.org/10.1182/blood-2023-181721
Published: 2023
Journal Articles

High Dose Methotrexate Does Not Reduce the Risk of CNS Relapse in Children and Young Adults with Acute Lymphoblastic Leukaemia and Lymphoblastic Lymphoma. Results of the Randomised Phase III Study UKALL 2011

Amy A. Kirkwood, Nicholas Goulden, John Moppett, Sujith Samarasinghe, Jon Mee, Rachael Hough, Pamela R. Kearns, Sarah Lawson, Clare J. Rowntree, Ajay Vora
Journal: Blood
Blood (2022) 140 (Supplement 1): 516–518.
https://doi.org/10.1182/blood-2022-160129
Published: 2022
Journal Articles

Reduced Intensity Reinduction Followed By Blinatumomab Achieves Excellent MRD Clearance with Reduced Toxicity and Facilitates Timely Transplant in Children and Young People with Relapsed B-Precursor Acute Lymphoblastic Leukemia

Angus Hodder, Avijeet K Mishra, Katherine Clesham, Susan Baird, Kaljit Bhuller, Ismail Bisho, Denise Bonney, Anna Castleton, Michelle Cummins, Emmy Dickens, Lindsay George, Sara Ghorashian, Brenda Gibson, Chris Hasley, Nicholas Heaney, Rachael E Hough, Danielle Ingham, Galina Jigoulina, Katherine Lindsay, Donna Lancaster, Majid Madni, Andrea Malone, Bethany Mitchell, Anthony V. Moorman, John Moppett, Vanessa McLelland, Jayashree Motwani, Emma Nicholson, Caroline Osborne, Katharine Patrick, Lamia Samrin, Sanjay Tewari, Indu Rakesh Thakur, Sujith Samarasinghe, Ajay Vora, David O'Connor
Journal: Blood
Blood (2022) 140 (Supplement 1): 3268–3270.
https://doi.org/10.1182/blood-2022-162565
Published: 2022
Journal Articles

Blinatumomab As Toxicity Sparing First Line Treatment of Children and Young Persons with B-Precursor Acute Lymphoblastic Leukaemia (B-ALL)

Angus Hodder, Avijeet K Mishra, Susan Baird, Ismail Bisho, Denise Bonney, Katherine Clesham, Michelle Cummins, Emmy Dickens, Brenda Gibson, Lindsay George, Danielle Ingham, Galina Jigoulina, Donna Lancaster, Katherine Lindsay, Majid Madni, Andrea Malone, Bethany Mitchell, John Moppett, Jayashree Motwani, Anthony V. Moorman, Katharine Patrick, Lamia Samrin, Sanjay Tewari, Indu Rakesh Thakur, David O'Connor, Ajay Vora, Sujith Samarasinghe
Journal: Blood
Blood (2022) 140 (Supplement 1): 8987–8988.
https://doi.org/10.1182/blood-2022-162475
Published: 2022
Journal Articles

Transplantation for Congenital Sideroblastic Anaemia Is Feasible and Offers Outcomes Comparable to Other Transfusion Dependent Anaemias. a Joint Retrospective Study of the Paediatric Diseases and Severe Aplastic Anaemia Working Parties (PDWP/SAAWP) of EBMT

Josu de la Fuente, Dirk-Jan Eikema, Paul Bosman, Robert F Wynn, MRCP,MDFRCPath, Miguel Díaz, Peter J Shaw, MD, Amal Al-Seraihy, MD, Muhlis Cem Ar, MD PhD, Mohamed Salaheldin Mohamed, Dominique Bron, MDPhD, Cristina Díaz de Heredia, MD PhD, Tobias Gedde-Dahl, Brenda Gibson, MD PhD, Rupert Handgretinger, MD, Professor John G. Gribben, MD DSc, Tessa Kerre, MD, Vassiliki Kitra-Roussou, MD, Stig Lenhoff, Jose Maria Moraleda, MD PhD, Antonio Perez Martinez, MD PhD, John Moppett, FRCPath, Henrik Sengeloev, Abdelghani Tbakhi, MD, Hendrik Veelken, MD PhD, Estelle Verburgh, MBChB, M MDInt, FCPSA, PhD, Giuseppe Visani, Antonio Risitano, Carlo Dufour, Selim Corbacioglu, MD, Regis Peffault De Latour, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–47.
https://doi.org/10.1182/blood-2020-142397
Published: 2020
Journal Articles

