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Journal Articles

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Alastair L Smith, Nicholas Denny, Catherine M Chahrour, Natalina Elliott, Thomas Jackson, Joe Harman, Huimin Geng, Irene Roberts, Nicholas Crump, James Oliver Davies, Anindita Roy, Thomas A Milne

Blood (2024) 144 (Supplement 1): 201.

https://doi.org/10.1182/blood-2024-208035

Published: 2024

Journal Articles

Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan

Tomoya Isobe, Mariana Quiroga Londoño, Nicole Mende, Emily Stephenson, Deena Iskander, Simone Webb, Issac Goh, Vijay Shanmugiah, Rebecca Hannah, Anindita Roy, Irene Roberts, Elisa Laurenti, Muzlifah Haniffa, Nicola K. Wilson, Berthold Gottgens

Blood (2024) 144 (Supplement 1): 2659.

https://doi.org/10.1182/blood-2024-204131

Published: 2024

Journal Articles

The Fetal Specific Gene LIN28B Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Rebecca E Ling, Thomas Jackson, Natalina Elliott, Joe W Cross, Lucy Hamer, Arundhati S Wuppalapati, Alastair L Smith, Catherine M Chahrour, Okan Sevim, Deena Iskander, Guanlin Wang, Sorcha I O'Byrne, Siobhan Rice, Joe R Harman, Bethan Psaila, Rhys G Morgan, Irene Roberts, Thomas A Milne, Anindita Roy

Blood (2024) 144 (Supplement 1): 199.

https://doi.org/10.1182/blood-2024-198819

Published: 2024

Journal Articles

Blinatumomab with De-Escalated Chemotherapy for Infant KMT2A -Rearranged B-Cell Acute Lymphoblastic Leukemia

Blood (2024) 144 (Supplement 1): 2816.

https://doi.org/10.1182/blood-2024-205461

Published: 2024

Journal Articles

A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Blood (2023) 142 (20): 1752–1756.

https://doi.org/10.1182/blood.2023020858

Published: 2023

Includes: Supplemental data

Journal Articles

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Hongwei Ren, Natalina Elliott, Bryan Lye, Joe Cross, Lucy Field, Kanagaraju Ponnusamy, Irene Roberts, Christina Halsey, Thomas Arthur Milne, Anindita Roy, Anastasios Karadimitris

Blood (2023) 142 (Supplement 1): 766.

https://doi.org/10.1182/blood-2023-186442

Published: 2023

Journal Articles

Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients

Blood (2022) 140 (Supplement 1): 1679–1681.

https://doi.org/10.1182/blood-2022-164881

Published: 2022

Journal Articles

CD34 + CD19 − CD22 + B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Blood (2022) 140 (1): 38–44.

https://doi.org/10.1182/blood.2021014840

Published: 2022

Includes: Supplemental data

Journal Articles

Base Editing Repairs the HbE Mutation Restoring the Production of Normal Globin Chains in Severe HbE/β-Thalassemia Patient Hematopoietic Stem Cells and Erythroid Cells

Mohsin Badat, Peng Hua, Sachith Mettananda, Christopher Fisher, Noemi Roy, Siobhan Rice, Anindita Roy, Douglas R. Higgs, James Davies

Blood (2021) 138 (Supplement 1): 2935.

https://doi.org/10.1182/blood-2021-153283

Published: 2021

Journal Articles

Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome

Blood (2021) 138 (Supplement 1): 214.

https://doi.org/10.1182/blood-2021-151454

Published: 2021

Journal Articles

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

Peng Hua, Joanna Hester, George Adigbli, Rong Li, Bethan Psaila, Anindita Roy, Carole J. R. Bataille, Graham M. Wynne, Thomas Jackson, Thomas A. Milne, Angela J. Russell, James Davies, Irene Roberts, Fadi Issa, Suzanne M. Watt

Blood (2020) 136 (21): 2410–2415.

https://doi.org/10.1182/blood.2020005357

Published: 2020

Includes: Supplemental data

Journal Articles

Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia

Blood (2020) 136 (Supplement 1): 1–2.

https://doi.org/10.1182/blood-2020-141535

Published: 2020

Journal Articles

A “gut feeling” about precursor B-ALL

Anindita Roy

Blood (2020) 136 (18): 1995–1996.

https://doi.org/10.1182/blood.2020008907

Published: 2020

Journal Articles

Single-cell analysis of bone marrow–derived CD34 + cells from children with sickle cell disease and thalassemia

Peng Hua, Noemi Roy, Josu de la Fuente, Guanlin Wang, Supat Thongjuea, Kevin Clark, Anindita Roy, Bethan Psaila, Neil Ashley, Yvonne Harrington, Claus Nerlov, Suzanne M. Watt, Irene Roberts, James O. J. Davies

Blood (2019) 134 (23): 2111–2115.

