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Joe Harman
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Journal Articles

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Alastair L Smith, Nicholas Denny, Catherine M Chahrour, Natalina Elliott, Thomas Jackson, Joe Harman, Huimin Geng, Irene Roberts, Nicholas Crump, James Oliver Davies, Anindita Roy, Thomas A Milne
Journal: Blood
Blood (2024) 144 (Supplement 1): 201.
https://doi.org/10.1182/blood-2024-208035
Published: 2024
Journal Articles

First-in-Class Targeted Protein Degrader of MLLT1/3 for the Treatment of Advanced AML and ALL Including Menin Inhibitor Resistant / Refractory Disease

John Pollard, Graham Craggs, Gillian Farnie, Matthew Fawkes, Fenella Gross, Joe Harman, Marta Llorca-Cardenosa, Sarah Major, Alison Maloney, Thomas A Milne, Iain Simpson
Journal: Blood
Blood (2024) 144 (Supplement 1): 2772.
https://doi.org/10.1182/blood-2024-210052
Published: 2024
Journal Articles

Novel Inhibitors of MLLT1/3, a Critical Component of the Super-Elongation Complex (SEC), Target a Range of Molecularly Defined Acute Leukemias, with a Differential Profile to Menin Inhibition

John Pollard, Graham Craggs, Gillian Farnie, Matthew Fawkes, Oleg Fedorov, Charline Giroud, Fenella Gross, Joe Harman, Alison Maloney, Thomas Arthur Milne, Iain Simpson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2789.
https://doi.org/10.1182/blood-2023-186638
Published: 2023