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Amir Enshaei, David O’Connor, Jack Bartram, Jeremy Hancock, Christine J. Harrison, Rachael Hough, Sujith Samarasinghe, Monique L. den Boer, Judith M. Boer, Hester A. de Groot-Kruseman, Hanne V. Marquart, Ulrika Noren-Nystrom, Kjeld Schmiegelow, Claire Schwab, Martin A. Horstmann, Gabriele Escherich, Mats Heyman, Rob Pieters, Ajay Vora, John Moppett, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (17): 1438–1446.
https://doi.org/10.1182/blood.2019003191
Published: 2020
Includes: Supplemental data
Journal Articles

Preliminary Outcomes of Children and Young Adults with Acute Lymphoblastic Leukaemia and Down Syndrome (DS-ALL) on UKALL 2011. Reduction in Treatment-Related Mortality with De-Escalated Therapy

Sara Ghorashian, FRCPath, PhD, Sujith Samarasinghe, Amy A Kirkwood, MSc, Rachael Hough, MD BMBS, FRCP, FRCPath, Clare Rowntree, MD, Sarah Lawson, MD, Nicholas John Goulden, MD PhD MRCPath, Emma Pond, PhD, Pamela R. Kearns, PhDFRCPC, Anthony V. Moorman, PhD, John Moppett, Ajay Vora, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 656.
https://doi.org/10.1182/blood-2018-99-118426
Published: 2018
Journal Articles

Dexamethasone Pharmacokinetics Following Standard and Short Dosing Schedules in Patients on the UKALL2011 Trial

Rosanna Jackson, BSc, MSc, Philip Berry, BSc, Julie Errington, MSc, John Moppett, MD, Sujith Samarasinghe, Rachael Hough, MD BMBS, FRCP, FRCPath, Clare Rowntree, MD, Nicholas John Goulden, MD PhD MRCPath, Ajay Vora, MD, Pamela R. Kearns, PhDFRCPC, Julie Irving, PhD, Gareth J Veal, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 101.
https://doi.org/10.1182/blood.V130.Suppl_1.101.101
Published: 2017
Journal Articles

UKALL 2011: Randomised Trial Investigating a Short Induction Dexamethasone Schedule for Children and Young Adults with Acute Lymphoblastic Leukaemia

Nicholas John Goulden, MD PhD MRCPath, Amy A Kirkwood, John Moppett, MD, Sujith Samarasinghe, Sarah Lawson, MD, Clare Rowntree, MD, Rachael Hough, MD BMBS, FRCP, FRCPath, Rajbir Athwal, Pamela R. Kearns, PhDFRCPC, Ajay Vora, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 141.
https://doi.org/10.1182/blood.V130.Suppl_1.141.141
Published: 2017
Journal Articles

Immunoglobulin/T-Cell Receptor (Ig/TCR) Allele Usage in Normal and on Treatment Bone Marrow Samples in Childhood Acute Lymphoblastic Leukaemia - Implications for NGS Based MRD Analysis

John Moppett, MD PhD, Stephanie Wakeman, BSc, Marc Duez, Jack Bartram, MD, Gary Wright, Mike Hubank, PhD, Helen Williamson, Paul Archer, Jerry Hancock, PhD
Journal: Blood
Blood (2016) 128 (22): 4073.
https://doi.org/10.1182/blood.V128.22.4073.4073
Published: 2016
Journal Articles

Artificial DNA Templates for the Correction of PCR Bias in Next Generation Sequencing Based MRD Analysis for Childhood Acute Lymphoblastic Leukaemia: The Influence of Secondary DNA Structure