https://doi.org/10.1182/blood.2019002301

Published: 2019

Includes: Supplemental data

Journal Articles

Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome

Sorcha Isabella O'Byrne, BSc, Natalina Elliott, PhD, Gemma Buck, BSc, Siobhan Rice, David O'Connor, Jana Oswald, Hannah Fuchs, Ella-Mae Labbett, Nicholas James Fordham, MBBS, BSc, Anindita Roy, MD PhD, Irene Roberts

Blood (2019) 134 (Supplement_1): 1206.

https://doi.org/10.1182/blood-2019-130180

Published: 2019

Journal Articles

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Blood (2019) 134 (13): 1059–1071.

https://doi.org/10.1182/blood.2019001289

Published: 2019

Includes: Supplemental data

Journal Articles

Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia

Eleni Louka, MD, Benjamin Povinelli, PhD, Alba Rodriguez-Meira, Gemma Buck, BSc, Angela Hamblin, MD PhD, Christopher Booth, Anindita Roy, MD PhD, Natalina Elliott, PhD, Deena Iskander, MD, Josu de la Fuente, FRCP, PhD FRCPath, Nicholas James Fordham, MBBS, BSc, Sorcha Isabella Obyrne, Sarah Inglott, Anupama Gopala Rao, MB, MRCP, MRCPath, Irene Roberts, MD, Adam J Mead, MD PhD

Blood (2017) 130 (Supplement 1): 379.

https://doi.org/10.1182/blood.V130.Suppl_1.379.379

Published: 2017

Journal Articles

High Resolution Igh Repertoire Analysis Reveals the Human Fetal Liver As the Origin of Life-Long, Innate B Lymphopoiesis

Anindita Roy, MDPhD, Vojtech Bystry, Georg Bohn, Katerina Goudevenou, Tomas Reigl, Maria Papaioannou, Adam Krejci, Sorcha O'Byrne, Aristeidis Chaidos, Andrea Grioni, Nikos Darzentas, Irene Roberts, Anastasios Karadimitris

Blood (2016) 128 (22): 127.

https://doi.org/10.1182/blood.V128.22.127.127

Published: 2016

Journal Articles

Developmental Stage Specific B-Progenitor Expansion in Normal Fetal Bone Marrow Is Absent in Down Syndrome: Implications for Infant ALL

Anindita Roy, MDPhD, Georg Bohn, Katerina Goudevenou, Gillian Cowan, Neha Bhatnagar, David O'Connor, Oliver Tunstall, Jerry Chan, Phillip Bennett, Sailesh Kumar, Deena Iskander, Sarah Inglott, Binbin Liu, Philip Ancliff, Anastasios Karadimitris, Irene Roberts, MDFRCP FRCPCH FRCPath

Blood (2014) 124 (21): 4331.

https://doi.org/10.1182/blood.V124.21.4331.4331

Published: 2014

Journal Articles

Clinical and Hematologic Impact of Fetal and Perinatal Variables on Mutant GATA1 Clone Size in Neonates with Down Syndrome

Neha Bhatnagar, MBChB MRCPCH FRCPath, Kelly Perkins, Sarah Filippi, Helen Richmond, RN, Joanna Bonnici, Kate Alford, Georgina Hall, BSc, PhD MBBS, FRCP, FRCPath, Gaëtan Juban, PhD, Simon McGowan, Anindita Roy, MDPhD, Natalina Elliott, Michael Stumpf, Alice Norton, MB, Paresh Vyas, MDPhD, Irene Roberts, MDFRCP FRCPCH FRCPath

Blood (2014) 124 (21): 2349.

https://doi.org/10.1182/blood.V124.21.2349.2349

Published: 2014

NARROW

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan

The Fetal Specific Gene LIN28B Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Blinatumomab with De-Escalated Chemotherapy for Infant KMT2A -Rearranged B-Cell Acute Lymphoblastic Leukemia

A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients

CD34 + CD19 − CD22 + B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Base Editing Repairs the HbE Mutation Restoring the Production of Normal Globin Chains in Severe HbE/β-Thalassemia Patient Hematopoietic Stem Cells and Erythroid Cells

Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia

A “gut feeling” about precursor B-ALL

Single-cell analysis of bone marrow–derived CD34 + cells from children with sickle cell disease and thalassemia

Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia

High Resolution Igh Repertoire Analysis Reveals the Human Fetal Liver As the Origin of Life-Long, Innate B Lymphopoiesis

Developmental Stage Specific B-Progenitor Expansion in Normal Fetal Bone Marrow Is Absent in Down Syndrome: Implications for Infant ALL

Clinical and Hematologic Impact of Fetal and Perinatal Variables on Mutant GATA1 Clone Size in Neonates with Down Syndrome

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American Society of Hematology

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American Society of Hematology

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