John Moppett, MD PhD, Jerry Hancock, PhD, Marc Duez, Jack Bartram, MD, Gary Wright, Mike Hubank, PhD, Paul Archer, Helen Williamson, Stephanie Wakeman, BSc
Journal: Blood
Blood (2016) 128 (22): 4078.
https://doi.org/10.1182/blood.V128.22.4078.4078
Published: 2016
Journal Articles

Integrating Genetic Risk Factors with Age, Presenting White Cell Count and MRD Response As Continuous Variables to Predict Relapse in Paediatric Acute Lymphoblastic Leukemia (ALL)

Anthony V. Moorman, PhD, Amir Enshaei, PhD, David O'Connor, MD PhD, Jack Bartram, MD, Jeremy Hancock, PhD, Christine Harrison, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2016) 128 (22): 603.
https://doi.org/10.1182/blood.V128.22.603.603
Published: 2016
Journal Articles

EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications

Brief Report
Claire Schwab, Sarra L. Ryan, Lucy Chilton, Alannah Elliott, James Murray, Stacey Richardson, Christopher Wragg, John Moppett, Michelle Cummins, Oliver Tunstall, Catriona A. Parker, Vaskar Saha, Nicholas Goulden, Ajay Vora, Anthony V. Moorman, Christine J. Harrison
Journal: Blood
Blood (2016) 127 (18): 2214–2218.
https://doi.org/10.1182/blood-2015-09-670166
Published: 2016
Includes: Supplemental data
Journal Articles

Library Preparation Is the Major Factor Affecting Differences in Results of Immunoglobulin Gene Rearrangements Detection on Two Major Next-Generation Sequencing Platforms

Michaela Kotrova, MD, Henrik Knecht, Jack Bartram, MD, Vojtech Bystry, Giovanni Cazzaniga, Grazia Fazio, PhD, Simone Ferrero, Elisa Genuardi, Ramon Garcia-Sanz, MD PhD, Andrea Grioni, Jeremy Hancock, PhD, Cristina Jiminez, Marco Ladetto, John Moppett, MD PhD, Simona Songia, Dietrich Herrmann, Christiane Pott, MD PhD, Anton W. Langerak, Nikos Darzentas, Jan Trka, Eva Fronkova, Monika Bruggemann
Journal: Blood
Blood (2015) 126 (23): 1411.
https://doi.org/10.1182/blood.V126.23.1411.1411
Published: 2015
Journal Articles

Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial

David O'Connor, MD PhD, Jack Bartram, MD, Amir Enshaei, PhD, Anthony V Moorman, PhD, Christine Harrison, PhDFRCPath FMedSci, Rachel Wade, MSc, Rachel Clack, MSc, Jeremy Hancock, PhD, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1412.
https://doi.org/10.1182/blood.V126.23.1412.1412
Published: 2015
Journal Articles

Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD:Â Results from a Large Multi-Center Randomized Controlled Trial, UKALL 2003

Jack Bartram, MD, David O'Connor, MD PhD, Amir Enshaei, PhD, Anthony V Moorman, PhD, Christine Harrison, PhDFRCPath FMedSci, Rachel Wade, MSc, Rachel Clack, MSc, Jeremy Hancock, PhD, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2015) 126 (23): 806.
https://doi.org/10.1182/blood.V126.23.806.806
Published: 2015
Journal Articles

EBF1-PDGFRΒ Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications

Claire Schwab, Rebecca Andrews, Lucy Chilton, Alannah Elliott, Gerald Keil, Stacey Richardson, Sarra L. Ryan, Christopher Wragg, John Moppett, Michelle Cummins, MD, Nicholas Goulden, MD PhD, Ajay J. Vora, Anthony V. Moorman, Christine J. Harrison
Journal: Blood
Blood (2014) 124 (21): 1068.
https://doi.org/10.1182/blood.V124.21.1068.1068
Published: 2014